20002018

Research output per year

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2018

Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 alpha increase in epidermal in vitro model

Zanoni, T. B., Pedrosa, T. N., Catarino, C. M., Spiekstra, S. W., de Oliveira, D. P., Den Hartog, G., Bast, A., Hagemann, G., Gibbs, S., de Moraes Barros, S. B. & Maria-Engler, S. S., Feb 2018, In : Food and Chemical Toxicology. 112, p. 265-272 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipase diffusion in oil-filled, alginate micro- and macrobeads

van Leusden, P., den Hartog, G. J. M., Bast, A., Postema, M., van der Linden, E. & Sagis, L. M. C., 1 Dec 2018, In : Food Hydrocolloids. 85, p. 242-247 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The chemical reactivity of (-)-epicatechin quinone mainly resides in its Bring

Zhang, M., Vervoort, L., Moalin, M., Mommers, A., Douny, C., den Hartog, G. J. M. & Haenen, G. R. M. M., 20 Aug 2018, In : Free Radical Biology and Medicine. 124, p. 31-39 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The contribution of alpha-dicarbonyl compound dependent radical formation to the antiseptic effect of honey

Henatsch, D., den Hartog, G. J. M., Duijvestijn, A. M., Wolffs, P. F., Phielix, E., Stokroos, R. J. & Briede, J. J., Jun 2018, In : Journal of Functional Foods. 45, p. 239-246 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017
Open Access

Permeation of probe molecules into alginate microbeads: Effect of salt and processing

van Leusden, P., den Hartog, G. J. M., Bast, A., Postema, M., van der Linden, E. & Sagis, L. M. C., Dec 2017, In : Food Hydrocolloids. 73, p. 255-261 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Strength of microbeads for the encapsulation of heat sensitive, hydrophobic components

van Leusden, P., den Hartog, G. J. M., Bast, A., Postema, M., van der Linden, E. & Sagis, L. M. C., May 2016, In : Food Hydrocolloids. 56, p. 318-324

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Structure engineering of filled protein microbeads to tailor release of oil droplets in gastric digestion

van Leusden, P., den Hartog, G. J. M., Bast, A., Postema, M., van der Linden, E. & Sagis, L. M. C., 1 Aug 2016, In : Food & Function. 7, 8, p. 3539-3547

Research output: Contribution to journalArticleAcademicpeer-review

2015

Exhaled Biomarkers and Gene Expression at Preschool Age Improve Asthma Prediction at 6 Years of Age

Klaassen, E. M. M., van de Kant, K. D. G., Jöbsis, Q., van Schayck, O. C. P., Smolinska, A., Dallinga, J. W., van Schooten, F. J., den Hartog, G. J. M., de Jongste, J. C., Rijkers, G. T. & Dompeling, E., 15 Jan 2015, In : American Journal of Respiratory and Critical Care Medicine. 191, 2, p. 201-207 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Health effects of erythritol

Boesten, D. M. P. H. J., den Hartog, G. J. M., de Cock, P., Bosscher, D., Bonnema, A. & Bast, A., 1 Jan 2015, In : Nutrafoods. 14, p. 3-9

Research output: Contribution to journalArticleAcademicpeer-review

Protective Pleiotropic Effect of Flavonoids on NAD(+) Levels in Endothelial Cells Exposed to High Glucose

Boesten, D. M., von Ungern-Sternberg, S. N., den Hartog, G. J. & Bast, A., 1 Jan 2015, In : Oxidative Medicine and Cellular Longevity. 2015, 894597.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
2014

Effect of Nɛ-carboxymethyllysine on oxidative stress and the glutathione system in beta cells

Boesten, D. M. P. H. J., Elie, A. G. I. M., Dritty-Reijnders, M. J. H. J., den Hartog, G. J. M. & Bast, A., 1 Jan 2014, In : Toxicology Reports. 1, p. 973-980

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Integrative genomic analysis identifies a role for intercellular adhesion molecule 1 in childhood asthma

Klaassen, E. M. M., van de Kant, K. D. G., Jöbsis, Q., Penders, J., van Schooten, F. J., Quaak, M., den Hartog, G. J. M., Koppelman, G. H., van Schayck, C. P., van Eys, G. & Dompeling, E., 1 Jan 2014, In : Pediatric Allergy and Immunology. 25, 2, p. 166-172

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Superoxide anion radicals activate hepatic stellate cells after entry through chloride channels: A new target in liver fibrosis

den Hartog, G. J., Qi, S., van Tilburg, J. H., Koek, G. H. & Bast, A., 5 Feb 2014, In : European Journal of Pharmacology. 724, 5 February, p. 140-144 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
2013

Accelerated aging during chronic oxidative stress: a role for PARP-1

Boesten, D. M., de Vos-Houben, J. M., Timmermans, L., den Hartog, G. J., Bast, A. & Hageman, G. J., 1 Jan 2013, In : Oxidative Medicine and Cellular Longevity. 2013, 10 p., 680414.

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Elevated citrate levels in non-alcoholic fatty liver disease: The potential of citrate to promote radical production

van de Wier, B., Balk, J. M., Haenen, G. R. M. M., Giamouridis, D., Bakker, J. A., Bast, B. C., den Hartog, G. J. M., Koek, G. H. & Bast, A., 2 Aug 2013, In : Febs Letters. 587, 15, p. 2461-2466 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Multi-targeted mechanisms underlying the endothelial protective effects of the diabetic-safe sweetener erythritol

Boesten, D. M., Berger, A., de Cock, P., Dong, H., Hammock, B. D., den Hartog, G. J. M. & Bast, A., 5 Jun 2013, In : PLOS ONE. 8, 6, 12 p., e65741.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Oxyphytosterol formation in humans: Identification of high vs. low oxidizers.

Baumgartner, S., Mensink, R. P., den Hartog, G. J., Bast, A., Bekers, O., Husche, C., Lutjohann, D. & Plat, J., 1 Jan 2013, In : Biochemical Pharmacology. 86, 1, p. 19-25

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Redox Modulation by Amaranth Oil in Human Lung Fibroblasts

Semen, K. O., den Hartog, G. J. M., Kaminsky, D. V., Sirota, T. V., Maij, N. G. A. A., Yelisyeyeva, O. P. & Bast, A., 1 Jan 2013, In : Natural Products Chemistry & Research. December, 2013

Research output: Contribution to journalArticleAcademicpeer-review

Zoet in de strijd tegen suiker

Bast, A., den Hartog, G. J. & Boesten, D. M., 26 Jun 2013, In : Dagblad de Limburger - Limburgs Dagblad. 2 p.

Research output: Contribution to journalArticlePopular

Open Access
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103 Downloads (Pure)
2012

Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice.

Paglialunga, S., van Bree, B. W., Bosma, M., Valdecantos, M. P., Amengual Cladera, E., Jorgensen, J. A., Van Beurden, D., den Hartog, G. J. M., Ouwens, DM., Briedé, J. J., Schrauwen, P. & Hoeks, J., Oct 2012, In : Diabetologia. 55, 10, p. 2759-2768 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)
2011

Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-({beta}-hydroxyethyl)-rutoside in Mice.

Jacobs, H., Peters, R., den Hartog, G. J. M., van der Vijgh, W. J. F., Bast, A. & Haenen, G. R. M. M., 1 Jan 2011, In : Drug Metabolism and Disposition. 39, 5, p. 750-756

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
2010

Erythritol is a sweet antioxidant

den Hartog, G. J., Boots, A. W., Adam Perrot, A., Brouns, F. J. P. H., Verkooijen, I. W., Weseler, A. R., Haenen, G. R. & Bast, A., 1 Jan 2010, In : Nutrition. 26, 4, p. 449-458

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Oxidative stress and antioxidants in interstitial lung disease.

Bast, A., Weseler, A. R., Haenen, G. R. M. M. & den Hartog, G. J. M., 1 Jan 2010, In : Current Opinion in Pulmonary Medicine. 16, 5, p. 516-520

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)
2009

Partial bladder outlet obstruction reduces the tissue antioxidant capacity and muscle nerve density of the guinea pig bladder

de Jongh, R., Dambros, M., Haenen, G. R., den Hartog, G. J., Bast, A., van Kerrebroeck, P. E. & van Koeveringe, G. A., Jun 2009, In : Neurourology and Urodynamics. 28, 5, p. 461-467

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)
31 Citations (Scopus)
2008

Biomarker reproducibility in exhaled breath condensate collected with different condensers

Rosias, P. P., Robroeks, C. M., Kester, A., den Hartog, G. J., Wodzig, W. K., Rijkers, G. T., Zimmermann, L. J., van Schayck, C. P., Jöbsis, Q. & Dompeling, E. D., 1 Jan 2008, In : European Respiratory Journal. 31, 5, p. 934-42

Research output: Contribution to journalArticleAcademicpeer-review

53 Citations (Scopus)

Biomarkers in exhaled breath condensate indicate presence and severity of cystic fibrosis in children

Robroeks, C. M., Rosias, P. P., van Vliet, D., Jöbsis, Q., Yntema, J. B., Brackel, H. J., Damoiseaux, J. G. M. C., den Hartog, G. J. M., Wodzig, W. K. & Dompeling, E. D., 1 Jan 2008, In : Pediatric Allergy and Immunology. 19, 7, p. 652-9

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)
2007

New iron chelators in anthracycline-induced cardiotoxicity.

Kaiserova, H., Simunek, T., Sterba, M., den Hartog, G. J., Schroterova, L., Popelova, O., Gersl, V., Kvasnickova, E. & Bast, A., 1 Jan 2007, In : Cardiovascular Toxicology. 7, 2, p. 145-150

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Protectors against doxorubicin-induced cardiotoxicity: Flavonoids

Bast, A., Kaiserova, H., den Hartog, G. J., Haenen, G. R. & van der Vijgh, W. J., 1 Jan 2007, In : Cell Biology and Toxicology. 23, 1, p. 39-47

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)
2006

Free radicals in exhaled breath condensate in cystic fibrosis and healthy subjects

Rosias, P. P. R., den Hartog, G. J., Robroeks, C. M., Bast, A., Donckerwolcke, R. A., Heynens, J. W., Suykerbuyk, J., Hendriks, H. J., Jöbsis, Q. & Dompeling, E. D., 1 Jan 2006, In : Free Radical Research. 40, 9, p. 901-909

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin

Kaiserova, H., den Hartog, G. J., Simunek, T., Schroterova, L., Kvasnickova, E. & Bast, A., 1 Jan 2006, In : British Journal of Pharmacology. 149, 7, p. 920-930

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)
2004

Lecithinized copper,zinc-superoxide dismutase as a protector against doxorubicin-induced cardiotoxicity in mice

den Hartog, G. J. M., Haenen, G. R. M. M., Boven, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2004, In : Toxicology and Applied Pharmacology. 194, 2, p. 180-188 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)
2003

Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin

den Hartog, G. J. M., Boots, A. W., Haenen, G. R. M. M., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : Toxicology in Vitro. 17, 2, p. 165-167 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Superoxide dismutase: the balance between prevention and induction of oxidative damage

den Hartog, G. J. M., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : Chemico-Biological Interactions. 145, 1, p. 33-39 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)
2002

Efficacy of HOCI scavenging by sulfurcontaining compounds: antioxidant activity of glutathione disulfide?

den Hartog, G. J., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2002, In : Biological Chemistry. 383, p. 709-713

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of HOCl scavenging by sulfur-containing compounds: antioxidant activity of glutathione disulfide?

den Hartog, G. J. M., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2002, In : Biological Chemistry. 383, 3-4, p. 709-713 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hypochlorous acid is a potent inhibitor of acetylcholinesterase

den Hartog, G. J. M., Vegt, E., van der Vijgh, W. J. F., Haenen, G. R. M. M. & Bast, A., 1 Jan 2002, In : Toxicology and Applied Pharmacology. 181, 3, p. 228-232 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
36 Citations (Scopus)
2001

Ambient particulate matter induces relaxation of rat aortic rings in vitro.

Knaapen, A. M., den Hartog, G. J. M., Bast, A. & Borm, P. J. A., 1 Jan 2001, In : Human & Experimental Toxicology. 20, 5, p. 259-265 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Hypochlorous acid is a potent inhibitor of GST P1-1.

van Haaften, R. I. M., den Hartog, G. J. M., Evelo, C. T. A., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Chemico-Biological Interactions. 138, p. 77-83 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)
2000

Inhibition of nitric oxide synthase by nasal decongestants

Westerveld, G. J., Voss, H. P., van der Hee, R. M., de Haan-Koelewijn, G. J. N., den Hartog, G. J. M., Scheeren, R. A. & Bast, A., 1 Jan 2000, In : European Respiratory Journal. 16, p. 437-444 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)