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Research Output 1998 2020

Open Access

Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study

Denissen, K. F. M., Boonen, A., Nielen, J. T. H., Feitsma, A. L., van den Heuvel, E. G. H. M., Emans, P. J., Stehouwer, C. D. A., Sep, S. J. S., van Dongen, M. C. J. M., Dagnelie, P. C. & Eussen, S. J. P. M., Oct 2019, In : European Journal of Nutrition. 58, 7, p. 2693-2704 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Dynamic sitting: Measurement and associations with metabolic health

van der Berg, J. D., Stehouwer, C. D. A., Bosma, H., Caserotti, P., Eiriksdottir, G., Arnardottir, N. Y., Van Domelen, D. R., Brychta, R. J., Chen, K. Y., Sveinsson, T., Johannsson, E., Launer, L. J., Gudnason, V., Jonsson, P. V., Harris, T. B. & Koster, A., 3 Aug 2019, In : Journal of Sports Sciences. 37, 15, p. 1746-1754 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

15 Oct 2019, In : Biological Psychiatry. 86, 8, p. 599-607 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children

Zhong, H., Penders, J., Shi, Z., Ren, H., Cai, K., Fang, C., Ding, Q., Thijs, C., Blaak, E. E., Stehouwer, C. D. A., Xu, X., Yang, H., Wang, J., Wang, J., Jonkers, D. M. A. E., Masclee, A. A. M., Brix, S., Li, J., Arts, I. C. W. & Kristiansen, K., 4 Jan 2019, In : Microbiome. 7, 14 p., 2.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study

Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A. & Brouwers, M. C. G. J., Jan 2019, In : Atherosclerosis. 280, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

Onderwater, G. L. J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., van der Kallen, C. J. H., Vijfhuizen, L. S., Pool, R., Liu, J., Vanmolkot, F. H. M., Beekman, M., Wen, K., Amin, N., Thesing, C. S., Pijpers, J. A., Kies, D. A., Zielman, R., de Boer, I., van Greevenbroek, M. M. J., Arts, I. C. W. & 16 others, Milaneschi, Y., Schram, M. T., Dagnelie, P. C., Franke, L., Ikram, M. A., Ferrari, M. D., Goeman, J. J., Slagboom, P. E., Wijmenga, C., Stehouwer, C. D. A., Boomsma, D. I., van Duijn, C. M., Penninx, B. W., 't Hoen, P. A. C., Terwindt, G. M. & van den Maagdenberg, A. M. J. M., 16 Apr 2019, In : Neurology. 92, 16, p. E1899-E1911 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Macrovasculature and Microvasculature at the Crossroads Between Type 2 Diabetes Mellitus and Hypertension

Climie, R. E., van Sloten, T. T., Bruno, R-M., Taddei, S., Empana, J-P., Stehouwer, C. D. A., Sharman, J. E., Boutouyrie, P. & Laurent, S., Jun 2019, In : Hypertension. 73, 6, p. 1138-1149 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Porcu, E., Rueger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Fave, M-J., Franke, L., Frayling, T. & 30 others, Gharib, S. A., Gibson, G., Heijmans, B. T., Hemani, G., Jansen, R., Kahonen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Kovacs, P., Krohn, K., Kronberg-Guzman, J., Kukushkina, V., Lee, B., Lehtimaki, T., Loeffler, M., Marigorta, U. M., Mei, H., Milani, L., Montgomery, G. W., Mueler-Nurasyid, M., Nauck, M., Stehouwer, C. D. A., Isaacs, A., Schalkwijk, C. G., Stehouwer, C. D. A., van der Kallen, C. J. H. & van Greevenbroek, M. M. J., 24 Jul 2019, In : Nature Communications. 10, 12 p., 3300.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease

Hanssen, N. M. J., Stehouwer, C. D. A. & Schalkwijk, C. G., Jan 2019, In : Current Opinion in Nephrology and Hypertension. 28, 1, p. 26-33 8 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content

Simons, N., Debray, F-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D. & Brouwers, M. C. G. J., Nov 2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 11, p. 5053-5061 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Skewed X-inactivation is common in the general female population

Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H. H. M., White, S. J., Santen, G. W. E., Lopes, S. M. C. D. S., Heijmans, B. T., van Meurs, J., Jansen, R., Franke, L., Kielbasa, S. M., den Dunnen, J. T., 't Hoen, P. A. C., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Van Greevenbroek, M. M. J. & 30 others, Da Stehouwer, C., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Slagboom, P. E., Beekman, M., Deelen, J., van Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., Isaacs, A., van Dijk, F., Li, M., Isaacs, A., Cox, D. R., Li, Y., Chen, R., Li, N., Wang, J. & van Ommen, G. J., Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 455-465 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans

van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., Astrup, A., Valsesia, A., Langin, D., van der Kallen, C. J. H., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., Goossens, G. H., Arts, I. C. W., Jocken, J. W. E., Evelo, C. T. & Blaak, E. E., Dec 2019, In : Diabetes. 68, 12, p. 2247-2258 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Association Between β-Blocker Use and Cardiorespiratory Fitness: The Maastricht Study

Nielen, J. T. H., de Vries, F., van der Velde, J. H. P. M., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Schram, M., Stehouwer, C. D. A., Boonen, A., Koster, A. & van den Bemt, B. J. F., 1 Jan 2019, In : Journal of Cardiovascular Pharmacology and Therapeutics. 24, 1, p. 37-45 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Maastricht FFQ: Development and validation of a comprehensive food frequency questionnaire for the Maastricht study

van Dongen, M. C. J. M., Wijckmans-Duysens, N. E. G., den Biggelaar, L. J. C. J., Ocke, M. C., Meijboom, S., Brants, H. A. M., de Vries, J. H. M., Feskens, E. J. M., Bueno-de-Mesquita, H. B., Geelen, A., Stehouwer, C. D. A., Dagnelie, P. C. & Eussen, S. J. P. M., Jun 2019, In : Nutrition. 62, p. 39-46 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study

Tran-Duy, A., Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F. & de Boer, A., Feb 2019, In : Journal of Internal Medicine. 285, 2, p. 205-214 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Abdominal subcutaneous adipose tissue gene expression in relation to tissue-specific insulin resistance in human obesity

Oct 2018, In : Diabetologia. 61, p. S110-S110 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans

Verboven, K., Wouters, K., Gaens, K., Hansen, D., Bijnen, M., Wetzels, S., Stehouwer, C. D., Goossens, G. H., Schalkwijk, C. G., Blaak, E. E. & Jocken, J. W., 16 Mar 2018, In : Scientific Reports. 8, 8 p., 4677.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G. & Wouters, K., Jul 2018, In : Gut. 67, 7, p. 1317-1327 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

A gene variant near ATM affects the response to metformin and metformin plasma levels: a post hoc analysis of an RCT

Out, M., Becker, M. L., van Schaik, R. H., Lehert, P., Stehouwer, C. D. & Kooy, A., 1 Jun 2018, In : Pharmacogenomics. 19, 8, p. 715-726 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A possible role of decreased human serum albumin in the endothelial dysfunction caused by albuminuria Reply

Martens, R. J. H. & Stehouwer, C. D. A., Sep 2018, In : Journal of Hypertension. 36, 9, p. 1948-1949 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

A SNP panel for identification of DNA and RNA specimens

Yousefi, S., Abbassi-Daloii, T., Kraaijenbrink, T., Vermaat, M., Mei, H., van't Hof, P., van Iterson, M., Zhernakova, D. V., Claringbould, A., Franke, L., 't Hart, L. M., Slieker, R. C., van der Heijden, A., de Knijff, P., 't Hoen, P. A. C., Jansen, R., van Meurs, J., Heijmans, B. T., Boomsma, D. I., van Dongen, J. & 44 others, Hottenga, J-J., Slagboom, P. E., Suchiman, H. E. D., van Iterson, M., van Zwet, E. W., 't Hoen, P., Pool, R., van Greevenbroek, M., Stehouwer, C., van der Kallen, C., Schalkwijk, C., Wijmenga, C., Zhernakova, A., Tigchelaar, E. F., Beekman, M., Deelen, J., van Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Mei, H., Bot, J., Zhernakova, D. V., Van't Hof, P., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Bonder, M. J., van Dijk, F., van Galen, M., Arindrarto, W., Kielbasa, S. M., Swertz, M. A., Isaacs, A. & Franke, L., 25 Jan 2018, In : BMC Genomics. 19, 90, 12 p., 90.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association between bone metabolism regulators and arterial stiffness in type 2 diabetes patients

Sharif, S., Bots, M. L., Schalkwijk, C., Stehouwer, C. D. A., Visseren, F. L. J. & Westerink, J., Dec 2018, In : Nutrition Metabolism and Cardiovascular Diseases. 28, 12, p. 1245-1252 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Association of Cerebrospinal Fluid (CSF) Insulin with Cognitive Performance and CSF Biomarkers of Alzheimer's Disease

Geijselaers, S. L. C., Aalten, P., Ramakers, I. H. G. B., De Deyn, P. P., Heijboer, A. C., Koek, H. L., OldeRikkert, M. G. M., Papma, J. M., Reesink, F. E., Smits, L. L., Stehouwer, C. D. A., Teunissen, C. E., Verhey, F. R. J., van der Flier, W. M. & Biessels, G. J., 1 Jan 2018, In : Journal of Alzheimer's Disease. 61, 1, p. 309-320 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study

Gala, T. D. L. H., Herder, C., Rutters, F., Carstensen-Kirberg, M., Huth, C., Stehouwer, C. D. A., Nijpels, G., Schalkwijk, C., Flyvbjerg, A., Franks, P. W., Dekker, J., Meisinger, C., Koenig, W., Roden, M., Rathmann, W., Peters, A. & Thorand, B., Nov 2018, In : Diabetes-metabolism Research and Reviews. 34, 8, 9 p., 3063.

Research output: Contribution to journalArticleAcademicpeer-review

Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis

Simons, P. I. H. G., Simons, N., Stehouwer, C. D. A., Schalkwijk, C. G., Schaper, N. C. & Brouwers, M. C. G. J., 23 Oct 2018, In : PLOS ONE. 13, 10, 14 p., 0206174.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Association of type 2 diabetes mellitus with self-reported knee pain and clinical knee osteoarthritis: The Maastricht Study

Nielen, J. T. H., Emans, P. J., van den Bemt, B., Dagnelie, P. C., Schram, M. T., Stehouwer, C. D. A., Schaper, N. C., Denissen, K. F. M., de Vries, F. & Boonen, A., 1 Jun 2018, In : Diabetes & Metabolism. 44, 3, p. 296-299 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Associations between advanced glycation endproducts and matrix metalloproteinases and its inhibitor in individuals with type 1 diabetes

Peeters, S. A., Engelen, L., Buijs, J., Theilade, S., Rossing, P., Schalkwijk, C. G. & Stehouwer, C. D. A., 1 Mar 2018, In : Journal of Diabetes and Its Complications. 32, 3, p. 325-329 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biomarkers of inflammation and endothelial dysfunction as predictors of pulse pressure and incident hypertension in type 1 diabetes: a 20 year life-course study in an inception cohort

Ferreira, I., Hovind, P., Schalkwijk, C. G., Parving, H-H., Stehouwer, C. D. A. & Rossing, P., 1 Jan 2018, In : Diabetologia. 61, 1, p. 231-241 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes

't Hart, L. M., Vogelzangs, N., Mook-Kanamori, D. O., Brahimaj, A., Nano, J., van der Heijden, A. A. W. A., van Dijk, K. W., Slieker, R. C., Steyerberg, E. W., Ikram, M. A., Beekman, M., Boomsma, D. I., van Duijn, C. M., Slagboom, P. E., Stehouwer, C. D. A., Schalkwijk, C. G., Arts, I. C. W., Dekker, J. M., Dehghan, A., Muka, T. & 3 others, van der Kallen, C. J. H., Nijpels, G. & van Greevenbroek, M. M. J., Dec 2018, In : Journal of Clinical Endocrinology & Metabolism. 103, 12, p. 4569-4579 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Blood Pressure Variability, Arterial Stiffness, and Arterial Remodeling: The Maastricht Study

Zhou, T. L., Henry, R. M. A., Stehouwer, C. D. A., van Sloten, T. T., Reesink, K. D. & Kroon, A. A., 1 Oct 2018, In : Hypertension. 72, 4, p. 1002-1010 9 p.

Research output: Contribution to journalArticleAcademicpeer-review