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Research Output 1989 2019

2019

Bortezomib-based induction followed by stem cell transplantation in light chain amyloidosis: results of the multicenter HOVON 104 trial

Minnema, M. C., Nasserinejad, K., Hazenberg, B., Hegenbart, U., Vlummens, P., Ypma, P. F., Kroeger, N., Wu, K. L., Kersten, M. J., Schaafsma, M. R., Croockewit, S., de Waal, E., Zweegman, S., Tick, L., Broijl, A., Koene, H., Bos, G., Sonneveld, P. & Schoenland, S., 30 Oct 2019, In : Haematologica-the Hematology Journal. 104, 11, p. 2274-2282 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Characterization of BAT activity in rats using invasive and non-invasive techniques

Paulus, A., van Ewijk, P. A., Nascimento, E. B. M., De Saint-Hubert, M., Hendrikx, G., Vogg, A., Pooters, I., Schnijderberg, M., Vanderlocht, J., Bos, G., Brans, B., Schrauwen-Hinderling, V. B., Mottaghy, F. M. & Bauwens, M., 15 May 2019, In : PLOS ONE. 14, 5, p. 1-18 18 p., 0215852.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Developing a patient portal for haematology patients requires involvement of all stakeholders and a customised design, tailored to the individual needs

Geerts, P. A. F., van der Weijden, T., Loeffen, P. G. M., Janssen, L. E. F., Almekinders, C., Wienhold, T. A. & Bos, G. M. J., 11 Jul 2019, In : BMC Medical Informatics and Decision Making. 19, 10 p., 129.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review

van Gorkom, G. N. Y., Lookermans, E. L., Van Elssen, C. H. M. J. & Bos, G. M. J., May 2019, In : Nutrients. 11, 5, 15 p., 977.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2018

A comprehensive overview of FCGR3A gene variability by full-length gene sequencing including the identification of V158F polymorphism

Mahaweni, N. M., Olieslagers, T. I., Rivas, I. O., Molenbroeck, S. J. J., Groeneweg, M., Bos, G. M. J., Tilanus, M. G. J., Voorter, C. E. M. & Wieten, L., 29 Oct 2018, In : Scientific Reports. 8, 11 p., 15983.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Bortezomib before and after high-dose therapy in myeloma: long-term results from the phase III HOVON-65/GMMGHD-4 trial

Goldschmidt, H., Lokhorst, H. M., Mai, E. K., van der Holt, B., Blau, I. W., Zweegman, S., Weisel, K. C., Vellenga, E., Pfreundschuh, M., Kersten, M. J., Scheid, C., Croockewit, S., Raymakers, R., Hose, D., Potamianou, A., Jauch, A., Hillengass, J., Stevens-Kroef, M., Raab, M. S., Broijl, A. & 12 others, Lindemann, H. W., Bos, G. M. J., Brossart, P., Kooy, M. V. M., Ypma, P., Duehrsen, U., Schaafsma, R. M., Bertsch, U., Hielscher, T., Jarari, L., Salwender, H. J. & Sonneveld, P., 1 Feb 2018, In : Leukemia. 32, 2, p. 383-390 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cereblon loss and up-regulation of c-Myc are associated with lenalidomide resistance in multiple myeloma patients

Franssen, L. E., Nijhof, I. S., Couto, S., Levin, M-D., Bos, G. M. J., Broijl, A., Klein, S. K., Ren, Y., Wang, M., Koene, H. R., Bloem, A. C., Beeker, A., Faber, L. M., van der Spek, E., Raymakers, R., Leguit, R. J., Sonneveld, P., Zweegman, S., Lokhorst, H., Mutis, T. & 3 others, Thakurta, A., Qian, X. & van de Donk, N. W. C. J., 31 Jul 2018, In : Haematologica-the Hematology Journal. 103, 8, p. E368-E371 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access

Daratumumab augments alloreactive natural killer cell cytotoxicity towards CD38+multiple myeloma cell lines in a biochemical context mimicking tumour microenvironment conditions

Mahaweni, N. M., Bos, G. M. J., Mitsiades, C. S., Tilanus, M. G. J. & Wieten, L., 1 Jun 2018, In : Cancer Immunology Immunotherapy. 67, 6, p. 861-872 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Influence of Vitamin C on Lymphocytes: An Overview

van Gorkom, G. N. Y., Wolterink, R. G. J. K., Van Elssen, C. H. M. J., Wieten, L., Germeraad, W. T. V. & Bos, G. M. J., 10 Mar 2018, In : Antioxidants. 7, 3, 14 p., 41.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Open Access

Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-γ

Oth, T., Habets, T. H. P. M., Germeraad, W. T. V., Zonneveld, M. I., Bos, G. M. J. & Vanderlocht, J., 13 Feb 2018, In : BMC IMMUNOLOGY. 19, 13 p., 8.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Thalidomide before and after autologous stem cell transplantation in recently diagnosed multiple myeloma (HOVON-50): long-term results from the phase 3, randomised controlled trial

van de Donk, N. W. C. J., van der Holt, B., Minnema, M. C., Vellenga, E., Croockewit, S., Kersten, M. J., von dem Borne, P. A., Ypma, P., Schaafsma, R., de Weerdt, O., Klein, S. K., Delforge, M., Levin, M-D., Bos, G. M., Jie, K-S. G., Sinnige, H., Coenen, J. L. L. M., de Waal, E. G., Zweegman, S., Sonneveld, P. & 1 others, Lokhorst, H. M., 1 Oct 2018, In : The Lancet Haematology . 5, 10, p. E479-E492 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

The development of D antibodies after D-mismatched kidney transplantation in a setting of reduced immunosuppression

Habets, T. H. P. M., Vanderlocht, J., Straat, R. J. M. H. E., van Smaalen, T. C., Bos, G. M. J., Beckers, E. A., Christiaans, M. H. L. & Henskens, Y. M. C., 1 Jan 2018, In : Transfusion. 58, 1, p. 100-104 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The prevalence of antibodies against the HLA-DRB3 protein in kidney transplantation and the correlation with HLA expression

Habets, T. H. P. M., Hepkema, B. G., Kouprie, N., Schnijderberg, M. C. A., van Smaalen, T. C., Bungener, L. B., Christiaans, M. H. L., Bos, G. M. J. & Vanderlocht, J., 7 Sep 2018, In : PLOS ONE. 13, 9, 19 p., e0203381.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Tuning Natural Killer Cell Anti-multiple Myeloma Reactivity by Targeting Inhibitory Signaling via KIR and NKG2A

Mahaweni, N. M., Ehlers, F. A. I., Bos, G. M. J. & Wieten, L., 4 Dec 2018, In : Frontiers in Immunology. 9, 8 p., 2848.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2017

Bone marrow produces sufficient alloreactive natural killer (NK) cells in vivo to cure mice from subcutaneously and intravascularly injected 4T1 breast cancer

van Gelder, M., Vanclee, A., van Elssen, C. H. M. J., Hupperets, P., Wieten, L. & Bos, G. M., Feb 2017, In : Breast Cancer Research and Treatment. 161, 3, p. 421-433 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Permitting patients to pay for participation in clinical trials: the advent of the P4 trial

Shaw, D., de Wert, G., Dondorp, W., Townend, D., Bos, G. & van Gelder, M., Jun 2017, In : Medicine Health Care and Philosophy. 20, 2, p. 219-227 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Successful Transfer of Umbilical Cord Blood CD34+ Hematopoietic Stem and Progenitor-derived NK Cells in Older Acute Myeloid Leukemia Patients

Dolstra, H., Roeven, M. W. H., Spanholtz, J., Hangalapura, B. N., Tordoir, M., Maas, F., Leenders, M., Bohme, F., Kok, N., Trilsbeek, C., Paardekooper, J., van der Waart, A. B., Westerweel, P. E., Snijders, T. J. F., Cornelissen, J., Bos, G., Pruijt, H. F. M., de Graaf, A. O., van der Reijden, B. A., Jansen, J. H. & 6 others, van der Meer, A., Huls, G., Cany, J., Preijers, F., Blijlevens, N. M. A. & Schaap, N. M., 1 Aug 2017, In : Clinical Cancer Research. 23, 15, p. 4107-4118 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

‘Revival’ van de haplo-identieke stamceltransplantatie

van Gorkom, G., van Gelder, M., Wieten, L., von dem Borne, P. A., Schouten, H., Bos, G. & van Elssen, J., 2017, In : Nederlands Tijdschrift voor Hematologie. 14, p. 359-366 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016
2 Citations (Scopus)

Ascorbic acid serum levels are reduced in patients with hematological malignancies

Huijskens, M., Wodzig, W., Walczak, M., Germeraad, W. & Bos, G., 2016, In : Results in Immunology. 6, p. 8-10

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response

Habets, T. H. P. M., Oth, T., Houben, A., Huijskens, M. J. A. J., Senden-Gijsbers, B. L. M. G., Schnijderberg, M. C. A., Brans, B., Dubois, L. J., Lambin, P., De Saint-Hubert, M., Germeraad, W. T. V., Tilanus, M. G. J., Mottaghy, F. M., Bos, G. & Vanderlocht, J., 18 Jul 2016, In : PLOS ONE. 11, 7, e0159515.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Melphalan, prednisone, and lenalidomide versus melphalan, prednisone, and thalidomide in untreated multiple myeloma

Zweegman, S., van der Holt, B., Mellqvist, U-H., Salomo, M., Bos, G. M. J., Levin, M-D., Visser-Wisselaar, H., Hansson, M., van der Velden, A. W. G., Deenik, W., Gruber, A., Coenen, J. L. L. M., Plesner, T., Klein, S. K., Tanis, B. C., Szatkowski, D. L., Brouwer, R. E., Westerman, M., Leys, M. R. B. L., Sinnige, H. A. M. & 8 others, Haukas, E., van der Hem, K. G., Durian, M. F., Mattijssen, E. V. J. M., van de Donk, N. W. C. J., Stevens-Kroef, M. J. P. L., Sonneveld, P. & Waage, A., 3 Mar 2016, In : Blood. 127, 9, p. 1109-1116

Research output: Contribution to journalArticleAcademicpeer-review

Pancreatic atrophy after allogeneic peripheral blood stem cell transplantation

Moenen, F. C. J. I., Bakers, F. C. H. & Bos, G., Jan 2016, In : British Journal of Haematology. 172, 2, p. 155-155

Research output: Contribution to journalEditorialAcademicpeer-review

1 Citation (Scopus)

Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma

Nijhof, I. S., Franssen, L. E., Levin, M-D., Bos, G. M. J., Broijl, A., Klein, S. K., Koene, H. R., Bloem, A. C., Beeker, A., Faber, L. M., van der Spek, E., Ypma, P. F., Raymakers, R. A. P., van Spronsen, D. J., Westerweel, P. E., Oostvogels, R., van Velzen, J., van Kessel, B., Mutis, T., Sonneveld, P. & 3 others, Zweegman, S., Lokhorst, H. M. & van de Donk, N. W. C. J., 10 Nov 2016, In : Blood. 128, 19, p. 2297-2306

Research output: Contribution to journalArticleAcademicpeer-review

Phase I/II trial of weekly bortezomib with lenalidomide and dexamethasone in first relapse or primary refractory myeloma

Broijl, A., Kersten, M-J., Alemayehu, W. G., Levin, M-D., de Weerdt, O., Vellenga, E., Meijer, E., Wittebol, S., Tanis, B. C., Cornelisse, P. B., Stevens-Kroef, M., Bos, G. M. J., Wijermans, P. W., Lokhorst, H. & Sonneveld, P., Apr 2016, In : Haematologica-the Hematology Journal. 101, 4, e149.

Research output: Contribution to journalArticleAcademicpeer-review

2015
6 Citations (Scopus)

Heat-Transfer-Method-Based Cell Culture Quality Assay through Cell Detection by Surface Imprinted Polymers

Eersels, K., van Grinsven, B., Khorshid, M., Somers, V., Puttmann, C., Stein, C., Barth, S., Dilien, H., Bos, G. M. J., Germeraad, W. T. V., Cleij, T. J., Thoelen, R., De Ceuninck, W. & Wagner, P., 17 Feb 2015, In : Langmuir. 31, 6, p. 2043-2050

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Improving the sensitivity of the heat-transfer method (HTM) for cancer cell detection with optimized sensor chips

Eersels, K., van Grinsven, B., Vandenryt, T., Jimenez-Monroy, K. L., Peeters, M., Somers, V., Puettmann, C., Stein, C., Barth, S., Bos, G. M. J., Germeraad, W. T. V., Dilien, H., Cleij, T. J., Thoelen, R., De Ceuninck, W. & Wagner, P., Jun 2015, In : Physica Status Solidi A-applications and Materials Science. 212, 6, p. 1320-1326

Research output: Contribution to journalArticleAcademicpeer-review

Laat student echt meedoen in behandelteam, Maastrichts curriculum maakt stagiairs al vroeg verantwoordelijk

Rennenberg, R., Govaerts, M., Rethans, J-J. & Bos, G., 2015, In : Medisch Contact. 15, p. 726-728

Research output: Contribution to journalArticleAcademicpeer-review

2014
12 Citations (Scopus)

Clinical and immunological significance of HLA-E in stem cell transplantation and cancer

Wieten, L., Mahaweni, N. M., Voorter, C. E. M., Bos, G. M. J. & Tilanus, M. G. J., Dec 2014, In : Tissue Antigens. 84, 6, p. 523-535

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Heat-Transfer Resistance Measurement Method (HTM)-Based Cell Detection at Trace Levels Using a Progressive Enrichment Approach with Highly Selective Cell-Binding Surface Imprints

Bers, K., Eersels, K., van Grinsven, B., Daemen, M., Bogie, J. F. J., Hendriks, J. J. A., Bouwmans, E. E., Puettmann, C., Stein, C., Barth, S., Bos, G. M. J., Germeraad, W. T. V., De Ceuninck, W. & Wagner, P., 1 Apr 2014, In : Langmuir. 30, 12, p. 3631-3639

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Understanding the effects of time on collaborative learning processes in problem based learning: a mixed methods study

Hommes, J., van den Bossche, P., Grave, W., Bos, G., Schuwirth, L. & Scherpbier, A., 1 Jan 2014, In : Advances in Health Sciences Education. 19, 4, p. 541-563

Research output: Contribution to journalArticleAcademicpeer-review

2012
179 Downloads (Pure)

Nobelprijs voor Onderwijs

Bos, G. M. J., 7 Jun 2012, Maastricht: Maastricht University. 18 p.

Research output: Book/ReportInaugural speechPopular

Open Access
File
39 Citations (Scopus)

Visualising the invisible: a network approach to reveal the informal social side of student learning

Hommes, J., Rienties, B., de Grave, W., Bos, G., Schuwirth, L. & Scherpbier, A., Dec 2012, In : Advances in Health Sciences Education. 17, 5, p. 743-757

Research output: Contribution to journalArticleAcademicpeer-review

2011
4 Citations (Scopus)

Flow cytometry-based assay to evaluate human serum MUC1-Tn antibodies

Van Elssen, C., Clausen, H., Germeraad, W. T. V., Bennet, E. P., Menheere, P. P. C. A., Bos, G. M. J. & Vanderlocht, J., 28 Feb 2011, In : Journal of Immunological Methods. 365, 1-2, p. 87-94 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inflammation restraining effects of prostaglandin E2 on natural killer-dendritic cell (NK-DC) interaction are imprinted during DC maturation

Van Elssen, C. H. M. J., Vanderlocht, J., Oth, T., Senden-Gijsbers, B. L. M. G., Germeraad, W. T. V. & Bos, G. M. J., 1 Sep 2011, In : Blood. 118, 9, p. 2473-2482

Research output: Contribution to journalArticleAcademicpeer-review

2010

A randomized phase 3 study on the effect of thalidomide combined with adriamycin, dexamethasone, and high-dose melphalan, followed by thalidomide maintenance in patients with multiple myeloma

Lokhorst, H. M., van der Holt, B., Zweegman, S., Vellenga, E., Croockewit, S., van Oers, M. H., Borne, P. V. D., Wijermans, P., Schaafsma, M. R., de Weerdt, O., Wittebol, S., Delforge, M., Berenschot, H., Bos, G. M., Jie, K-S. G., Sinnige, H., van Marwijk-Kooy, M., Joosten, P., Minnema, M. C., van Ammerlaan, R. & 1 others, Sonneveld, P., 11 Feb 2010, In : Blood. 115, 6, p. 1113-1120

Research output: Contribution to journalArticleAcademicpeer-review

A translocation in acute lymphoblastic leukemia that cytogenetically mimics the recurrent MLL-AFF1 translocation and fuses SEPT11 to MLL

Stevens, S. J. C., Meers, L. E. C., Albrechts, J. C. M., Mebis-Verhees, K., Bos, G. M. J., Engelen, J. J. M. & Janssen, J. W. H., Aug 2010, In : Cancer Genetics and Cytogenetics. 201, 1, p. 48-51

Research output: Contribution to journalArticleAcademicpeer-review

Expression of aberrantly glycosylated Mucin-1 in ovarian cancer

Van Elssen, C. H. M. J., Frings, P. W. H., Bot, F. J., Van de Vijver, K. K., Huls, M. B., Meek, B., Hupperets, P., Germeraad, W. T. V. & Bos, G. M. J., Oct 2010, In : Histopathology. 57, 4, p. 597-606

Research output: Contribution to journalArticleAcademicpeer-review

HLA-matched allo-SCT after reduced intensity conditioning with fludarabine/CY in patients with metastatic breast cancer

Fleskens, S. A. J. H. M., Lalisang, R. I., Bos, G. M. J., van Gelder, M., Jansen, R. L. H. & Schouten, H. C., Mar 2010, In : Bone Marrow Transplantation. 45, 3, p. 464-467

Research output: Contribution to journalArticleAcademicpeer-review

In vitro-differentiated T/natural killer-cell progenitors derived from human CD34(+) cells mature in the thymus

Meek, B., Cloosen, S., Borsotti, C., Van Elssen, C. H. M. J., Vanderlocht, J., Schnijderberg, M. C. A., van der Poel, M. W. M., Leewis, B., Hesselink, R., Manz, M. G., Katsura, Y., Kawamoto, H., Germeraad, W. T. V. & Bos, G. M. J., 14 Jan 2010, In : Blood. 115, 2, p. 261-264

Research output: Contribution to journalArticleAcademicpeer-review

Klebsiella pneumoniae-triggered DC recruit human NK cells in a CCR5-dependent manner leading to increased CCL19-responsiveness and activation of NK cells

Van Elssen, C. H. M. J., Vanderlocht, J., Frings, P. W. H., Senden-Gijsbers, B. L. M. G., Schnijderberg, M. C. A., van Gelder, M., Meek, B., Libon, C., Ferlazzo, G., Germeraad, W. T. V. & Bos, G. M. J., Nov 2010, In : European Journal of Immunology. 40, 11, p. 3138-3149

Research output: Contribution to journalArticleAcademicpeer-review

Minocycline Inhibits Apoptotic Cell Death in a Murine Model of Partial Flap Loss

Dumont, E. A. W. J., Lutgens, S. P. M., Reutelingsperger, C. P. M., Bos, G. M. J. & Hofstra, L., Oct 2010, In : Journal of Reconstructive Microsurgery. 26, 8, p. 523-528

Research output: Contribution to journalArticleAcademicpeer-review

2007
11 Citations (Scopus)

Dietary polyunsaturated fat intake is associated with low-density lipoprotein size, but not with susceptibility to oxidation in subjects with impaired glucose metabolism and type II diabetes: the Hoorn study

Bos, G., Poortvliet, M. C., Scheffer, P. G., Dekker, J. M., Ocke, M. C., Nijpels, G., Stehouwer, C. D., Bouter, L. M., Teerlink, T. & Heine, R. J., 1 Jan 2007, In : European Journal of Clinical Nutrition. 61, 2, p. 205-211

Research output: Contribution to journalArticleAcademicpeer-review

2005

Interactions of dietary fat intake and the hepatic lipase -480C-->T polymorphism in determining hepatic lipase activity: the Hoorn Study

Bos, G. M. J., Dekker, J. M., Feskens, E., Ocke, M. C., Nijpels, G., Stehouwer, C. D., Bouter, L. M., Heine, R. J. & Jansen, H., 1 Jan 2005, In : American Journal of Clinical Nutrition. 81, 4, p. 911-915

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)

Keratinocyte growth factor ameliorates acute graft-versus-host disease in a novel nonmyeloablative haploidentical transplantation model

Vanclee, A. J. G., Lutgens, L. C. H. W., Oving, E. B., Deutz, N. E. P., Gijbels, M. J. J., Schouten, H. C. & Bos, G. M. J., 1 Jan 2005, In : Bone Marrow Transplantation. 36, 10, p. 907-915

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Opposite contributions of trunk and leg fat mass with plasma lipase activities: the Hoorn study

Bos, G. M. J., Snijder, M. B., Nijpels, G., Dekker, J. M., Stehouwer, C. D. A., Bouter, L. M., Heine, R. J. & Janssen, H. A. M., 1 Jan 2005, In : Obesity Research. 13, 10, p. 1817-1823

Research output: Contribution to journalArticleAcademicpeer-review

2004
12 Citations (Scopus)

LDL oxidative modifications in well- or moderately controlled type 2 diabetes

Scheffer, P. G., Henry, R. M. A., Wever, E. J. M., van Rooij, G. J., Bos, G. M. J., Heine, R. J., Dekker, J. M., Diamant, M., Stehouwer, C. D. A., Nijpels, G., Blankenstein, M. A. & Teerlink, T., 1 Jan 2004, In : Diabetes-metabolism Research and Reviews. 20, 4, p. 298-304

Research output: Contribution to journalArticleAcademicpeer-review