20052020

Research output per year

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Research Output

2005

Experimental studies on the effects of licit and illicit drugs on driving performance, psychomotor skills and cognitive function

Ramaekers, J. G., Kuypers, K. P., Wood, C. M., Hockey, C. R. J., Samson, S., Jamson, H. & Birch, E., 1 Jan 2005, Brussels: European Commission. 92 p.

Research output: Book/ReportReportProfessional

Transient memory impairment after acute dose of 75mg 34-Methylene-dioxymethamphetamine.

Kuypers, K. P. C. & Ramaekers, J. G., 1 Jan 2005, In : Journal of Psychopharmacology. 19, 6, p. 633-639

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)
2006
11 Citations (Scopus)
65 Citations (Scopus)

MDMA and alcohol effects, combined and alone, on objective and subjective measures of actual driving performance and psychomotor function

Kuypers, K. P. C., Samyn, N. & Ramaekers, J. G., 1 Jan 2006, In : Psychopharmacology. 187, p. 467-475

Research output: Contribution to journalArticleAcademicpeer-review

56 Citations (Scopus)

Performance and behavioral effects of illicit drugs

Schmitt, J. A. J., Lamers, C. T. J., Kuypers, K. P. C., Ramaekers, J. G. & Riedel, W. J., 1 Jan 2006, Medical legal aspects of drugs. Burns, M. (ed.). Tucson: Lawyers & Judges, p. 71-90

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Stimulant effects of 3,4-methylenedioxymethamphetamine (MDMA) 75 mg and methylphenidate 20 mg on actual driving during intoxication and withdrawal

Ramaekers, J. G., Kuypers, K. P. C. & Samyn, N., 1 Jan 2006, In : Addiction. 101, p. 1614-21

Research output: Contribution to journalArticleAcademicpeer-review

48 Citations (Scopus)
2007

Acute dose of MDMA (75 mg) impairs spatial memory for location but leaves contextual processing of visuospatial information unaffected

Kuypers, K. P. & Ramaekers, J. G., 1 Jan 2007, In : Psychopharmacology. 189, 4, p. 557-563

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Acute effects of nocturnal doses of MDMA on measures of impulsivity and psychomotor performance throughout the night

Kuypers, K. P., Wingen, M., Samyn, N., Limbert, N. & Ramaekers, J. G., 1 Jan 2007, In : Psychopharmacology. 192, 1, p. 111-119

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Psychedelic bliss : memory and risk taking during MDMA intoxication

Kuypers, K. P. C., 1 Jan 2007, Maastricht: Universiteit Maastricht. 179 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
328 Downloads (Pure)

Selective verbal and spatial memory impairment after 5-HT1A and 5-HT2A receptor blockade in healthy volunteers pre-treated with an SSRI

Wingen, M., Kuypers, K. P. C. & Ramaekers, J. G., 1 Jan 2007, In : Journal of Psychopharmacology. 21, 5, p. 477-485

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

The role of 5-HT(1a) and 5-HT (2a) receptors in attention and motor control: a mechanistic study in healthy volunteers

Wingen, M., Kuypers, K. P. C. & Ramaekers, J. G., 1 Jan 2007, In : Psychopharmacology. 190, 3, p. 391-400

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)
2008

Memory and mood during the night and in the morning after repeated evening doses of MDMA

Kuypers, K. P. C., Wingen, M. & Ramaekers, J. G., 1 Jan 2008, In : Journal of Psychopharmacology. 22, 8, p. 895-903

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Sustained attention and serotonin: a pharmaco-fMRI study

Wingen, M., Kuypers, K. P. C., van de Ven, V. G., Formisano, E. & Ramaekers, J. G., 1 Jan 2008, In : Human Psychopharmacology-Clinical and Experimental. 23, 3, p. 221-230

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)
2009

Ecstasy, driving and traffic safety

Kuypers, K. P. C., Bosker, W. M. & Ramaekers, J. G., 1 Jan 2009, Drug, driving and traffic safety. Basel: Birkhauser Verlag, p. 501-550

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

3 Citations (Scopus)

Involvement of inferior parietal lobules in prospective memory impairment during acute MDMA (ecstasy) intoxication: an event-related fMRI study

Ramaekers, J. G., Kuypers, K. P. C., Wingen, M., Heinecke, A. & Formisano, E., 1 Jan 2009, In : Neuropsychopharmacology. 34, 7, p. 1641-1648

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)
2010

Dose-related effects of MDMA on psychomotor function and mood before, during, and after a night of sleep loss

Bosker, W. M., Kuypers, K. P. C., Conen, S. & Ramaekers, J. G., Mar 2010, In : Psychopharmacology. 209, 1, p. 69-76 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Psychofarmaca en rijvaardigheid

Vermeeren, A., Wolschrijn, H., Leufkens, T. R. M., Theunissen, E. L., Kuypers, K. P. C. & Ramaekers, J. G., 1 Jan 2010, In : Psyfar. 2, 2, p. 62-65

Research output: Contribution to journalArticleProfessional

2011

Blockade of 5-HT(2) receptor selectively prevents MDMA-induced verbal memory impairment

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Bosker, W. M., Bakker, K. & Ramaekers, J. G., 1 Jan 2011, In : Neuropsychopharmacology. 36, 9, p. 1932-1939

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)

MDMA intoxication and verbal memory performance: a placebo-controlled pharmaco-MRI study

Kuypers, K. P. C., Wingen, M., Heinecke, A., Formisano, E. & Ramaekers, J. G., 1 Jan 2011, In : Journal of Psychopharmacology. 25, 8, p. 1053-1061

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
2012

A case-control study estimating accident risk for alcohol, medicines and illegal drugs

Kuypers, K. P. C., Legrand, S. A., Ramaekers, J. G. & Verstraete, A. G., 28 Aug 2012, In : PLOS ONE. 7, 8, 9 p., e43496.

Research output: Contribution to journalArticleAcademicpeer-review

36 Citations (Scopus)

A placebo-controlled study to assess Standardized Field Sobriety Tests performance during alcohol and cannabis intoxication in heavy cannabis users and accuracy of point of collection testing devices for detecting THC in oral fluid

Bosker, W. M., Theunissen, E. L., Conen, S., Kuypers, K. P. C., Jeffery, W. K., Walls, H. C., Kauert, G. F., Toennes, S. W., Moeller, M. R. & Ramaekers, J. G., Oct 2012, In : Psychopharmacology. 223, 4, p. 439-446 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT(2) and 5-HT(1) receptors

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Bosker, W. M., Bakker, K. & Ramaekers, J. G., 10 Jul 2012, In : PLOS ONE. 7, 7, 8 p., 40187.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
20 Citations (Scopus)

Effects of stimulant drugs on actual and simulated driving: perspectives from four experimental studies conducted as part of the DRUID research consortium.

Ramaekers, J. G., Kuypers, K. P. C., Bosker, W. M., Brookhuis, K. A., Veldstra, J. A., Simons, R., Martens, M., Hjalmdahl, M., Forsman, A. & Knoche, A., 1 Jan 2012, In : Psychopharmacology. 222, 3, p. 413-418

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral fluid

Bosker, W. M., Kuypers, K. P. C., Conen, S., Kauert, G. F., Toennes, S. W., Skopp, G. & Ramaekers, J. G., Aug 2012, In : Psychopharmacology. 222, 3, p. 367-376 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Medicinal Delta(9)-tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests

Bosker, W. M., Kuypers, K. P. C., Theunissen, E. L., Surinx, A., Blankespoor, R. J., Skopp, G., Jeffery, W. K., Walls, H. C., van Leeuwen, C. J. & Ramaekers, J. G., Oct 2012, In : Addiction. 107, 10, p. 1837-1844 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
2013

Escitalopram Decreases Cross-Regional Functional Connectivity within the Default-Mode Network

van de Ven, V., Wingen, M., Kuypers, K. P. C., Ramaekers, J. G. & Formisano, E., 27 Jun 2013, In : PLOS ONE. 8, 6, 10 p., 68355.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
16 Citations (Scopus)

Inhibition of MDMA-induced increase in cortisol does not prevent acute impairment of verbal memory

Kuypers, K. P. C., de la Torre, R., Farre, M., Pujadas, M. & Ramaekers, J. G., 1 Jan 2013, In : British Journal of Pharmacology. 168, 3, p. 607-617

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Methylphenidate reduces functional connectivity of nucleus accumbens in brain reward circuit

Ramaekers, J. G., Evers, E. A., Theunissen, E. L., Kuypers, K. P. C., Goulas, A. & Stiers, P., Sep 2013, In : Psychopharmacology. 229, 2, p. 219-226 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Psychomotor function in chronic daily Cannabis smokers during sustained abstinence

Bosker, W. M., Karschner, E. L., Lee, D., Goodwin, R. S., Hirvonen, J., Innis, R. B., Theunissen, E. L., Kuypers, K. P. C., Huestis, M. A. & Ramaekers, J. G., 2 Jan 2013, In : PLOS ONE. 8, 1, 7 p., 53127.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
25 Citations (Scopus)

Single doses of THC and cocaine decrease proficiency of impulse control in heavy cannabis users

van Wel, J. H. P., Kuypers, K. P. C., Theunissen, E. L., Toennes, S. W., Spronk, D. B., Verkes, R. J. & Ramaekers, J. G., Dec 2013, In : British Journal of Pharmacology. 170, 7, p. 1410-1420 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
2014

Memory and mood during MDMA intoxication, with and without memantine pretreatment

de Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Heckman, P., de la Torre, R., Farre, M. & Ramaekers, J. G., Dec 2014, In : Neuropharmacology. 87, p. 198-205 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

No evidence that MDMA-induced enhancement of emotional empathy is related to peripheral oxytocin levels or 5-HT1a receptor activation

Kuypers, K. P. C., de la Torre, R., Farre, M., Yubero-Lahoz, S., Dziobek, I., Bos, W. & Ramaekers, J. G., 27 Jun 2014, In : PLOS ONE. 9, 6, 14 p., e100719.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)
2015

Cannabis and cocaine decrease cognitive impulse control and functional corticostriatal connectivity in drug users with low activity DBH genotypes

Ramaekers, J. G., van Wel, J. H., Spronk, D., Franke, B., Kenis, G., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L., Stiers, P. & Verkes, R. J., 14 Dec 2015, In : Brain Imaging and Behavior. p. 1254–1263

Research output: Contribution to journalArticleAcademicpeer-review

Changes in serotonin transporter (5-HTT) gene expression in peripheral blood cells after MDMA intake

Yubero-Lahoz, S., Kuypers, K. P. C., Ramaekers, J. G., Langohr, K., Farre, M. & de la Torre, R., Jun 2015, In : Psychopharmacology. 232, 11, p. 1921-1929

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Emotion recognition during cocaine intoxication

Kuypers, K., Steenbergen, L., Theunissen, E., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2015, p. S213-S213.

Research output: Contribution to conferencePosterAcademic

MDMA, cannabis, and cocaine produce acute dissociative symptoms

van Heugten-Van der Kloet, D., Giesbrecht, T., van Wel, J., Bosker, W. M., Kuypers, K. P. C., Theunissen, E. L., Spronk, D. B., Verkes, R. J., Merckelbach, H. & Ramaekers, J. G., 30 Aug 2015, In : Psychiatry Research. 228, 3, p. 907-912 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Psychedelic symptoms of cannabis and cocaine use as a function of trait impulsivity

van Wel, J. H. P., Spronk, D. B., Kuypers, K. P. C., Theunissen, E. L., Toennes, S. W., Verkes, R. J. & Ramaekers, J. G., 1 Mar 2015, In : Journal of Psychopharmacology. 29, 3, p. 324-334 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Rivastigmine but not vardenafil reverses cannabis-induced impairment of verbal memory in healthy humans

Theunissen, E. L., Heckman, P., de Sousa Fernandes Perna, E. B., Kuypers, K. P. C., Sambeth, A., Blokland, A., Prickaerts, J., Toennes, S. W. & Ramaekers, J. G., 1 Jan 2015, In : Psychopharmacology. 232, 2, p. 343-353 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
2016

Amphetamine & methamphetamine: pharmacokinetics and pharmacodynamics

Kuypers, K. P. C., Theunissen, E. L. & Ramaekers, J. G., 18 Oct 2016, The SAGE handbook of drug and alcohol studies: Biological approaches. Wolff, K., White, J. & Karch, S. (eds.). SAGE, p. 131-151

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Ayahuasca enhances creative divergent thinking while decreasing conventional convergent thinking

Kuypers, K. P. C., Riba, J., de la Fuente Revenga, M., Barker, S., Theunissen, E. L. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3395–3403 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
164 Downloads (Pure)

Cannabis and tolerance: acute drug impairment as a function of cannabis use history

Ramaekers, J. G., van Wel, J. H., Spronk, D. B., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L. & Verkes, R. J., 26 May 2016, In : Scientific Reports. 6, 8 p., 26843.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
159 Downloads (Pure)

Cannabis and tolerance: acute drug impairment as a function of cannabis use history

Ramaekers, J. G., van Wel, J. H., Spronk, D. B., Toennes, S. W., Kuypers, K. P. C., Theunissen, E. L. & Verkes, R. J., 2 Sep 2016, In : Scientific Reports. 6, 1 p., 31939.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access
File
104 Downloads (Pure)

MEPHEDRONE EFFECTS ON ACUTE ALCOHOL INTOXICATION

Papaseit, E., Perez-Mana, C., de Souza, E., Mateus, J. A., Olesti, E., Theunissen, E., Kuypers, K., Ramaekers, J., Fonseca, F., Torrens, M., de la Torre, R. & Farre, M., Oct 2016, p. 28-28. 1 p.

Research output: Contribution to conferenceAbstractAcademic

Neurocognitive performance following acute mephedrone administration, with and without alcohol

de Sousa Fernandes Perna, E. B., Papaseit, E., Pérez-Mañá, C., Mateus, J., Theunissen, E. L., Kuypers, K. P. C., de la Torre, R., Farré, M. & Ramaekers, J. G., Dec 2016, In : Journal of Psychopharmacology. 30, 12, p. 1305–1312 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

P.6.f.004 - Ayahuasca enhances creative divergent thinking

Kuypers, K. P. C., Riba, J., De la Fuente Revenga, M., Barker, S., Theunissen, E. L. & Ramaekers, J. G., Oct 2016, In : European Neuropsychopharmacology. 26, Supplement 2, p. S705-S706 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

1 Citation (Scopus)

Subjective aggression during alcohol and cannabis intoxication before and after aggression exposure

De Sousa Fernandes Perna, E. B., Theunissen, E. L., Kuypers, K. P. C., Toennes, S. W. & Ramaekers, J. G., Sep 2016, In : Psychopharmacology. 233, 18, p. 3331–3340 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2 Citations (Scopus)
147 Downloads (Pure)

Verbal memory impairment in polydrug ecstasy users: A clinical perspective

Kuypers, K. P. C., Theunissen, E. L., van Wel, J. H. P., de Sousa, E. B., Perna, F., Linssen, A., Sambeth, A., Schultz, B. G. & Ramaekers, J. G., 23 Feb 2016, In : PLOS ONE. 11, 2, 0149438.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)
143 Downloads (Pure)