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Research Output 2010 2019

2019

A bioinformatics workflow to decipher transcriptomic data from vitamin D studies

Muñoz García, A., Eijssen, L. M., Kutmon, M., Sarathy, C., Cengo, A., Hewison, M., Evelo, C. T., Lenz, M. & Coort, S. L., May 2019, In : Journal of Steroid Biochemistry and Molecular Biology. 189, p. 28-35 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

A computational model of postprandial adipose tissue lipid metabolism derived using human arteriovenous stable isotope tracer data

O'Donovan, S. D., Lenz, M., Vink, R. G., Roumans, N. J. T., de Kok, T. M. C. M., Mariman, E. C. M., Peeters, R. L. M., van Riel, N. A. W., van Baak, M. A. & Arts, I. C. W., Oct 2019, In : PLoS Computational Biology. 15, 10, 23 p., e1007400.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of biopsy samples

Garza, Z. C. F., Lenz, M., Liebmann, J., Ertaylan, G., Born, M., Arts, I. C. W., Hilbers, P. A. J. & van Riel, N. A. W., 17 Aug 2019, In : BMC Medical Genomics. 12, 1, 14 p., 121.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Leukocyte Counts Based on DNA Methylation at Individual Cytosines

Frobel, J., Bozic, T., Lenz, M., Uciechowski, P., Han, Y., Herwartz, R., Strathmann, K., Isfort, S., Panse, J., Esser, A., Birkhofer, C., Gerstenmaier, U., Kraus, T., Rink, L., Koschmieder, S. & Wagner, W., 1 Mar 2018, In : Clinical Chemistry. 64, 3, p. 566-575 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Deconvolution of the white adipose tissue cell types from whole genome gene expression profiles

Lenz, M., Peeters, R., Arts, I., de Kok, T. & Ertaylan, G., 10 Nov 2016, VPH2016, book of abstracts. Hoekstra, A. G. (ed.). Amsterdam: University of Amsterdam, p. 528-531

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademic

1 Citation (Scopus)

Estimating real cell size distribution from cross-section microscopy imaging

Lenz, M., Roumans, N. J. T., Vink, R. G., van Baak, M. A., Mariman, E. C. M., Arts, I. C. W., de Kok, T. & Ertaylan, G., 1 Sep 2016, In : Bioinformatics. 32, 17, p. i396-i404 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Estimating real cell size distribution from cross-section microscopy imaging (EstiTiCS)

Ertaylan, G., Roumans, N., Vink, R., van Baak, M., Mariman, E., Arts, I., de Kok, T. & Lenz, M., Sep 2016.

Research output: Contribution to conferencePosterAcademic

From Epidemiology to Systems Biology and back - using metabolic models in epidemiological cohort studies

Lenz, M. & Arts, I., 27 Jan 2016.

Research output: Contribution to conferenceOther (do not use)Academic

1 Citation (Scopus)

Principal components analysis and the reported low intrinsic dimensionality of gene expression microarray data

Lenz, M., Müller, F-J., Zenke, M. & Schuppert, A., 2 Jun 2016, In : Scientific Reports. 6, p. 25696 11 p., 25696.

Research output: Contribution to journalArticleAcademicpeer-review

2015
Open Access
4 Citations (Scopus)

Epigenetic biomarker to support classification into pluripotent and non-pluripotent cells

Lenz, M., Goetzke, R., Schenk, A., Schubert, C., Veeck, J., Hemeda, H., Koschmieder, S., Zenke, M., Schuppert, A. & Wagner, W., 2015, In : Scientific Reports. 5, p. 8973

Research output: Contribution to journalArticleAcademicpeer-review

Investigation of potential traces of pluripotency in germinal-center-derived B-cell lymphomas driven by MYC

Wagener, R., Lenz, M., Schuldt, B., Lenz, I., Schuppert, A., Siebert, R. & Müller, F-J., May 2015, In : Blood Cancer Journal. 5, 5, p. e317

Research output: Contribution to journalArticleAcademicpeer-review

2014

An extended gene expression landscape for the characterization and quality control of in vitro differentiated cells

Lenz, M., Malan, D., Frobel, J., Wagner, W., Sasse, P. & Schuppert, A., Nov 2014.

Research output: Contribution to conferencePosterAcademic

An extended gene expression landscape for the characterization and quality control of in vitro differentiated cells

Lenz, M., Malan, D., Frobel, J., Wagner, W., Sasse, P. & Schuppert, A., 2014.

Research output: Contribution to conferencePosterAcademic

A two-scale gene expression landscape for the characterization of in vitro differentiated cells

Lenz, M., Malan, D., Frobel, J., Wagner, W., Sasse, P. & Schuppert, A., 2014.

Research output: Contribution to conferencePosterAcademic

A two-scale gene expression landscape for the characterization of in vitro differentiated cells

Lenz, M., Malan, D., Frobel, J., Wagner, W., Sasse, P. & Schuppert, A., 2014.

Research output: Contribution to conferencePosterAcademic

34 Citations (Scopus)

Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells

Frobel, J., Hemeda, H., Lenz, M., Abagnale, G., Joussen, S., Denecke, B., Sarić, T., Zenke, M. & Wagner, W., 9 Sep 2014, In : Stem Cell Reports. 3, 3, p. 414-22 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2013
22 Citations (Scopus)

Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles

Shao, K., Koch, C., Gupta, M. K., Lin, Q., Lenz, M., Laufs, S., Denecke, B., Schmidt, M., Linke, M., Hennies, H. C., Hescheler, J., Zenke, M., Zechner, U., Šarić, T. & Wagner, W., Jan 2013, In : Molecular Therapy. 21, 1, p. 240-50 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Physiological tracking of differentiation time series using large scale gene expression analysis

Lenz, M., Schuldt, B. M., Müller, F-J. & Schuppert, A., 2013.

Research output: Contribution to conferencePosterAcademic

6 Citations (Scopus)

PhysioSpace: relating gene expression experiments from heterogeneous sources using shared physiological processes

Lenz, M., Schuldt, B. M., Müller, F-J. & Schuppert, A., 2013, In : PLOS ONE. 8, 10, p. e77627

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Power-laws and the use of pluripotent stem cell lines

Schuldt, B. M., Guhr, A., Lenz, M., Kobold, S., MacArthur, B. D., Schuppert, A., Löser, P. & Müller, F-J., 2013, In : PLOS ONE. 8, 1, p. e52068

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

To clone or not to clone? Induced pluripotent stem cells can be generated in bulk culture

Willmann, C. A., Hemeda, H., Pieper, L. A., Lenz, M., Qin, J., Joussen, S., Sontag, S., Wanek, P., Denecke, B., Schüler, H. M., Zenke, M. & Wagner, W., 2013, In : PLOS ONE. 8, 5, p. e65324

Research output: Contribution to journalArticleAcademicpeer-review

2012
78 Citations (Scopus)

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

MacArthur, B. D., Sevilla, A., Lenz, M., Müller, F-J., Schuldt, B. M., Schuppert, A. A., Ridden, S. J., Stumpf, P. S., Fidalgo, M., Ma'ayan, A., Wang, J. & Lemischka, I. R., Nov 2012, In : Nature Cell Biology. 14, 11, p. 1139-47 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

PluriTest: molecular diagnostic assay for pluripotency in human stem cells

Lenz, M., 2012, Human stem cell manual, second edition. Loring, J. F. & Peterson, S. E. (eds.). Elsevier

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

2011

Integrating quality control in the automated generation of induced pluripotent stem cells

Lenz, M., Schuldt, B. M., Goldmann, J. E. & Schuppert, A., 2011.

Research output: Contribution to conferencePosterAcademic

3 Citations (Scopus)

Joint EEG/fMRI state space model for the detection of directed interactions in human brains--a simulation study

Lenz, M., Musso, M., Linke, Y., Tüscher, O., Timmer, J., Weiller, C. & Schelter, B., Nov 2011, In : Physiological Measurement. 32, 11, p. 1725-36 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

2010

Joint EEG/fMRI state space model for the detection of directed interactions in human brains

Lenz, M., Musso, M., Linke, Y., Tüscher, O., Timmer, J., Weiller, C. & Schelter, B., 2010.

Research output: Contribution to conferenceAbstractAcademic