19952020

Research output per year

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Research Output

Review article
Open Access

From OPC to Oligodendrocyte: An Epigenetic Journey

Tiane, A., Schepers, M., Rombaut, B., Hupperts, R., Prickaerts, J., Hellings, N., van den Hove, D. & Vanmierlo, T., Oct 2019, In : Cells. 8, 10, 19 p., 1236.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Mechanism of acute tryptophan depletion: is it only serotonin?

van Donkelaar, E. L., Blokland, A., Ferrington, L., Kelly, P. A., Steinbusch, H. W. M. & Prickaerts, J., Jul 2011, In : Molecular Psychiatry. 16, 7, p. 695-713 19 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Phosphodiesterase inhibition and modulation of corticostriatal and hippocampal circuits: Clinical overview and translational considerations

Heckman, P. R. A., Blokland, A., Bollen, E. P. P. & Prickaerts, J., Apr 2018, In : Neuroscience and Biobehavioral Reviews. 87, p. 233-254 22 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Phosphodiesterase Type 4 Inhibition in CNS Diseases

Blokland, A., Heckman, P., Vanmierlo, T., Schreiber, R., Paes, D. & Prickaerts, J., Dec 2019, In : Trends in Pharmacological Sciences. 40, 12, p. 971-985 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

Schepers, M., Tiane, A., Paes, D., Sanchez, S., Rombaut, B., Piccart, E., Rutten, B. P. F., Brone, B., Hellings, N., Prickaerts, J. & Vanmierlo, T., 24 Jul 2019, In : Frontiers in Immunology. 10, p. 1-17 17 p., 1727.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Poster

Effects of riociguat and biperiden on memory

Borghans, L. G. J. M., Sambeth, A., Prickaerts, J. H. H. J., Ramaekers, J. G. & Blokland, A., Oct 2017, p. S645-S645.

Research output: Contribution to conferencePosterAcademic

Inaugural speech

Neuropsychofarmacologie in Translatie

Prickaerts, J., 16 Nov 2018

Research output: Book/ReportInaugural speechPopular

Erratum / corrigendum

Publisher Correction: Assessing spatial pattern separation in rodents using the object pattern separation task

van Goethem, N. P., van Hagen, B. T. J. & Prickaerts, J., Jul 2019, In : Nature Protocols. 14, 7, p. 2259-2259 1 p.

Research output: Contribution to journalErratum / corrigendumAcademic

Doctoral Thesis
205 Downloads (Pure)
Conference Abstract/Poster in journal

The PDE4-inhibitor roflumilast improves memory: findings from a translational perspective

Van Duinen, M. A., Sambeth, A., Heckman, P. R. A., Tsai, M., Lahu, G., Uz, T., Blokland, A. & Prickaerts, J., Oct 2017, In : European Neuropsychopharmacology. 27, Suppl 4, p. S1024-S1025

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Chapter

Delivery of DNA into the central nervous system via electroporation

De Vry, J., Vanmierlo, T., Martínez-Martínez, P., Losen, M., Temel, Y., Steinbusch, H., De Baets, M. & Prickaerts, J., 2014, Methods in molecular biology. Vol. 1121. p. 157-63 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Effects of glucocorticoids on emotion and memory processes in animals

Prickaerts, J. H. H. J. & Steckler, T., 1 Jan 2005, Handbook of Stress and the Brain, Part 1: The Neurobiology of Stress. Steckler, T. & Kalin, N. H. (eds.). Amsterdam [etc.]: Elsevier, p. 359-386 (Techniques in the behavioral and neural sciences; No. 15).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Episodic memory and the medial temporal lobe: towards a unifying framework of recognition and recall

Berkers, R., van Goethem, N., Rutten, K., Blokland, A. & Prickaerts, J., 2015, Episodic Memory: Formation, Clinical Disorders and Role of Aging. . Edison, K. (ed.). New York: Nova Science Publishers, p. 85-134 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

From Age-Related Cognitive Decline to Alzheimer's Disease: A Translational Overview of the Potential Role for Phosphodiesterases

Heckman, P. R. A., Blokland, A. & Prickaerts, J., 2017, Phosphodiesterases: CNS Functions and Diseases. Zhang, H-T., Xu, Y. & O'Donnell, J. M. (eds.). Springer, p. 135-168 34 p. (Advances in Neurobiology, Vol. 17).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

From age-related cognitive decline to Alzheimer’s disease: a translational overview of the potential role for phosphodiesterases

Heckman, P., Blokland, A. & Prickaerts, J., 2017, Phosphodiesterases: CNS Functions and Diseases. . Zhang, H-T., Xu, Y. & O'Donnell, J. M. (eds.). Berlin: Springer Verlag, p. 217-221 4 p. (Advances in Neurobiology, Vol. 17).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Phosphodiesterase Inhibitors

Prickaerts, J., 2015, Encyclopedia of Psychopharmacology .

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

The Impact of Fluoxetine Treatment on BDNF Signaling and Cellular Plasticity in the Brain

de Vry, J., Boulle, F., Rutten, B., van den Hove, D. & Prickaerts, J., 2015, Fluoxetine: Pharmacology, Mechanisms of Action and Potential Side Effects .

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Article

7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice

Bollen, E., Vanmierlo, T., Akkerman, S., Wouters, C., Steinbusch, H. M. W. & Prickaerts, J., 15 Nov 2013, In : Behavioural Brain Research. 257, p. 8-12

Research output: Contribution to journalArticleAcademicpeer-review

Activation of 5-HT1A postsynaptic receptors by NLX-101 results in functional recovery and an increase in neuroplasticity in mice with brain ischemia

Aguiar, R. P., Soares, L. M., Meyer, E., da Silveira, F. C., Milani, H., Newman-Tancredi, A., Varney, M., Prickaerts, J. & Weffort Oliveira, R. M., 20 Apr 2020, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 99, 12 p., 109832.

Research output: Contribution to journalArticleAcademicpeer-review

Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults

Van Duinen, M. A., Sambeth, A., Heckman, P. R. A., Smit, S., Tsai, M., Lahu, G., Uz, T., Blokland, A. & Prickaerts, J., 15 Mar 2018, In : Neuropharmacology. 131, p. 31-38 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acute administration of roflumilast enhances sensory gating in healthy young humans in a randomized trial

Heckman, P. R. A., Van Duinen, M. A., Blokland, A., Uz, T., Prickaerts, J. & Sambeth, A., Jan 2018, In : Psychopharmacology. 235, 1, p. 301–308 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acute effects of acetyl-L-carnitine on sodium cyanide-induced behavioral and biochemical deficits

Prickaerts, J., Blokland, A., Bothmer, J., Honig, W., Markerink - van Ittersum, M. & Jolles, J., 1 Jan 1998, In : Neurochemistry International. 33, 5, p. 435-443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
13 Downloads (Pure)

Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals: a double-blind placebo-controlled study

Blokland, A., Van Duinen, M. A., Sambeth, A., Heckman, P. R. A., Tsai, M., Lahu, G., Uz, T. & Prickaerts, J., May 2019, In : Neurobiology of Aging. 77, p. 37-43 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acute tryptophan depletion in C57BL/6 mice does not induce central serotonin reduction or affective behavioural changes

van Donkelaar, E. L., Blokland, A., Lieben, C. K. J., Kenis, G. R. L., Ferrington, L., Kelly, P. A., Steinbusch, H. W. M. & Prickaerts, J., 1 Jan 2010, In : Neurochemistry International. 56, 1, p. 21-34 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Acute tryptophan depletion in rats alters the relationship between cerebral blood flow and glucose metabolism independent of central serotonin

van Donkelaar, E. L., Ferrington, L., Blokland, A., Steinbusch, H. W. M., Prickaerts, J. H. H. J. & Kelly, P. A., 1 Jan 2009, In : Neuroscience. 163, 2, p. 683-694

Research output: Contribution to journalArticleAcademicpeer-review

Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats

van Donkelaar, E. L., Kelly, P. A., Dawson, N., Blokland, A., Prickaerts, J., Steinbusch, H. W. M. & Ferrington, L., 15 May 2010, In : Journal of Neuroscience Research. 88, 7, p. 1557-1568 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Adrenalectomy and corticosterone replacement differentially alter CA3 dendritic morphology and new cell survival in the adult rat hippocampus

Martinez-Claros, M., Steinbusch, H. W. M., van Selm, A., van den Hove, D. L. A., Prickaerts, J. & Pawluski, J. L., Mar 2013, In : Journal of Chemical Neuroanatomy. 48-49, p. 23-28

Research output: Contribution to journalArticleAcademicpeer-review

Aging and focus switching in working memory: Excluding the potential role of memory load

van Gerven, P. W. M., Meijer, W. A., Prickaerts, J. H. H. J. & van der Veen, F. M., 1 Jan 2008, In : Experimental Aging Research. 34, 4, p. 367-378

Research output: Contribution to journalArticleAcademicpeer-review

Analysis of spatial orientation strategies of male and female Wistar rats in a Morris water escape task

Blokland, A., Rutten, K. & Prickaerts, J. H. H. J., 1 Jan 2006, In : Behavioural Brain Research. 171, p. 216-224

Research output: Contribution to journalArticleAcademicpeer-review

Antagonizing alpha 7 nicotinic receptors with methyllycaconitine (MLA) potentiates receptor activity and memory acquisition

van Goethem, N. P., Paes, D., Puzzo, D., Fedele, E., Rebosio, C., Gulisano, W., Palmeri, A., Wennogle, L. P., Peng, Y., Bertrand, D. & Prickaerts, J., Oct 2019, In : Cellular Signalling. 62, p. 1-8 8 p., 109338.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Apolipoprotein CI knock-out mice display impaired memory functions

Berbee, J. F., Vanmierlo, T., Abildayeva, K., Blokland, A., Jansen, P. J., Lütjohann, D., Gautier, T., Sijbrands, E., Prickaerts, J., Hadfoune, M. H., Ramaekers, F. C. S., Kuipers, F., Rensen, P. C. & Mulder, M., 1 Jan 2011, In : Journal of Alzheimer's Disease. 23, 4, p. 737-747 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Assessing spatial pattern separation in rodents using the object pattern separation task

van Goethem, N. P., van Hagen, B. T. J. & Prickaerts, J., 1 Aug 2018, In : Nature Protocols. 13, 8, p. 1763-1792 30 p.

Research output: Contribution to journalArticleAcademicpeer-review

Atypical cognitive profile in patients with depression after myocardial infarction.

Dijkstra, J. B., Strik, J. J. M. H., Lousberg, R., Prickaerts, J. H. H. J., Riedel, W. J., Jolles, J., van Praag, H. M. & Honig, A., 1 Jan 2002, In : Journal of Affective Disorders. 20, p. 181-190

Research output: Contribution to journalArticleAcademicpeer-review

Automated scoring of novel object recognition in rats

Rutten, K., Reneerkens, O. A. H., Hamers, H., Sik, A., McGregor, I. S., Prickaerts, J. H. H. J. & Blokland, A., 1 Jan 2008, In : Journal of Neuroscience Methods. 171, 1, p. 72-77

Research output: Contribution to journalArticleAcademicpeer-review

Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice

Sierksma, A. S. R., Prickaerts, J., Chouliaras, L., Rostamian, S., Delbroek, L., Rutten, B. P. F., Steinbusch, H. W. M. & van den Hove, D. L. A., Jan 2013, In : Neurobiology of Aging. 34, 1, p. 319-337

Research output: Contribution to journalArticleAcademicpeer-review

Brain enzyme activities after intracerebroventricular injection of streptozotocin in rats receiving acetyl-L-carnitine

Terwel, D., Prickaerts, J., Meng, F. & Jolles, J., 1 Jan 1995, In : European Journal of Pharmacology. 287, 1, p. 65-71 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
16 Downloads (Pure)

Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice

Vanmierlo, T., Rutten, K., van Vark - van der Zee, L. C., Friedrichs, S., Bloks, V. W., Blokland, A., Ramaekers, F. C., Sijbrands, E., Steinbusch, H., Prickaerts, J., Kuipers, F., Lütjohann, D. & Mulder, M., Jun 2011, In : Plant Foods for Human Nutrition. 66, 2, p. 149-156 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Changes in voiding behavior in a mouse model of Alzheimer's disease

Biallosterski, B. T., Prickaerts, J., Rahnama'i, M. S., de Wachter, S., van Koeveringe, G. A. & Meriaux, C., 25 Aug 2015, In : Frontiers in Aging Neuroscience. 7, 160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chronic corticosterone manipulations in mice affect brain cell proliferation rates, but only partly affect BDNF protein levels

Prickaerts, J. H. H. J., van den Hove, D. L. A., Fierens, F. L., Kia, H. K., Lenaerts, I. & Steckler, T., 1 Jan 2006, In : Neuroscience Letters. 396, p. 12-2007

Research output: Contribution to journalArticleAcademicpeer-review

Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time

Bus, B. A. A., Molendijk, M. L., Tendolkar, I., Penninx, B. W. J. H., Prickaerts, J., Elzinga, B. M. & Voshaar, R. C. O., May 2015, In : Molecular Psychiatry. 20, 5, p. 602-608

Research output: Contribution to journalArticleAcademicpeer-review

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Sierksma, A. S. R., Rutten, K., Sydlik, S., Rostamian, S., Steinbusch, H. W. M., van den Hove, D. L. A. & Prickaerts, J., Jan 2013, In : Neuropharmacology. 64, p. 124-136

Research output: Contribution to journalArticleAcademicpeer-review

Cognition- and anxiety-related behavior, synaptophysin and MAP2 immunoreactivity in the adult rat treated with a single course of antenatal betamethasone

Bruschettini, M., van den Hove, D. L. A., Timmers, S., Welling, M., Steinbusch, H. P. J., Prickaerts, J. H. H. J., Gazzolo, D., Blanco, C. E. & Steinbusch, H. W. M., 1 Jan 2006, In : Pediatric Research. 60, 1, p. 50-54

Research output: Contribution to journalArticleAcademicpeer-review

Continuous infusion of the alpha 7 nicotinic acetylcholine receptor agonist EVP-6124 produces no signs of tolerance at memory-enhancing doses in rats: a pharmacokinetic and behavioral study

van Goethem, N. P., Prickaerts, J., Welty, D., Flood, D. G. & Koenig, G., Jun 2015, In : Behavioural Pharmacology. 26, 4, p. 403-406

Research output: Contribution to journalArticleAcademicpeer-review

Deep brain stimulation of the forniceal area enhances memory functions in experimental dementia: The role of stimulation parameters

Hescham, S., Lim, L. W., Jahanshahi, A., Steinbusch, H. W. M., Prickaerts, J., Blokland, A. & Temel, Y., 1 Jan 2013, In : Brain stimulation. 6, 1, p. 72-77 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Defeat stress in rodents: From behavior to molecules

Hammels, C., Pishva, E., De Vry, J., van den Hove, D. L. A., Prickaerts, J., van Winkel, R., Selten, J-P., Lesch, K-P., Daskalakis, N. P., Steinbusch, H. W. M., van Os, J., Kenis, G. & Rutten, B. P. F., Dec 2015, In : Neuroscience and Biobehavioral Reviews. 59, p. 111-40 30 p.

Research output: Contribution to journalArticleAcademicpeer-review