Personal profile
Biography
I am a Postdoctoral Researcher in the Sustainable Foods for Health group in Venlo, with expertise in human nutrition and intestinal in vitro cell models. My research focuses on the development, characterization, and functional evaluation of sustainable next-generation proteins from crops and agroindustrial sidestreams, including their nutritional quality, digestibility, and functional properties. Using advanced in vitro digestion systems and host–microbe interaction models, I investigate how these proteins influence intestinal barrier function, immune signaling, and microbiota-mediated metabolism. My work generates mechanistic evidence to support the development of high-performance, sustainable foods that advance human and planetary health.
Keywords
- RZ Other systems of medicine
- Sustainable proteins
- Gut barrier function
- Host–microbiome interactions
- Advanced intestinal in vitro models
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Collaborations and top research areas from the last five years
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Differential stress responses of immunoisolated human islets embedded in pancreatic extracellular matrix under static and free-fall dynamic conditions
Borges-Silva, I., Mantovani, M. D. C., Danh Anh Luu, M., Gorter, A., Borghuis, T., Gasaly, N., Cleide Sogayar, M., de Vos, P. & Trombetta-Lima, M., 2025, In: Journal of Tissue Engineering. 16, 21 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Pectin-based encapsulation systems for the protection of beneficial bacterial species and impact on intestinal barrier function in vitro
Galvez-Jiron, F., Tang, X., Gasaly, N., Poncelet, D., Wandersleben, T., Drusch, S., Acevedo, F. & de Vos, P., Mar 2025, In: Food Hydrocolloids. 160, 13 p., 110765.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Pectins mitigate Candidalysin-induced gut barrier disruption and inflammation in vitro in a degree of methyl-esterification-dependent manner
Gasaly, N., Chen, X., Silva-Lagos, L., Silva, I. B. B., Hermoso, M. A. & de Vos, P., 1 Dec 2025, In: Food Hydrocolloids for Health. 8, 100232.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
A novel "microbiota-host interaction model" to study the real-time effects of fermentation of non-digestible carbohydrate (NDCs) on gut barrier function
Chen, X., Moreno, L. L., Tang, X., Gasaly, N., Schols, H. A. & de Vos, P., 2024, In: Current Research in Food Science. 8, 11 p., 100736.Research output: Contribution to journal › Article › Academic › peer-review
Open Access -
Effects of pectin's degree of methyl esterification on TLR2-mediated IL-8 secretion and tight junction gene expression in intestinal epithelial cells: influence of soluble TLR2
Gasaly, N., Tang, X., Chen, X., Bellalta, S., Hermoso, M. A. & de Vos, P., 22 Jan 2024, In: Food & Function. 15, 2, p. 569-579 11 p.Research output: Contribution to journal › Article › Academic › peer-review