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Research Output 2017 2019

  • 11 Article
  • 1 Erratum / corrigendum
  • 1 Doctoral Thesis
2019

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

van Maurik, I. S., Vos, S. J., Bos, I., Bouwman, F. H., Teunissen, C. E., Scheltens, P., Barkhof, F., Frolich, L., Kornhuber, J., Wiftfang, J., Maier, W., Peters, O., ROther, E., Nobili, F., Frisoni, G. B., Spiru, L., Freund-Levi, Y., Wallin, A. K., Hampel, H., Soininen, H. & 19 others, Tsolaki, M., Verhey, F., Kloszewska, I., Mecocci, P., Vellas, B., Lovestone, S., Gailuzzi, S., Herukka, S-K., Santana, I., Baldeiras, I., de Mendonca, A., Silva, D., Chetelat, G., Egret, S., Palmqvist, S., Hansson, O., Visser, P. J., Berkhof, J. & van der Flier, W. M., Nov 2019, In : Lancet Neurology. 18, 11, p. 1034-1044 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

Bos, I., Vos, S., Verhey, F., Scheltens, P., Teunissen, C., Engelborghs, S., Sleegers, K., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Tsolaki, M., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Lleo, A., Johannsen, P., Freund-Levi, Y., Froelich, L. & 12 others, Vandenberghe, R., Westwood, S., Dobricic, V., Barkhof, F., Legido-Quigley, C., Bertram, L., Lovestone, S., Streffer, J., Andreasson, U., Blennow, K., Zetterberg, H. & Visser, P. J., May 2019, In : Alzheimer's & Dementia. 15, 5, p. 644-654 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Shi, L., Westwood, S., Baird, A. L., Winchester, L., Dobricic, V., Kilpert, F., Hong, S., Franke, A., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Buckley, N. J., ten Kate, M., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S. & 33 others, De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleo, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Froelich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Zetterberg, H., Baker, S., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Lovestone, S. & Nevado-Holgado, A. J., Nov 2019, In : Alzheimer's & Dementia. 15, 11, p. 1478-1488 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

Vermunt, L., Sikkes, S. A. M., van den Hout, A., Handels, R., Bos, I., van der Flier, W. M., Kern, S., Ousset, P-J., Maruff, P., Skoog, I., Verhey, F. R. J., Freund-Levi, Y., Tsolaki, M., Wallin, A. K., Rikkert, M. O., Soininen, H., Spiru, L., Zetterberg, H., Blennow, K., Scheltens, P. & 30 others, Muniz-Terrera, G., Visser, P. J., Vellas, B., Reynish, E., Ousset, P. J., Andrieu, S., Burns, A., Pasquier, F., Frisoni, G., Salmon, E., Michel, J. P., Zekry, D. S., Boada, M., Dartigues, J. F., Olde-Rikkert, M. G. M., Rigaud, A. S., Winblad, B., Malick, A., Sinclair, A., Froelich, L., Scheltens, P., Ribera, C., Touchon, J., Robert, P., Salva, A., Waldemar, G., Bullock, R., Tsolaki, M., Rodriguez, G. & Spiru, L., Jul 2019, In : Alzheimer's & Dementia. 15, 7, p. 888-898 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inflammatory biomarkers in Alzheimer's disease plasma

Morgan, A. R., Touchard, S., Leckey, C., O'Hagan, C., Nevado-Holgado, A. J., Barkhof, F., Bertram, L., Blin, O., Bos, I., Dobricic, V., Engelborghs, S., Frisoni, G., Froelich, L., Gabel, S., Johannsen, P., Kettunen, P., Koszewska, I., Legido-Quigley, C., Lleo, A., Martinez-Lage, P. & 30 others, Mecocci, P., Meersmans, K., Luis Molinuevo, J., Peyratout, G., Popp, J., Richardson, J., Sala, I., Scheltens, P., Streffer, J., Soininen, H., Tainta-Cuezva, M., Teunissen, C., Tsolaki, M., Vandenberghe, R., Visser, P. J., Vos, S., Wahlund, L-O., Wallin, A., Westwood, S., Zetterberg, H., Lovestone, S., Morgan, B. P., Bullmore, E. T., Bhatti, J., Chamberlain, S. J., Correia, M. M., Crofts, A. L., Dickinson, A., Foster, A. C. & Kitzbichler, M. G., Jun 2019, In : Alzheimer's & Dementia. 15, 6, p. 776-787 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vascular risk factors are associated with longitudinal changes in cerebrospinal fluid tau markers and cognition in preclinical Alzheimer's disease

Bos, I., Vos, S. J. B., Schindler, S. E., Hassenstab, J., Xiong, C., Grant, E., Verhey, F., Morris, J. C., Visser, P. J. & Fagan, A. M., Sep 2019, In : Alzheimer's & Dementia. 15, 9, p. 1149-1159 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Amyloid-beta, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data

Bos, I., Vos, S. J. B., Jansen, W. J., Vandenberghe, R., Gabel, S., Estanga, A., Ecay-Torres, M., Tomassen, J., den Braber, A., Lleo, A., Sala, I., Wallin, A., Kettunen, P., Molinuevo, J. L., Rami, L., Chetelat, G., de la Sayette, V., Tsolaki, M., Freund-Levi, Y., Johannsen, P. & 4 others, Novak, G. P., Ramakers, I., Verhey, F. R. & Visser, P. J., 25 Jun 2018, In : Frontiers in Aging Neuroscience. 10, 11 p., 193.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Open Access
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Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline (vol 9, 101, 2017)

Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Wallin, A. K., van Buchem, M. A., Oleksik, A., Verbeek, M. M., Rikkert, M. O., van der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 20 Jun 2018, In : Alzheimer's Research & Therapy. 10, 3 p., 56.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study

ten Kate, M., Redolfi, A., Peira, E., Bos, I., Vos, S. J., Vandenberghe, R., Gabel, S., Schaeverbeke, J., Scheltens, P., Blin, O., Richardson, J. C., Bordet, R., Wallin, A., Eckerstrom, C., Molinuevo, J. L., Engelborghs, S., Van Broeckhoven, C., Martinez-Lage, P., Popp, J., Tsolaki, M. & 17 others, Verhey, F. R. J., Baird, A. L., Legido-Quigley, C., Bertram, L., Dobricic, V., Zetterberg, H., Lovestone, S., Streffer, J., Bianchetti, S., Novak, G. P., Revillard, J., Gordon, M. F., Xie, Z., Wottschel, V., Frisoni, G., Visser, P. J. & Barkhof, F., 27 Sep 2018, In : Alzheimer's Research & Therapy. 10, 12 p., 100.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics

Bos, I., Vos, S., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G., Molinuevo, J., Wallin, A., Lleo, A., Popp, J., Martinez-Lage, P., Baird, A., Dobson, R., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Bertram, L., ten Kate, M., Barkhof, F., Zetterberg, H. & 3 others, Lovestone, S., Streffer, J. & Visser, P. J., 6 Jul 2018, In : Alzheimer's Research & Therapy. 10, 9 p., 64.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Wallin, A. K., van Buchem, M. A., Oleksik, A., Verbeek, M. M., Rikkert, M. O., van der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 29 Dec 2017, In : Alzheimer's Research & Therapy. 9, 10 p., 101.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

Bos, I., Vos, S. J., Froelich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Ruether, E., Engelborghs, S., Niemantsverdriet, E., De Roeck, E. E., Tsolaki, M., Freund-Levim, Y., Johannsen, P., Vandenberghe, R., Lleo, A., Alcolea, D., Frisoni, G. B., Galluzzi, S., Nobili, F. & 25 others, Morbelli, S., Drzezga, A., Didic, M., van Berckel, B. N., Salmon, E., Bastin, C., Dauby, S., Santana, I., Baldeiras, I., de Mendonca, A., Silva, D., Wallin, A., Nordlund, A., Coloma, P. M., Wientzek, A., Alexander, M., Novak, G. P., Gordon, M. F., Wallin, A. K., Hampel, H., Soininen, H., Herukka, S-K., Scheltens, P., Verhey, F. R. & Visser, P. J., Aug 2017, In : Neurobiology of Aging. 56, p. 33-40 8 p.

Research output: Contribution to journalArticleAcademicpeer-review