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Research Output

2019

Airflow Obstruction and Cardio-metabolic Comorbidities

Triest, F. J. J., Studnicka, M., Franssen, F. M. E., Vollmer, W. M., Lamprecht, B., Wouters, E. F. M., Burney, P. G. J. & Vanfleteren, L. E. G. W., 4 Mar 2019, In : Copd-Journal of Chronic Obstructive Pulmonary Disease. 16, 2, p. 109-117 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD)

Oshagbemi, O. A., Franssen, F. M. E., van Kraaij, S., Braeken, D. C. W., Wouters, E. F. M., Maitland-van der Zee, A. H., Driessen, J. H. M. & de Vries, F., 2019, In : COPD. 16, 2, p. 152-159 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chronic Obstructive Pulmonary Disease: Shifting the Paradigm to the Vasculature

Wouters, E. F. M. & Franssen, F. M., 1 Feb 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 3, p. 258-259 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Clinical impact of body composition phenotypes in patients with COPD: a retrospective analysis

Machado, F. V. C., Schneider, L. P., Fonseca, J., Belo, L. F., Bonomo, C., Morita, A. A., Furlanetto, K. C., Felcar, J. M., Rodrigues, A., Franssen, F. M. E., Spruit, M. A., Pitta, F. & Hernandes, N. A., Nov 2019, In : European Journal of Clinical Nutrition. 73, 11, p. 1512-1519 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Comprehensive Lung Function Assessment Does not Allow to Infer Response to Pulmonary Rehabilitation in Patients with COPD

Augustin, I. M. L., Wouters, E. E. M., Houben-Wilke, S., Gaffron, S., Janssen, D. J. A., Franssen, F. M. E. & Spruit, M. A., Jan 2019, In : Journal of Clinical Medicine. 8, 1, p. 1-11 11 p., 27.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diagnostic and Therapeutic Gaps in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease

Canepa, M., Franssen, F. M. E., Olschewski, H., Lainscak, M., Boehm, M., Tavazzi, L. & Rosenkranz, S., Oct 2019, In : JACC-Heart Failure. 7, 10, p. 823-833 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging

Triest, F. J. J., Franssen, F. M. E., Reynaert, N., Gaffron, S., Spruit, M. A., Janssen, D. J. A., Rutten, E. P. A., Wouters, E. F. M. & Vanfleteren, L. E. G. W., Apr 2019, In : Journal of Clinical Medicine. 8, 4, p. 1-18 18 p., 511.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Emphysema: looking beyond alpha-1 antitrypsin deficiency

Janssen, R., Piscaer, I., Franssen, F. M. E. & Wouters, E. F. M., 3 Apr 2019, In : Expert Review of Respiratory Medicine. 13, 4, p. 381-397 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

ERS statement on standardisation of cardiopulmonary exercise testing in chronic lung diseases

Radtke, T., Crook, S., Kaltsakas, G., Louvaris, Z., Berton, D., Urquhart, D. S., Kampouras, A., Rabinovich, R. A., Verges, S., Kontopidis, D., Boyd, J., Tonia, T., Langer, D., De Brandt, J., Goertz, Y. M. J., Burtin, C., Spruit, M. A., Braeken, D. C. W., Dacha, S., Franssen, F. M. E. & 8 others, Laveneziana, P., Eber, E., Troosters, T., Neder, J. A., Puhan, M. A., Casaburi, R., Vogiatzis, I. & Hebestreit, H., 31 Dec 2019, In : European Respiratory Review. 28, 154, 25 p., 1901441.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

External Validation Of The Updated ADO Score In COPD Patients From The Birmingham COPD Cohort

Keene, S. J., Jordan, R. E., Franssen, F. M. E., de Vries, F., Martin, J., Sitch, A., Turner, A. M., Dickens, A. P., Fitzmaurice, D. & Adab, P., 2019, In : International journal of chronic obstructive pulmonary disease. 14, p. 2395-2407 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation

Goertz, Y. M. J., Spruit, M. A., Van't Hul, A. J., Peters, J. B., Van Herck, M., Nakken, N., Djamin, R. S., Burtin, C., Thong, M. S. Y., Coors, A., Meertens-Kerris, Y., Wouters, E. F. M., Prins, J. B., Franssen, F. M. E., Muris, J. W. M., Vanfleteren, L. E. G. W., Sprangers, M. A. G., Janssen, D. J. A. & Vercoulen, J. H., Sep 2019, In : Therapeutic Advances in Respiratory Disease. 13, 13 p., 1753466619878128.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Impact of pulmonary rehabilitation on activities of daily living in patients with chronic obstructive pulmonary disease

Vaes, A. W., Delbressine, J. M. L., Mesquita, R., Goertz, Y. M. J., Janssen, D. J. A., Nakken, N., Franssen, F. M. E., Vanfleteren, L. E. G. W., Wouters, E. F. M. & Spruit, M. A., Mar 2019, In : Journal of Applied Physiology. 126, 3, p. 607-615 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease

Piscaer, I., van den Ouweland, J. M. W., Vermeersch, K., Reynaert, N. L., Franssen, F. M. E., Keene, S., Wouters, E. F. M., Janssens, W., Vermeer, C. & Janssen, R., Aug 2019, In : Journal of Clinical Medicine. 8, 8, 14 p., 1116.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Optimizing health in chronic lung diseases: What did we learn from the experts in pulmonary rehabilitation?

Alison, J. A. & Franssen, F. M. E., Sep 2019, In : Respirology. 24, 9, p. 916-917 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Personalized medicine for patients with COPD: where are we?

Franssen, F. M. E., Alter, P., Bar, N., Benedikter, B. J., Iurato, S., Maier, D., Maxheim, M., Roessler, F. K., Spruit, M. A., Vogelmeier, C. F., Wouters, E. F. M., Schmeck, B. & SysMed-COPD Consortium, 2019, In : International journal of chronic obstructive pulmonary disease. 14, p. 1465-1484 20 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Pulmonary rehabilitation, physical activity, respiratory failure and palliative respiratory care

Spruit, M. A., Rochester, C. L., Pitta, F., Kenn, K., Schols, A. M. W. J., Hart, N., Wouters, E. F. M., Nava, S., Dreher, M., Janssen, D. J. A., Johnson, M. J., Curtis, R. J., Sastry, M. & Franssen, F. M. E., Jul 2019, In : Thorax. 74, 7, p. 693-699 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Rehabilitation in chronic respiratory diseases: Live your life to the max

Franssen, F. M. E. & Alison, J. A., Sep 2019, In : Respirology. 24, 9, p. 828-829 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Revealing Methodological Challenges in Chronic Obstructive Pulmonary Disease Studies Assessing Comorbidities: A Narrative Review

Houben-Wilke, S., Triest, F. J. J., Franssen, F. M. E., Janssen, D. J. A., Wouters, E. F. M. & Vanfleteren, L. E. G. W., Apr 2019, In : Chronic Obstructive Pulmonary Diseases : Journal of the COPD Foundation. 6, 2, p. 166-177 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Risk stratification for short-term mortality at hospital admission for acute exacerbations of COPD

Sprooten, R. T. M., Rohde, G. G. U., Lawyer, G., Leijte, W. T., Wouters, E. F. M. & Franssen, F. M. E., Aug 2019, In : Respirology. 24, 8, p. 765-776 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Standardisation of cardiopulmonary exercise testing in chronic lung diseases: summary of key findings from the ERS task force

Radtke, T., Vogiatzis, I., Urquhart, D. S., Laveneziana, P., Casaburi, R., Hebestreit, H., Radtke, T., Crook, S., Kaltsakas, G., Louvaris, Z., Berton, D. C., Urquhart, D. S., Kampouras, A., Rabinovich, R. A., Verges, S., Kontopidis, D., Boyd, J., Tonia, T., Langer, D., De Brandt, J. & 15 others, Goertz, Y. M. J., Burtin, C., Spruit, M. A., Braeken, D. C. W., Dacha, S., Franssen, F. M. E., Laveneziana, P., Eber, E., Troosters, T., Neder, J. A., Puhan, M. A., Casaburi, R., Vogiatzis, I., Hebestreit, H. & European Resp Soc Task, 1 Dec 2019, In : European Respiratory Journal. 54, 6, 5 p., 1901441.

Research output: Contribution to journalEditorialAcademicpeer-review

The superexacerbator phenotype in patients with COPD: a descriptive analysis

Vanfleteren, L. E. G. W., Boonen, L. M. C., Spruit, M. A., Janssen, D. J. A., Wouters, E. F. M. & Franssen, F. M. E., 1 Apr 2019, In : ERJ Open Research. 5, 2, 4 p., 00235-2018.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access
2018

An old debate still in the beta-phase?

Aizpurua, A. B., Franssen, F. M. E., van Empel, V. & Brunner-La Rocca, H-P., 1 Mar 2018, In : European journal of heart failure. 20, 3, p. 557-559 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality

Oshagbemi, O. A., Franssen, F. M. E., Braeken, D. C. W., Henskens, Y., Wouters, E. F. M., Maitland-van der Zee, A-H., Burden, A. M. & de Vries, F., Nov 2018, In : Pharmacoepidemiology and Drug Safety. 27, 11, p. 1191-1199 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Changes in lower limb muscle function and muscle mass following exercise-based interventions in patients with chronic obstructive pulmonary disease: A review of the English-language literature

De Brandt, J., Spruit, M. A., Hansen, D., Franssen, F. M. E., Derave, W., Sillen, M. J. H. & Burtin, C., May 2018, In : Chronic respiratory disease. 15, 2, p. 182-219 38 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Cognitive impairment and clinical characteristics in patients with chronic obstructive pulmonary disease

Cleutjens, F. A. H. M., Spruit, M. A., Ponds, R. W. H. M., Vanfleteren, L. E. G. W., Franssen, F. M. E., Gijsen, C., Dijkstra, J. B., Wouters, E. F. M. & Janssen, D. J. A., May 2018, In : Chronic respiratory disease. 15, 2, p. 91-102 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Contribution of individual COPD assessment test (CAT) items to CAT total score and effects of pulmonary rehabilitation on CAT scores

Houben-Wilke, S., Janssen, D. J. A., Franssen, F. M. E., Vanfleteren, L. E. G. W., Wouters, E. F. M. & Spruit, M. A., 30 Oct 2018, In : Health and Quality of Life Outcomes. 16, 8 p., 205.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

COPD patient education and support - Achieving patient-centredness

Stoilkova-Hartmann, A., Franssen, F. M. E., Augustin, I. M. L., Wouters, E. F. M. & Barnard, K. D., 1 Nov 2018, In : Patient Education and Counseling. 101, 11, p. 2031-2036 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

COPD stands for complex obstructive pulmonary disease

Houben-Wilke, S., Augustin, I. M., Vercoulen, J. H., van Ranst, D., de Vaate, E. B., Wempe, J. B., Spruit, M. A., Wouters, E. F. M. & Franssen, F. M. E., 30 Jun 2018, In : European Respiratory Review. 27, 148, p. 1-12 12 p., 180027.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Determinants of functional, peak and endurance exercise capacity in people with chronic obstructive pulmonary disease

McNamara, R. J., Houben-Wilke, S., Franssen, F. M. E., Smid, D. E., Vanfleteren, L. E. G. W., Groenen, M. T. J., Uszko-Lencer, N. H. M. K., Wouters, E. F. M., Alison, J. A. & Spruit, M. A., May 2018, In : Respiratory Medicine. 138, p. 81-87 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effectiveness of Pulmonary Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease With Different Degrees of Static Lung Hyperinflation

Vanfleteren, M. J., Koopman, M., Spruit, M. A., Pennings, H-J., Smeenk, F., Pieters, W., van den Bergh, J. J., Michels, A-J., Wouters, E. F., Groenen, M. T., Franssen, F. M. & Vanfleteren, L. E., Nov 2018, In : Archives of Physical Medicine and Rehabilitation. 99, 11, p. 2279-2286 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inhaled corticosteroids in COPD: friend or foe?

Agusti, A., Fabbri, L. M., Singh, D., Vestbo, J., Celli, B., Franssen, F. M. E., Rabe, K. F. & Papi, A., 1 Dec 2018, In : European Respiratory Journal. 52, 6, 14 p., 1801219.

Research output: Contribution to journalReview articleAcademicpeer-review

Looking into the eye of patients with chronic obstructive pulmonary disease: an opportunity for better microvascular profiling of these complex patients

Vaes, A. W., Spruit, M. A., Theunis, J., Goswami, N., Vanfleteren, L. E., Franssen, F. M. E., Wouters, E. F. M. & De Boever, P., Sep 2018, In : Acta Ophthalmologica. 96, 6, p. 539-549 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Personalised pulmonary rehabilitation in COPD

Wouters, E. F. M., Wouters, B. B. R. E. F., Augustin, I. M. L., Houben-Wilke, S., Vanfleteren, L. E. G. W. & Franssen, F. M. E., 31 Mar 2018, In : European Respiratory Review. 27, 147, 8 p., 170125.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Pulmonary rehabilitation for patients with COPD during and after an exacerbation-related hospitalisation: back to the future?

Spruit, M. A., Singh, S. J., Rochester, C. L., Greening, N. J., Franssen, F. M. E., Pitta, F., Troosters, T., Nolan, C., Vogiatzis, I., Clini, E. M., Man, W. D-C., Burtin, C., Goldstein, R. S., Vanfleteren, L. E. G. W., Kenn, K., Nici, L., Janssen, D. J. A., Casaburi, R., Shioya, T., Garvey, C. & 5 others, Carlin, B. W., ZuWallack, R. L., Steiner, M., Wouters, E. F. M. & Puhan, M. A., 1 Jan 2018, In : European Respiratory Journal. 51, 1, p. 1-4 4 p., 1701312.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

The physical, mental, and social impact of COPD in a population-based sample: results from the Longitudinal Aging Study Amsterdam

Franssen, F. M. E., Smid, D. E., Deeg, D. J. H., Huisman, M., Poppelaars, J., Wouters, E. F. M. & Spruit, M. A., 10 Aug 2018, In : npj Primary Care Respiratory Medicine. 28, 6 p., 30.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013

Oshagbemi, O. A., Keene, S. J., Driessen, J. H. M., Jordan, R., Wouters, E. F. M., de Boer, A., de Vries, F. & Franssen, F. M. E., Nov 2018, In : Respiratory Medicine. 144, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Use of high-dose intermittent systemic glucocorticoids and the risk of fracture in patients with chronic obstructive pulmonary disease

Oshagbemi, O. A., Burden, A. M., Shudofsky, K. N., Driessen, J. H. M., Vestergaard, P., Krings, A., Franssen, F. M. E., van den Bergh, J. & de Vries, F., May 2018, In : Bone. 110, p. 238-243 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Assessment of Burden of COPD (ABC) tool: perception versus evidence

Houben-Wilke, S., Franssen, F. M. E., Kok, I., Otten, H. J., Wempe, J. P. & Vercoulen, J. H., Mar 2017, In : European Respiratory Journal. 49, 3, 4 p., 1602382.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Bacterial aetiology and mortality in COPD patients with CAP: results from the German Competence Network, CAPNETZ

Braeken, D. C. W., Franssen, F. M. E., von Baum, H., Schuette, H., Pletz, M. W., Rupp, J., Stassen, F., Mooij, M. J., Rohde, G. G. U. & CAPNETZ Study Grp, Feb 2017, In : International Journal of Tuberculosis and Lung Disease. 21, 2, p. 236-243 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Breathe journal club: virtually meet the experts

Franssen, F. M. E., 1 Mar 2017, In : Breathe. 13, 1, p. 9-10 2 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Clinical highlights from the 2016 European Respiratory Society International Congress

Kahn, N., Fregonese, L., Barrecheguren, M., Franssen, F. M. E., Grgic, A., Gompelmann, D., Bibaki, E., Antoniou, K. M., Kocks, J. W. H., Pinnock, H. & Herth, F., Apr 2017, In : ERJ Open Research. 3, 2, 9 p., 00147-2016.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Domain-specific cognitive impairment in patients with COPD and control subjects

Cleutjens, F. A. H. M., Franssen, F. M. E., Spruit, M. A., Vanfleteren, O. E. G. W., Gijsen, C., Dijkstra, J. B., Ponds, R. W. H. M., Wouters, E. F. M. & Janssen, D. J. A., 2017, In : International journal of chronic obstructive pulmonary disease. 12, p. 1-11 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Echocardiographic abnormalities and their impact on health status in patients with COPD referred for pulmonary rehabilitation

Houben-Wilke, S., Spruit, M. A., Uszko-Lencer, N. H. M. K., Otkinska, G., Vanfleteren, L. E. G. W., Jones, P. W., Wouters, E. F. M. & Franssen, F. M. E., Jul 2017, In : Respirology. 22, 5, p. 928-934 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of an Outpatient Pulmonary Rehabilitation Program on Exercise Tolerance and Asthma Control in Obese Asthma Patients

Turk, Y., van Huisstede, A., Franssen, F. M. E., Hiemstra, P. S., Rudolphus, A., Taube, C. & Braunstahl, G-J., May 2017, In : Journal of Cardiopulmonary Rehabilitation and Prevention. 37, 3, p. 214-222 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Endothelial function in patients with chronic obstructive pulmonary disease: a systematic review of studies using flow mediated dilatation

Vaes, A. W., Spruit, M. A., Theunis, J., Goswami, N., Vanfleteren, L. E., Franssen, F. M. E., Wouters, E. F. M. & De Boever, P., 2017, In : Expert Review of Respiratory Medicine. 11, 12, p. 1021-1031 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

High intensity training in obesity: a Meta-analysis

Turk, Y., Theel, W., Kasteleyn, M. J., Franssen, F. M. E., Hiemstra, P. S., Rudolphus, A., Taube, C. & Braunstahl, G. J., Sep 2017, In : Obesity science & practice. 3, 3, p. 258-271 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

How Do Dual Long-Acting Bronchodilators Prevent Exacerbations of Chronic Obstructive Pulmonary Disease?

Beeh, K. M., Burgel, P-R., Franssen, F. M. E., Luis Lopez-Campos, J., Loukides, S., Hurst, J. R., Flezar, M., Ulrik, C. S., Di Marco, F., Stolz, D., Valipour, A., Casserly, B., Stallberg, B., Kostikas, K. & Wedzicha, J. A., 15 Jul 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 2, p. 139-149 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access