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Harry Steinbusch

Dr.

19992020

Research output per year

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Research Output

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Article
2020

Statistical differences resulting from selection of stable reference genes after hypoxia and hypothermia in the neonatal rat brain

Bustelo, M., Bruno, M. A., Loidl, C. F., Rey-Funes, M., Steinbusch, H. W. M., Gavilanes, A. W. D. & van den Hove, D. L. A., 21 May 2020, In : PLOS ONE. 15, 5, 12 p., 0233387.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Study of the Link Between Neuronal Death, Glial Response, and MAPK Pathway in Old Parkinsonian Mice

Luisa Gil-Martinez, A., Cuenca-Bermejo, L., Gallo-Soljancic, P., Sanchez-Rodrigo, C., Izura, V., Steinbusch, H. W. M., Fernandez-Villalba, E. & Trinidad Herrero, M., 29 Jul 2020, In : Frontiers in Aging Neuroscience. 12, 9 p., 214.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019

5-HTT independent effects of fluoxetine on neuroplasticity

Levy, M. J. F., Boulle, F., Emerit, M. B., Poilbout, C., Steinbusch, H. W. M., Van den Hove, D. L. A., Kenis, G. & Lanfumey, L., 19 Apr 2019, In : Scientific Reports. 9, 11 p., 6311.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cerebrospinal Fluid from Patients with Sporadic Amyotrophic Lateral Sclerosis Induces Degeneration of Motor Neurons Derived from Human Embryonic Stem Cells

Sumitha, R., Manjunatha, V. M., Sabitha, R. K., Alladi, P. A., Nalini, A., Rao, L. T., Sagar, B. K. C., Steinbusch, H. W. M., Kramer, B. W., Sathyaprabha, T. N. & Raju, T. R., Feb 2019, In : Molecular Neurobiology. 56, 2, p. 1014-1034 21 p.

Research output: Contribution to journalArticleAcademicpeer-review

Distribution of neuronal nitric oxide synthase immunoreactivity in adult male Sprague-Dawley rat brain

Chong, P. S., Poon, C. H., Fung, M. L., Guan, L., Steinbusch, H. W. M., Chan, Y-S., Lim, W. L. & Lim, L. W., Nov 2019, In : Acta Histochemica. 121, 8, 22 p., 151437.

Research output: Contribution to journalArticleAcademicpeer-review

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala

Weidner, M. T., Lardenoije, R., Eijssen, L., Mogavero, F., De Groodt, L. P. M. T., Popp, S., Palme, R., Foerstner, K. U., Strekalova, T., Steinbusch, H. W. M., Schmitt-Boehrer, A. G., Glennon, J. C., Waider, J., van den Hove, D. L. A. & Lesch, K-P., 10 May 2019, In : Frontiers in Neuroscience. 13, 17 p., 460.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Systemic multipotent adult progenitor cells improve long-term neurodevelopmental outcomes after preterm hypoxic-ischemic encephalopathy

Barkhuizen, M., van Mechelen, R., Vermeer, M., Chedraui, P., Paes, D., van den Hove, D. L. A., Vaes, B., Mays, R. W., Steinbusch, H. W. M., Robertson, N. J., Kramer, B. W. & Gavilanes, A. W. D., 19 Apr 2019, In : Behavioural Brain Research. 362, p. 77-81 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Transiently proliferating perivascular microglia harbor M1 type and precede cerebrovascular changes in a chronic hypertension model

Koizumi, T., Taguchi, K., Mizuta, I., Toba, H., Ohigashi, M., Onishi, O., Ikoma, K., Miyata, S., Nakata, T., Tanaka, M., Foulquier, S., Steinbusch, H. W. M. & Mizuno, T., 10 Apr 2019, In : Journal of Neuroinflammation. 16, 13 p., 79.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Gestational stress in mouse dams negatively affects gestation and postpartum hippocampal BDNF and P11 protein levels

Vanmierlo, T., De Vry, J., Nelissen, E., Sierksma, A., Roumans, N., Steinbusch, H. W. M., Wennogle, L. P., van den Hove, D. & Prickaerts, J., 1 Apr 2018, In : Molecular and Cellular Neuroscience. 88, p. 292-299 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Glutamatergic cells in the periaqueductal gray matter mediate sensory inputs after bladder stimulation in freely moving rats

Zare, A., Jahanshahi, A., Meriaux, C., Steinbusch, H. W. M. & van Koeveringe, G. A., 1 Jun 2018, In : International Journal of Urology. 25, 6, p. 621-626 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model

Verheijen, B. M., Stevens, J. A. A., Gentier, R. J. G., van't Hekke, C. D., van den Hove, D. L. A., Hermes, D. J. H. P., Steinbusch, H. W. M., Ruijter, J. M., Grimm, M. O. W., Haupenthal, V. J., Annaert, W., Hartmann, T. & van Leeuwen, F. W., 1 Dec 2018, In : Neurobiology of Aging. 72, p. 62-71 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb

Barkhuizen, M., van Dijck, F. J. P., Jellema, R. K., Gussenhoven, R., Engelbertink, I., van Mechele, R., Cleutjens, J. P. M., Seehase, M., Steinbusch, H. W. M., Zimmerman, L. J., Gavilanes, A. W. D. & Kramer, B. W., 1 Jun 2018, In : Pediatric Research. 83, 6, p. 1190-1199 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017
101 Downloads (Pure)

An in vitro and in vivo study of peptide-functionalized nanoparticles for brain targeting: The importance of selective blood-brain barrier uptake

Bode, G. H., Coue, G., Freese, C., Pickl, K. E., Sanchez-Purra, M., Albaiges, B., Borros, S., van Winden, E. C., Tziveleka, L-A., Sideratou, Z., Engbersen, J. F. J., Singh, S., Albrecht, K., Groll, J., Moeller, M., Poetgens, A. J. G., Schmitzk, C., Froehlich, E., Grandfils, C., Sinner, F. M. & 5 others, Kirkpatrick, C. J., Steinbusch, H. W. M., Frank, H-G., Unger, R. E. & Martinez-Martinez, P., Apr 2017, In : Nanomedicine-Nanotechnology Biology and Medicine. 13, 3, p. 1289-1300 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cerebral and Retinal Neurovascular Changes: A Biomarker for Alzheimer’s Disease

Karru Venkata Ravi, T., Berendschot, T. T. J. M., Steinbusch, H. W. M., Webers, C. A. B., Praveen Murthy, R. & Mathuranath, P. S., 2017, In : Journal of Gerontology & Geriatric Research. 6, -, p. 447 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Early stages of Alzheimer's disease are alarming signs in injury deaths caused by traffic accidents in elderly people (>= 60 years of age): A neuropathological study

Wijesinghe, P., Gorrie, C., Shankar, S. K., Chickabasaviah, Y. T., Amaratunga, D., Hulathduwa, S., Kumara, K. S., Samarasinghe, K., Suh, Y-H., Steinbusch, H. W. M. & De Silva, K. R. D., 2017, In : Indian Journal of Psychiatry. 59, 4, p. 471-477 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Nitric Oxide Production in the Striatum and Cerebellum of a Rat Model of Preterm Global Perinatal Asphyxia

Barkhuizen, M., Van de Berg, W. D. J., De Vente, J., Blanco, C. E., Gavilanes, A. W. D. & Steinbusch, H. W. M., Apr 2017, In : Neurotoxicity Research. 31, 3, p. 400-409 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

On the Role of DT-Diaphorase Inhibition in Aminochrome-Induced Neurotoxicity In Vivo

Herrera-Soto, A., Diaz-Veliz, G., Mora, S., Munoz, P., Henny, P., Steinbusch, H. W. M. & Segura-Aguilar, J., Jul 2017, In : Neurotoxicity Research. 32, 1, p. 134-140 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The olfactory bulbectomized rat model is not an appropriate model for studying depression based on morphological/stereological studies of the hippocampus

Yurttas, C., Schmitz, C., Turgut, M., Strekalova, T. & Steinbusch, H. W. M., Sep 2017, In : Brain Research Bulletin. 134, p. 128-135 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The phosphodiesterase type 2 inhibitor BAY 60-7550 reverses functional impairments induced by brain ischemia by decreasing hippocampal neurodegeneration and enhancing hippocampal neuronal plasticity

Soares, L. M., Meyer, E., Milani, H., Steinbusch, H. W. M., Prickaerts, J. & de Oliveira, R. M. W., Feb 2017, In : European Journal of Neuroscience. 45, 4, p. 510-520 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Aminochrome induces dopaminergic neuronal dysfunction: a new animal model for Parkinson's disease

Herrera, A., Munoz, P., Paris, I., Diaz-Veliz, G., Mora, S., Inzunza, J., Hultenby, K., Cardenas, C., Jana, F., Raisman-Vozari, R., Gysling, K., Abarca, J., Steinbusch, H. W. M. & Segura-Aguilar, J., Sep 2016, In : Cellular and Molecular Life Sciences. 73, 18, p. 3583-3597

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Behavioral and neurochemical characterization of Tr kappa B-dependent mechanisms of agomelatine in glucocorticoid receptor-impaired mice

Boulle, F., Velthuis, H., Koedam, K., Steinbusch, H. W., van den Hove, D. L. A., Kenis, G., Gabriel, C., Mocaer, E., Franc, B., Rognan, D., Mongeau, R. & Lanfumey, L., Jan 2016, In : European Neuropsychopharmacology. 26, 1, p. 65-77

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Characterisation of cell-substrate interactions between Schwann cells and three-dimensional fibrin hydrogels containing orientated nanofibre topographical cues

Hodde, D., Gerardo-Nava, J., Woehlk, V., Weinandy, S., Jockenhoevel, S., Kriebel, A., Altinova, H., Steinbusch, H. W. M., Moeller, M., Weis, J., Mey, J. & Brook, G. A., Feb 2016, In : European Journal of Neuroscience. 43, 3, p. 376-387

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

CO2 exposure as translational cross-species experimental model for panic

Leibold, N. K., van den Hove, D. L. A., Viechtbauer, W., Buchanan, G. F., Goossens, L., Lange, I., Knuts, I., Lesch, K. P., Steinbusch, H. W. M. & Schruers, K. R. J., 6 Sep 2016, In : Translational Psychiatry. 6, e885.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Cytoskeletal Pathologies of Age-Related Diseases between Elderly Sri Lankan (Colombo) and Indian (Bangalore) Brain Samples

Wijesinghe, P., Shankar, S. K., Chickabasaviah, Y. T., Gorrie, C., Amaratunga, D., Hulathduwa, S., Kumara, K. S., Samarasinghe, K., Suh, Y. H., Steinbusch, H. W. & De Silva, K. R. D., 2016, In : Current Alzheimer Research. 13, 3, p. 268-280

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Developmental fluoxetine and prenatal stress effects on serotonin, dopamine, and synaptophysin density in the PFC and hippocampus of offspring at weaning

Gemmel, M., Rayen, I., Lotus, T., van Donkelaar, E., Steinbusch, H., De Lacalle, S., Kokras, N., Dalla, C. & Pawluski, J. L., Apr 2016, In : Developmental Psychobiology. 58, 3, p. 315-327 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Developmental fluoxetine exposure increases behavioral despair and alters epigenetic regulation of the hippocampal BDNF gene in adult female offspring

Boulle, F., Pawluski, J. L., Homberg, J. R., Machiels, B., Kroeze, Y., Kumar, N., Steinbusch, H. W. M., Kenis, G. & van den Hove, D. L. A., Apr 2016, In : Hormones and Behavior. 80, p. 47-57

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Effects of prenatal Poly I:C exposure on global histone deacetylase (HDAC) and DNA methyltransferase (DNMT) activity in the mouse brain

Lopez, Y. P., Kenis, G., Stettinger, W., Neumeier, K., de Jonge, S., Steinbusch, H. W. M., Zill, P., van den Hove, D. L. A. & Myint, A. M., Jul 2016, In : Molecular Biology Reports. 43, 7, p. 711-717

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fluoxetine Treatment Induces Seizure Behavior and Premature Death in APPswe/PS1dE9 Mice

Sierksma, A. S. R., de Nijs, L., Hoogland, G., Vanmierlo, T., van Leeuwen, F. W., Rutten, B. P. F., Steinbusch, H. W. M., Prickaerts, J. & van den Hove, D. L. A., 2016, In : Journal of Alzheimer's Disease. 51, 3, p. 677-682

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Gestational stress and fluoxetine treatment differentially affect plasticity, methylation and serotonin levels in the PFC and hippocampus of rat dams

Gemmel, M., Rayen, I., van Donkelaar, E., Loftus, T., Steinbusch, H., Kokras, N., Dalla, C. & Pawluski, J. L., 7 Jul 2016, In : Neuroscience. 327, p. 32-43 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test

Strekalova, T., Markova, N., Shevtsova, E., Zubareva, O., Bakhmet, A., Steinbusch, H. M., Bachurin, S. & Lesch, K-P., 2016, In : Neural Plasticity. 2016, 5098591.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Insulin receptor sensitizer, dicholine succinate, prevents both Toll-like receptor 4 (TLR4) upregulation and affective changes induced by a high-cholesterol diet in mice

Strekalova, T., Costa-Nunes, J. P., Veniaminova, E., Kubatiev, A., Lesch, K-P., Chekhonin, V. P., Evans, M. C. & Steinbusch, H. W. M., 15 May 2016, In : Journal of Affective Disorders. 196, p. 109-116

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Low-dose lipopolysaccharide (LPS) inhibits aggressive and augments depressive behaviours in a chronic mild stress model in mice

Couch, Y., Trofimov, A., Markova, N., Nikolenko, V., Steinbusch, H. W., Chekhonin, V., Schroeter, C., Lesch, K-P., Anthony, D. C. & Strekalova, T., 16 May 2016, In : Journal of Neuroinflammation. 13, 108.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology

Bardy, C., van den Hurk, M., Kakaradov, B., Erwin, J. A., Jaeger, B. N., Hernandez, R. V., Eames, T., Paucar, A. A., Gorris, M., Marchand, C., Jappelli, R., Barron, J., Bryant, A. K., Kellogg, M., Lasken, R. S., Rutten, B. P. F., Steinbusch, H. W. M., Yeo, G. W. & Gage, F. H., Nov 2016, In : Molecular Psychiatry. 21, 11, p. 1573-1588

Research output: Contribution to journalArticleAcademicpeer-review

Prenatal stress and early-life exposure to fluoxetine have enduring effects on anxiety and hippocampal BDNF gene expression in adult male offspring

Boulle, F., Pawluski, J. L., Homberg, J. R., Machiels, B., Kroeze, Y., Kumar, N., Steinbusch, H. W. M., Kenis, G. & Van den Hove, D. L. A., May 2016, In : Developmental Psychobiology. 58, 4, p. 427-438

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Quinolinic acid-immunoreactivity in the naive mouse brain

Lopez, Y. P., Kenis, G., Rutten, B. P. F., Myint, A. M., Steinbusch, H. W. M. & van den Hove, D. L. A., Jan 2016, In : Journal of Chemical Neuroanatomy. 71, p. 6-12

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

ROLIPRAM IMPROVES COGNITION, REDUCES ANXIETY- AND DESPAIR-LIKE BEHAVIORS AND IMPACTS HIPPOCAMPAL NEUROPLASTICITY AFTER TRANSIENT GLOBAL CEREBRAL ISCHEMIA

Soares, L. M., De Vry, J., Steinbusch, H. W. M., Milani, H., Prickaerts, J. & Weffort De Oliveira, R. M., 21 Jun 2016, In : Neuroscience. 326, p. 69-83

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Transcriptional and epigenetic mechanisms of cellular reprogramming to induced pluripotency

van den Hurk, M., Kenis, G., Bardy, C., van den Hove, D. L., Gage, F. H., Steinbusch, H. W. & Rutten, B. P., Aug 2016, In : Epigenomics. 8, 8, p. 1131-1149

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

TrkB in the hippocampus and nucleus accumbens differentially modulates depression-like behavior in mice

De Vry, J., Vanmierlo, T., Martinez-Martinez, P., Losen, M., Temel, Y., Boere, J., Kenis, G., Steckler, T., Steinbusch, H. W. M., De Baets, M. & Prickaerts, J., 1 Jan 2016, In : Behavioural Brain Research. 296, p. 15-25

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Vascular Contributions in Alzheimer's Disease-Related Neuropathological Changes: First Autopsy Evidence from a South Asian Aging Population

Wijesinghe, P., Shankar, S. K., Yasha, T. C., Gorrie, C., Amaratunga, D., Hulathduwa, S., Kumara, K. S., Samarasinghe, K., Suh, Y., Steinbusch, H. W. M. & De Silva, K. R. D., 2016, In : Journal of Alzheimer's Disease. 54, 4, p. 1607-1618

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)
2015

Animal Models of Depression and Drug Delivery with Food as an Effective Dosing Method: Evidences from Studies with Celecoxib and Dicholine Succinate

Costa-Nunes, J. P., Cline, B. H., Araujo-Correia, M., Valenca, A., Markova, N., Dolgov, O., Kubatiev, A., Yeritsyan, N., Steinbusch, H. W. M. & Strekalova, T., 2015, In : BioMed Research International. 596126.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Defeat stress in rodents: From behavior to molecules

Hammels, C., Pishva, E., De Vry, J., van den Hove, D. L. A., Prickaerts, J., van Winkel, R., Selten, J-P., Lesch, K-P., Daskalakis, N. P., Steinbusch, H. W. M., van Os, J., Kenis, G. & Rutten, B. P. F., Dec 2015, In : Neuroscience and Biobehavioral Reviews. 59, p. 111-40 30 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Detection of Peptide-Based Nanoparticles in Blood Plasma by ELISA

Bode, G. H., Pickl, K. E., Sanchez-Purra, M., Albaiges, B., Borros, S., Poetgens, A. J. G., Schmitz, C., Sinner, F. M., Losen, M., Steinbusch, H. W. M., Frank, H-G. & Martinez-Martinez, P., 21 May 2015, In : PLOS ONE. 10, 5, e0126136.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Deuterium content of water increases depression susceptibility: The potential role of a serotonin-related mechanism

Strekalova, T., Evans, M., Chernopiatko, A., Couch, Y., Costa-Nunes, J., Cespuglio, R., Chesson, L., Vignisse, J., Steinbusch, H. W., Anthony, D. C., Pomytkin, I. & Lesch, K-P., 15 Jan 2015, In : Behavioural Brain Research. 277, p. 237-244

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Developmental exposure to SSRIs, in addition to maternal stress, has long-term sex-dependent effects on hippocampal plasticity

Rayen, I., Gemmel, M., Pauley, G., Steinbusch, H. W. M. & Pawluski, J. L., Apr 2015, In : Psychopharmacology. 232, 7, p. 1231-1244

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Dicholine succinate, the neuronal insulin sensitizer, normalizes behavior, REM sleep, hippocampal pGSK3 beta and niRNAs of NMDA receptor subunits in mouse models of depression

Cline, B. H., Costa-Nunes, J. P., Cespuglio, R., Markova, N., Santos, A. I., Bukhman, Y. V., Kubatiev, A., Steinbusch, H. W. M., Lesch, K-P. & Strekalova, T., 26 Feb 2015, In : Frontiers in Behavioral Neuroscience. 9, 37.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)
5 Citations (Scopus)

DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts

Chouliaras, L., Kenis, G., Visser, P. J., Scheltens, P., Tsolaki, M., Jones, R. W., Kehoe, P. G., Graff, C., Girtler, N. G., Wallin, A. K., Rikkert, M. O., Spiru, L., Elias-Sonnenschein, L. S., Ramakers, I. H. G. B., Pishva, E., van Os, J., Steinbusch, H. W. M., Verhey, F. R. J., van den Hove, D. L. A. & Rutten, B. P. F., 2015, In : Epigenomics. 7, 4, p. 533-537

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)