20152019

Research output per year

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Research Output

  • 6 Article
  • 1 Review article
  • 1 Doctoral Thesis

Development of novel tools for the in vitro investigation of drug-induced liver injury

Jiang, J., Wolters, J. EJ., van Breda, S. G., Kleinjans, J. C. & de Kok, T. M., 3 Oct 2015, In : Expert Opinion on Drug Metabolism & Toxicology. 11, 10, p. 1523-1537 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Human 3D multicellular microtissues: An upgraded model for the in vitro mechanistic investigation of inflammation-associated drug toxicity

Jiang, J., Messner, S., Kelm, J. M., van Herwijnen, M., Jennen, D. G. J., Kleinjans, J. C. & de Kok, T. M., 15 Sep 2019, In : Toxicology Letters. 312, p. 34-44 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain

Jiang, J., Briede, J. J., Jennen, D. G. J., Van Summeren, A., Saritas-Brauers, K., Schaart, G., Kleinjans, J. C. S. & de Kok, T. M. C. M., 16 Apr 2015, In : Toxicology Letters. 234, 2, p. 139-150

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury

Jiang, J., Mathijs, K., Timmermans, L., Claessen, S. M., Hecka, A., Weusten, J., Peters, R., van Delft, J. H., Kleinjans, J. C. S., Jennen, D. G. J. & de Kok, T. M., 1 Oct 2017, In : Toxicology and Applied Pharmacology. 332, p. 100-108 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Response to cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity

Jiang, J., Briede, J. J., Jennen, D. G. J., Kleinjans, J. C. S. & de Kok, T. M. C. M., 15 Jun 2015, In : Toxicology Letters. 235, 3, p. 218-219

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro

Jiang, J., Pieterman, C. D., Ertaylan, G., Peeters, R. L. M. & de Kok, T. M. C. M., 5 Oct 2019, In : Archives of Toxicology. 93, 11, p. 3067-3098 32 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The idiosyncratic drug-induced gene expression changes in HepG2 cells

Jiang, J., Mathijs, K., Timmermans, L., Claessen, S. M., Hecka, A., Weusten, J., Peters, R., van Delft, J. H., Kleinjans, J. C. S., Jennen, D. G. J. & de Kok, T. M., Oct 2017, In : Data in brief. 14, p. 462-468 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access