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Research Output

2018

Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease

Geijselaers, S. L. C., Aalten, P., Ramakers, I. H. G. B., De Deyn, P. P., Heijboer, A. C., Koek, H. L., OldeRikkert, M. G. M., Papma, J. M., Reesink, F. E., Smits, L. L., Stehouwer, C. D. A., Teunissen, C. E., Verhey, F. R. J., van der Flier, W. M., Biessels, G. J. & Inst Neurodegenerative Dis Study G, 1 Jan 2018, In : Journal of Alzheimer's Disease. 61, 1, p. 309-320 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Barriers and facilitators to the access to and use of formal dementia care: findings of a focus group study with people with dementia, informal carers and health and social care professionals in eight European countries

Stephan, A., Bieber, A., Hopper, L., Joyce, R., Irving, K., Zanetti, O., Portolani, E., Kerpershoek, L., Verhey, F., de Vugt, M., Wolfs, C., Eriksen, S., Rosvik, J., Marques, M. J., Goncalves-Pereira, M., Sjolund, B-M., Jelley, H., Woods, B., Meyer, G. & ActifCare Consortium, 4 Jun 2018, In : BMC Geriatrics. 18, 16 p., 131.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Baseline Vascular Cognitive Impairment Predicts the Course of Apathetic Symptoms After Stroke: The CASPER Study

Douven, E., Kohler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. R. J. & Aalten, P., 1 Mar 2018, In : American Journal of Geriatric Psychiatry. 26, 3, p. 291-300 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Behandeling van een stil delier: Wel of geen antipsychotica?

van Velthuijsen, E., Zwakhalen, S., Kempen, G. I. J. M. & Verhey, F., 2018, In : Nederlands Tijdschrift voor Geneeskunde. 162, D2660, p. 1-7 7 p., D2660.

Research output: Contribution to journalArticleAcademicpeer-review

Behavior and Evolution of Young ONset Dementia part 2 (BEYOND-II) study: an intervention study aimed at improvement in the management of neuropsychiatric symptoms in institutionalized people with young onset dementia

van Duinen-van den IJssel, J. C. L., Appelhof, B., Zwijsen, S. A., Smalbrugge, M., Verhey, F. R. J., de Vugt, M. E., Zuidema, S. U., Koopmans, R. T. C. M. & Bakker, C., 1 Mar 2018, In : International Psychogeriatrics. 30, 3, p. 437-446 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Blood-Brain Barrier Dysfunction in Small Vessel Disease Related Intracerebral Hemorrhage

Freeze, W. M., Jacobs, H. I. L., Schreuder, F. H. B. M., van Oostenbrugge, R. J., Backes, W. H., Verhey, F. R. & Klijn, C. J. M., 12 Nov 2018, In : Frontiers in Neurology. 9, 11 p., 926.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Characteristics of double care demanding patients in a mental health care setting and a nursing home setting: results from the SpeCIMeN study

Collet, J., de Vugt, M. E., Verhey, F. R. J., Engelen, N. J. J. A. & Schols, J. M. G. A., 1 Jan 2018, In : Aging & Mental Health. 22, 1, p. 33-39 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Co-occurrence of depressive symptoms and executive dysfunction after stroke: associations with brain pathology and prognosis

Douven, E., Aalten, P., Staals, J., Schievink, S. H. J., van Oostenbrugge, R. J., Verhey, F. R. J. & Kohler, S., 1 Aug 2018, In : Journal of Neurology Neurosurgery and Psychiatry. 89, 8, p. 859-865 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline (vol 9, 101, 2017)

Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Wallin, A. K., van Buchem, M. A., Oleksik, A., Verbeek, M. M., Rikkert, M. O., van der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 20 Jun 2018, In : Alzheimer's Research & Therapy. 10, 3 p., 56.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

Corrigendum: Lifestyle for Brain Health (LIBRA): a new model for dementia prevention (vol 33, pg 167, 2018)

Schiepers, O. J. G., Kohler, S., Deckers, K., Irving, K., O'Donnell, C. A., van den Akker, M., Verhey, F. R. J., Vos, S. J. B., de Vugt, M. E. & van Boxtel, M. P. J., Sep 2018, In : International Journal of Geriatric Psychiatry. 33, 9, p. 1290

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

Effects of a Medication Review on Delirium in Older Hospitalised Patients: A Comparative Retrospective Cohort Study

van Velthuijsen, E. L., Zwakhalen, S. M. G., Pijpers, E., van de Ven, L. I., Ambergen, T., Mulder, W. J., Verhey, F. R. J. & Kempen, G. I. J. M., 1 Feb 2018, In : Drugs & Aging. 35, 2, p. 153-161 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Emotional reactivity to daily life stress in spousal caregivers of people with dementia: An experience sampling study

van Knippenberg, R. J. M., de Vugt, M. E., Ponds, R. W., Verhey, F. R. J. & Myin-Germeys, I., 4 Apr 2018, In : PLOS ONE. 13, 4, 15 p., e0194118.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exploring perspectives of young onset dementia caregivers with high versus low unmet needs

Millenaar, J. K., Bakker, C., van Vliet, D., Koopmans, R. T. C. M., Kurz, A., Verhey, F. R. J. & de Vugt, M. E., 1 Feb 2018, In : International Journal of Geriatric Psychiatry. 33, 2, p. 340-347 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Het bepalen van rijgeschiktheid bij dementie zonder rijtest op de weg

Piersma, D., Fuermaier, A. B. M., De Waard, D., Davidse, R. J., De Groot, J., Doumen, M. J. A., Bredewoud, R. A., Claesen, R., Lemstra, A. W., Vermeeren, A., Ponds, R., Verhey, F., De Deyn, P. P., Tucha, O. & Brouwer, W. H., 17 May 2018, In : Neuropraxis. 22, 3, p. 78-84 7 p.

Research output: Contribution to journalArticleProfessional

High-resolution in vivo imaging of human locus coeruleus by Magnetization Transfer MRI at 3T and 7T

Priovoulos, N., Jacobs, H. I. L., Ivanov, D., Uludag, K., Verhey, F. R. J. & Poser, B. A., Mar 2018, In : Neuroimage. 168, p. 427-436 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Impact of Untimely Access to Formal Care on Costs and Quality of Life in Community Dwelling People with Dementia

Janssen, N., Handels, R. L., Skoldunger, A., Woods, B., Jelley, H., Edwards, R. T., Orrell, M., Selbaek, G., Rosvik, J., Goncalves-Pereira, M., Marques, M. J., Zanetti, O., Portolani, E., Irving, K., Hopper, L., Meyer, G., Bieber, A., Stephan, A., Kerpershoek, L., Wolfs, C. A. G. & 4 others, de Vugt, M. E., Verhey, F. R. J., Wimo, A. & ActifCare Consortium, 1 Jan 2018, In : Journal of Alzheimer's Disease. 66, 3, p. 1165-1174 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Lack of associations between modifiable risk factors and dementia in the very old: findings from the Cambridge City over-75s cohort study

Deckers, K., Köhler, S., van Boxtel, M., Verhey, F., Brayne, C., Fleming, J. & CC75C study collaboration, 2018, In : Aging & Mental Health. 22, 10, p. 1272-1278 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Lifestyle for Brain Health (LIBRA): a new model for dementia prevention

Schiepers, O. J. G., Kohler, S., Deckers, K., Irving, K., O'Donnell, C. A., van den Akker, M., Verhey, F. R. J., Vos, S. J. B., de Vugt, M. E. & van Boxtel, M. P. J., Jan 2018, In : International Journal of Geriatric Psychiatry. 33, 1, p. 167-175 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study

ten Kate, M., Redolfi, A., Peira, E., Bos, I., Vos, S. J., Vandenberghe, R., Gabel, S., Schaeverbeke, J., Scheltens, P., Blin, O., Richardson, J. C., Bordet, R., Wallin, A., Eckerstrom, C., Molinuevo, J. L., Engelborghs, S., Van Broeckhoven, C., Martinez-Lage, P., Popp, J., Tsolaki, M. & 17 others, Verhey, F. R. J., Baird, A. L., Legido-Quigley, C., Bertram, L., Dobricic, V., Zetterberg, H., Lovestone, S., Streffer, J., Bianchetti, S., Novak, G. P., Revillard, J., Gordon, M. F., Xie, Z., Wottschel, V., Frisoni, G., Visser, P. J. & Barkhof, F., 27 Sep 2018, In : Alzheimer's Research & Therapy. 10, 12 p., 100.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Needs and quality of life of people with middle-stage dementia and their family carers from the European Actifcare study. When informal care alone may not suffice

Kerpershoek, L., de Vugt, M., Wolfs, C., Woods, B., Jelley, H., Orrell, M., Stephan, A., Bieber, A., Meyer, G., Selbaek, G., Handels, R., Wimo, A., Hopper, L., Irving, K., Marques, M., Goncalves-Pereira, M., Portolani, E., Zanetti, O., Verhey, F. & ActifCare Consortium, 1 Jan 2018, In : Aging & Mental Health. 22, 7, p. 897-902 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial

Lawlor, B., Segurado, R., Kennelly, S., Rikkert, M. G. M. O., Howard, R., Pasquier, F., Borjesson-Hanson, A., Tsolaki, M., Lucca, U., Molloyid, D. W., Coen, R., Riepe, M. W., Kalman, J., Kenny, R. A., Cregg, F., O'Dwyer, S., Walsh, C., Adams, J., Banzi, R., Breuilh, L. & 26 others, Daly, L., Hendrix, S., Aisen, P., Gaynor, S., Sheikhi, A., Taekema, D. G., Verhey, F. R., Nemni, R., Nobili, F., Franceschi, M., Frisoni, G., Zanetti, O., Konsta, A., Anastasios, O., Nenopoulou, S., Tsolaki-Tagaraki, F., Pakaski, M., Dereeper, O., de la Sayette, V., Senechal, O., Lavenu, I., Devendeville, A., Calais, G., Crawford, F., Mullan, M. & NILVAD Study Grp, 1 Sep 2018, In : PLoS Medicine. 15, 9, 20 p., e1002660.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Nursing Staff Distress Associated With Neuropsychiatric Symptoms in Young-Onset Dementia and Late-Onset Dementia

van Duinen-van den IJssel, J. C. L., Mulders, A. J. M. J., Smalbrugge, M., Zwijsen, S. A., Appelhof, B., Zuidema, S. U., de Vugt, M. E., Verhey, F. R. J., Bakker, C. & Koopmans, R. T. C. M., 1 Jul 2018, In : Journal of the American Medical Directors Association. 19, 7, p. 627-632 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Personality traits and course of symptoms of depression and apathy after stroke: Results of the CASPER study

Douven, E., Staals, J., Schievink, S. H. J., van Oostenbrugge, R. J., Verhey, F. R. J., Wetzels-Meertens, S., Kohler, S. & Aalten, P., 1 Aug 2018, In : Journal of Psychosomatic Research. 111, p. 69-75 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of the apolipoprotein E epsilon 4 allele in amyloid beta positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., Frisoni, G. B., Ivanoiu, A., Chetelat, G., Oliveira, C. R., Rodrigue, K. M., Kornhuber, J., Wallin, A., Klimkowicz-Mrowiec, A., Kandimalla, R., Popp, J. & 75 others, Aalten, P. P., Aarsland, D., Alcolea, D., Almdahl, I. S., Baldeiras, I., Buchem, M. A., Cavedo, E., Chen, K., Cohen, A. D., Foerster, S., Fortea, J., Frederiksen, K. S., Freund-Levi, Y., Gill, K. D., Gkatzima, O., Grimmer, T., Hampel, H., Herukka, S-K., Johannsen, P., Laere, K., Leon, M. J., Maier, W., Marcusson, J., Meulenbroek, O., Mollergard, H. M., Morris, J. C., Mroczko, B., Nordlund, A., Prabhakar, S., Peters, O., Rami, L., Rodriguez-Rodriguez, E., Roe, C. M., Ruther, E., Santana, I., Schroder, J., Seo, S. W., Soininen, H., Spiru, L., Stomrud, E., Struyfs, H., Teunissen, C. E., Verhey, F. R. J., Vos, S. J. B., Doorn, L. J. C. V. W., Waldemar, G., Wallin, A. K., Wiltfang, J., Vandenberghe, R., Brooks, D. J., Fladby, T., Rowe, C. C., Drzezga, A., Verbeek, M. M., Sarazin, M., Wolk, D. A., Fleisher, A. S., Klunk, W. E., Na, D. L., Sanchez-Juan, P., Lee, D. Y., Nordberg, A., Tsolaki, M., Camus, V., Rinne, J. O., Fagan, A. M., Zetterberg, H., Blennow, K., Rabinovici, G. D., Hansson, O., Berckel, B. N. M., Flier, W. M., Scheltens, P., Visser, P. J. & Ossenkoppele, R., 1 Jul 2018, In : Alzheimer's & Dementia. 14, 7, p. 913-924 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Process Evaluation of an Intervention for the Management of Neuropsychiatric Symptoms in Young-Onset Dementia

Appelhof, B., Bakker, C., van Duinen-van den Ijssel, J. C. L., Zwijsen, S. A., Smalbrugge, M., Verhey, F. R. J., de Vugt, M. E., Zuidema, S. U. & Koopmans, R. T. C. M., 1 Aug 2018, In : Journal of the American Medical Directors Association. 19, 8, p. 663-671 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quality of Life, Care Resource Use, and Costs of Dementia in 8 European Countries in a Cross-Sectional Cohort of the Actifcare Study

Handels, R. L. H., Skoldunger, A., Bieber, A., Edwards, R. T., Goncalves-Pereire, M., Hopper, L., Irving, K., Jelley, H., Kerpershoek, L., Marques, M. J., Meyer, G., Michelet, M., Portolani, E., Rosvik, J., Selbaek, G., Stephan, A., de Vugt, M., Wolfs, C., Woods, B., Zanetti, O. & 3 others, Verhey, F., Wimo, A. & ActifCare Consortium, 1 Jan 2018, In : Journal of Alzheimer's Disease. 66, 3, p. 1027-1040 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Shades of white: diffusion properties of T1- and FLAIR-defined white matter signal abnormalities differ in stages from cognitively normal to dementia

Riphagen, J. M., Gronenschild, E. H. B. M., Salat, D. H., Freeze, W. M., Ivanov, D., Clerx, L., Verhey, F. R. J., Aalten, P. & Jacobs, H. I. L., Aug 2018, In : Neurobiology of Aging. 68, p. 48-58 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The clinical course and interrelations of dementia related symptoms

Haaksma, M. L., Leoutsakos, J-M. S., Bremer, J. A. E., Aalten, P., Ramakers, I. H. G. B., Verhey, F. R. J., Rikkert, M. G. M. O. & Melis, R. J. F., 1 Jun 2018, In : International Psychogeriatrics. 30, 6, p. 859-866 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The MMSE should not be the sole indicator of fitness to drive in mild Alzheimer's dementia

Piersma, D., Fuermaier, A. B. M., de Waard, D., De Deyn, P. P., Davidse, R. J., de Groot, J., Doumen, M. J. A., Bredewoud, R. A., Claesen, R., Lemstra, A. W., Vermeeren, A., Ponds, R., Verhey, F., Brouwer, W. H. & Tucha, O., Dec 2018, In : Acta Neurologica Belgica. 118, 4, p. 637–642 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Progression of Dementia and Cognitive Decline in a Dutch 2-Year Cohort Study of People with Young-Onset Dementia

Gerritsen, A. A. J., Bakker, C., Verhey, F. R. J., Bor, H., Pijnenburg, Y. A. L., de Vugt, M. E. & Koopmans, R. T. C. M., 1 Jan 2018, In : Journal of Alzheimer's Disease. 63, 1, p. 343-351 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The use of an electronic clinical rule to discontinue chronically used benzodiazepines and related Z drugs

Gonzalvo, C. M., Milosevic, V., van Oijen, B. P. C., de Wit, H. A. J. M., Hurkens, K. P. G. M., Mulder, W. J., Janknegt, R., Schols, J. M. G. A., Verhey, F. R., Winkens, B. & van der Kuy, P. H. M., 1 Feb 2018, In : European Journal of Clinical Pharmacology. 74, 2, p. 227-231 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Well-being of nursing staff on specialized units for older patients with combined care needs

Collet, J., de Vugt, M. E., Schols, J. M. G. A., Engelen, G. J. J. A., Winkens, B. & Verhey, F. R. J., 1 Mar 2018, In : Journal of Psychiatric and Mental Health Nursing. 25, 2, p. 108-118 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017
Open Access

A first step toward integrating schema theory in geriatric psychiatry: a Delphi study

Legra, M. J. H., Verhey, F. R. J. & van Alphen, S. P. J., Jul 2017, In : International Psychogeriatrics. 29, 7, p. 1069-1076 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Assessing fitness to drive - A validation study on patients with Mild Cognitive Impairment

Fuermaier, A. B. M., Piersma, D., de Waard, D., Davidse, R. J., de Groot, J., Doumen, M. J. A., Bredewoud, R. A., Claesen, R., Lemstra, A. W., Scheltens, P., Vermeeren, A., Ponds, R., Verhey, F., Brouwer, W. H. & Tucha, O., 2017, In : Traffic Injury Prevention. 18, 2, p. 145-149 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Assessing the strengths and weaknesses of a computer assisted medication review in hospitalized patients

Hurkens, K. P. G. M., Mestres-gonzalvo, C., Wit, H. A. J. M. D., Janknegt, R., Verhey, F., Schols, J. M. G. A., Magdelijns, F., Stehouwer, C. D. A., Winkens, B., Mulder, W. & Kuy, P. H. M. V. D., 2017, In : International Journal of Hospital Pharmacy. 2, 6, p. 1-12 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study

Reijs, B. L. R., Vos, S. J. B., Soininen, H., Lotjonen, J., Koikkalainen, J., Pikkarainen, M., Hall, A., Vanninen, R., Liu, Y., Herukka, S-K., Freund-Levi, Y., Frisoni, G. B., Frolich, L., Nobilij, F., Rikkert, M. O., Spiru, L., Tsolaki, M., Wallinn, A. K., Scheltens, P., Verhey, F. & 1 others, Visser, P. J., 2017, In : Journal of Alzheimer's Disease. 60, 4, p. 1387-1395 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Author response: Dementia risk in renal dysfunction: A systematic review and meta-analysis of prospective studies

Deckers, K., Camerino, I., van Boxtel, M. P. J., Verhey, F. R. J., Irving, K., Brayne, C., Kivipelto, M., Starr, J. M., Yaffe, K., de Leeuw, P. W. & Kohler, S., 21 Nov 2017, In : Neurology. 89, 21, p. 2214-2215

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Caregiver profiles in dementia related to quality of life, depression and perseverance time in the European Actifcare study: the importance of social health

Janssen, E. P. C. J., de Vugt, M., Kohler, S., Wolfs, C., Kerpershoek, L., Handels, R. L. H., Orrell, M., Woods, B., Jelley, H., Stephan, A., Bieber, A., Meyer, G., Engedal, K., Selbaek, G., Wimo, A., Irving, K., Hopper, L., Marques, M., Goncalves-Pereira, M., Portolani, E. & 2 others, Zanetti, O. & Verhey, F. R., 2017, In : Aging & Mental Health. 21, 1, p. 49-57 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Wallin, A. K., van Buchem, M. A., Oleksik, A., Verbeek, M. M., Rikkert, M. O., van der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 29 Dec 2017, In : Alzheimer's Research & Therapy. 9, 10 p., 101.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Coronary heart disease and risk for cognitive impairment or dementia: Systematic review and meta-analysis

Deckers, K., Schievink, S. H. J., Rodriquez, M. M. F., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J. & Kohler, S., 8 Sep 2017, In : PLOS ONE. 12, 9, e0184244.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cost-Utility of Using Alzheimer's Disease Biomarkers in Cerebrospinal Fluid to Predict Progression from Mild Cognitive Impairment to Dementia

Handels, R. L. H., Wimo, A., Dodel, R., Kramberger, M. G., Visser, P. J., Luis Molinuevo, J., Verhey, F. R. J. & Winblad, B., 7 Nov 2017, In : Journal of Alzheimer's Disease. 60, 4, p. 1477-1487 11 p.

Research output: Contribution to journalArticleAcademicpeer-review