20012019

Research output per year

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Research Output

Article

Abnormal bone turnover in long-standing Crohn's disease in remission.

Schoon, E. J., Geerling, B. J., van Dooren, I. M. A., Schurgers, L. J., Vermeer, C., Brummer, R. J. M. & Stockbrügger, R. W., 1 Jan 2001, In : Alimentary Pharmacology & Therapeutics. 15, 6, p. 783-792 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

38 Citations (Scopus)

A Combination of Tamarindus indica seeds and Curcuma longa Rhizome Extracts Improves Knee Joint Function and Alleviates Pain in Non-Arthritic Adults Following Physical Activity

Rao, P. S., Ramanjaneyulu, Y. S., Prisk, V. R. & Schurgers, L. J., 2019, In : International Journal of Medical Sciences. 16, 6, p. 845-853 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Administration of vitamin K does not counteract the ectopic mineralization of connective tissues in Abcc6(-/-) mice, a model for pseudoxanthoma elasticum

Jiang, Q., Li, Q., Grand-Pierre, A. E., Schurgers, L. J. & Uitto, J., 15 Feb 2011, In : Cell Cycle. 10, 4, p. 701-707

Research output: Contribution to journalArticleAcademicpeer-review

Analysis of Calcifications in Patients with Coral Reef Aorta

Schlieper, G., Grotemeyer, D., Aretz, A., Schurgers, L. J., Krueger, T., Rehbein, H., Weirich, T. E., Westenfeld, R., Brandenburg, V. M., Eitner, F., Mayer, J., Floege, J., Sandmann, W. & Ketteler, M., Apr 2010, In : Annals of Vascular Surgery. 24, 3, p. 408-414

Research output: Contribution to journalArticleAcademicpeer-review

AnnexinA5-pHrodo: a new molecular probe for measuring efferocytosis

Stoehr, R., Deckers, N., Schurgers, L., Marx, N. & Reutelingsperger, C. P., 7 Dec 2018, In : Scientific Reports. 8, 9 p., 17731.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Annexin A5 reduces early plaque formation in ApoE -/- mice

Stoehr, R., Schurgers, L., van Gorp, R., Jaminon, A., Marx, N. & Reutelingsperger, C., 21 Dec 2017, In : PLOS ONE. 12, 12, 8 p., 0190229.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Novel Biomimetic Tool for Assessing Vitamin K Status Based on Molecularly Imprinted Polymers

Eersels, K., Diliën, H., Lowdon, J., Steen Redeker, E., Rogosic, R., Heidt, B., Peeters, M., Cornelis, P., Lux, P., Reutelingsperger, C., Schurgers, L., Cleij, T. & van Grinsven, B., 11 Jun 2018, In : Nutrients. 10, 6, p. 751 12 p., 751.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Anticoagulant effect of dietary fish oil in hyperlipidemia: a study of hepatic gene expression in APOE2 knock-in mice.

Vanschoonbeek, K., Wouters, K., van der Meijden, P. E., van Gorp, P. J. J., Feijge, M. A., Herfs, M., Schurgers, L. J., Hofker, M. H., de Maat, M. P. & Heemskerk, J. W., 1 Jan 2008, In : Arteriosclerosis Thrombosis and Vascular Biology. 28, 11, p. 2023-2029

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

An Unusual Severe Vascular Case of Pseudoxanthoma Elasticum Presenting as Generalized Arterial Calcification of Infancy

Le Boulanger, G., Labreze, C., Croue, A., Schurgers, L. J., Chassaing, N., Wittkampf, T., Rutsch, F. & Martin, C. L., Jan 2010, In : American Journal of Medical Genetics Part A. 152A, 1, p. 118-123

Research output: Contribution to journalArticleAcademicpeer-review

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice

Burgmaier, M., Schutters, K., Willems, B., Van der Vorst, E. P. C., Kusters, D., Chatrou, M., Norling, L., Biessen, E. A. L., Cleutjens, J., Perretti, M., Schurgers, L. J. & Reutelingsperger, C., Oct 2014, In : Journal of Cellular and Molecular Medicine. 18, 10, p. 2117-2124

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Apolipoprotein E Regulates Amyloid Formation within Endosomes of Pigment Cells

van Niel, G., Bergam, P., Di Cicco, A., Hurbain, I., Lo Cicero, A., Dingli, F., Palmulli, R., Fort, C., Potier, M. C., Schurgers, L. J., Loew, D., Levy, D. & Raposo, G., 6 Oct 2015, In : Cell Reports. 13, 1, p. 43-51

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Arterial calcifications

Rennenberg, R. J. W. M., Schurgers, L. J., Kroon, A. A. & Stehouwer, C. D. A., 1 Jan 2010, In : Journal of Cellular and Molecular Medicine. 14, 9, p. 2203-2210

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Scopus)

Association of vitamin K status with adiponectin and body composition in healthy subjects: uncarboxylated osteocalcin is not associated with fat mass and body weight

Knapen, M. H. J., Schurgers, L. J., Shearer, M. J., Newman, P., Theuwissen, E. & Vermeer, C., 28 Sep 2012, In : British Journal of Nutrition. 108, 6, p. 1017-1024

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly

Ueland, T., Fougner, S. L., Godang, K., Lekva, T., Schurgers, L. J., Scholz, H., Halvorsen, B., Schreiner, T., Aukrust, P. & Bollerslev, J., Jan 2010, In : Journal of Clinical Endocrinology & Metabolism. 95, 1, p. 361-368

Research output: Contribution to journalArticleAcademicpeer-review

Atypical Presentation of Pseudoxanthoma Elasticum With Abdominal Cutis Laxa: Evidence for a Spectrum of Ectopic Calcification Disorders?

Vanakker, O. M., Leroy, B. P., Schurgers, L. J., Vermeer, C., Coucke, P. J. & De Paepe, A., Nov 2011, In : American Journal of Medical Genetics Part A. 155A, 11, p. 2855-2859

Research output: Contribution to journalArticleAcademicpeer-review

Calcium Regulates Key Components of Vascular Smooth Muscle Cell-Derived Matrix Vesicles to Enhance Mineralization

Kapustin, A. N., Davies, J. D., Reynolds, J. L., McNair, R., Jones, G. T., Sidibe, A., Schurgers, L. J., Skepper, J. N., Proudfoot, D., Mayr, M. & Shanahan, C. M., 24 Jun 2011, In : Circulation Research. 109, 1, p. E1-U41

Research output: Contribution to journalArticleAcademicpeer-review

Calcium scores and matrix Gla protein levels: association with vitamin K status

Rennenberg, R. J. M. W., de Leeuw, P. W., Kessels, A. G. H., Schurgers, L. J., Vermeer, C., van Engelshoven, J. M. A., Kemerink, G. J. & Kroon, A. A., Apr 2010, In : European Journal of Clinical Investigation. 40, 4, p. 344-349

Research output: Contribution to journalArticleAcademicpeer-review

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE(-/-) Mice

Donners, M. M. P. C., Bai, L., Lutgens, S., Wijnands, E., Johnson, J., Schurgers, L. J., Liu, C-L., Daemen, M., Cleutjens, K. B. J. M., Shi, G-P., Biessen, E. A. L. & Heeneman, S., 16 Sep 2016, In : PLOS ONE. 11, 9, e0162595.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cell surface-expressed phosphatidylserine as therapeutic target to enhance phagocytosis of apoptotic cells

Schutters, K., Kusters, D. H. M., Chatrou, M. L. L., Montero-Melendez, T., Donners, M., Deckers, N. M., Krysko, D. V., Vandenabeele, P., Perretti, M., Schurgers, L. J. & Reutelingsperger, C. P. M., Jan 2013, In : Cell Death and Differentiation. 20, 1, p. 49-56

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

Characterisation and potential diagnostic value of circulating matrix Gla protein (MGP) species

Cranenburg, E. C. M., Koos, R., Schurgers, L. J., Magdeleyns, E. J. P., Schoonbrood, T. H. M., Landewe, R. B., Brandenburg, V. M., Bekers, O. & Vermeer, C., Oct 2010, In : Thrombosis and Haemostasis. 104, 4, p. 811-822

Research output: Contribution to journalArticleAcademicpeer-review

Cheese and Healthy Diet: Associations With Incident Cardio-Metabolic Diseases and All-Cause Mortality in the General Population

Dekker, L. H., Vinke, P. C., Riphagen, I. J., Minovic, I., Eggersdorfer, M. L., van den Heuvel, E. G. H. M., Schurgers, L. J., Kema, I. P., Bakker, S. J. L. & Navis, G., 17 Dec 2019, In : Frontiers in nutrition. 6, 9 p., 185.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chronic coumarin treatment is associated with increased extracoronary arterial calcification in humans

Rennenberg, R. J. M. W., van Varik, B. J., Schurgers, L. J., Hamulyak, K., ten Cate, H., Leiner, T., Vermeer, C., de Leeuw, P. W. & Kroon, A. A., 17 Jun 2010, In : Blood. 115, 24, p. 5121-5123

Research output: Contribution to journalArticleAcademicpeer-review

Chronic Kidney Disease Circulating Calciprotein Particles and Extracellular Vesicles Promote Vascular Calcification: A Role for GRP (Gla-Rich Protein)

Viegas, C. S. B., Santos, L., Macedo, A. L., Matos, A. A., Silva, A. P., Neves, P. L., Staes, A., Gevaert, K., Morais, R., Vermeer, C., Schurgers, L. & Simes, D. C., 1 Mar 2018, In : Arteriosclerosis Thrombosis and Vascular Biology. 38, 3, p. 575-587 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Chronic Mineral Dysregulation Promotes Vascular Smooth Muscle Cell Adaptation and Extracellular Matrix Calcification

Shroff, R. C., McNair, R., Skepper, J. N., Figg, N., Schurgers, L. J., Deanfield, J., Rees, L. & Shanahan, C. M., Jan 2010, In : Journal of the American Society of Nephrology. 21, 1, p. 103-112

Research output: Contribution to journalArticleAcademicpeer-review

Circulating annexin A5 levels are associated with carotid intima-media thickness but not coronary plaque composition

Burgmaier, M., Reith, S., Schurgers, L., Kahles, F., Marx, N. & Reutelingsperger, C., Sep 2017, In : Diabetes & Vascular Disease Research. 14, 5, p. 415-422 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Circulating annexin A5 predicts mortality in patients with heart failure

Schurgers, L. J., Burgmaier, M., Ueland, T., Schutters, K., Aakhus, S., Hofstra, L., Gullestad, L., Aukrust, P., Hellmich, M., Narula, J. & Reutelingsperger, C. P., Jan 2016, In : Journal of Internal Medicine. 279, 1, p. 89-97

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Circulating levels of non-phosphorylated undercarboxylated matrix Gla protein are associated with disease severity in patients with chronic heart failure

Ueland, T., Dahl, C. P., Gullestad, L., Aakhus, S., Broch, K., Skardal, R., Vermeer, C., Aukrust, P. & Schurgers, L. J., Aug 2011, In : Clinical Science. 121, 3-4, p. 119-127

Research output: Contribution to journalArticleAcademicpeer-review

Circulating matrix gamma-carboxyglutamate protein (MGP) species are refractory to vitamin K treatment in a new case of Keutel syndrome

Cranenburg, E. C. M., van Spaendonck-Zwarts, K. Y., Bonafe, L., Crettol, L. M., Rodiger, L. A., Dikkers, F. G., van Essen, A. J., Superti-Furga, A., Alexandrakis, E., Vermeer, C., Schurgers, L. J. & Laverman, G. D., Jun 2011, In : Journal of Thrombosis and Haemostasis. 9, 6, p. 1225-1235

Research output: Contribution to journalArticleAcademicpeer-review

Circulating matrix Gla protein is associated with coronary artery calcification and vitamin K status in healthy women

Dalmeijer, G. W., van der Schouw, Y. T., Vermeer, C., Magdeleyns, E. J., Schurgers, L. J. & Beulens, J. W. J., Apr 2013, In : Journal of Nutritional Biochemistry. 24, 4, p. 624-628

Research output: Contribution to journalArticleAcademicpeer-review

33 Citations (Scopus)

Circulating Nonphosphorylated Carboxylated Matrix Gla Protein Predicts Survival in ESRD

Schlieper, G., Westenfeld, R., Krueger, T., Cranenburg, E. C., Magdeleyns, E. J. P., Brandenburg, V. M., Djuric, Z., Damjanovic, T., Ketteler, M., Vermeer, C., Dimkovic, N., Floege, J. & Schurgers, L. J., Feb 2011, In : Journal of the American Society of Nephrology. 22, 2, p. 387-395

Research output: Contribution to journalArticleAcademicpeer-review

Decreased Levels of Circulating Carboxylated Osteocalcin in Children with Low Energy Fractures: A Pilot Study

Popko, J., Karpinski, M., Chojnowska, S., Maresz, K., Milewski, R., Badmaev, V. & Schurgers, L. J., 1 Jun 2018, In : Nutrients. 10, 6, 7 p., 734.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Desphospho-Uncarboxylated Matrix-Gla Protein Is Increased Postoperatively in Cardiovascular Risk Patients

Dahlberg, S., Ede, J., Schurgers, L., Vermeer, C., Kander, T., Klarin, B. & Schott, U., 1 Jan 2018, In : Nutrients. 10, 1, 11 p., 46.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
7 Citations (Scopus)

Does statins promote vascular calcification in chronic kidney disease?

Chen, Z., Qureshi, A. R., Parini, P., Hurt-Camejo, E., Ripsweden, J., Brismar, T. B., Barany, P., Jaminon, A. M., Schurgers, L. J., Heimburger, O., Lindholm, B. & Stenvinkel, P., Feb 2017, In : European Journal of Clinical Investigation. 47, 2, p. 137-148 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ectopic calcification in beta-thalassemia patients is associated with increased oxidative stress and lower MGP carboxylation

Boraldi, F., Garcia-Fernandez, M., Paolinelli-deVincenzi, C., Annovi, G., Schurgers, L., Vermeer, C., Cianciulli, P., Ronchetti, I. & Quaglino, D., Dec 2013, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1832, 12, p. 2077-2084

Research output: Contribution to journalArticleAcademicpeer-review

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults

van Ballegooijen, A. J., Beulens, J. J., Schurgers, L. J., de Koning, E. J., Lips, P., van Schoor, N. M. & Vervloet, M. G., Feb 2019, In : Nutrients. 11, 2, 10 p., 231.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of antitumour necrosis factor-alpha therapy on bone turnover in patients with active Crohn's disease: a prospective study.

Ryan, B. M., Russel, M. G. V. M., Schurgers, L. J., Wichers, M. C., Sijbrandij, J., Stockbrügger, R. W. & Schoon, E. J., 1 Jan 2004, In : Alimentary Pharmacology & Therapeutics. 20, 8, p. 851-7

Research output: Contribution to journalArticleAcademicpeer-review

46 Citations (Scopus)

Effect of low-dose supplements of menaquinone-7 (vitamin K-2) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers

Theuwissen, E., Teunissen, K. J., Spronk, H. M. H., Hamulyak, K., Ten Cate, H., Shearer, M. J., Vermeer, C. & Schurgers, L. J., Jun 2013, In : Journal of Thrombosis and Haemostasis. 11, 6, p. 1085-1092

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Effect of Vitamin K-2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial

Westenfeld, R., Krueger, T., Schlieper, G., Cranenburg, E. C. M., Magdeleyns, E. J. P., Heidenreich, S., Holzmann, S., Vermeer, C., Jahnen-Dechent, W., Ketteler, M., Floege, J. & Schurgers, L. J., Feb 2012, In : American Journal of Kidney Diseases. 59, 2, p. 186-195

Research output: Contribution to journalArticleAcademicpeer-review

High-Dose Menaquinone-7 Supplementation Reduces Cardiovascular Calcification in a Murine Model of Extraosseous Calcification

Scheiber, D., Veulemans, V., Horn, P., Chatrou, M. L., Potthoff, S. A., Kelm, M., Schurgers, L. J. & Westenfeld, R., Aug 2015, In : Nutrients. 7, 8, p. 6991-7011

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Hydrolysed Formula Is a Risk Factor for Vitamin K Deficiency in Infants With Unrecognised Cholestasis

van Hasselt, P. M., de Vries, W., de Vries, E., Kok, K., Cranenburg, E. C. M., de Koning, T. J., Schurgers, L. J., Verkade, H. J. & Houwen, R. H. J., Dec 2010, In : Journal of Pediatric Gastroenterology and Nutrition. 51, 6, p. 773-776

Research output: Contribution to journalArticleAcademicpeer-review

Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S

Van de Vijver, P., Schmitt, M., Suylen, D., Scheer, L., Thomassen, M. C. L. G. D., Schurgers, L. J., Griffin, J. H., Koenen, R. R. & Hackeng, T. M., 28 Nov 2012, In : Journal of the American Chemical Society. 134, 47, p. 19318-19321

Research output: Contribution to journalArticleAcademicpeer-review

Influence of pH and phosphate concentration on the phosphate binding capacity of five contemporary binders. An in vitro study

Schumacher, S. P., Schurgers, L. J., Vervloet, M. G. & Neradova, A., Feb 2019, In : Nephrology. 24, 2, p. 221-226 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis

Chatrou, M. L. L., Cleutjens, J. P., van der Vusse, G. J., Roijers, R. B., Mutsaers, P. H. A. & Schurgers, L. J., 10 Nov 2015, In : PLOS ONE. 10, 11, e0142335.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Lack of evidence does not justify neglect: how can we address unmet medical needs in calciphylaxis?

Brandenburg, V. M., Evenepoel, P., Floege, J., Goldsmith, D., Kramann, R., Massy, Z., Mazzaferro, S., Schurgers, L. J., Sinha, S., Torregrosa, V., Urena-Torres, P., Vervloet, M. & Cozzolino, M., Aug 2016, In : Nephrology Dialysis Transplantation. 31, 8, p. 1211-1219

Research output: Contribution to journalArticleAcademicpeer-review

Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects

Theuwissen, E., Cranenburg, E. C., Knapen, M. H., Magdeleyns, E. J., Teunissen, K. J., Schurgers, L. J., Smit, E. & Vermeer, C., 14 Nov 2012, In : British Journal of Nutrition. 108, 9, p. 1652-1657

Research output: Contribution to journalArticleAcademicpeer-review

Low serum and bone vitamin K status in patients with longstanding Crohn's disease: another pathogenetic factor of osteoporosis in Crohn's disease?

Schoon, E. J., Muller, M. C. A., Vermeer, C., Schurgers, L. J., Brummer, R. J. M. & Stockbrügger, R. W., 1 Jan 2001, In : Gut. 48, 4, p. 473-477 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

78 Citations (Scopus)