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Research Output 2011 2019

2019

Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples

Hoogman, M., Muetzel, R., Guimaraes, J. P., Shumskaya, E., Mennes, M., Zwiers, M. P., Jahanshad, N., Sudre, G., Wolfers, T., Earl, E. A., Soliva Vila, J. C., Vives-Gilabert, Y., Khadka, S., Novotny, S. E., Hartman, C. A., Heslenfeld, D. J., Schweren, L. J. S., Ambrosino, S., Oranje, B., de Zeeuw, P. & 95 others, Chaim-Avancini, T. M., Rosa, P. G. P., Zanetti, M., Malpas, C. B., Kohls, G., von Polier, G. G., Seitz, J., Biederman, J., Doyle, A. E., Dale, A. M., van Erp, T. G. M., Epstein, J. N., Jernigan, T. L., Baur-Streubel, R., Ziegler, G. C., Zierhut, K. C., Schrantee, A., Hovik, M. F., Lundervold, A. J., Kelly, C., McCarthy, H., Skokauskas, N., Tuura, R. L. OG., Calvo, A., Lera-Miguel, S., Nicolau, R., Chantiluke, K. C., Christakou, A., Vance, A., Cercignani, M., Gabel, M. C., Asherson, P., Baumeister, S., Brandeis, D., Hohmann, S., Bramati, I. E., Tovar-Moll, F., Fallgatter, A. J., Kardatzki, B., Schwarz, L., Anikin, A., Baranov, A., Gogberashvili, T., Kapilushniy, D., Solovieva, A., El Marroun, H., White, T., Karkashadze, G., Namazova-Baranova, L., Ethofer, T., Mattos, P., Banaschewski, T., Coghill, D., Plessen, K. J., Kuntsi, J., Mehta, M. A., Paloyelis, Y., Harrison, N. A., Bellgrove, M. A., Silk, T. J., Cubillo, A., Rubia, K., Lazaro, L., Brem, S., Walitza, S., Frodl, T., Zentis, M., Castellanos, F. X., Yoncheva, Y. N., Haavik, J., Reneman, L., Conzelmann, A., Lesch, K-P., Pauli, P., Reif, A., Tamm, L., Konrad, K., Weiss, E. O., Busatto, G. F., Louza, M. R., Durston, S., Hoekstra, P. J., Oosterlaan, J., Stevens, M. C., Antoni Ramos-Quiroga, J., Vilarroya, O., Fair, D. A., Nigg, J. T., Thompson, P. M., Buitelaar, J. K., Faraone, S., Shaw, P., Tiemeier, H., Bralten, J. & Franke, B., Jul 2019, In : American Journal of Psychiatry. 176, 7, p. 531-542 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Brain serotonin deficiency affects female aggression

Kaestner, N., Richter, S. H., Urbanik, S., Kunert, J., Waider, J., Lesch, K-P., Kaiser, S. & Sachser, N., 4 Feb 2019, In : Scientific Reports. 9, 9 p., 1366.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Common brain disorders are associated with heritable patterns of apparent aging of the brain

Kaufmann, T., van der Meer, D., Nhat Trung Doan, Schwarz, E., Lund, M. J., Agartz, I., Alnaes, D., Barch, D. M., Baur-Streubel, R., Bertolino, A., Bettella, F., Beyer, M. K., Boen, E., Borgwardt, S., Brandt, C. L., Buitelaar, J., Celius, E. G., Cervenka, S., Conzelmann, A., Cordova-Palomera, A. & 30 others, Dale, A. M., de Quervain, D. J. F., Carlo, P., Djurovic, S., Dorum, E. S., Eisenacher, S., Elvsashagen, T., Espeseth, T., Fatouros-Bergman, H., Flyckt, L., Franke, B., Frei, O., Haatveit, B., Haberg, A. K., Harbo, H. F., Hartman, C. A., Heslenfeld, D., Hoekstra, P. J., Hogestol, E. A., Jernigan, T. L., Jonassen, R., Jonsson, E. G., Kirsch, P., Ktoszewska, I., Kolskar, K. K., Landro, N. I., Hellard, S., Lesch, K-P., Lovestone, S. & Lundervold, A., Oct 2019, In : Nature Neuroscience. 22, 10, p. 1617-+ 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cross-species models of attention-deficit/hyperactivity disorder and autism spectrum disorder: lessons from CNTNAP2, ADGRL3, and PARK2

Dalla Vecchia, E., Mortimer, N., Palladino, V. S., Kittel-Schneider, S., Lesch, K-P., Reif, A., Schenck, A. & Norton, W. H. J., Feb 2019, In : Psychiatric Genetics. 29, 1, p. 1-17 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

Demontis, D., Walters, R. K., Martin, J., Mattheisen, M., Als, T. D., Agerbo, E., Baldursson, G., Belliveau, R., Bybjerg-Grauholm, J., Baekvad-Hansen, M., Cerrato, F., Chambert, K., Churchhouse, C., Dumont, A., Eriksson, N., Gandal, M., Goldstein, J. I., Grasby, K. L., Grove, J., Gudmundsson, O. O. & 31 others, Hansen, C. S., Hauberg, M. E., Hollegaard, M. V., Howrigan, D. P., Huang, H., Maller, J. B., Martin, A. R., Martin, N. G., Moran, J., Pallesen, J., Palmer, D. S., Pedersen, C. B., Pedersen, M. G., Poterba, T., Poulsen, J. B., Ripke, S., Robinson, E. B., Satterstrom, F. K., Stefansson, H., Stevens, C., Turley, P., Walters, G. B., Won, H., Wright, M. J., Andreassen, O. A., Asherson, P., Burton, C. L., Boomsma, D. I., Cormand, B., Dalsgaard, S. & Lesch, K-P., Jan 2019, In : Nature Genetics. 51, 1, p. 63-75 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation

Mortimer, N., Ganster, T., O'Leary, A., Popp, S., Freudenberg, F., Reif, A., Soler Artigas, M., Ribases, M., Antoni Ramos-Quiroga, J., Lesch, K-P. & Rivero, O., 15 Sep 2019, In : Neuropharmacology. 156, 17 p., 107557.

Research output: Contribution to journalArticleAcademicpeer-review

Early-life stress impairs developmental programming in Cadherin 13 (CDH13)-deficient mice

Kiser, D. P., Popp, S., Schmitt-Boehrer, A. G., Strekalova, T., van den Hove, D. L., Lesch, K-P. & Rivero, O., 8 Mar 2019, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 89, p. 158-168 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Family-based association study on functional -synuclein polymorphisms in attention-deficit/hyperactivity disorder

Gerlach, M., Sharma, M., Romanos, M., Lesch, K-P., Walitza, S., Conzelmann, H. A., Krueger, R. & Renner, T. J., Mar 2019, In : ADHD Attention deficit and hyperactivity disorders. 11, 1, p. 107-111 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish

Reuter, I., Jaeckels, J., Kneitz, S., Kuper, J., Lesch, K-P. & Lillesaar, C., Jun 2019, In : Biology Open. 8, 6, p. 1-16 16 p., 040683.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala

Weidner, M. T., Lardenoije, R., Eijssen, L., Mogavero, F., De Groodt, L. P. M. T., Popp, S., Palme, R., Foerstner, K. U., Strekalova, T., Steinbusch, H. W. M., Schmitt-Boehrer, A. G., Glennon, J. C., Waider, J., van den Hove, D. L. A. & Lesch, K-P., 10 May 2019, In : Frontiers in Neuroscience. 13, 17 p., 460.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice

Jeanclos, E., Albersen, M., Ramos, R. J. J., Raab, A., Wilhelm, C., Hommers, L., Lesch, K-P., Verhoeven-Duif, N. M. & Gohla, A., Jan 2019, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1865, 1, p. 193-205 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

Stegner, D., Hofmann, S., Schuhmann, M. K., Kraft, P., Herrmann, A. M., Popp, S., Hoehn, M., Popp, M., Klaus, V., Post, A., Kleinschnitz, C., Braun, A., Meuth, S. G., Lesch, K-P., Stoll, G., Kraft, R. & Nieswandt, B., Nov 2019, In : Stroke. 50, 11, p. 3238-3245 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuroinflammation and aberrant hippocampal plasticity in a mouse model of emotional stress evoked by exposure to ultrasound of alternating frequencies

Pavlov, D., Bettendorff, L., Gorlova, A., Olkhovik, A., Kalueff, A., Ponomarev, E. D., Inozemtsev, A., Chekhonin, V., Lesch, K-P., Anthony, D. C. & Strekalova, T., 2 Mar 2019, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, p. 104-116 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Relapse of drunk driving and association with traffic accidents, alcohol-related problems and biomarkers of impulsivity

Tokko, T., Eensoo, D., Vaht, M., Lesch, K-P., Reif, A. & Harro, J., Apr 2019, In : Acta Neuropsychiatrica. 31, 2, p. 84-92 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity

Waider, J., Popp, S., Mlinar, B., Montalbano, A., Bonfiglio, F., Aboagye, B., Thuy, E., Kern, R., Thiel, C., Araragi, N., Svirin, E., Schmitt-Boehrer, A. G., Corradetti, R., Lowry, C. A. & Lesch, K-P., 24 Apr 2019, In : Frontiers in Neuroscience. 13, 12 p., 245.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The DNA methylome in panic disorder: a case-control and longitudinal psychotherapy-epigenetic study

Ziegler, C., Grundner-Culemann, F., Schiele, M. A., Schlosser, P., Kollert, L., Mahr, M., Gajewska, A., Lesch, K-P., Deckert, J., Koettgen, A. & Domschke, K., 21 Nov 2019, In : Translational Psychiatry. 9, 11 p., 314.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis

Gruenblatt, E., Nemoda, Z., Werling, A. M., Roth, A., Angyal, N., Tarnok, Z., Thomsen, H., Peters, T., Hinney, A., Hebebrand, J., Lesch, K-P., Romanos, M. & Walitza, S., Sep 2019, In : American Journal of Medical Genetics Part B-neuropsychiatric Genetics. 180, 6, p. 365-376 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Thiamine and benfotiamine counteract ultrasound-induced aggression, normalize AMPA receptor expression and plasticity markers, and reduce oxidative stress in mice

Gorlova, A., Pavlov, D., Anthony, D. C., Ponomarev, E. D., Sambon, M., Proshin, A., Shafarevich, I., Babaevskaya, D., Lesch, K-P., Bettendorff, L. & Strekalova, T., 15 Sep 2019, In : Neuropharmacology. 156, 18 p., 107543.

Research output: Contribution to journalArticleAcademicpeer-review

Transcript Analysis of Zebrafish GLUT3 Genes, slc2a3a and slc2a3b, Define Overlapping as Well as Distinct Expression Domains in the Zebrafish (Danio rerio) Central Nervous System

Lechermeier, C. G., Zimmer, F., Luffe, T. M., Lesch, K-P., Romanos, M., Lillesaar, C. & Drepper, C., 27 Aug 2019, In : Frontiers in molecular neuroscience. 12, 17 p., 199.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Analysis of shared heritability in common disorders of the brain

Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., Malik, R., Patsopoulos, N. A., Ripke, S., Wei, Z., Yu, D., Lee, P. H., Turley, P., Grenier-Boley, B., Chouraki, V., Kamatani, Y., Berr, C. & 32 others, Letenneur, L., Hannequin, D., Amouyel, P., Boland, A., Deleuze, J-F., Duron, E., Vardarajan, B. N., Reitz, C., Goate, A. M., Huentelman, M. J., Kamboh, M. I., Larson, E. B., Rogaeva, E., St George-Hyslop, P., Hakonarson, H., Kukull, W. A., Farrer, L. A., Barnes, L. L., Beach, T. G., Demirci, F. Y., Head, E., Hulette, C. M., Jicha, G. A., Kauwe, J. S. K., Kaye, J. A., Leverenz, J. B., Levey, A. I., Lieberman, A. P., Pankratz, V. S., Poon, W. W., Lesch, K-P. & van Os, J., 22 Jun 2018, In : Science. 360, 6395, 13 p., 8757.

Research output: Contribution to journalArticleAcademicpeer-review

Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment

Auth, C. S., Weidner, M. T., Popp, S., Strekalova, T., Schmitt-Boehrer, A. G., van den Hove, D. L. A., Lesch, K-P. & Waider, J., Nov 2018, In : European Neuropsychopharmacology. 28, 11, p. 1270-1283 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes

Roy, A., Laas, K., Kurrikoff, T., Reif, A., Veidebaum, T., Lesch, K-P. & Harro, J., 30 Aug 2018, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 86, p. 45-51 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD

Schaefer, N., Friedrich, M., Jorgensen, M. E., Kollert, S., Koepsell, H., Wischmeyer, E., Lesch, K-P., Geiger, D. & Doering, F., 4 Oct 2018, In : PLOS ONE. 13, 10, 20 p., 0205109.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3

Jansch, C., Gunther, K., Waider, J., Ziegler, G. C., Forero, A., Kollert, S., Svirin, E., Puhringer, D., Kwok, C. K., Ullmann, R., Maierhofer, A., Flunkert, J., Haaf, T., Edenhofer, F. & Lesch, K-P., 1 Apr 2018, In : Stem Cell Research. 28, p. 136-140 5 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Genetic variation in serotonin function impacts on altruistic punishment in the ultimatum game: A longitudinal approach

Gartner, A., Strobel, A., Reif, A., Lesch, K-P. & Enge, S., 1 Aug 2018, In : Brain and Cognition. 125, p. 37-44 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increased fear learning, spatial learning as well as neophobia in Rgs2(-/-) mice

Raab, A., Popp, S., Lesch, K-P., Lohse, M. J., Fischer, M., Deckert, J. & Hommers, L., 1 Apr 2018, In : Genes, Brain and Behavior. 17, 4, p. 1-14 14 p., e12420.

Research output: Contribution to journalArticleAcademicpeer-review

Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment

Pomytkin, I., Costa-Nunes, J. P., Kasatkin, V., Veniaminova, E., Demchenko, A., Lyundup, A., Lesch, K-P., Ponomarev, E. D. & Strekalova, T., 1 Sep 2018, In : CNS Neuroscience & Therapeutics. 24, 9, p. 763-774 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan

Franke, B., Michelini, G., Asherson, P., Banaschewski, T., Bilbow, A., Buitelaar, J. K., Cormand, B., Faraone, S. V., Ginsberg, Y., Haavik, J., Kuntsi, J., Larsson, H., Lesch, K-P., Antoni Ramos-Quiroga, J., Rethelyi, J. M., Ribases, M. & Reif, A., Oct 2018, In : European Neuropsychopharmacology. 28, 10, p. 1059-1088 30 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

Rutten, B. P. F., Vermetten, E., Vinkers, C. H., Ursini, G., Daskalakis, N. P., Pishva, E., Nijs, L., Houtepen, L. C., Eijssen, L., Jaffe, A. E., Kenis, G., Viechtbauer, W., den Hove, D., Schraut, K. G., Lesch, K-P., Kleinman, J. E., Hyde, T. M., Weinberger, D. R., Schalkwyk, L., Lunnon, K. & 8 others, Mill, J., Cohen, H., Yehuda, R., Baker, D. G., Maihofer, A. X., Nievergelt, C. M., Geuze, E. & Boks, M. P. M., 1 May 2018, In : Molecular Psychiatry. 23, 5, p. 1145-1156 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

OCD-like behavior is caused by dysfunction of thalamo-amygdala circuits and upregulated TrkB/ERK-MAPK signaling as a result of SPRED2 deficiency

Ullrich, M., Weber, M., Post, A. M., Popp, S., Grein, J., Zechner, M., Gonzalez, H. G., Kreis, A., Schmitt, A. G., Uceyler, N., Lesch, K-P. & Schuh, K., 1 Feb 2018, In : Molecular Psychiatry. 23, 2, p. 444-458 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pro-neurogenic, Memory-Enhancing and Anti-stress Effects of DF302, a Novel Fluorine Gamma-Carboline Derivative with Multi-target Mechanism of Action

Strekalova, T., Bahzenova, N., Trofimov, A., Schmitt-Bohrer, A. G., Markova, N., Grigoriev, V., Zamoyski, V., Serkova, T., Redkozubova, O., Vinogradova, D., Umriukhin, A., Fisenko, V., Lillesaar, C., Shevtsova, E., Sokolov, V., Aksinenko, A., Lesch, K-P. & Bachurin, S., 1 Jan 2018, In : Molecular Neurobiology. 55, 1, p. 335-349 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Autism-Like Behaviours and Memory Deficits Result from a Western Diet in Mice

Veniaminova, E., Cespuglio, R., Cheung, C. W., Umriukhin, A., Markova, N., Shevtsova, E., Lesch, K-P., Anthony, D. C. & Strekalova, T., 2017, In : Neural Plasticity. 2017, 14 p., 9498247.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain

Forero, A., Rivero, O., Waeldchen, S., Ku, H-P., Kiser, D. P., Gaertner, Y., Pennington, L. S., Waider, J., Gaspar, P., Jansch, C., Edenhofer, F., Resink, T. J., Blum, R., Sauer, M. & Lesch, K-P., 26 Sep 2017, In : Frontiers in Cellular Neuroscience. 11, 16 p., 307.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Elucidating the functions of brain GSK3-alpha: Possible synergy with GSK3-beta upregulation and reversal by antidepressant treatment in a mouse model of depressive-like behaviour

Pavlov, D., Markova, N., Bettendorff, L., Chekhonin, V., Pomytkin, I., Lioudyno, V., Svistunov, A., Ponomarev, E., Lesch, K-P. & Strekalova, T., 29 Sep 2017, In : Behavioural Brain Research. 335, p. 122-127 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice

Waider, J., Popp, S., Lange, M. D., Kern, R., Kolter, J. F., Kobler, J., Donner, N. C., Lowe, K. R., Malzbender, J. H., Brazell, C. J., Arnold, M. R., Aboagye, B., Schmitt-Boehrer, A., Lowry, C. A., Pape, H. C. & Lesch, K. P., 3 Oct 2017, In : Translational Psychiatry. 7, 9 p., 1246.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex

Guadalupe, T., Mathias, S. R., Vanerp, T. G. M., Whelan, C. D., Zwiers, M. P., Abe, Y., Abramovic, L., Agartz, I., Andreassen, O. A., Arias-Vasquez, A., Aribisala, B. S., Armstrong, N. J., Arolt, V., Artiges, E., Ayesa-Arriola, R., Baboyan, V. G., Banaschewski, T., Barker, G., Bastin, M. E., Baune, B. T. & 141 others, Blangero, J., Bokde, A. L. . W., Boedhoe, P. S. . W., Bose, A., Brem, S., Brodaty, H., Bromberg, U., Brooks, S., Buechel, C., Buitelaar, J., Calhoun, V. D., Cannon, D. M., Cattrell, A., Cheng, Y., Conrod, P. J., Conzelmann, A., Corvin, A., Crespo-Facorro, B., Crivello, F., Dannlowski, U., De Zubicaray, G. I., De Zwarte, S. M. C., Deary, I. J., Desrivieres, S., Doan, N. T., Donohoe, G., Dorum, E. S., Ehrlich, S., Espeseth, T., Fernandez, G., Flor, H., Fouche, J-P., Frouin, V., Fukunaga, M., Gallinat, J., Garavan, H., Gill, M., Suarez, A. G., Gowland, P., Grabe, H. J., Grotegerd, D., Gruber, O., Hagenaars, S., Hashimoto, R., Hauser, T. U., Heinz, A., Hibar, D. P., Hoekstra, P. J., Hoogman, M., Howells, F. M., Hu, H., Pol, H. E. H., Huyser, C., Ittermann, B., Jahanshad, N., Jonsson, E. G., Jurk, S., Kahn, R. S., Kelly, S., Kraemer, B., Kugel, H., Kwon, J. S., Lemaitre, H., Lesch, K-P., Lochner, C., Luciano, M., Marquand, A. F., Martin, N. G., Martinez-Zalacain, I., Martinot, J-L., Mataix-Cols, D., Mather, K., McDonald, C., McMahon, K. L., Medland, S. E., Menchon, J. M., Morris, D. W., Mothersill, O., Maniega, S. M., Mwangi, B., Nakamae, T., Nakao, T., Narayanaswaamy, J. C., Nees, F., Nordvik, J. E., Onnink, A. M. H., Opel, N., Ophoff, R., Martinot, M-L. P., Orfanos, D. P., Pauli, P., Paus, T., Poustka, L., Reddy, J. Y. C., Renteria, M. E., Roiz-Santianez, R., Roos, A., Royle, N. A., Sachdev, P., Sanchez-Juan, P., Schmaal, L., Schumann, G., Shumskaya, E., Smolka, M. N., Soares, J. C., Soriano-Mas, C., Stein, D. J., Strike, L. T., Toro, R., Turner, J. A., Tzourio-Mazoyer, N., Uhlmann, A., Hernandez, M. V., Van den Heuvel, O. A., Van der Meer, D., Van Haren, N. E. M., Veltman, D. J., Venkatasubramanian, G., Vetter, N. C., Vuletic, D., Walitza, S., Walter, H., Walton, E., Wang, Z., Wardlaw, J., Wen, W., Westlye, L. T., Whelan, R., Wittfeld, K., Wolfers, T., Wright, M. J., Xu, J., Xu, X., Yun, J-Y., Zhao, J., Franke, B., Thompson, P. M., Glahn, D. C., Mazoyer, B., Fisher, S. E. & Francks, C., Oct 2017, In : Brain Imaging and Behavior. 11, 5, p. 1497-1514 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Impact of varying social experiences during life history on behaviour, gene expression, and vasopressin receptor gene methylation in mice

Bodden, C., van den Hove, D., Lesch, K-P. & Sachser, N., 18 Aug 2017, In : Scientific Reports. 7, 10 p., 8719.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Increased functional coupling of 5-HT1A autoreceptors to GIRK channels in Tph2-/- mice

Mlinar, B., Montalbano, A., Waider, J., Lesch, K-P. & Corradetti, R., Dec 2017, In : European Neuropsychopharmacology. 27, 12, p. 1258-1267 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Postnatal LPS Challenge Impacts Escape Learning and Expression of Plasticity Factors Mmp9 and Timp1 in Rats: Effects of Repeated Training

Trofimov, A., Strekalova, T., Mortimer, N., Zubareva, O., Schwarz, A., Svirin, E., Umriukhin, A., Svistunov, A., Lesch, K-P. & Klimenko, V., Aug 2017, In : Neurotoxicity Research. 32, 2, p. 175-186 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Rsk2 Knockout Affects Emotional Behavior in the IntelliCage

Fischer, M., Cabello, V., Popp, S., Krackow, S., Hommers, L., Deckert, J., Lesch, K-P. & Schmitt-Boehrer, A. G., Jul 2017, In : Behavior Genetics. 47, 4, p. 434-448 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

SLC2A3 single-nucleotide polymorphism and duplication influence cognitive processing and population-specific risk for attention-deficit/hyperactivity disorder

Merker, S., Reif, A., Ziegler, G. C., Weber, H., Mayer, U., Ehlis, A-C., Conzelmann, A., Johansson, S., Mueller-Reible, C., Nanda, I., Haaf, T., Ullmann, R., Romanos, M., Fallgatter, A. J., Pauli, P., Strekalova, T., Jansch, C., Vasquez, A. A., Haavik, J., Ribases, M. & 4 others, Antoni Ramos-Quiroga, J., Buitelaar, J. K., Franke, B. & Lesch, K-P., Jul 2017, In : Journal of Child Psychology and Psychiatry. 58, 7, p. 798-809 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis

Hoogman, M., Bralten, J., Hibar, D. P., Mennes, M., Zwiers, M. P., Schweren, L. S. J., van Hulzen, K. J. E., Medland, S. E., Shumskaya, E., Jahanshad, N., de Zeeuw, P., Szekely, E., Sudre, G., Wolfers, T., Onnink, A. M. H., Dammers, J. T., Mostert, J. C., Vives-Gilabert, Y., Kohls, G., Oberwelland, E. & 62 others, Seitz, J., Schulte-Ruether, M., Ambrosino, S., Doyle, A. E., Hovik, M. F., Dramsdahl, M., Tamm, L., van Erp, T. G. M., Dale, A., Schork, A., Conzelmann, A., Zierhut, K., Baur, R., McCarthy, H., Yoncheva, Y. N., Cubillo, A., Chantiluke, K., Mehta, M. A., Paloyelis, Y., Hohmann, S., Baumeister, S., Bramati, I., Mattos, P., Tovar-Moll, F., Douglas, P., Banaschewski, T., Brandeis, D., Kuntsi, J., Asherson, P., Rubia, K., Kelly, C., Di Martino, A., Milham, M. P., Castellanos, F. X., Frodl, T., Zentis, M., Lesch, K-P., Reif, A., Pauli, P., Jernigan, T. L., Haavik, J., Plessen, K. J., Lundervold, A. J., Hugdahl, K., Seidman, L. J., Biederman, J., Rommelse, N., Heslenfeld, D. J., Hartman, C. A., Hoekstra, P. J., Oosterlaan, J., von Polier, G., Konrad, K., Vilarroya, O., Antoni Ramos-Quiroga, J., Carles Soliva, J., Durston, S., Buitelaar, J. K., Faraone, S. V., Shaw, P., Thompson, P. M. & Franke, B., Apr 2017, In : Lancet Psychiatry. 4, 4, p. 310-319 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation

Kyriakakis, E., Frismantiene, A., Dasen, B., Pfaff, D., Rivero, O., Lesch, K-P., Erne, P., Resink, T. J. & Philippova, M., Jul 2017, In : Cellular Signalling. 35, p. 163-175 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Thiamine and benfotiamine improve cognition and ameliorate GSK-3β-associated stress-induced behaviours in mice

Markova, N., Bazhenova, N., Anthony, D. C., Vignisse, J., Svistunov, A., Lesch, K-P., Bettendorff, L. & Strekalova, T., 3 Apr 2017, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 75, p. 148-156 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016
2 Citations (Scopus)

CO2 exposure as translational cross-species experimental model for panic

Leibold, N. K., van den Hove, D. L. A., Viechtbauer, W., Buchanan, G. F., Goossens, L., Lange, I., Knuts, I., Lesch, K. P., Steinbusch, H. W. M. & Schruers, K. R. J., 6 Sep 2016, In : Translational Psychiatry. 6, e885.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Genome-Wide Analyses of Aggressiveness in Attention-Deficit Hyperactivity Disorder

Brevik, E. J., van Donkelaar, M. M. J., Weber, H., Sanchez-Mora, C., Jacob, C., Rivero, O., Kittel-Schneider, S., Garcia-Martinez, I., Aebi, M., van Hulzen, K., Cormand, B., Ramos-Quiroga, J. A., Lesch, K-P., Reif, A., Ribases, M., Franke, B., Posserud, M-B., Johansson, S., Lundervold, A. J., Haavik, J. & 1 others, Zayats, T., Jul 2016, In : American Journal of Medical Genetics Part B-neuropsychiatric Genetics. 171, 5, p. 733-747

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test

Strekalova, T., Markova, N., Shevtsova, E., Zubareva, O., Bakhmet, A., Steinbusch, H. M., Bachurin, S. & Lesch, K-P., 2016, In : Neural Plasticity. 2016, 5098591.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice

Strekalova, T., Costa-Nunes, J. P., Veniaminova, E., Kubatiev, A., Lesch, K-P., Chekhonin, V. P., Evans, M. C. & Steinbusch, H. W. M., 15 May 2016, In : Journal of Affective Disorders. 196, p. 109-116

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

Couch, Y., Trofimov, A., Markova, N., Nikolenko, V., Steinbusch, H. W., Chekhonin, V., Schroeter, C., Lesch, K-P., Anthony, D. C. & Strekalova, T., 16 May 2016, In : Journal of Neuroinflammation. 13, 108.

Research output: Contribution to journalArticleAcademicpeer-review

Ultrasound of alternating frequencies and variable emotional impact evokes depressive syndrome in mice and rats

Morozova, A., Zubkov, E., Strekalova, T., Kekelidze, Z., Storozeva, Z., Schroeter, C. A., Bazhenova, N., Lesch, K-P., Cline, B. H. & Chekhonin, V., 4 Jul 2016, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 68, p. 52-63

Research output: Contribution to journalArticleAcademicpeer-review