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Research Output 2002 2019

2019

CASCADE OF CARE IN CHRONIC HEPATITIS C PATIENTS IN THE NETHERLANDS: HAS ACCESS TO CARE CHANGED IN THE PERIOD OF DIRECT-ACTING ANTIVIRALS?

van Oorschot, E., Koc, O., Posthouwer, D., Lashof, A. O., Van Loo, I., Ackens, R. & Koek, G. H., Oct 2019, In : Hepatology. 70, p. 341A-341A 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Crashing NASH in Patients Listed for Bariatric Surgery

De Munck, T. J. I., Verhaegh, P. L. M., Verbeek, J., Verheij, J., Greve, J. W., Jonkers, D. M. A. E., Masclee, A. A. M. & Koek, G. H., Mar 2019, In : Obesity Surgery. 29, 3, p. 1012-1014 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients

Yagmur, E., Otto, S., Koek, G. H., Weiskirchen, R., Trautwein, C., Koch, A. & Tacke, F., Jun 2019, In : Diagnostics. 9, 2, 13 p., 63.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of Plasmapheresis on Cholestatic Pruritus and Autotaxin Activity During Pregnancy

Heerkens, M., Dedden, S., Scheepers, H., Van Paassen, P., Masclee, A., de Die-Smulders, C., Olde Damink, S. W. M., Schaap, F. G., Jansen, P., Koek, G., Beuers, U. & Verbeek, J., Jun 2019, In : Hepatology. 69, 6, p. 2707-2710 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Elevated CTRP1 Plasma Concentration Is Associated with Sepsis and Pre-Existing Type 2 Diabetes Mellitus in Critically Ill Patients

Yagmur, E., Buergerhausen, D., Koek, G. H., Weiskirchen, R., Trautwein, C., Koch, A. & Tacke, F., May 2019, In : Journal of Clinical Medicine. 8, 5, 11 p., 661.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hyperferritinemia in Nonalcoholic Fatty Liver Disease: Iron Accumulation or Inflammation?

Moris, W., Verhaegh, P., Jonkers, D., van Deursen, C. & Koek, G., Nov 2019, In : Seminars in Liver Disease. 39, 4, p. 476-482 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content

Simons, N., Debray, F-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D. & Brouwers, M. C. G. J., Nov 2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 11, p. 5053-5061 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury

Zoubek, M. E., Woitok, M. M., Sydor, S., Nelson, L. J., Bechmann, L. P., Lucena, M. I., Andrade, R. J., Bast, A., Koek, G. H., Trautwein, C. & Cubero, F. J., Jan 2019, In : Journal of Pathology. 247, 1, p. 110-122 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Review and gap analysis: molecular pathways leading to fetal alcohol spectrum disorders

Ehrhart, F., Roozen, S., Verbeek, J., Koek, G., Kok, G., van Kranen, H., Evelo, C. T. & Curfs, L. M. G., 2019, In : Molecular Psychiatry. 24, 1, p. 10-17 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The influence of ethnicity on disease outcome in patients with chronic hepatitis B infection

Koc, O. M., Robaeys, G., Yildirim, B., Posthouwer, D., Hens, N. & Koek, G. H., Apr 2019, In : Journal of Medical Virology. 91, 4, p. 623-629 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Clinical relevance of copeptin plasma levels as a biomarker of disease severity and mortality in critically ill patients

Koch, A., Yagmur, E., Hoss, A., Buendgens, L., Herbers, U., Weiskirchen, R., Koek, G. H., Trautwein, C. & Tacke, F., Nov 2018, In : Journal of Clinical Laboratory Analysis. 32, 9, 6 p., 22614.

Research output: Contribution to journalArticleAcademicpeer-review

High Circulating Caspase-Cleaved Keratin 18 Fragments (M30) Indicate Short-Term Mortality in Critically Ill Patients

Koch, A., Yagmur, E., Linka, J., Schumacher, F., Bruensing, J., Buendgens, L., Herbers, U., Koek, G. H., Weiskirchen, R., Trautwein, C. & Tacke, F., 1 Jan 2018, In : Disease Markers. 2018, 8 p., 8583121.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

High mobility group box 1 as a biomarker in critically ill patients

Yagmur, E., Buendgens, L., Herbers, U., Beeretz, A., Weiskirchen, R., Koek, G. H., Trautwein, C., Tacke, F. & Koch, A., 1 Oct 2018, In : Journal of Clinical Laboratory Analysis. 32, 8, 7 p., e22584.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Horizontal hepatitis B virus transmission through non-sexual close contact in Turkish chronic hepatitis B patients living outside of Turkey

Koc, O. M., Robaeys, G., Yildirim, B., Posthouwer, D., Hens, N. & Koek, G. H., 2018, In : Acta gastro-Enterologica belgica. 81, 4, p. 503-508 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Systematic literature review on which maternal alcohol behaviours are related to fetal alcohol spectrum disorders (FASD)

Roozen, S., Peters, G-J. Y., Kok, G., Townend, D., Nijhuis, J., Koek, G. & Curfs, L., 19 Dec 2018, In : BMJ Open. 8, 12, p. e022578 12 p., 022578.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The Clinical Relevance of Differentiating Nonalcoholic Steatohepatitis From Simple Steatosis Reply

Verhaegh, P., Jonkers, D. & Koek, G. H., Apr 2018, In : Clinical gastroenterology and hepatology. 16, 4, p. 596-597 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Visfatin Serum Levels Predict Mortality in Critically Ill Patients

Koch, A., Weiskirchen, R., Krusch, A., Bruensing, J., Buendgens, L., Herbers, U., Yagmur, E., Koek, G. H., Trautwein, C. & Tacke, F., 1 Jan 2018, In : Disease Markers. 2018, p. 1-8 8 p., 7315356.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis

Kremers, R. M. W., Kleinegris, M-C., Ninivaggi, M., de Laat, B., ten Cate, H., Koek, G. H., Wagenvoord, R. J. & Hemker, H. C., 4 May 2017, In : PLOS ONE. 12, 5, 17 p., 0177020.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hypothermic oxygenated machine perfusion (HOPE) for orthotopic liver transplantation of human liver allografts from extended criteria donors (ECD) in donation after brain death (DBD): a prospective multicentre randomised controlled trial (HOPE ECD-DBD)

Czigany, Z., Schoening, W., Ulmer, T. F., Bednarsch, J., Amygdalos, I., Cramer, T., Rogiers, X., Popescu, I., Botea, F., Fronek, J., Kroy, D., Koch, A., Tacke, F., Trautwein, C., Tolba, R. H., Hein, M., Koek, G. H., Dejong, C. H. C., Neumann, U. P. & Lurje, G., Oct 2017, In : BMJ Open. 7, 10, 9 p., 017558.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Identifying psycho-social determinants and environmental conditions related to alcohol consumption during pregnancy

Roozen, S., Peters, G-J., Kok, G., Townend, D., Koek, G., Nijhuis, J. & Curfs, L., 2017, In : The European Health Psychologist. 19 (Supp.), p. 1122

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease

Simons, N., Isaacs, A., Koek, G. H., Kuc, S., Schaper, N. C. & Brouwers, M. C. G. J., Mar 2017, In : Gastroenterology. 152, 4, p. 912-913 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Proton Pump Inhibitors Decrease Phlebotomy Need in HFE Hemochromatosis: Double-Blind Randomized Placebo-Controlled Trial

Vanclooster, A., van Deursen, C., Jaspers, R., Cassiman, D. & Koek, G., Sep 2017, In : Gastroenterology. 153, 3, p. 678-680.e2 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Review of familial cerebral cavernous malformations and report of seven additional families

de Vos, I. J. H. M., Vreeburg, M., Koek, G. H. & van Steensel, M. A. M., Feb 2017, In : American Journal of Medical Genetics Part A. Part A 173A, 2, p. 338-351 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

State of the art and setting priorities for fetal alcohol spectrum disorder(s) prevention and management

Roozen, S., Peters, G-J., Kok, G., Townend, D., Koek, G., Nijhuis, J. & Curfs, L., 2017, In : The European Health Psychologist. 19 (Supp.), p. 598

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

The Increasing Burden of NAFLD Fibrosis in the General Population: Time to Bridge the Gap Between Hepatologists and Primary Care

van Asten, M., Verhaegh, P., Koek, G. & Verbeek, J., Mar 2017, In : Hepatology. 65, 3, p. 1078-1078 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

The Potential of Flavonoids in the Treatment of Non-alcoholic Fatty Liver Disease

van de Wier, B., Koek, G. H., Bast, A. & Haenen, G. R. M., 2017, In : Critical Reviews in Food Science and Nutrition. 57, 4, p. 834-855 22 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016
2 Citations (Scopus)

Erythrocytapheresis versus phlebotomy in the maintenance treatment of HFE hemochromatosis patients: results from a randomized crossover trial

Rombout-Sestrienkova, E., Winkens, B., Essers, B., Nieman, F., Noord, P. A., Janssen, M. C., van Deursen, C. T. B. M., Boonen, A., Reuser-Kaasenbrood, E. P., Heeremans, J., van Kraaij, M., Masclee, A. & Koek, G., 1 Jan 2016, In : Transfusion. 56, 1, p. 261-270 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Fetal alcohol spectrum disorders: A problem to solve

Roozen, S., Peters, G-J., Kok, G., Townend, D., Nijhuis, J., Koek, G. & Curfs, L., 22 Jul 2016, p. 729.

Research output: Contribution to conferenceAbstractAcademic

130 Downloads (Pure)

Fetal Alcohol Spectrum Disorders (FASD): an Approach to Effective Prevention

Roozen, S., Black, D., Peters, G-J., Kok, G., Townend, D., Nijhuis, J., Koek, G. & Curfs, L., Oct 2016, In : Current Developmental Disorders Reports. 3, 4, p. 229-234

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
1 Citation (Scopus)

How the concept of biochemical response influenced the management of primary biliary cholangitis over time

Lammers, W. J., Leeman, M., Ponsioen, C. I. J., Boonstra, K., van Erpecum, K. J., Wolfhagen, F. H. J., Kuyvenhoven, J. P., Vrolijk, J. M., Drenth, J. P. H., Witteman, E. M., van Nieuwkerk, C. M. J., van der Spek, B. W., Witteman, B. J. M., Erkelens, G. W., Verhagen, M. A. M. T., van Tuyl, S. A. C., Poen, A. C., Brouwer, J. T., ter Borg, F., Koek, G. H. & 3 others, van Ditzhuijsen, T. J. M., Hansen, B. E. & van Buuren, H. R., Jul 2016, In : Netherlands Journal of Medicine. 74, 6, p. 240-246

Research output: Contribution to journalArticleAcademicpeer-review

How we manage patients with hereditary haemochromatosis

Rombout-Sestrienkova, E., van Kraaij, M. G. J. & Koek, G. H., Dec 2016, In : British Journal of Haematology. 175, 5, p. 759-770

Research output: Contribution to journalArticleAcademicpeer-review

Is intestinal oxidative stress involved in patients with compensated liver cirrhosis?

Pijls, K., Jonkers, D., Elizalde Vilalta, M., Drittij - Reijnders, M. J., Haenen, G., Bast, A., Masclee, A. & Koek, G., 2016, In : Annals of Hepatology. 15, 3, p. 402-409 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Low levels of IgM antibodies recognizing oxidation-specific epitopes are associated with human non-alcoholic fatty liver disease

Hendrikx, T., Watzenboeck, M. L., Walenbergh, S. M. A., Amir, S., Gruber, S., Kozma, M. O., Grabsch, H. I., Koek, G. H., Pierik, M. J., Staufer, K., Trauner, M., Kalhan, S. C., Jonkers, D., Hofker, M. H., Binder, C. J. & Shiri-Sverdlov, R., 22 Jul 2016, In : BMC Medicine. 14, 13 p., 107.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Persisterende verhoging van transaminasewaarden: Een patiënt met een late variant van de ziekte van Pomp

Sanders, K. J. C., Hermans, M. C. E. & Koek, G., 2016, In : Nederlands Tijdschrift voor Geneeskunde. 160, A9904.

Research output: Contribution to journalEditorialAcademicpeer-review

1 Citation (Scopus)

Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

Walenbergh, S. M. A., Houben, T., Rensen, S. S., Bieghs, V., Hendrikx, T., van Gorp, P. J., Oligschläger, Y., Jeurissen, M. L. J., Gijbels, M. J. J., Buurman, W. A., Vreugdenhil, A. C. E., Greve, J. W. M., Plat, J., Hofker, M. H., Kalhan, S., Pihlajamaki, J., Lindsey, P., Koek, G. H. & Shiri-Sverdlov, R., 6 Dec 2016, In : Scientific Reports. 6, 38278.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
7 Citations (Scopus)

Proton Pump Inhibitors Reduce the Frequency of Phlebotomy in Patients With Hereditary Hemochromatosis

van Aerts, R. M. M., van Deursen, C. & Koek, G. H., Jan 2016, In : Clinical gastroenterology and hepatology. 14, 1, p. 147-152

Research output: Contribution to journalArticleAcademicpeer-review

Response to can modifier gene mutations improve the predictive value of the modified Iron Avidity Index in Type 1 Hereditary Haemochromatosis?

Verhaegh, P. L. M., Moris, W., Koek, G. H. & van Deursen, C. T. B. M., Nov 2016, In : Liver International. 36, 11, p. 1714-1714

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Seroprevalence of Hepatitis E Virus in Autoimmune Hepatitis Patients in the Netherlands

Koek, G., Mar 2016, In : Journal of Gastrointestinal and Liver Diseases. 25, 1, p. 9-13

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Sinusoidal obstruction syndrome (SOS): A light and electron microscopy study in human liver

Vreuls, C., Driessen, A., Olde Damink, S., Koek, G., Duimel, H., van den Broek, M. A., Dejong, C. H. C., Braet, F. & Wisse, E., May 2016, In : Micron. 84, p. 17-22 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

The modified iron avidity index: a promising phenotypic predictor in HFE-related haemochromatosis

Verhaegh, P. L. M., Moris, W., Koek, G. H. & van Deursen, C. T. B. M., Oct 2016, In : Liver International. 36, 10, p. 1535-1539

Research output: Contribution to journalArticleAcademicpeer-review

Understanding Foetal Alcohol Spectrum Disorders (FASD) and maternal alcohol consumption during pregnancy

Roozen, S., Peters, G-J., Kok, G., Townend, D., Koek, G., Nijhuis, J. & Curfs, L., 2016, p. 728.

Research output: Contribution to conferenceAbstractAcademic

Open Access
2002
5 Citations (Scopus)

Hyperemesis gravidarum and severe liver enzyme elevation

Conchillo, J. M. & Koek, G. H., 1 Jan 2002, In : Journal of Hepatology. 37, 1, p. 162-3

Research output: Contribution to journalArticleAcademicpeer-review