20102018
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Research Output 2010 2018

2018

EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition

Jutten, B., Keulers, T. G., Peeters, H. J. M., Schaaf, M. B. E., Savelkouls, K. G. M., Compter, I., Clarijs, R., Schijns, O. E. M. G., Ackermans, L., Teernstra, O. P. M., Zonneveld, M. I., Colaris, R. M. E., Dubois, L., Vooijs, M. A., Bussink, J., Sotelo, J., Theys, J., Lammering, G. & Rouschop, K. M. A., 1 Jan 2018, In : Autophagy. 14, 2, p. 283-295 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015
5 Citations (Scopus)

Canonical autophagy does not contribute to cellular radioresistance

Schaaf, M. B., Jutten, B., Keulers, T. G., Savelkouls, K. G., Peeters, H. J., van den Beucken, T., van Schooten, F. J., Godschalk, R. W., Vooijs, M. & Rouschop, K. M., Mar 2015, In : Radiotherapy and Oncology. 114, 3, p. 406-412 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

GABARAPL1 is required for increased EGFR membrane expression during hypoxia

Keulers, T. G., Schaaf, M. B. E., Peeters, H. J. M., Savelkouls, K. G. M., Vooijs, M. A., Bussink, J., Jutten, B. & Rouschop, K. M. A., Sep 2015, In : Radiotherapy and Oncology. 116, 3, p. 417-422

Research output: Contribution to journalArticleAcademicpeer-review

2013
8 Citations (Scopus)

EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival

Jutten, B., Keulers, T. G., Schaaf, M. B. E., Savelkouls, K., Theys, J., Span, P. N., Vooijs, M. A., Bussink, J. & Rouschop, K. M. A., Sep 2013, In : Radiotherapy and Oncology. 108, 3, p. 479-483

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia

Schaaf, M. B. E., Cojocari, D., Keulers, T. G., Jutten, B., Starmans, M. H., de Jong, M. C., Begg, A. C., Savelkouls, K. G. M., Bussink, J., Vooijs, M., Wouters, B. G. & Rouschop, K. M. A., Sep 2013, In : Radiotherapy and Oncology. 108, 3, p. 529-534

Research output: Contribution to journalArticleAcademicpeer-review

2011

Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction

Rouschop, K. M. A., Dubois, L., Schaaf, M. B. E., van den Beucken, T., Lieuwes, N., Keulers, T. G. H., Savelkouls, K. G. M., Bussink, J., van der Kogel, A. J., Koritzinsky, M. & Wouters, B. G., Jun 2011, In : Radiotherapy and Oncology. 99, 3, p. 385-391

Research output: Contribution to journalArticleAcademicpeer-review

2010

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

Rouschop, K. M. A., van den Beucken, T., Dubois, L., Niessen, H., Bussink, J., Savelkouls, K., Keulers, T., Mujcic, H., Landuyt, W., Voncken, J. W., Lambin, P., van der Kogel, A. J., Koritzinsky, M. & Wouters, B. G., Jan 2010, In : Journal of Clinical Investigation. 120, 1, p. 127-141

Research output: Contribution to journalArticleAcademicpeer-review