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Research Output

Article
27 Citations (Scopus)

Energy restriction and Roux-en-Y gastric bypass reduce postprandial alpha-dicarbonyl stress in obese women with type 2 diabetes

Maessen, D. E., Hanssen, N. M., Lips, M. A., Scheijen, J. L., van Dijk, K. W., Pijl, H., Stehouwer, C. D. & Schalkwijk, C. G., Sep 2016, In : Diabetologia. 59, 9, p. 2013-2017

Research output: Contribution to journalArticleAcademicpeer-review

Glyoxalase 1 overexpression does not affect atherosclerotic lesion size and severity in ApoE(-/-) mice with or without diabetes

Hanssen, N. M. J., Brouwers, O., Gijbels, M. J., Wouters, K., Wijnands, E., Cleutjens, J. P. M., De Mey, J. G., Miyata, T., Biessen, E. A., Stehouwer, C. D. A. & Schalkwijk, C. G., 1 Oct 2014, In : Cardiovascular Research. 104, 1, p. 160-170

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype

Hanssen, N. M. J., Wouters, K., Huijberts, M. S., Gijbels, M. J., Sluimer, J. C., Scheijen, J. L. J. M., Heeneman, S., Biessen, E. A. L., Daemen, M. J. A. P., Brownlee, M., de Kleijn, D. P., Stehouwer, C. D. A., Pasterkamp, G. & Schalkwijk, C. G., May 2014, In : European Heart Journal. 35, 17, p. 1137-1146

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes

Hanssen, N. M. J., Westerink, J., Scheijen, J. L. J. M., van der Graaf, Y., Stehouwer, C. D. A. & Schalkwijk, C. G., 1 Aug 2018, In : Diabetes Care. 41, 8, p. 1689-1695 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease in Individuals With Type 1 Diabetes: A 12-Year Follow-up Study

Hanssen, N. M. J., Scheijen, J. L. J. M., Jorsal, A., Parving, H-H., Tarnow, L., Rossing, P., Stehouwer, C. D. A. & Schalkwijk, C. G., 1 Aug 2017, In : Diabetes. 66, 8, p. 2278-2283 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Methylglyoxal and glyoxalase I in atherosclerosis

Hanssen, N. M. J., Stehouwer, C. D. A. & Schalkwijk, C. G., Apr 2014, In : Biochemical Society Transactions. 42, p. 443-449

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes

Kraakman, M. J., Lee, M. K. S., Al-Sharea, A., Dragoljevic, D., Barrett, T. J., Montenont, E., Basu, D., Heywood, S., Kammoun, H. L., Flynn, M., Whillas, A., Hanssen, N. M. J., Febbraio, M. A., Westein, E., Fisher, E. A., Chin-Dusting, J., Cooper, M. E., Berger, J. S., Goldberg, I. J., Nagareddy, P. R. & 1 others, Murphy, A. J., 1 Jun 2017, In : Journal of Clinical Investigation. 127, 6, p. 2133-2147 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Plasma Advanced Glycation End Products Are Associated With Incident Cardiovascular Events in Individuals With Type 2 Diabetes: A Case-Cohort Study With a Median Follow-up of 10 Years (EPIC-NL)

Hanssen, N. M. J., Beulens, J. W. J., van Dieren, S., Scheijen, J. L. J. M., van der A, D. L., Spijkerman, A. M. W., van der Schouw, Y. T., Stehouwer, C. D. A. & Schalkwijk, C. G., Jan 2015, In : Diabetes. 64, 1, p. 257-265

Research output: Contribution to journalArticleAcademicpeer-review

25 Citations (Scopus)

Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids

Van den Eynde, M. D. G., Geleijnse, J. M., Scheijen, J. L. J. M., Hanssen, N. M. J., Dower, J. I., Afman, L. A., Stehouwer, C. D. A., Hollman, P. C. H. & Schalkwijk, C. G., Dec 2018, In : Journal of Nutrition. 148, 12, p. 1911-1916 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1

van Eupen, M. G. A., Schram, M. T., Colhoun, H. M., Hanssen, N. M. J., Niessen, H. W. M., Tarnow, L., Parving, H. H., Rossing, P., Stehouwer, C. D. A. & Schalkwijk, C. G., Aug 2013, In : Diabetologia. 56, 8, p. 1845-1855

Research output: Contribution to journalArticleAcademicpeer-review

Doctoral Thesis
Open Access
File
418 Downloads (Pure)
Review article

Dipeptidyl peptidase-4 inhibitors and cardiovascular and renal disease in type 2 diabetes: What have we learned from the CARMELINA trial?

Hanssen, N. M. J. & Jandeleit-Dahm, K. A. M., Jul 2019, In : Diabetes & Vascular Disease Research. 16, 4, p. 303-309 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease

Hanssen, N. M. J., Stehouwer, C. D. A. & Schalkwijk, C. G., Jan 2019, In : Current Opinion in Nephrology and Hypertension. 28, 1, p. 26-33 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review