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Research Output 2012 2019

2019

Comprehensive biomarker analyses identifies HER2, EGFR, MET RNA expression and thymidylate synthase 5 ' UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer

Yoshikawa, T., Aoyama, T., Sakamaki, K., Oshima, T., Lin, J., Zhang, S., Sapari, N. S., Soong, R., Tan, I., Chan, X. B., Bottomley, D., Hewitt, L. C., Arai, T., Teh, B. T., Epstein, D., Ogata, T., Kameda, Y., Miyagi, Y., Tsuburaya, A., Morita, S. & 2 others, Grabsch, H. & Tan, P., 2019, In : Journal of Cancer. 10, 21, p. 5130-5138 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma

Jan 2019, In : Gastric Cancer. 22, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Correction to: Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma

Mar 2019, In : Gastric Cancer. 22, 2, p. 421-421 1 p.

Research output: Contribution to journalErratum / corrigendumAcademic

Correction to: KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Hewitt, L. C., Saito, Y., Wang, T., Matsuda, Y., Oosting, J., Silva, A. N. S., Slaney, H. L., Melotte, V., Hutchins, G., Tan, P., Yoshikawa, T., Arai, T. & Grabsch, H. I., Nov 2019, In : Gastric Cancer. 22, 6, p. 1204-1205 2 p.

Research output: Contribution to journalErratum / corrigendumAcademic

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Kather, J. N., Pearson, A. T., Halama, N., Jaeger, D., Krause, J., Loosen, S. H., Marx, A., Boor, P., Tacke, F., Neumann, U. P., Grabsch, H. I., Yoshikawa, T., Brenner, H., Chang-Claude, J., Hoffmeister, M., Trautwein, C. & Luedde, T., Jul 2019, In : Nature Medicine. 25, 7, p. 1054-+ 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial

Sundar, R., Ng, A., Zouridis, H., Padmanabhan, N., Sheng, T., Zhang, S., Lee, M. H., Ooi, W. F., Qamra, A., Inam, I., Hewitt, L. C., So, J. B-Y., Koh, V., Nankivell, M. G., Langley, R. E., Allum, W. H., Cunningham, D., Rozen, S. G., Yong, W. P., Grabsch, H. I. & 1 others, Tan, P., Dec 2019, In : European Journal of Cancer. 123, p. 48-57 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta-analysis of transcriptional subtypes

de Santiago, I., Yau, C., Heij, L., Middleton, M. R., Markowetz, F., Grabsch, H., Dustin, M. L. & Sivakumar, S., 15 Aug 2019, In : International Journal of Cancer. 145, 4, p. 1125-1137 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Hewitt, L. C., Saito, Y., Wang, T., Matsuda, Y., Oosting, J., Silva, A. N. S., Slaney, H. L., Melotte, V., Hutchins, G., Tan, P., Yoshikawa, T., Arai, T. & Grabsch, H. I., Nov 2019, In : Gastric Cancer. 22, 6, p. 1193-1203 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Quality assurance of surgery in the randomized ST03 trial of perioperative chemotherapy in carcinoma of the stomach and gastro-oesophageal junction

Allum, W. H., Smyth, E. C., Blazeby, J. M., Grabsch, H. I., Griffin, S. M., Rowley, S., Cafferty, F. H., Langley, R. E. & Cunningham, D., Aug 2019, In : British Journal of Surgery. 106, 9, p. 1204-1215 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Response assessment after (chemo)radiotherapy for rectal cancer: Why are we missing complete responses with MRI and endoscopy?

van der Sande, M. E., Beets, G. L., Hupkens, B. J. P., Breukink, S. O., Melenhorst, J., Bakers, F. C. H., Lambregts, D. M. J., Grabsch, H. I., Beets-Tan, R. G. H. & Maas, M., Jun 2019, In : European Journal of Surgical Oncology. 45, 6, p. 1011-1017 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Safety and Efficacy of the Addition of Lapatinib to Perioperative Chemotherapy for Resectable HER2-Positive Gastroesophageal Adenocarcinoma: A Randomized Phase 2 Clinical Trial

Smyth, E. C., Rowley, S., Cafferty, F. H., Allum, W., Grabsch, H. I., Stenning, S., Wotherspoon, A., Alderson, D., Crosby, T., Mansoor, W., Waters, J. S., Neville-Webbe, H., Darby, S., Dent, J., Seymour, M., Thompson, J., Sothi, S., Blazeby, J., Langley, R. E. & Cunningham, D., Aug 2019, In : JAMA Oncology. 5, 8, p. 1181-1187 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The 4th St. Gallen EORTC Gastrointestinal Cancer Conference: Controversial issues in the multimodal primary treatment of gastric, junctional and oesophageal adenocarcinoma

Lutz, M. P., Zalcberg, J. R., Ducreux, M., Adenis, A., Allum, W., Aust, D., Carneiro, F., Grabsch, H., Laurent-Puig, P., Lordick, F., Moehler, M., Monig, S., Obermannova, R., Piessen, G., Riddell, A., Roecken, C., Roviello, F., Schneider, P. M., Seewald, S., Smyth, E. & 4 others, van Cutsem, E., Verheij, M., Wagner, A. D. & Otto, F., May 2019, In : European Journal of Cancer. 112, p. 1-8 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Trends in treatment and overall survival among patients with proximal esophageal cancer

de Vos-Geelen, J., Geurts, S. M. E., van Putten, M., Valkenburg-van Iersel, L. B. J., Grabsch, H. I., Mohammad, N. H., Hoebers, F. J. P., Hoge, C. V., Jeene, P. M., de Jong, E. J. M., van Laarhoven, H. W. M., Rozema, T., Slingerland, M., Tjan-Heijnen, V. C. G., Nieuwenhuijzen, G. A. P. & Lemmens, V. E. P. P., 21 Dec 2019, In : World Journal of Gastroenterology. 25, 47, p. 6835-6846 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Acetone clearance of mesocolic or mesorectal fat increases lymph node yield and may improve detection of high-risk Stage II colorectal cancer patients

Leung, C. A. W., Fazzi, G. E., Melenhorst, J., Rennspiess, D. & Grabsch, H. I., Nov 2018, In : Colorectal Disease. 20, 11, p. 1014-1019 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

An international survey-based study on colorectal cancer pathology reporting: guidelines versus local practice

Urbanowicz, M., Grabsch, H. I., Fiteni, F., Liu, Y., Caballero, C. & Flejou, J-F., Dec 2018, In : Virchows Archiv. 473, 6, p. 697-708 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

CRITICS-II: a multicentre randomised phase II trial of neo-adjuvant chemotherapy followed by surgery versus neo-adjuvant chemotherapy and subsequent chemoradiotherapy followed by surgery versus neo-adjuvant chemoradiotherapy followed by surgery in resectable gastric cancer

Slagter, A. E., Jansen, E. P. M., van Laarhoven, H. W. M., van Sandick, J. W., van Grieken, N. C. T., Sikorska, K., Cats, A., Muller-Timmermans, P., Hulshof, M. C. C. M., Boot, H., Los, M., Beerepoot, L. V., Peters, F. P. J., Hospers, G. A. P., van Etten, B., Hartgrink, H. H., Henegouwen, M. I. V. B., Nieuwenhuijzen, G. A. P., van Hillegersberg, R., van der Peet, D. L. & 2 others, Grabsch, H. I. & Verheij, M., 10 Sep 2018, In : BMC Cancer. 18, 1, 12 p., 877.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Epstein-Barr virus and mismatch repair deficiency status differ between oesophageal and gastric cancer: A large multi-centre study

Hewitt, L. C., Inam, I. Z., Saito, Y., Yoshikawa, T., Quaas, A., Hoelscher, A., Bollschweiler, E., Fazzi, G. E., Melotte, V., Langley, R. E., Nankivell, M., Cunningham, D., Allum, W., Hutchins, G. G. & Grabsch, H. I., May 2018, In : European Journal of Cancer. 94, p. 104-114 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Frequent Coamplification of Receptor Tyrosine Kinase and Downstream Signaling Genes in Japanese Primary Gastric Cancer and Conversion in Matched Lymph Node Metastasis

Silva, A. N. S., Coffa, J., Menon, V., Hewitt, L. C., Das, K., Miyagi, Y., Bottomley, D., Slaney, H., Aoyama, T., Mueller, W., Arai, T., Tan, I. B., Deng, N., Chan, X. B., Tan, P., Tsuburaya, A., Sakamaki, K., Hayden, J. D., Yoshikawa, T., Zondervan, I. & 2 others, Savola, S. & Grabsch, H. I., 1 Jan 2018, In : Annals of Surgery. 267, 1, p. 114-121 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of a high-risk subtype of intestinal-type Japanese gastric cancer by quantitative measurement of the luminal tumor proportion

Aoyama, T., Hutchins, G., Arai, T., Sakamaki, K., Miyagi, Y., Tsuburaya, A., Ogata, T., Oshima, T., Earle, S., Yoshikawa, T. & Grabsch, H. L., Oct 2018, In : Cancer Medicine. 7, 10, p. 4914-4923 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prognostic DNA methylation markers for sporadic colorectal cancer: a systematic review

Draht, M. X. G., Goudkade, D., Koch, A., Grabsch, H. I., Weijenberg, M. P., van Engeland, M., Melotte, V. & Smits, K. M., 14 Mar 2018, In : Clinical epigenetics. 10, 16 p., 35.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Prognostic value of pathological lymph node status and primary tumour regression grading following neoadjuvant chemotherapy - results from the MRC OE02 oesophageal cancer trial

Davarzani, N., Hutchins, G. G. A., West, N. P., Hewitt, L. C., Nankivell, M., Cunningham, D., Allum, W. H., Smyth, E., Valeri, N., Langley, R. E. & Grabsch, H. I., Jun 2018, In : Histopathology. 72, 7, p. 1180-1188 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Comparing Gene Copy Number Status of Receptor Tyrosine Kinase and Downstream Signalling Genes Between Oesophageal and Gastric Cancer

Slaney, H. L., Hewitt, L. C., Silva, A., Wickstone, C., Davarzani, N., Quirke, P., Hutchins, G. A. & Grabsch, H. I., Sep 2017, In : Journal of Pathology. 243, p. S30-S30 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

MRI for Local Staging of Colon Cancer: Can MRI Become the Optimal Staging Modality for Patients With Colon Cancer?

Nerad, E., Lambregts, D. M. J., Kersten, E. L. J., Maas, M., Bakers, F. C. H., van den Bosch, H. C. M., Grabsch, H. I., Beets-Tan, R. G. H. & Lahaye, M. J., Apr 2017, In : Diseases of the Colon & Rectum. 60, 4, p. 385-392 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neoadjuvant cisplatin and fluorouracil versus epirubicin, cisplatin, and capecitabine followed by resection in patients with oesophageal adenocarcinoma (UK MRC OE05): an open-label, randomised phase 3 trial

Alderson, D., Cunningham, D., Nankivell, M., Blazeby, J. M., Griffin, S. M., Crellin, A., Grabsch, H. I., Langer, R., Pritchard, S., Okines, A., Krysztopik, R., Coxon, F., Thompson, J., Falk, S., Robb, C., Stenning, S. & Langley, R. E., Sep 2017, In : Lancet oncology. 18, 9, p. 1249-1260 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma

Mukherjee, S., Hurt, C. N., Gwynne, S., Sebag-Montefiore, D., Radhakrishna, G., Gollins, S., Hawkins, M., Grabsch, H. I., Jones, G., Falk, S., Sharma, R., Bateman, A., Roy, R., Ray, R., Canham, J., Griffiths, G., Maughan, T. & Crosby, T., Mar 2017, In : European Journal of Cancer. 74, p. 38-46 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Optimising the Sampling Strategy to Determine the Tumour Proportion in the Diagnostic Endoscopic Biopsy in Oesophageal Cancer

Davarzani, N., Hale, M. D., Jolani, S., Hewitt, L. C., Fazzi, G., Hutchins, G. A. & Grabsch, H. I., Sep 2017, In : Journal of Pathology. 243, p. S29-S29 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Peri-operative chemotherapy with or without bevacizumab in operable oesophagogastric adenocarcinoma (UK Medical Research Council ST03): primary analysis results of a multicentre, open-label, randomised phase 2-3 trial

Cunningham, D., Stenning, S. P., Smyth, E. C., Okines, A. F., Allum, W. H., Rowley, S., Stevenson, L., Grabsch, H. I., Alderson, D., Crosby, T., Griffin, S. M., Mansoor, W., Coxon, F. Y., Falk, S. J., Darby, S., Sumpter, K. A., Blazeby, J. M. & Langley, R. E., Mar 2017, In : Lancet oncology. 18, 3, p. 357-370 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016
1 Citation (Scopus)

Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A

Rohwer, N., Bindel, F., Grimm, C., Lin, S. J., Wappler, J., Klinger, B., Bluethgen, N., Du Bois, I., Schmeck, B., Lehrach, H., de Graauw, M., Goncalves, E., Saez-Rodriguez, J., Tan, P., Grabsch, H. I., Prigione, A., Kempa, S. & Cramer, T., 9 Feb 2016, In : Oncotarget. 7, 6, p. 6693-6710

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma - results from the UK MRC OE02 trial

Hale, M. D., Nankivell, M., Hutchins, G. G., Stenning, S. P., Langley, R. E., Mueller, W., West, N. P., Wright, A. I., Treanor, D., Hewitt, L. C., Allum, W. H., Cunningham, D., Hayden, J. D. & Grabsch, H. I., 22 Nov 2016, In : Oncotarget. 7, 47, p. 77565-77575 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Cervical esophageal cancer: a gap in cancer knowledge

Hoeben, A., Polak, J., van de Voorde, L., Hoebers, F., Grabsch, H. I. & de Vos-Geelen, J., Sep 2016, In : Annals of Oncology. 27, 9, p. 1664-1674 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Crossing borders: the key to successful treatment of gastric cancer

Grabsch, H., 8 Jul 2016, Maastricht: [Maastricht University].

Research output: Book/ReportInaugural speechPopular

6 Citations (Scopus)

Effect of Pathologic Tumor Response and Nodal Status on Survival in the Medical Research Council Adjuvant Gastric Infusional Chemotherapy Trial

Smyth, E. C., Fassan, M., Cunningham, D., Allum, W. H., Okines, A. F. C., Lampis, A., Hahne, J. C., Rugge, M., Peckitt, C., Nankivell, M., Langley, R., Ghidini, M., Braconi, C., Wotherspoon, A., Grabsch, H. I. & Valeri, N., 10 Aug 2016, In : Journal of Clinical Oncology. 34, 23, p. 2721-2727 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Five biopsy specimens from the proximal part of the tumor reliably determine HER2 protein expression status in gastric cancer

Tominaga, N., Gotoda, T., Hara, M., Hale, M. D., Tsuchiya, T., Matsubayashi, J., Kono, S., Kusano, C., Itoi, T., Fujimoto, K., Moriyasu, F. & Grabsch, H. I., Apr 2016, In : Gastric Cancer. 19, 2, p. 553-560

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future

van der Post, R. S., Gullo, I., Oliveira, C., H. Tang, L., Grabsch, H., O’Donovan, M., Fitzgerald, R. C., van Krieken, H. & Carneiro, F., 2016, Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract. Jansen, M. & Wright, N. A. (eds.). Springer, p. 371-391 21 p. (Advances in Experimental Medicine and Biology, Vol. 908).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

8 Citations (Scopus)

Immunotherapy in gastrointestinal cancer: Recent results, current studies and future perspectives

Moehler, M., Delic, M., Goepfert, K., Aust, D., Grabsch, H. I., Halama, N., Heinrich, B., Julie, C., Lordick, F., Lutz, M. P., Mauer, M., Alsina Maqueda, M., Schild, H., Schimanski, C. C., Wagner, A-D., Roth, A. & Ducreux, M., May 2016, In : European Journal of Cancer. 59, p. 160-170

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease

Hendrikx, T., Watzenboeck, M. L., Walenbergh, S. M. A., Amir, S., Gruber, S., Kozma, M. O., Grabsch, H. I., Koek, G. H., Pierik, M. J., Staufer, K., Trauner, M., Kalhan, S. C., Jonkers, D., Hofker, M. H., Binder, C. J. & Shiri-Sverdlov, R., 22 Jul 2016, In : BMC Medicine. 14, 13 p., 107.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reduced genomic tumor heterogeneity after neoadjuvant chemotherapy is related to favorable outcome in patients with esophageal adenocarcinoma

Obulkasim, A., Ylstra, B., van Essen, H. F., Benner, C., Stenning, S., Langley, R., Allum, W., Cunningham, D., Inam, I., Hewitt, L. C., West, N. P., Meijer, G. A., van de Wiel, M. A. & Grabsch, H. I., 12 Jul 2016, In : Oncotarget. 7, 28, p. 44084-44095 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

The survival difference between gastric cancer patients from the UK and Japan remains after weighted propensity score analysis considering all background factors

Yamada, T., Yoshikawa, T., Taguri, M., Hayashi, T., Aoyama, T., Sue-Ling, H. M., Bonam, K., Hayden, J. D. & Grabsch, H. I., Apr 2016, In : Gastric Cancer. 19, 2, p. 479-489

Research output: Contribution to journalArticleAcademicpeer-review

2015
7 Citations (Scopus)

Brain metastases in gastro-oesophageal adenocarcinoma: insights into the role of the human epidermal growth factor receptor 2 (HER2)

Feilchenfeldt, J., Varga, Z., Siano, M., Grabsch, H. I., Held, U., Schuknecht, B., Trip, A., Hamaguchi, T., Gut, P., Balague, O., Khanfir, K., Diebold, J., Jochum, W., Shoji, H., Kushima, R., Wagner, D., Shimada, Y., Cats, A., Knuth, A., Moch, H. & 2 others, Aebi, S. & Hofer, S., 1 Sep 2015, In : British Journal of Cancer. 113, 5, p. 716-721

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Endoscopic biopsies from gastrointestinal carcinomas and their suitability for molecular analysis: a review of the literature and recommendations for clinical practice and research

Hale, M. D., Gotoda, T., Hayden, J. D. & Grabsch, H. I., Aug 2015, In : Histopathology. 67, 2, p. 147-157

Research output: Contribution to journalArticleAcademicpeer-review

KRAS, BRAF and gastric cancer

Hewitt, L. C., Hutchins, G. G., Melotte, V., Saito, Y. & Grabsch, H. I., Nov 2015, In : Translational Gastrointestinal Cancer . 4, 6, p. 429-447

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma

Mukherjee, S., Hurt, C. N., Gwynne, S., Bateman, A., Gollins, S., Radhakrishna, G., Hawkins, M., Canham, J., Lewis, W., Grabsch, H. I., Sharma, R. A., Wade, W., Maggs, R., Tranter, B., Roberts, A., Sebag-Montefiore, D., Maughan, T., Griffiths, G. & Crosby, T., 2015, In : BMC Cancer. 15, 48, 9 p., 48.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Smith, A-D., Urquhart, G., Bielawski, J., Finnegan, M. & Petty, R., 22 Oct 2015, In : BMC Cancer. 15, 762.

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas

Lin, S. J., Gagnon-Bartsch, J. A., Tan, I. B., Earle, S., Ruff, L., Pettinger, K., Ylstra, B., van Grieken, N., Rha, S. Y., Chung, H. C., Lee, J-S., Cheong, J. H., Noh, S. H., Aoyama, T., Miyagi, Y., Tsuburaya, A., Yoshikawa, T., Ajani, J. A., Boussioutas, A., Yeoh, K. G. & 11 others, Yong, W. P., So, J., Lee, J., Kang, W. K., Kim, S., Kameda, Y., Arai, T., zur Hausen, A., Speed, T. P., Grabsch, H. I. & Tan, P., Nov 2015, In : Gut. 64, 11, p. 1721-1731

Research output: Contribution to journalArticleAcademicpeer-review

2014
7 Citations (Scopus)

High-level copy number gains of established and potential drug target genes in gastric cancer as a lead for treatment development and selection

Labots, M., Buffart, T. E., Haan, J. C., van Grieken, N. C. T., Tijssen, M., van de Velde, C. J. H., Grabsch, H. I., Ylstra, B., Carvalho, B., Fijneman, R. J. A., Verheul, H. M. W. & Meijer, G. A., Feb 2014, In : Cellular oncology. 37, 1, p. 41-52 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

2012

Chromosome 5q Loss in Colorectal Flat Adenomas

Voorham, Q. J. M., Carvalho, B., Spiertz, A. J., van Grieken, N. C. T., Mongera, S., Rondagh, E. J. A., van de Wiel, M. A., Jordanova, E. S., Ylstra, B., Kliment, M., Grabsch, H., Rembacken, B. J., Arai, T., de Bruine, A. P., Sanduleanu, S., Quirke, P., Mulder, C. J. J., van Engeland, M. & Meijer, G. A., 1 Sep 2012, In : Clinical Cancer Research. 18, 17, p. 4560-4569

Research output: Contribution to journalArticleAcademicpeer-review

Comprehensive Mutation Analysis in Colorectal Flat Adenomas

Voorham, Q. J. M., Carvalho, B., Spiertz, A. J., Claes, B., Mongera, S., van Grieken, N. C. T., Grabsch, H., Kliment, M., Rembacken, B., van de Wiel, M. A., Quirke, P., Mulder, C. J. J., Lambrechts, D., van Engeland, M. & Meijer, G. A., 27 Jul 2012, In : PLOS ONE. 7, 7, e41963.

Research output: Contribution to journalArticleAcademicpeer-review