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Research Output 1999 2019

Diurnal Variation of Markers for Cholesterol Synthesis, Cholesterol Absorption, and Bile Acid Synthesis: A Systematic Review and the Bispebjerg Study of Diurnal Variations

Schroor, M. M., Sennels, H. P., Fahrenkrug, J., Jorgensen, H. L., Plat, J. & Mensink, R. P., Jul 2019, In : Nutrients. 11, 7, 21 p., 1439.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Modifying Serum Plant Sterol Concentrations: Effects on Markers for Whole Body Cholesterol Metabolism in Children Receiving Parenteral Nutrition and Intravenous Lipids

Plat, J., Baumgartner, S., Vreugdenhil, A. C. E., Konings, M. C. J. M., Calkins, K. L. & Mensink, R. P., Jan 2019, In : Nutrients. 11, 1, p. 1-9 9 p., 120.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Non-Cholesterol Sterol Concentrations as Biomarkers for Cholesterol Absorption and Synthesis in Different Metabolic Disorders: A Systematic Review

Mashnafi, S., Plat, J., Mensink, R. P. & Baumgartner, S., Jan 2019, In : Nutrients. 11, 1, p. 1-31 31 p., 124.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?"

Plat, J., Baumgartner, S., Vanmierlo, T., Luetjohann, D., Calkins, K. L., Burrin, D. G., Guthrie, G., Thijs, C., Te Velde, A. A., Vreugdenhil, A. C. E., Sverdlov, R., Garssen, J., Wouters, K., Trautwein, E. A., Wolfs, T. G., van Gorp, C., Mulder, M. T., Riksen, N. P., Groen, A. K. & Mensink, R. P., Apr 2019, In : Progress in Lipid Research. 74, p. 87-102 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Plasma oxyphytosterol concentrations are not associated with CVD status in Framingham Offspring Study participants[S]

Baumgartner, S., Ras, R. T., Trautwein, E. A., Konings, M. C. J. M., Mensink, R. P. & Plat, J., Nov 2019, In : Journal of Lipid Research. 60, 11, p. 1905-1911 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Protection of the Ovine Fetal Gut against Ureaplasma-Induced Chorioamnionitis: A Potential Role for Plant Sterols

van Gorp, C., de Lange, I. H., Spiller, O. B., Dewez, F., Pastor, B. C., Heeren, R. M. A., Kessels, L., Kloosterboer, N., van Gemert, W. G., Beeton, M. L., Stock, S. J., Jobe, A. H., Payne, M. S., Kemp, M. W., Zimmermann, L. J., Kramer, B. W., Plat, J. & Wolfs, T. G. A. M., May 2019, In : Nutrients. 11, 5, p. 1-21 21 p., 968.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The effects of short-chain fatty acids on the transcription and secretion of apolipoprotein A-I in human hepatocytes in vitro

Tayyeb, J. Z., Popeijus, H. E., Mensink, R. P., Konings, M. C. J. M., Mulders, K. H. R. & Plat, J., Oct 2019, In : Journal of Cellular Biochemistry. 120, 10, p. 17219-17227 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Theobromine consumption does not improve fasting and postprandial vascular function in overweight and obese subjects

Smolders, L., Mensink, R. P., van den Driessche, J. J., Joris, P. J. & Plat, J., Apr 2019, In : European Journal of Nutrition. 58, 3, p. 981-987 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comment on Tauriainen et al. Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD

Plat, J., Baumgartner, S., Houben, T., Vreugdenhil, A. C. E., Mensink, R. P., Luetjohann, D. & Shiri-Sverdlov, R., 31 Oct 2018, In : Bioscience Reports. 38, 2 p., 20180505.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Determinants of cholesterol efflux capacity in humans

Talbot, C., Plat, J., Ritsch, A. & Mensink, R., 2018, In : Progress in Lipid Research. 69, p. 21-32

Research output: Contribution to journalReview articleAcademicpeer-review

Effects of gut microbiota manipulation on ex vivo lipolysis in human abdominal subcutaneous adipocytes

Jocken, J. W. E., Reijnders, D., Canfora, E. E., Boekschoten, M. V., Plat, J., Goossens, G. H. & Blaak, E. E., 1 Jan 2018, In : Adipocyte. 7, 2, p. 106-112 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effects of superfoods on risk factors of metabolic syndrome: a systematic review of human intervention trials

van den Driessche, J. J., Plat, J. & Mensink, R. P., 1 Apr 2018, In : Food & Function. 9, 4, p. 1944-1966 23 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Exogenously Added Oxyphytosterols Do Not Affect Macrophage-Mediated Inflammatory Responses

Oligschlaeger, Y., Houben, T., Jeurissen, M. L. J., Bitorina, A. V., Konings, M., Baumgartner, S., Plat, J. & Shiri-Sverdlov, R., Apr 2018, In : Lipids. 53, 4, p. 457-462 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Progress and perspectives in plant sterol and plant stanol research

Jones, P. J. H., Shamloo, M., MacKay, D. S., Rideout, T. C., Myrie, S. B., Plat, J., Roullet, J-B., Baer, D. J., Calkins, K. L., Davis, H. R., Duell, P. B., Ginsberg, H., Gylling, H., Jenkins, D., Luetjohann, D., Moghadasian, M., Moreau, R. A., Mymin, D., Ostlund, R. E., Ras, R. T. & 5 others, Reparaz, J. O., Trautwein, E. A., Turley, S., Vanmierlo, T. & Weingaetner, O., Oct 2018, In : Nutrition Reviews. 76, 10, p. 725-746 22 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The acute effects on duodenal gene expression in healthy men following consumption of a low-fat meal enriched with theobromine or fat

Smolders, L., Mensink, R. P., Boekschoten, M. V., de Ridder, R. J. J. & Plat, J., 26 Jan 2018, In : Scientific Reports. 8, 1, 11 p., 1700.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Theobromine Does Not Affect Fasting and Postprandial HDL Cholesterol Efflux Capacity, While It Decreases Fasting miR-92a Levels in Humans

Talbot, C. P. J., Mensink, R. P., Smolders, L., Bakeroot, V. & Plat, J., Jul 2018, In : Molecular Nutrition & Food Research. 62, 13, 8 p., 1800027.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Theobromine does not affect postprandial lipid metabolism and duodenal gene expression, but has unfavorable effects on postprandial glucose and insulin responses in humans

Smolders, L., Mensink, R. P., Boekschoten, M. V., de Ridder, R. J. J. & Plat, J., Apr 2018, In : Clinical Nutrition. 37, 2, p. 719-727 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

An acute intake of theobromine does not change postprandial lipid metabolism, whereas a high-fat meal lowers chylomicron particle number

Smolders, L., Mensink, R. P. & Plat, J., Apr 2017, In : Nutrition Research. 40, p. 85-94 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Association of TSH With Cardiovascular Disease Risk in Overweight and Obese Children During Lifestyle Intervention

Rijks, J. M., Plat, J., Dorenbos, E., Penders, B., Gerver, W-J. M. & Vreugdenhil, A. C. E., Jun 2017, In : Journal of Clinical Endocrinology & Metabolism. 102, 6, p. 2051-2058 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

C/EBP-beta Is Differentially Affected by PPAR alpha Agonists Fenofibric Acid and GW7647, But Does Not Change Apolipoprotein A-I Production During ER-Stress and Inflammation

van der Krieken, S. E., Popeijus, H. E., Konings, M., Dullens, S. P. J., Mensink, R. P. & Plat, J., Apr 2017, In : Journal of Cellular Biochemistry. 118, 4, p. 754-763 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Capable and credible? Challenging nutrition science

Penders, B., Wolters, A., Feskens, E. F., Brouns, F., Huber, M., Maeckelberghe, E. L. M., Navis, G., Ockhuizen, T., Plat, J., Sikkema, J., Stasse-Wolthuis, M., van 't Veer, P., Verweij, M. & de Vries, J., Sep 2017, In : European Journal of Nutrition. 56, 6, p. 2009-2012 4 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Cathepsin D regulates lipid metabolism in murine steatohepatitis

Houben, T., Oligschlaeger, Y., Hendrikx, T., Bitorina, A. V., Walenbergh, S. M. A., van Gorp, P. J., Gijbels, M. J. J., Friedrichs, S., Plat, J., Schaap, F. G., Luetjohann, D., Hofker, M. H. & Shiri-Sverdlov, R., 14 Jun 2017, In : Scientific Reports. 7, 10 p., 3494.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Dietary Strategies and Novel Pharmaceutical Approaches Targeting Serum ApoA-I Metabolism: A Systematic Overview

Smolders, L., Plat, J. & Mensink, R. P., 2017, In : Journal of Nutrition and Metabolism. 28 p., 5415921.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Effect of Theobromine Consumption on Serum Lipoprotein Profiles in Apparently Healthy Humans with Low HDL-Cholesterol Concentrations

Jacobs, D. M., Smolders, L., Yuguang, L., de Roo, N., Trautwein, E. A., van Duynhoven, J., Mensink, R., Plat, J. & Mihaleva, V. V., Aug 2017, In : Frontiers in Molecular Biosciences. 4, 11 p., 59.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Effects of NWT-03, an egg-protein hydrolysate, on blood pressure in normotensive, high-normotensive and mild-hypertensive men and women: a dose-finding study

Plat, J., Severins, N., Morrison, S. & Mensink, R. P., Apr 2017, In : British Journal of Nutrition. 117, 7, p. 942-950 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of plant stanol ester consumption on fasting plasma oxy(phyto)sterol concentrations as related to fecal microbiota characteristics

Baumgartner, S., Mensink, R. P., de Smet, E., Konings, M., Fuentes, S., de Vos, W. M. & Plat, J., May 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 169, p. 46-53 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-kappa B/STAT1-IRF1 Signaling

van der Vorst, E. P. C., Theodorou, K., Wu, Y., Hoeksema, M. A., Goossens, P., Bursill, C. A., Aliyev, T., Huitema, L. F. A., Tas, S. W., Wolfs, I. M. J., Kuijpers, M. J. E., Gijbels, M. J., Schalkwijk, C. G., Koonen, D. P. Y., Abdollahi-Roodsaz, S., McDaniels, K., Wang, C-C., Leitges, M., Lawrence, T., Plat, J. & 6 others, Van Eck, M., Rye, K-A., Touqui, L., de Winther, M. P. J., Biessen, E. A. L. & Donners, M. M. P. C., 10 Jan 2017, In : Cell Metabolism. 25, 1, p. 197-207 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Independent tissue contributors to obesity-associated insulin resistance

Kusters, Y. H. A. M., Schalkwijk, C. G., Houben, A. J. H. M., Kooi, M. E., Lindeboom, L., 't Roodt, J. O., Joris, P. J., Plat, J., Mensink, R. P., Barrett, E. J. & Stehouwer, C. D. A., 6 Jul 2017, In : JCI INSIGHT. 2, 13, 11 p., e89695.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Link Between ER-Stress, PPAR-Alpha Activation, and BET Inhibition in Relation to Apolipoprotein A-I Transcription in HepG2 Cells

van der Krieken, S. E., Popeijus, H. E., Mensink, R. P. & Plat, J., Aug 2017, In : Journal of Cellular Biochemistry. 118, 8, p. 2161-2167 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipoprotein Changes Following Consumption of Lutein-enriched Eggs are Associated with Enhanced Lutein Bioavailability

Kijlstra, A., van der Made, S. M., Plat, J. & Berendschot, T. T. J. M., 17 May 2017, In : Journal of Food and Nutrition Research. 5, 6, p. 362-369 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

One-year daily consumption of buttermilk drink containing lutein-enriched egg-yolks does not affect endothelial function in fasting and postprandial state

van der Made, S. M., Berendschot, T. T. J. M., Kijlstra, A. & Plat, J., 2 May 2017, In : Scientific Reports. 7, 1, 7 p., 1353.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Oxidation of sitosterol and transport of its 7-oxygenated products from different tissues in humans and ApoE knockout mice

Schoett, H-F., Baumgartner, S., Husche, C., Luister, A., Friedrichs, S., Miller, C. M., McCarthy, F. O., Plat, J., Laufs, U., Weingaertner, O. & Luetjohann, D., May 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 169, p. 145-151 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Plasma fat-soluble vitamin and carotenoid concentrations after plant sterol and plant stanol consumption: a meta-analysis of randomized controlled trials

Baumgartner, S., Ras, R. T., Trautwein, E. A., Mensink, R. P. & Plat, J., Apr 2017, In : European Journal of Nutrition. 56, 3, p. 909-923 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Response to Letter to the Editor: "Association of TSH With Cardiovascular Disease Risk in Overweight and Obese Children During Lifestyle Intervention"

Plat, J. & Vreugdenhil, A. C. E., 1 Dec 2017, In : Journal of Clinical Endocrinology & Metabolism. 102, 12, p. 4660-4661 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

The effects of amoxicillin and vancomycin on parameters reflecting cholesterol metabolism

Baumgartner, S., Reijnders, D., Konings, M. C. J. M., Groen, A. K., Luetjohann, D., Goossens, G. H., Blaak, E. E. & Plat, J., Oct 2017, In : Chemistry and Physics of Lipids. 207, p. 239-245 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effects of vitamin E or lipoic acid supplementation on oxyphytosterols in subjects with elevated oxidative stress: a randomized trial

Baumgartner, S., Mensink, R. P., Haenen, G. R., Bast, A., Binder, C. J., Bekers, O., Husche, C., Luetjohann, D. & Plat, J., 10 Nov 2017, In : Scientific Reports. 7, 9 p., 15288.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2016

Dietary plant stanol ester consumption improves immune function in asthma patients: results of a randomized, double-blind clinical trial

Brüll, F., de Smet, E., Mensink, R. P., Vreugdenhil, A., Kerksiek, A., Lutjohann, D., Wesseling, G. & Plat, J., Feb 2016, In : American Journal of Clinical Nutrition. 103, 2, p. 444-453 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of a Plant Sterol or Stanol Enriched Mixed Meal on Postprandial Lipid Metabolism in Healthy Subjects

Baumgartner, S., Mensink, R. P. & Plat, J., 9 Sep 2016, In : PLOS ONE. 11, 9

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

EFFECTS OF VITAMIN E OR LIPOIC ACID SUPPLEMENTATION ON FASTING OXYPHYTOSTEROL CONCENTRATIONS IN SUBJECTS WITH IMPAIRED GLUCOSE TOLERANCE OR TYPE II DIABETES

Baumgartner, S., Mensink, R. P., Haenen, G., Bast, A., Binder, C., Bekers, O., Husche, C., Luetjohann, D. & Plat, J., Sep 2016, In : Atherosclerosis. 252, p. E89-E89 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Glycaemic Profiles of Children With Overweight and Obesity in Free-living Conditions in Association With Cardiometabolic Risk

Rijks, J., Karnebeek, K., van Dijk, J-W., Dorenbos, E., Gerver, W., Stouthart, P., Plat, J. & Vreugdenhil, A., 18 Aug 2016, In : Scientific Reports. 6, 31892.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access