Marike van Gisbergen

Research output

Research output per year 2015 2017 2020 2024

• 17 Article
• 2 (Systematic) Review article
• 1 Doctoral Thesis

Research output per year

Research output per year

Search results

• 2015

  How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models

  van Gisbergen, M. W., Voets, A. M., Starmans, M. H. W., de Coo, I. F. M., Yadak, R., Hoffmann, R. F., Boutros, P. C., Smeets, H. J. M., Dubois, L. & Lambin, P., 2015, In: Mutation Research-Reviews in Mutation Research. 764, p. 16-30

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• New ways to image and target tumour hypoxia and its molecular responses

  Dubois, L. J., Niemans, R., van Kuijk, S. J. A., Panth, K. M., Parvathaneni, N-K., Peeters, S. G. J. A., Zegers, C. M. L., Rekers, N. H., van Gisbergen, M. W., Biemans, R., Lieuwes, N. G., Spiegelberg, L., Yaromina, A., Winum, J-Y., Vooijs, M. & Lambin, P., Sept 2015, In: Radiotherapy and Oncology. 116, 3, p. 352-357

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2016

  Chemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer Cells

  van Gisbergen, M. W., Cebula, M., Zhang, J., Ottosson-Wadlund, A., Dubois, L., Lambin, P., Tew, K. D., Townsend, D. M., Haenen, G. R. M. M., Drittij - Reijnders, M. J., Saneyoshi, H., Araki, M., Shishido, Y., Ito, Y., Arner, E. S. J., Abe, H., Morgenstern, R. & Johansson, K., Jun 2016, In: Molecular Pharmaceutics. 13, 6, p. 2010-2025

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  68 Downloads (Pure)
• 2017

  Distinct radiation responses after in vitro mtDNA depletion are potentially related to oxidative stress

  van Gisbergen, M. W., Voets, A. M., Biemans, R., Hoffmann, R. F., Drittij-Reijnders, M-J., Haenen, G. R. M. M., Heijink, I. H., Rouschop, K. M. A., Dubois, L. J. & Lambin, P., 3 Aug 2017, In: PLOS ONE. 12, 8, 13 p., 0182508.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Mitochondrial Neurogastrointestinal Encephalomyopathy Caused by Thymidine Phosphorylase Enzyme Deficiency: From Pathogenesis to Emerging Therapeutic Options

  Yadak, R., Smitt, P. S., van Gisbergen, M. W., van Til, N. P. & de Coo, I. F. M., 15 Feb 2017, In: Frontiers in Cellular Neuroscience. 11, 14 p., 31.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs

  van Kuijk, S. J. A., Parvathaneni, N. K., Niemans, R., van Gisbergen, M. W., Carta, F., Vullo, D., Pastorekova, S., Yaromina, A., Supuran, C. T., Dubois, L. J., Winurn, J-Y. & Lambin, P., 15 Feb 2017, In: European Journal of Medicinal Chemistry. 127, p. 691-702 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2018

  Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans

  Nascimento, E. B. M., Sparks, L. M., Divoux, A., van Gisbergen, M. W., Broeders, E. P. M., Jorgensen, J. A., Schaart, G., Bouvy, N. D., van Marken Lichtenbelt, W. D. & Schrauwen, P., 1 Jan 2018, In: Obesity. 26, 1, p. 135-140 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  107 Downloads (Pure)

• Targeting glucose and glutamine metabolism combined with radiation therapy in non-small cell lung cancer

  Meijer, T. W. H., Peeters, W. J. M., Dubois, L. J., van Gisbergen, M. W., Biemans, R., Venhuizen, J-H., Span, P. N. & Bussink, J., Dec 2018, In: Lung Cancer. 126, p. 32-40 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  240 Downloads (Pure)
• 2019

  Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy

  van Tienen, F., Zelissen, R., Timmer, E., van Gisbergen, M., Lindsey, P., Quattrocelli, M., Sampaolesi, M., Mulder-den Hartog, E., de Coo, I. & Smeets, H., 21 Dec 2019, In: Stem Cell Research & Therapy. 10, 1, 10 p., 405.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

  Roig, E. M., Groot, A. J., Yaromina, A., Hendrickx, T. C., Barbeau, L. M. O., Giuranno, L., Dams, G., Ient, J., Pimentel, V. O., van Gisbergen, M. W., Dubois, L. J. & Vooijs, M. A., Jan 2019, In: Cells. 8, 1, 15 p., 45.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2020

  Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells

  Grasso, D., Medeiros, H. C. D., Zampieri, L. X., Bol, V., Danhier, P., van Gisbergen, M. W., Bouzin, C., Brusa, D., Gregoire, V., Smeets, H., Stassen, A. P. M., Dubois, L. J., Lambin, P., Dutreix, M. & Sonveaux, P., 13 Mar 2020, In: Frontiers in Pharmacology. 11, 16 p., 263.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets

  van Gisbergen, M. W., Offermans, K., Voets, A. M., Lieuwes, N. G., Biemans, R., Hoffmann, R. F., Dubois, L. J. & Lambin, P., 19 May 2020, In: Frontiers in Oncology. 10, 12 p., 770.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Nitroglycerin as a radiosensitizer in non-small cell lung cancer: Results of a prospective imaging-based phase II trial

  Reymen, B. J. T., van Gisbergen, M. W., Even, A. J. G., Zegers, C. M. L., Das, M., Vegt, E., Wildberger, J. E., Mottaghy, F. M., Yaromina, A., Dubois, L. J., van Elmpt, W., De Ruysscher, D. & Lambin, P., Mar 2020, In: Clinical and Translational Radiation Oncology. 21, p. 49-55 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2022

  ATG12 deficiency results in intracellular glutamine depletion, abrogation of tumor hypoxia and a favorable prognosis in cancer

  Keulers, T. G., Koch, A., van Gisbergen, M. W., Barbeau, L. M. O., Zonneveld, M. I., de Jong, M. C., Savelkouls, K. G. M., Wanders, R. G., Bussink, J., Melotte, V. & Rouschop, K. M. A., 3 Aug 2022, In: Autophagy. 18, 8, p. 1898-1914 17 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  Mitochondrial DNA D-loop variants correlate with a primary open-angle glaucoma subgroup

  Vallbona-Garcia, A., Lindsey, P. J., Kamps, R., Stassen, A. P. M., Nguyen, N., van Tienen, F. H. J., Hamers, I. H. J., Hardij, R., van Gisbergen, M. W., Benedikter, B. J., de Coo, I. F. M., Webers, C. A. B., Gorgels, T. G. M. F. & Smeets, H. J. M., 1 Jan 2023, In: Frontiers in Ophthalmology. 3, 1309836.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs

  Côrte-Real, B. F., Hamad, I., Arroyo Hornero, R., Geisberger, S., Roels, J., Van Zeebroeck, L., Dyczko, A., van Gisbergen, M. W., Kurniawan, H., Wagner, A., Yosef, N., Weiss, S. N. Y., Schmetterer, K. G., Schröder, A., Krampert, L., Haase, S., Bartolomaeus, H., Hellings, N., Saeys, Y., Dubois, L. J., & 8 othersBrenner, D., Kempa, S., Hafler, D. A., Stegbauer, J., Linker, R. A., Jantsch, J., Müller, D. N. & Kleinewietfeld, M., 7 Feb 2023, In: Cell Metabolism. 35, 2, p. 299-315.e8 18 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  11 Downloads (Pure)
• 2024

  Influence of pathogenic filaggrin variants on dupilumab treatment in atopic dermatitis

  Clabbers, J., Boesjes, C., Spekhorst, L., van Gisbergen, M. W., Maas, E., Marshall, J., Janssen, R., Janssen, M., Zuithoff, N. P. A., Steijlen, P., de Graaf, M., van Geel, M., de Bruin-Weller, M. & Gostynski, A., Apr 2024, In: Journal of Allergy and Clinical Immunology. 153, 4, p. 1155-1161.e4

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access