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Research Output 2010 2019

2019

An orthotopic non-small cell lung cancer model for image-guided small animal radiotherapy platforms

Iglesias, V. S., van Hoof, S. J., Vaniqui, A., Schyns, L. E., Lieuwes, N., Yaromina, A., Spiegelberg, L., Groot, A. J., Verhaegen, F., Theys, J., Dubois, L. & Vooijs, M., 2019, In : British Journal of Radiology. 92, 1095, 10 p., 20180476.

Research output: Contribution to journalArticleAcademicpeer-review

A novel data management platform to improve image-guided precision preclinical biological research

Persoon, L., van Hoof, S., van der Kruijssen, F., Granton, P., Rivero, A. S., Beunk, H., Dubois, L., Doosje, J-W. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 7 p., 20180455.

Research output: Contribution to journalArticleAcademicpeer-review

A systematic review comparing radiation toxicity after various endorectal techniques

Verrijssen, A-S., Opbroek, T., Bellezzo, M., Fonseca, G. P., Verhaegen, F., Gerard, J-P., Myint, A. S., Van Limbergen, E. J. & Berbee, M., 2019, In : Brachytherapy. 18, 1, p. 71-86 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Automatic multiatlas based organ at risk segmentation in mice

Van Der Heyden, B., Podesta, M., Eekers, D. B. P., Vaniqui, A., Almeida, I. P., Schyns, L. E. J. R., Van Hoof, S. J. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 7 p., 20180364.

Research output: Contribution to journalArticleAcademicpeer-review

Corrigendum to A systematic review comparing radiation toxicity after various endorectal techniques (vol 18, pg 71, 2019)

Verrijssen, A-S., Opbroek, T., Bellezzo, M., Fonseca, G. P., Verhaegen, F., Gerard, J-P., Myint, A. S., Van Limbergen, E. J. & Berbee, M., 2019, In : Brachytherapy. 18, 3, p. 427-427 1 p.

Research output: Contribution to journalErratum / corrigendumAcademic

Dose painting by dynamic irradiation delivery on an image-guided small animal radiotherapy platform

Van Hoof, S. J., Verde, J. B. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 11 p., 20180744.

Research output: Contribution to journalArticleAcademicpeer-review

Dose to water versus dose to medium from cavity theory applied to small animal irradiation with kilovolt x-rays

Vaniqui, A., Walters, B. R., Fonseca, G. P. & Verhaegen, F., Aug 2019, In : Physics in Medicine and Biology. 64, 16, 14 p., 165001.

Research output: Contribution to journalArticleAcademicpeer-review

Dual-energy CT for automatic organs-at-risk segmentation in brain-tumor patients using a multi-atlas and deep-learning approach

van der Heyden, B., Wohlfahrt, P., Eekers, D. B. P., Richter, C., Terhaag, K., Troost, E. G. C. & Verhaegen, F., 11 Mar 2019, In : Scientific Reports. 9, p. 1-9 9 p., 4126.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exploring the feasibility of a clinical proton beam with an adaptive aperture for pre-clinical research

Almeida, I. P., Vaniqui, A., Schyns, L. E., van der Heyden, B., Cooley, J., Zwart, T., Langenegger, A. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 9 p., 20180446.

Research output: Contribution to journalArticleAcademicpeer-review

Mechanical evaluation of the Bravos afterloader system for HDR brachytherapy

Bellezzo, M., Baeza, J. A., Voncken, R., Reniers, B., Verhaegen, F. & Fonseca, G. P., 18 Jul 2019, In : Brachytherapy. 18, 6, p. 852-862 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Murine vs human tissue compositions: implications of using human tissue compositions for photon energy absorption in mice

Schyns, L. E. J. R., Eekers, D. B. P., Van Der Heyden, B., Almeida, I. P., Vaniqui, A. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 8 p., 20180454.

Research output: Contribution to journalArticleAcademicpeer-review

On the determination of planning target margins due to motion for mice lung tumours using a four-dimensional MOBY phantom

Vaniqui, A., van der Heyden, B., Almeida, I. P., Schyns, L. E., van Hoof, S. J. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 9 p., 20180445.

Research output: Contribution to journalArticleAcademicpeer-review

The effect of different image reconstruction techniques on pre-clinical quantitative imaging and dual-energy CT

Vaniqui, A., Schyns, L. E. J. R., Almeida, I. P., van der Heyden, B., Podesta, M. & Verhaegen, F., 2019, In : British Journal of Radiology. 92, 1095, 11 p., 20180447.

Research output: Contribution to journalArticleAcademicpeer-review

The role of external beam and endoluminal radiation boosting in rectal cancer

Berbee, M., Verrijssen, A-S., Buijsen, J., Verhaegen, F. & Van Limbergen, E. J., Mar 2019, In : Colorectal Cancer. 8, 1, 4 p., 07.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
2018

Altered protein turnover signaling and myogenesis during impaired recovery of inflammation-induced muscle atrophy in emphysematous mice

Ceelen, J. J. M., Schols, A. M. W. J., Kneppers, A. E. M., Rosenbrand, R. P. H. A., Drozdz, M. M., van Hoof, S. J., de Theije, C. C., Kelders, M. C. J. M., Verhaegen, F. & Langen, R. C. J., 17 Jul 2018, In : Scientific Reports. 8, 12 p., 10761.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A novel approach to EPID-based 3D volumetric dosimetry for IMRT and VMAT QA

Alhazmi, A., Gianoli, C., Neppl, S., Martins, J., Veloza, S., Podesta, M., Verhaegen, F., Reiner, M., Belka, C. & Parodi, K., 1 Jun 2018, In : Physics in Medicine and Biology. 63, 11, 13 p., 115002.

Research output: Contribution to journalArticleAcademicpeer-review

A novel rectal applicator for contact radiotherapy with HDR Ir-192 sources

Bellezzo, M., Fonseca, G. P., Verrijssen, A-S., Voncken, R., Van den Bosch, M. R., Yoriyaz, H., Reniers, B., Berbee, M., Van Limbergen, E. J. & Verhaegen, F., 2018, In : Brachytherapy. 17, 6, p. 1037-1044 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Automated patient-specific transperineal ultrasound probe setups for prostate cancer patients undergoing radiotherapy

Camps, S. M., Verhaegen, F., Vanneste, B. G. L., de With, P. H. N. & Fontanarosa, D., Jul 2018, In : Medical Physics. 45, 7, p. 3185-3195 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Development of an Image-Guided Orthotopic Xenograft Mouse Model of Endometrial Cancer with Controllable Estrogen Exposure

Konings, G. F. J., Saarinen, N., Delvoux, B., Kooreman, L., Koskimies, P., Krakstad, C., Fasmer, K. E., Haldorsen, I. S., Zaffagnini, A., Hakkinen, M. R., Auriola, S., Dubois, L., Lieuwes, N., Verhaegen, F., Schyns, L. E. J. R., Kruitwagen, R. F. P. M., Xanthoulea, S. & Romano, A., Sep 2018, In : International journal of molecular sciences. 19, 9, 16 p., 2547.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

ESTRO ACROP: Technology for precision small animal radiotherapy research: Optimal use and challenges

Verhaegen, F., Dubois, L., Gianolini, S., Hill, M. A., Karger, C. P., Lauber, K., Prise, K. M., Sarrut, D., Thorwarth, D., Vanhove, C., Vojnovic, B., Weersink, R., Wilkens, J. J. & Georg, D., 1 Mar 2018, In : Radiotherapy and Oncology. 126, 3, p. 471-478 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Monte Carlo proton dose calculations using a radiotherapy specific dual-energy CT scannerfortissue segmentation and range assessment

Almeida, I. P., Schyns, L. E. J. R., Vaniqui, A., van der Heyden, B., Dedes, G., Resch, A. F., Kamp, F., Zindler, J. D., Parodi, K., Landry, G. & Verhaegen, F., 1 Jun 2018, In : Physics in Medicine and Biology. 63, 11, 14 p., 115008.

Research output: Contribution to journalArticleAcademicpeer-review

Reply to: "Comment on: Dual-energy CT quantitative imaging: A comparison study between twin-beam and dual-source CT scanners [Med. Phys. 44(1), 171-179 (2017)]"

Almeida, I. P., Landry, G., van Elmpt, W., Parodi, K. & Verhaegen, F., Aug 2018, In : Medical Physics. 45, 8, p. 3997-3998 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Revisiting the single-energy CT calibration for proton therapy treatment planning: a critical look at the stoichiometric method

Goma, C., Almeida, I. P. & Verhaegen, F., Dec 2018, In : Physics in Medicine and Biology. 63, 23, 13 p., 235011.

Research output: Contribution to journalArticleAcademicpeer-review

Should dose from small fields be limited for dose verification procedures? uncertainty versus small field dose in VMAT treatments

Wolfs, C. J. A., Swinnen, A. C. C., Nijsten, S. M. J. J. G. & Verhaegen, F., Oct 2018, In : Physics in Medicine and Biology. 63, 20, 5 p., ARTN 20NT01.

Research output: Contribution to journalArticleAcademicpeer-review

The influence of tissue composition uncertainty on dose distributions in brachytherapy

Mann-Krzisnik, D., Verhaegen, F. & Enger, S. A., 1 Mar 2018, In : Radiotherapy and Oncology. 126, 3, p. 394-410 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

The Use of Ultrasound Imaging in the External Beam Radiotherapy Workflow of Prostate Cancer Patients

Camps, S. M., Fontanarosa, D., de With, P. H. N., Verhaegen, F. & Vanneste, B. G. L., 1 Jan 2018, In : BioMed Research International. 2018, 16 p., 7569590.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Towards a Clinical Decision Support System for External Beam Radiation Oncology Prostate Cancer Patients: Proton vs. Photon Radiotherapy? A Radiobiological Study of Robustness and Stability

Walsh, S., Roelofs, E., Kuess, P., van Wijk, Y., Vanneste, B., Dekker, A., Lambin, P., Jones, B., Georg, D. & Verhaegen, F., 1 Feb 2018, In : Cancers. 10, 2, 16 p., 55.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Validation and uncertainty analysis of a pre-treatment 2D dose prediction model

Baeza, J. A., Wolfs, C. J. A., Nijsten, S. M. J. J. G. & Verhaegen, F., 1 Feb 2018, In : Physics in Medicine and Biology. 63, 3, 13 p., 035033.

Research output: Contribution to journalArticleAcademicpeer-review

2017

A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy

Ma, Y., Vijande, J., Ballester, F., Tedgren, A. C., Granero, D., Haworth, A., Mourtada, F., Fonseca, G. P., Zourari, K., Papagiannis, P., Rivard, M. J., Siebert, F-A., Sloboda, R. S., Smith, R., Chamberland, M. J. P., Thomson, R. M., Verhaegen, F. & Beaulieu, L., Nov 2017, In : Medical Physics. 44, 11, p. 5961-5976 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

A novel system for commissioning brachytherapy applicators: example of a ring applicator

Fonseca, G. P., Van den Bosch, M. R., Voncken, R., Podesta, M. & Verhaegen, F., 7 Nov 2017, In : Physics in Medicine and Biology. 62, 21, p. 8360-8375 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Application of single- and dual-energy CT brain tissue segmentation to PET monitoring of proton therapy

Berndt, B., Landry, G., Schwarz, F., Tessonnier, T., Kamp, F., Dedes, G., Thieke, C., Wrl, M., Kurz, C., Ganswindt, U., Verhaegen, F., Debus, J., Belka, C., Sommer, W., Reiser, M., Bauer, J. & Parodi, K., 27 Feb 2017, In : Physics in Medicine and Biology. 62, 6, p. 2427-2448 22 p.

Research output: Contribution to journalArticleAcademicpeer-review

Clinical evaluation of a novel CT image reconstruction algorithm for direct dose calculations

van der Heyden, B., Ollers, M., Ritter, A., Verhaegen, F. & van Elmpt, W., Mar 2017, In : Physics & Imaging in Radiation Oncology. 2, p. 11-16 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Detection of anatomical changes in lung cancer patients with 2D time-integrated, 2D time-resolved and 3D time-integrated portal dosimetry: a simulation study

Wolfs, C. J. A., Bras, M. G., Schyns, L. E. J. R., Nijsten, S. M. J. J. G., van Elmpt, W., Scheib, S. G., Baltes, C., Podesta, M. & Verhaegen, F., 7 Aug 2017, In : Physics in Medicine and Biology. 62, 15, 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammation

Ceelen, J. J. M., Schols, A. M. W. J., van Hoof, S. J., de Theije, C. C., Verhaegen, F. & Langen, R. C. J., 2 May 2017, In : Respiratory Research. 18, 10 p., 75.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Dual-energy CT quantitative imaging: a comparison study between twin-beam and dual-source CT scanners

Almeida, I. P., Schyns, L. E. J. R., Ollers, M. C., van Elmpt, W., Parodi, K., Landry, G. & Verhaegen, F., Jan 2017, In : Medical Physics. 44, 1, p. 171-179 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

EVALUATING CLINICAL STOPPING POWER ESTIMATION FROM A RADIOTHERAPY DUAL ENERGY CT SCANNER

Almeida, I. P., Landry, G., Dedes, G., Patel, R., Pankuch, M., Coutrakon, G., Schulte, R., Verhaegen, F., Parodi, K. & Roeske, J. C., Oct 2017, In : Acta Physica Polonica B. 48, 10, p. 1619-1623 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Evaluation of Optical Localization in the Visible Band for Ultrasound Guidance in Radiotherapy Using A Robotic Arm

Camps, S. M., Costa, M., Stevens, E., Sanches, P. G., Paiva Fonseca, G., Bellezzo, M., Verhaegen, F. & Fontanarosa, D., 2017, In : Journal of Cancer Control and Treatment. 30, 5, p. 319-329 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Influence of the jaw tracking technique on the dose calculation accuracy of small field VMAT plans

Swinnen, A. C. C., Ollers, M. C., Roijen, E., Nijsten, S. M. & Verhaegen, F., Jan 2017, In : Journal of Applied Clinical Medical Physics. 18, 1, p. 186-195 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Online pretreatment verification of high-dose rate brachytherapy using an imaging panel

Fonseca, G. P., Podesta, M., Bellezzo, M., Van den Bosch, M. R., Lutgens, L., Vanneste, B. G. L., Voncken, R., Van Limbergen, E. J., Reniers, B. & Verhaegen, F., 7 Jul 2017, In : Physics in Medicine and Biology. 62, 13, p. 5440-5461 22 p.

Research output: Contribution to journalArticleAcademicpeer-review

Optimizing dual energy cone beam CT protocols for preclinical imaging and radiation research

Schyns, L. E. J. R., Almeida, I. P., van Hoof, S. J., Descamps, B., Vanhove, C., Landry, G., Granton, P. V. & Verhaegen, F., 2017, In : British Journal of Radiology. 90, 1069, 10 p., 20160480.

Research output: Contribution to journalArticleAcademicpeer-review

Small animal image-guided radiotherapy

Prise, K. M. & Verhaegen, F., 2017, In : British Journal of Radiology. 90, 1069, 2 p., 20160905.

Research output: Contribution to journalEditorialAcademicpeer-review

The impact of dual energy CT imaging on dose calculations for pre-clinical studies

Vaniqui, A., Schyns, L. E. J. R., Almeida, I. P., van der Heyden, B., van Hoof, S. J. & Verhaegen, F., 21 Nov 2017, In : Radiation Oncology. 12, 15 p., 181.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The influence of respiratory motion on dose delivery in a mouse lung tumour irradiation using the 4D MOBY phantom

van der Heyden, B., van Hoof, S. J., Schyns, L. E. J. R. & Verhaegen, F., 2017, In : British Journal of Radiology. 90, 1069, 11 p., 20160419.

Research output: Contribution to journalArticleAcademicpeer-review

Three-dimensional dose evaluation in breast cancer patients to define decision criteria for adaptive radiotherapy

Zegers, C. M. L., Baeza, J. A., van Elmpt, W., Murrer, L. H. P., Verhoeven, K., Boersma, L., Verhaegen, F. & Nijsten, S. M. J. J. G., Nov 2017, In : Acta Oncologica. 56, 11, p. 1487-1494 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tissue sensitive imaging and tomography without contrast agents for small animals with Timepix based detectors

Trojanova, E., Schyns, L. E. J. R., Dubois, L., Jakubek, J., Le Pape, A., Sefc, L., Sykora, V., Turecek, D., Uher, J. & Verhaegen, F., Jan 2017, In : Journal of Instrumentation. 12, 9 p., 01056.

Research output: Contribution to journalArticleAcademicpeer-review

Tumour and normal tissue radiobiology in mouse models: how close are mice to mini-humans?

Koontz, B. F., Verhaegen, F. & De Ruysscher, D., 2017, In : British Journal of Radiology. 90, 1069, 7 p., 20160441.

Research output: Contribution to journalReview articleAcademicpeer-review

2016

Accuracy of dose calculations on kV cone beam CT images of lung cancer patients

de Smet, M., Schuring, D., Nijsten, S. & Verhaegen, F., Nov 2016, In : Medical Physics. 43, 11, p. 5934-5941

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

A comparison of the relative biological effectiveness of low energy electronic brachytherapy sources in breast tissue: a Monte Carlo study

White, S. A., Reniers, B., de Jong, E. E. C., Rusch, T. & Verhaegen, F., 7 Jan 2016, In : Physics in Medicine and Biology. 61, 1, p. 383-399

Research output: Contribution to journalArticleAcademicpeer-review