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Research Output 2010 2019

2019

Comparison of different chemically modified inhibitors of miR-199b in vivo

Duygu, B., Juni, R., Ottaviani, L., Bitsch, N., Wit, J. B. M., de Windt, L. J. & Martins, P. A. D. C., Jan 2019, In : Biochemical Pharmacology. 159, p. 106-115 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Interplay of N- acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs

Ali, T., Mushtaq, I., Maryam, S., Farhan, A., Saba, K., Jan, M. I., Sultan, A., Anees, M., Duygu, B., Hamera, S., Tabassum, S., Javed, Q., Martin, P. A. D. C. & Murtaza, I., Jan 2019, In : Archives of Biochemistry and Biophysics. 661, p. 56-65 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Therapeutic Delivery of miR-148a Suppresses Ventricular Dilation in Heart Failure

Raso, A., Dirkx, E., Philippen, L. E., Fernandez-Celis, A., De Majo, F., Sampaio-Pinto, V., Sansonetti, M., Juni, R., el Azzouzi, H., Calore, M., Bitsch, N., Olieslagers, S., Oerlemans, M. I. F. J., Huibers, M. M., de Weger, R. A., Reckman, Y. J., Pinto, Y. M., Zentilin, L., Zacchigna, S., Giacca, M. & 3 others, da Costa Martins, P. A., Lopez-Andres, N. & De Windt, L. J., 6 Mar 2019, In : Molecular Therapy. 27, 3, p. 584-599 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

cROSsing the cardiac MIRe: fibroblast-cardiomyocyte ex(o)press

Abreu, R. C. & Martins, P. A., 1 Jun 2018, In : American Journal of Physiology-heart and Circulatory Physiology. 314, 6, p. H1253-H1255 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Mononuclear Diploidy at the Heart of Cardiomyocyte Proliferation

da Costa Martins, P. A., 5 Oct 2017, In : Cell Stem Cell. 21, 4, p. 421-422 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Non-coding RNAs in cardiac hypertrophy

Ottaviani, L. & da Costa Martins, P. A., 15 Jun 2017, In : Journal of Physiology. 595, 12, p. 4037-4050 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia

D'Souza, A., Pearman, C. M., Wang, Y., Nakao, S., Logantha, S. J. R. J., Cox, C., Bennett, H., Zhang, Y., Johnsen, A. B., Linscheid, N., Poulsen, P. C., Elliott, J., Coulson, J., McPhee, J., Robertson, A., Martins, P. A. D. C., Kitmitto, A., Wisloff, U., Cartwright, E. J., Monfredi, O. & 5 others, Lundby, A., Dobrzynski, H., Oceandy, D., Morris, G. M. & Boyett, M. R., 13 Oct 2017, In : Circulation Research. 121, 9, p. 1058-1068 32 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Exosomes: scytales in the damaged heart

Ottaviani, L., De Windt, L. J. & da Costa Martins, P. A., Jun 2016, In : Annals of translational medicine. 4, 11, 222.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Targeting microRNAs in heart failure

Duygu, B., de Windt, L. J. & Da Costa Martins, P., Feb 2016, In : Trends in Cardiovascular Medicine. 26, 2, p. 99-110

Research output: Contribution to journalArticleAcademicpeer-review

2015
1 Citation (Scopus)

MicroRNA Expression in Myocardial Tissue and Plasma of Patients with End-Stage Heart Failure during LVAD Support: Comparison of Continuous and Pulsatile Devices

Lok, S. I., de Jonge, N., van Kuik, J., van Geffen, A. J. P., Huibers, M. M. H., van der Weide, P., Siera, E., Winkens, B., Doevendans, P. A., de Weger, R. A. & Da Costa Martins, P. A., 2 Oct 2015, In : PLOS ONE. 10, 10, e0136404.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
16 Citations (Scopus)

Non-coding RNA in control of gene regulatory programs in cardiac development and disease

Philippen, L. E., Dirkx, E., da Costa-Martins, P. A. & De Windt, L. J., Dec 2015, In : Journal of Molecular and Cellular Cardiology. 89, Pt A, p. 51-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014
78 Citations (Scopus)

Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy

Roncarati, R., Anselmi, C. V., Losi, M. A., Papa, L., Cavarretta, E., Martins, P. D. C., Contaldi, C., Jotti, G. S., Franzone, A., Galastri, L., Latronico, M. V. G., Imbriaco, M., Esposito, G., De Windt, L., Betocchi, S. & Condorelli, G., 11 Mar 2014, In : Journal of the American College of Cardiology. 63, 9, p. 920-927

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice

Poels, E. M., Bitsch, N., Slenter, J. M., Kooi, M. E., de Theije, C. C., De Windt, L. J., van Empel, V. P. & da Costa Martins, P. A., 15 Apr 2014, In : PLOS ONE. 9, 4, 7 p., 92983.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2013
37 Citations (Scopus)

A Deep Sequencing Approach to Uncover the miRNOME in the Human Heart

Leptidis, S., el Azzouzi, H., Lok, S. I., de Weger, R., Olieslagers, S., Kisters, N., Silva, G. J., Heymans, S., Cuppen, E., Berezikov, E., De Windt, L. J. & Martins, P. D. C., 27 Feb 2013, In : PLOS ONE. 8, 2, e57800.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
48 Citations (Scopus)

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

Dirkx, E., Gladka, M. M., Philippen, L. E., Armand, A-S., Kinet, V., Leptidis, S., el Azzouzi, H., Salic, K., Bourajjaj, M., da Silva, G. J. J., Olieslagers, S., van der Nagel, R., de Weger, R., Bitsch, N., Kisters, N., Seyen, S., Morikawa, Y., Chanoine, C., Heymans, S., Volders, P. G. A. & 6 others, Thum, T., Dimmeler, S., Cserjesi, P., Eschenhagen, T., Martins, P. A. D. C. & De Windt, L. J., Nov 2013, In : Nature Cell Biology. 15, 11, p. 1282-1293

Research output: Contribution to journalArticleAcademicpeer-review

Regulation of fetal gene expression in heart failure

Dirkx, E., da Costa Martins, P. A. & De Windt, L. J., Dec 2013, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1832, 12, p. 2414-2424

Research output: Contribution to journalArticleAcademicpeer-review

59 Citations (Scopus)

The Hypoxia-Inducible MicroRNA Cluster miR-199a similar to 214 Targets Myocardial PPAR delta and Impairs Mitochondrial Fatty Acid Oxidation

El Azzouzi, H., Leptidis, S., Dirkx, E., Hoeks, J., van Bree, B., van de Brand, K., McClellan, E. A., Poels, E., Sluimer, J. C., van den Hoogenhof, M. M., Armand, A. S., Yin, X., Langley, S., Bourajjaj, M., Olieslagers, S., Krishnan, J., Vooijs, M., Kurihara, H., Stubbs, A., Pinto, Y. M. & 5 others, Krek, W., Mayr, M., da Costa Martins, P. A., Schrauwen, P. & De Windt, L. J., 3 Sep 2013, In : Cell Metabolism. 18, 3, p. 341-354 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

2010

MicroRNA Regulation in Cardiovascular Disease

Martins, P. A. D. C., Leptidis, S., Salic, K. & De Windt, L. J., Aug 2010, In : Current Drug Targets. 11, 8, p. 900-906

Research output: Contribution to journalArticleAcademicpeer-review