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Research Output 2009 2019

Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms

Botschuijver, S., van Diest, S. A., van Thiel, I. A. M., Saia, R. S., Strik, A. S., Yu, Z., Maria-Ferreira, D., Welting, O., Keszthelyi, D., Jennings, G., Heinsbroek, S. E. M., Elferink, R. P. O., Schuren, F. H. J., de Jonge, W. J. & van den Wijngaard, R. M., 29 Aug 2019, In : Scientific Reports. 9, 11 p., 12530.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Role of TRPV1 and TRPA1 Ion Channels in Inflammatory Bowel Diseases: Potential Therapeutic Targets?

Cseko, K., Beckers, B., Keszthelyi, D. & Helyes, Z., Jun 2019, In : Pharmaceuticals. 12, 2, p. 1-19 19 p., 48.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The Experience Sampling Method-Evaluation of treatment effect of escitalopram in IBS with comorbid panic disorder

Vork, L., Mujagic, Z., Drukker, M., Keszthelyi, D., Conchillo, J. M., Hesselink, M. A. M., van Os, J., Masclee, A. A. M., Leue, C. & Kruimel, J. W., Jan 2019, In : Neurogastroenterology and Motility. 31, 1, 9 p., 13515.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2018

A Novel Ileocolonic Release Peppermint Oil Capsule for Treatment of Irritable Bowel Syndrome: A Phase I Study in Healthy Volunteers

Weerts, Z. Z. R. M., Keszthelyi, D., Vork, L., Aendekerk, N. C. P., Frijlink, H. W., Brouwers, J. R. B. J., Neef, C., Jonkers, D. M. A. E. & Masclee, A. A. M., Nov 2018, In : Advances in Therapy. 35, 11, p. 1965–1978 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Delineation between different components of chronic pain using dimension reduction - an ASL fMRI study in hand osteoarthritis

Keszthelyi, D., Aziz, Q., Ruffle, J. K., O'Daly, O., Sanders, D., Krause, K., Williams, S. C. R. & Howard, M. A., 1 Aug 2018, In : European Journal of Pain. 22, 7, p. 1245-1254 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Development, content validity, and cross-cultural adaptation of a patient-reported outcome measure for real-time symptom assessment in irritable bowel syndrome

Vork, L., Keszthelyi, D., Mujagic, Z., Kruimel, J. W., Leue, C., Ponten, I., Tornblom, H., Simren, M., Albu-Soda, A., Aziz, Q., Corsetti, M., Holvoet, L., Tack, J., Rao, S. S., van Os, J., Quetglas, E. G., Drossman, D. A. & Masclee, A. A. M., Mar 2018, In : Neurogastroenterology and Motility. 30, 3, 10 p., 13244.

Research output: Contribution to journalArticleAcademicpeer-review

Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome

Vila, A. V., Imhann, F., Collij, V., Jankipersadsing, S. A., Gurry, T., Mujagic, Z., Kurilshikov, A., Bonder, M. J., Jiang, X., Tigchelaar, E. F., Dekens, J., Peters, V., Voskuil, M. D., Visschedijk, M. C., van Dullemen, H. M., Keszthelyi, D., Swertz, M. A., Franke, L., Alberts, R., Festen, E. A. M. & 10 others, Dijkstra, G., Masclee, A. A. M., Hofker, M. H., Xavier, R. J., Alm, E. J., Fu, J., Section, C. W., Section, D. M. A. E. J., Zhernakova, A. & Weersma, R. K., 19 Dec 2018, In : Science Translational Medicine. 10, 472, 11 p., 8914.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Percutaneous endoscopic colostomy for adults with chronic constipation: Retrospective case series of 12 patients

Strijbos, D., Keszthelyi, D., Masclee, A. A. M. & Gilissen, L. P. L., May 2018, In : Neurogastroenterology and Motility. 30, 5, 7 p., 13270.

Research output: Contribution to journalArticleAcademicpeer-review

The Effect of an Encapsulated Nutrient Mixture on Food Intake and Satiety: A Double-Blind Randomized Cross-Over Proof of Concept Study

Alleleyn, A. M. E., van Avesaat, M., Ripken, D., Bleiel, S. B., Keszthelyi, D., Wilms, E., Troost, F. J., Hendriks, H. F. J. & Masclee, A. A. M., Nov 2018, In : Nutrients. 10, 11, 12 p., 1787.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

AGE-RELATED CHANGES IN ABDOMINAL PAIN IN HEALTHY INDIVIDUALS AND IBS PATIENTS

Wilms, E., Jonkers, D., Keszthelyi, D., Mujagic, Z., Vork, L., Weerts, Z. Z., Kruimel, J. W., Troost, F. & Masclee, A., Apr 2017, In : Gastroenterology. 152, 5, p. S647-S647 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

A magnetic resonance imaging study of gastric motor function in patients with dyspepsia associated with Ehlers-Danlos Syndrome-Hypermobility Type: A feasibility study

Menys, A., Keszthelyi, D., Fitzke, H., Fikree, A., Atkinson, D., Aziz, Q. & Taylor, S. A., Sep 2017, In : Neurogastroenterology and Motility. 29, 9, 9 p., e13090.

Research output: Contribution to journalArticleAcademicpeer-review

Biomarkers for visceral hypersensitivity in patients with irritable bowel syndrome

Mujagic, Z., Jonkers, D. M. A. E., Ludidi, S., Keszthelyi, D., Hesselink, M. A., Kievit, R. N., Althof, J. F., Weerts, Z. Z. R. M., Kruimel, J. W., Van Schooten, F. J. & Masclee, A. A. M., Dec 2017, In : Neurogastroenterology and Motility. 29, 12, 8 p., e13137.

Research output: Contribution to journalArticleAcademicpeer-review

Clinical Implications of Diagnosing Irritable Bowel Syndrome: Do All Roads Need to Lead to Rome?

Keszthelyi, D. & Ringel, Y., Jun 2017, In : American Journal of Gastroenterology. 112, 6, p. 900-902 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Exploration of the Esophageal Mucosal Barrier in Non-Erosive Reflux Disease

Rinsma, N. F., Farre, R., Troost, F. J., Elizalde, M., Keszthelyi, D., Helyes, Z., Masclee, A. A. & Conchillo, J. M., May 2017, In : International journal of molecular sciences. 18, 5, 12 p., 1091.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gastrointestinal disorders in joint hypermobility syndrome/Ehlers-Danlos syndrome hypermobility type: A review for the gastroenterologist

Beckers, A. B., Keszthelyi, D., Fikree, A., Vork, L., Masclee, A., Farmer, A. D. & Aziz, Q., Aug 2017, In : Neurogastroenterology and Motility. 29, 8, 10 p., e13013.

Research output: Contribution to journalReview articleAcademicpeer-review

Percutaneous endoscopic gastrostomy under conscious sedation in patients with amyotrophic lateral sclerosis is safe: an observational study

Strijbos, D., Hofstede, J., Keszthelyi, D., Masclee, A. A. M. & Gilissen, L. P. L., Nov 2017, In : European Journal of Gastroenterology & Hepatology. 29, 11, p. 1303-1308 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Review article: transient receptor potential channels as possible therapeutic targets in irritable bowel syndrome

Beckers, A. B., Weerts, Z. Z. R. M., Helyes, Z., Masclee, A. A. M. & Keszthelyi, D., Nov 2017, In : Alimentary Pharmacology & Therapeutics. 46, 10, p. 938-952 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2016
4 Citations (Scopus)

Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones

van Avesaat, M., Troost, F. J., Westerterp-Plantenga, M. S., Helyes, Z., le Roux, C. W., Dekker, J., Masclee, A. A. & Keszthelyi, D., Feb 2016, In : American Journal of Clinical Nutrition. 103, 2, p. 305-313 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Dilation in achalasia - is normal distensibility enough: Author's reply

Smeets, F. G. M., Masclee, A. A., Keszthelyi, D., Tjwa, E. T. & Conchillo Armendariz, J., 1 Jan 2016, In : Neurogastroenterology and Motility. 28, 1, p. 154-155 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Translational Difficulties in Studying the TRPA1 Receptor

Keszthelyi, D., van Avesaat, M., Troost, F. J. & Masclee, A. A., Dec 2016, In : Nutrients. 8, 12, 790.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access
1 Citation (Scopus)

Tricyclic Antidepressants: What to Choose and Which Dose?

Keszthelyi, D. & Masclee, A. A., Jul 2016, In : American Journal of Gastroenterology. 111, 7, p. 1035-1036

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

9 Citations (Scopus)

Esophagogastric junction distensibility in the management of achalasia patients: relation to treatment outcome

Smeets, F. G. M., Masclee, A. A., Keszthelyi, D., Tjwa, E. T. & Conchillo, J. M., Oct 2015, In : Neurogastroenterology and Motility. 27, 10, p. 1495-1503 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

14 Citations (Scopus)
3 Citations (Scopus)

Systematic review: instruments to assess abdominal pain in irritable bowel syndrome

Mujagic, Z., Keszthelyi, D., Aziz, Q., Reinisch, W., Quetglas, E. G., De Leonardis, F., Segerdahl, M. & Masclee, A. A., Nov 2015, In : Alimentary Pharmacology & Therapeutics. 42, 9, p. 1064-1081 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

The Experience Sampling Method - a new digital tool for momentary symptom assessment in IBS: an exploratory study

Mujagic, Z., Leue, C., Vork, L., Lousberg, R., Jonkers, D. M. A. E., Keszthelyi, D., Hesselink, M. A., van Schagen, T. J., van Os, J., Masclee, A. A. & Kruimel, J. W., Sep 2015, In : Neurogastroenterology and Motility. 27, 9, p. 1295-1302 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease

Quetglas, E. G., Mujagic, Z., Wigge, S., Keszthelyi, D., Wachten, S., Masclee, A. & Reinisch, W., 28 Nov 2015, In : World Journal of Gastroenterology. 21, 44, p. 12519-12543 25 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism - a preliminary study

Keszthelyi, D., Troost, F. J., Jonkers, D. M., van Eijk, H. M., Dekker, J., Buurman, W. A. & Masclee, A. A. M., Aug 2015, In : Neurogastroenterology and Motility. 27, 8, p. 1127-1137 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2014
1 Citation (Scopus)

Capsaicin stimulation in irritable bowel syndrome: toward understanding visceral perception and pain symptom generation

Keszthelyi, D. & Masclee, A., 1 Jan 2014, In : American Journal of Gastroenterology. 109, 8, p. 1286

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

14 Citations (Scopus)

Ethanol Impairs Intestinal Barrier Function in Humans through Mitogen Activated Protein Kinase Signaling: A Combined In Vivo and In Vitro Approach

Elamin, E., Masclee, A., Troost, F., Pieters, H. J., Keszthelyi, D., Aleksa, K., Dekker, J. & Jonkers, D., 16 Sep 2014, In : PLOS ONE. 9, 9, 11 p., e107421.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Markers for visceral hypersensitivity in patients with irritable bowel syndrome

Ludidi, S., Mujagic, Z., Jonkers, D., Keszthelyi, D., van der Hesselink-Kruijs, M. A. M., Kruimel, J., Conchillo, J. M. & Masclee, A., 1 Jan 2014, In : Neurogastroenterology and Motility. 26, 8, p. 1104-1111

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome

Keszthelyi, D., Troost, F. J., Jonkers, D. M., van Eijk, H. M., Lindsey, P. J., Dekker, J., Buurman, W. & Masclee, A. A., Aug 2014, In : Alimentary Pharmacology & Therapeutics. 40, 4, p. 392-402 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)
216 Downloads (Pure)
Open Access
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2013
19 Citations (Scopus)

Alterations in mucosal neuropeptides in patients with irritable bowel syndrome and ulcerative colitis in remission: A role in pain symptom generation?

Keszthelyi, D., Troost, F. J., Jonkers, D. M. A. E., Helyes, Z., Hamer, H. M. H., Ludidi, S., Vanhoutvin, S. A. L. W., Venema, K., Dekker, J., Szolcsanyi, J. & Masclee, A. A. M., Oct 2013, In : European Journal of Pain. 17, 9, p. 1299-1306 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Letter: lansoprazole consumption is more common in Japanese patients collagenous colitis - authors' reply

Keszthelyi, D. & Masclee, A. A. M., Jul 2013, In : Alimentary Pharmacology & Therapeutics. 38, 2, p. 209-210 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

4 Citations (Scopus)

Letter: the role of sub-clinical inflammation and TRPV1 in the development of IBS-like symptoms in ulcerative colitis in remission

Keszthelyi, D., Jonkers, D. M., Hamer, H. M. & Masclee, A. A., 1 Jan 2013, In : Alimentary Pharmacology & Therapeutics. 38, 5, p. 560-561

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

7 Citations (Scopus)

Time of ingestion relative to meal intake determines gastrointestinal responses to a plant sterol-containing yoghurt drink.

Keszthelyi, D., Knol, D., Troost, F. J., van Avesaat, M., Foltz, M. & Masclee, A. A. M., Jun 2013, In : European Journal of Nutrition. 52, 4, p. 1417-1420 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

2012
16 Citations (Scopus)

Does acute tryptophan depletion affect peripheral serotonin metabolism in the intestine?

Keszthelyi, D., Troost, F. J., Jonkers, D. M. A. E., van Donkelaar, E. L., Dekker, J., Buurman, W. A. & Masclee, A. A. M., 1 Jan 2012, In : American Journal of Clinical Nutrition. 95, 3, p. 603-608

Research output: Contribution to journalArticleAcademicpeer-review