20152019

Research output per year

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Research Output

2019

A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients

Sternkopf, M., Thoroee-Boveleth, S., Beck, T., Oleschko, K., Erlenkoetter, A., Tschulena, U., Steppan, S., Speer, T., Goettsch, C., Jankowski, V., Jankowski, J., Noels, H. & European Uremic Toxin Work Grp, Jul 2019, In : Toxins. 11, 7, 17 p., 389.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances

Vollmer, T., Ljungberg, B., Jankowski, V., Jankowski, J., Glorieux, G. & Stegmayr, B. G., 10 Oct 2019, In : Scientific Reports. 9, 11 p., 14525.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach

Gajjala, P. R., Bruck, H., Noels, H., Heinze, G., Ceccarelli, F., Kribben, A., Saez-Rodriguez, J., Marx, N., Zidek, W., Jankowski, J. & Jankowski, V., Oct 2019, In : Journal of Molecular Medicine. 97, 10, p. 1451-1463 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease

van der Made, T. K., Fedecostante, M., Scotcher, D., Rostami-Hodjegan, A., Torano, J. S., Middel, I., Koster, A. S., Gerritsen, K. G., Jankowski, V., Jankowski, J., Hoenderop, J. G. J., Masereeuw, R. & Galetin, A., Nov 2019, In : Molecular Pharmaceutics. 16, 11, p. 4551-4562 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling

Magalhaes, P., Pontillo, C., Pejchinovski, M., Siwy, J., Krochmal, M., Makridakis, M., Carrick, E., Klein, J., Mullen, W., Jankowski, J., Vlahou, A., Mischak, H., Schanstra, J. P., Zurbig, P. & Pape, L., 1 Sep 2018, In : Proteomics Clinical Applications. 12, 5, 9 p., 1700163.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of extracts prepared from modified porous poly(ether imide) microparticulate absorbers on cytotoxicity, macrophage differentiation and proinflammatory behavior of human monocytic (THP-1) cells

Kumar, R. K., Heuchel, M., Kratz, K., Lendlein, A., Jankowski, J. & Tetali, S. D., 1 Jan 2018, In : Clinical Hemorheology and Microcirculation. 69, 1-2, p. 175-185 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease

Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. & Jankowski, V., 6 Nov 2018, In : Neurology. 91, 19, p. E1799-E1808 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis

Schmitz, C., Noels, H., El Bounkari, O., Straussfeld, E., Megens, R. T. A., Sternkopf, M., Alampour-Rajabi, S., Krammer, C., Tilstam, P. V., Gerdes, N., Burger, C., Kapurniotu, A., Bucala, R., Jankowski, J., Weber, C. & Bernhagen, J., 1 Aug 2018, In : Faseb Journal. 32, 8, p. 4428-4443 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery

Noels, H., Theelen, W., Sternkopf, M., Jankowski, V., Moellmann, J., Kraemer, S., Lehrke, M., Marx, N., Martin, L., Marx, G., Jankowski, J., Goetzenich, A. & Stoppe, C., 7 Aug 2018, In : Scientific Reports. 8, 12 p., 11820.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Targeting proinflammatory cytokines ameliorates calcifying phenotype conversion of vascular progenitors under uremic conditions in vitro

Hegner, B., Schaub, T., Janke, D., Zickler, D., Lange, C., Girndt, M., Jankowski, J., Schindler, R. & Dragun, D., 14 Aug 2018, In : Scientific Reports. 8, 11 p., 12087.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability

Sawant, M., Schwarz, N., Windoffer, R., Magin, T. M., Krieger, J., Mucke, N., Obara, B., Jankowski, V., Jankowski, J., Wally, V., Lettner, T. & Leube, R. E., 1 Mar 2018, In : Journal of Investigative Dermatology. 138, 3, p. 627-636 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

A urinary proteome-based classifier for the early detection of decline in glomerular filtration

Pontillo, C., Jacobs, L., Staessen, J. A., Schanstra, J. P., Rossing, P., Heerspink, H. J. L., Siwy, J., Mullen, W., Vlahou, A., Mischak, H., Vanholder, R., Zuerbig, P. & Jankowski, J., Sep 2017, In : Nephrology Dialysis Transplantation. 32, 9, p. 1510-1516 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Back-calculating baseline creatinine overestimates prevalence of acute kidney injury with poor sensitivity

Kork, F., Balzer, F., Krannich, A., Bernardi, M. H., Eltzschig, H. K., Jankowski, J. & Spies, C., Mar 2017, In : Acta Physiologica. 219, 3, p. 615-626 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Disposition and clinical implications of protein-bound uremic toxins

Jansen, J., Jankowski, J., Gajjala, P. R., Wetzels, J. F. M. & Masereeuw, R., 15 Jul 2017, In : Clinical Science. 131, 14, p. 1631-1647 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis

Krochmal, M., Cisek, K., Filip, S., Markoska, K., Orange, C., Zoidakis, J., Gakiopoulou, C., Spasovski, G., Mischak, H., Delles, C., Vlahou, A. & Jankowski, J., 22 Aug 2017, In : Scientific Reports. 7, 13 p., 9091.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo

Asare, Y., Ommer, M., Azombo, F. A., Alampour-Rajabi, S., Sternkopf, M., Sanati, M., Gijbels, M. J., Schmitz, C., Sinitski, D., Tilstam, P. V., Lue, H., Gessner, A., Lange, D., Schmid, J. A., Weber, C., Dichgans, M., Jankowski, J., Pardi, R., de Winther, M. P. J., Noels, H. & 1 others, Bernhagen, J., 14 Mar 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 13, p. E2766-E2775 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis

Siwy, J., Zuerbig, P., Argiles, A., Beige, J., Haubitz, M., Jankowski, J., Julian, B. A., Linde, P. G., Marx, D., Mischak, H., Mullen, W., Novak, J., Ortiz, A., Persson, F., Pontillo, C., Rossing, P., Rupprecht, H., Schanstra, J. P., Vlahou, A. & Vanholder, R., Dec 2017, In : Nephrology Dialysis Transplantation. 32, 12, p. 2079-2089 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker

Pontillo, C., Zhang, Z-Y., Schanstra, J. P., Jacobs, L., Zuerbig, P., Thijs, L., Ramirez-Torres, A., Heerspink, H. J. L., Lindhardt, M., Klein, R., Orchard, T., Porta, M., Bilous, R. W., Charturvedi, N., Rossing, P., Vlahou, A., Schepers, E., Glorieux, G., Mullen, W., Delles, C. & 5 others, Verhamme, P., Vanholder, R., Staessen, J. A., Mischak, H. & Jankowski, J., Nov 2017, In : Kidney International Reports. 2, 6, p. 1066-1075 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Proteome Analysis: New Approaches for Improved Treatment of Diabetic Nephropathy

Drube, J., Zuerbig, P., Beige, J., Mischak, H. & Jankowski, J., Jun 2017, In : Diabetologie Und Stoffwechsel. 12, 3, p. 213-221 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma

Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W. & Jankowski, J., Aug 2017, In : Hypertension. 70, 2, p. 412-419 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation

Rowinska, Z., Koeppel, T. A., Sanati, M., Schelzig, H., Jankowski, J., Weber, C., Zernecke, A. & Liehn, E. A., 24 Feb 2017, In : PLOS ONE. 12, 2, 9 p., 0170644.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Adsorption capacity of poly(ether imide) microparticles to uremic toxins

Tetali, S. D., Jankowski, V., Luetzow, K., Kratz, K., Lendlein, A. & Jankowski, J., 2016, In : Clinical Hemorheology and Microcirculation. 61, 4, p. 657-665

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

alpha-1-Antitrypsin detected by MALDI imaging in the study of glomerulonephritis: Its relevance in chronic kidney disease progression

Smith, A., L'Imperio, V., De Sio, G., Ferrario, F., Scalia, C., Dell'Antonio, G., Pieruzzi, F., Pontillo, C., Filip, S., Markoska, K., Granata, A., Spasovski, G., Jankowski, J., Capasso, G., Pagni, F. & Magni, F., Jun 2016, In : Proteomics. 16, 11-12, p. 1759-1766

Research output: Contribution to journalArticleAcademicpeer-review

Influence of nanoporous poly(ether imide) particle extracts on human aortic endothelial cells (HAECs)

Kumar, R. K., Basu, S., Lemke, H-D., Jankowski, J., Kratz, K., Lendlein, A. & Tetali, S. D., 2016, In : Clinical Hemorheology and Microcirculation. 64, 4, p. 931-940 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Oxidative Stress in Chronic Kidney Disease

Scholze, A., Jankowski, J., Pedraza-Chaverri, J. & Evenepoel, P., 2016, In : Oxidative Medicine and Cellular Longevity. 2016, 8375186.

Research output: Contribution to journalEditorialAcademicpeer-review

1 Citation (Scopus)

PeptiCKDdb-peptide- and protein-centric database for the investigation of genesis and progression of chronic kidney disease

Krochmal, M., Fernandes, M., Filip, S., Pontillo, C., Husi, H., Zoidakis, J., Mischak, H., Vlahou, A. & Jankowski, J., 1 Sep 2016, In : Database-The Journal of Biological Databases and Curation. 2016, baw128.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2015

Atheroprotective role of C5ar2 deficiency in apolipoprotein E-deficient mice

Selle, J., Asare, Y., Kohncke, J., Alampour-Rajabi, S., Shagdarsuren, G., Klos, A., Weber, C., Jankowski, J. & Shagdarsuren, E., Oct 2015, In : Thrombosis and Haemostasis. 114, 4, p. 848-858

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease

Gajjala, P. R., Fliser, D., Speer, T., Jankowski, V. & Jankowski, J., Nov 2015, In : Nephrology Dialysis Transplantation. 30, 11, p. 1814-1824

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Guanidinylations of albumin decreased binding capacity of hydrophobic metabolites

Rueth, M., Lemke, H. -D., Preisinger, C., Krieter, D., Theelen, W., Gajjala, P., Devine, E., Zidek, W., Jankowski, J. & Jankowski, V., Sep 2015, In : Acta Physiologica. 215, 1, p. 13-23

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Identification of the Vasoconstriction-Inhibiting Factor (VIF), a Potent Endogenous Cofactor of Angiotensin II Acting on the Angiotensin II Type 2 Receptor

Salem, S., Jankowski, V., Asare, Y., Liehn, E., Welker, P., Raya-Bermudez, A., Pineda-Martos, C., Rodriguez, M., Rafael Munoz-Castaneda, J., Bruck, H., Marx, N., Machado, F. B., Staudt, M., Heinze, G., Zidek, W. & Jankowski, J., 21 Apr 2015, In : Circulation. 131, 16, p. 1426-1434

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis

Glorieux, G., Mullen, W., Duranton, F., Filip, S., Gayrard, N., Husi, H., Schepers, E., Neirynck, N., Schanstra, J. P., Jankowski, J., Mischak, H., Argiles, A., Vanholder, R., Vlahou, A. & Klein, J., Nov 2015, In : Nephrology Dialysis Transplantation. 30, 11, p. 1842-1852

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes

Pena, M. J., Jankowski, J., Heinze, G., Kohl, M., Heinzel, A., Bakker, S. J. L., Gansevoort, R. T., Rossing, P., de Zeeuw, D., Heerspink, H. J. L. & Jankowski, V., Oct 2015, In : Journal of Hypertension. 33, 10, p. 2123-2132

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)