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Clemens van Blitterswijk

Prof.Dr.

20142019
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Research Output 2014 2019

2019

From fiber curls to mesh waves: a platform for the fabrication of hierarchically structured nanofibers mimicking natural tissue formation

Chen, H., Baptista, D. F., Criscenti, G., Crispim, J., Fernandes, H., van Blitterswijk, C., Truckenmueller, R. & Moroni, L., 14 Aug 2019, In : Nanoscale. 11, 30, p. 14312-14321 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Grow with the Flow: When Morphogenesis Meets Microfluidics

Samal, P., van Blitterswijk, C., Truckenmuller, R. & Giselbrecht, S., 25 Apr 2019, In : Advanced Materials. 31, 17, 17 p., 1805764.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hybrid Polyester-Hydrogel Electrospun Scaffolds for Tissue Engineering Applications

de Pinho, A. R. G., Odila, I., Leferink, A., van Blitterswijk, C., Camarero-Espinosa, S. & Moroni, L., 25 Sep 2019, In : Frontiers in bioengineering and biotechnology. 7, p. 1-13 13 p., 231.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Overlooked? Underestimated? Effects of Substrate Curvature on Cell Behavior

Baptista, D., Teixeira, L., van Blitterswijk, C., Giselbrecht, S. & Truckenmuller, R., Aug 2019, In : Trends in Biotechnology. 37, 8, p. 838-854 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

Rademakers, T., Horvath, J. M., van Blitterswijk, C. A. & LaPointe, V. L. S., Oct 2019, In : Journal of Tissue Engineering and Regenerative Medicine. 13, 10, p. 1815-1829 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2018

An antibody based approach for multi-coloring osteogenic and chondrogenic proteins in tissue engineered constructs

Leferink, A. M., Reis, D. S., van Blitterswijk, C. A. & Moroni, L., 1 Jul 2018, In : Biomedical Materials. 13, 4, 9 p., 044102.

Research output: Contribution to journalArticleAcademicpeer-review

Blastocyst-like structures generated solely from stem cells

Rivron, N. C., Frias-Aldeguer, J., Vrij, E. J., Boisset, J-C., Korving, J., Vivie, J., Truckenmuller, R. K., van Oudenaarden, A., van Blitterswijk, C. A. & Geijsen, N., 3 May 2018, In : Nature. 557, 7703, p. 106-111 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Designed Surface Topographies Control ICAM-1 Expression in Tonsil-Derived Human Stromal Cells

Vasilevich, A. S., Mourcin, F., Mentink, A., Hulshof, F., Beijer, N., Zhao, Y., Levers, M., Papenburg, B., Singh, S., Carpenter, A. E., Stamatialis, D., van Blitterswijk, C., Tarte, K. & de Boer, J., 28 Jun 2018, In : Frontiers in bioengineering and biotechnology. 6, p. 1-14 14 p., 87.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Ectopic bone formation by aggregated mesenchymal stem cells from bone marrow and adipose tissue: A comparative study

Fennema, E. M., Tchang, L. A. H., Yuan, H., van Blitterswijk, C. A., Martin, I., Scherberich, A. & de Boer, J., 1 Jan 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 1, p. E150-E158 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Enhancement of synthesis of extracellular matrix proteins on retinoic acid loaded electrospun scaffolds

Damanik, F. F. R., van Blitterswijk, C., Rotmans, J. & Moroni, L., 28 Oct 2018, In : Journal of Materials Chemistry. B, Materials for Biology and Medicine. 6, 40, p. 6468-6480 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Geometric constraints of endothelial cell migration on electrospun fibres

Ahmed, M., Ramos, T., Wieringa, P., van Blitterswijk, C., de Boer, J. & Moroni, L., 23 Apr 2018, In : Scientific Reports. 8, p. 1-10 10 p., 6386.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

New insights into the effects of biomaterial chemistry and topography on the morphology of kidney epithelial cells

Hulshof, F., Schophuizen, C., Mihajlovic, M., van Blitterswijk, C., Masereeuw, R., de Boer, J. & Stamatialis, D., Feb 2018, In : Journal of Tissue Engineering and Regenerative Medicine. 12, 2, p. E817-E827 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Soft-molecular imprinted electrospun scaffolds to mimic specific biological tissues

Criscenti, G., De Maria, C., Longoni, A., van Blitterswijk, C. A., Fernandes, H. A. M., Vozzi, G. & Moroni, L., Oct 2018, In : Biofabrication. 10, 4, 9 p., 045005.

Research output: Contribution to journalArticleAcademicpeer-review

The Components of Bone and What They Can Teach Us about Regeneration

Le, B. Q., Nurcombe, V., Cool, S. M., van Blitterswijk, C. A., de Boer, J. & LaPointe, V. L. S., Jan 2018, In : Materials. 11, 1, 16 p., 14.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Viscoelastic Oxidized Alginates with Reversible Imine Type Crosslinks: Self-Healing, Injectable, and Bioprintable Hydrogels

Hafeez, S., Ooi, H. W., Morgan, F. L. C., Mota, C., Dettin, M., Van Blitterswijk, C., Moroni, L. & Baker, M. B., 21 Nov 2018, In : Gels (Basel, Switzerland). 4, 4, p. 1-19 19 p., 85.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

1.14 Calcium Phosphates and Bone Induction ☆

Yuan, H., Barbieri, D., Luo, X., Van Blitterswijk, C. A. & De Bruijn, J. D., 2017, Comprehensive Biomaterials II. Elsevier, p. 333-349 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

3D screening device for the evaluation of cell response to different electrospun microtopographies

Criscenti, G., Vasilevich, A., Longoni, A., De Maria, C., van Blitterswijk, C. A., Truckenmuller, R., Vozzi, G., De Boer, J. & Moroni, L., Jun 2017, In : Acta Biomaterialia. 55, p. 310-322 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

An Approach to In Vitro Manufacturing of Hypertrophic Cartilage Matrix for Bone Repair

Quang Le, B., Van Blitterswijk, C. & De Boer, J., 20 Apr 2017, In : Bioengineering. 4, 2, 18 p., 35.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Calcium phosphates and silicon: exploring methods of incorporation

Rodrigues, A. I., Reis, R. L., van Blitterswijk, C. A., Leonor, I. B. & Habibović, P., 2017, In : Biomaterials research. 21, p. 6

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

CELL AGGREGATION ENHANCES BONE FORMATION BY HUMAN MESENCHYMAL STROMAL CELLS

Chatterjea, A., LaPointe, V. L. S., Barradas, A., Garritsen, H., Yuan, H., Renard, A., van Blitterswijk, C. A. & de Boer, J., 2017, In : European Cells & Materials. 33, p. 121-129 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cell-instructive high-resolution micropatterned polylactic acid surfaces

Barata, D., Dias, P., Wieringa, P., van Blitterswijk, C. & Habibovic, P., Sep 2017, In : Biofabrication. 9, 3, 17 p., 035004.

Research output: Contribution to journalArticleAcademicpeer-review

Cells responding to surface structure of calcium phosphate ceramics for bone regeneration

Zhang, J., Sun, L., Luo, X., Barbieri, D., de Bruijn, J. D., van Blitterswijk, C. A., Moroni, L. & Yuan, H., Nov 2017, In : Journal of Tissue Engineering and Regenerative Medicine. 11, 11, p. 3273-3283 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Covalent Binding of Bone Morphogenetic Protein-2 and Transforming Growth Factor-β3 to 3D Plotted Scaffolds for Osteochondral Tissue Regeneration

Di Luca, A., Klein-Gunnewiek, M., Vancso, J. G., van Blitterswijk, C. A., Benetti, E. M. & Moroni, L., Dec 2017, In : Biotechnology Journal. 12, 12, 9 p., 1700072.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Development of a microfluidic platform integrating high-resolution microstructured biomaterials to study cell-material interactions

Barata, D., Provaggi, E., van Blitterswijk, C. & Habibovic, P., 7 Dec 2017, In : Lab on A Chip. 17, 23, p. 4134-4147 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Development of a shear stress-free microfluidic gradient generator capable of quantitatively analyzing single-cell morphology

Barata, D., Spennati, G., Correia, C., Ribeiro, N., Harink, B., van Blitterswijk, C., Habibovic, P. & van Rijt, S., Dec 2017, In : Biomedical Microdevices. 19, 4, 10 p., 81.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Engineering Niches for Bone Tissue Regeneration

Malhotra, A., Van Blitterswijk, C. & Habibovic, P., 6 Apr 2017, Biology and Engineering of Stem Cell Niches. 1 ed. Elsevier, p. 499-516 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Hydrogels that listen to cells: a review of cell-responsive strategies in biomaterial design for tissue regeneration

Ooi, H. W., Hafeez, S., van Blitterswijk, C. A., Moroni, L. & Baker, M. B., 1 Nov 2017, In : Materials Horizons. 4, 6, p. 1020-1040 21 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Influence of Additive Manufactured Scaffold Architecture on the Distribution of Surface Strains and Fluid Flow Shear Stresses and Expected Osteochondral Cell Differentiation

Hendrikson, W. J., Deegan, A. J., Yang, Y., van Blitterswijk, C. A., Verdonschot, N., Moroni, L. & Rouwkema, J., 10 Feb 2017, In : Frontiers in bioengineering and biotechnology. 5, 11 p., 6.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Linking the Transcriptional Landscape of Bone Induction to Biomaterial Design Parameters

Groen, N., Yuan, H., Hebels, D. G. A. J., Kocer, G., Mbuyi, F., LaPointe, V., Truckenmuller, R., van Blitterswijk, C. A., Habibovic, P. & de Boer, J., 14 Mar 2017, In : Advanced Materials. 29, 10, 14 p., 1603259.

Research output: Contribution to journalArticleAcademicpeer-review

Micro-fabricated scaffolds lead to efficient remission of diabetes in mice

Buitinga, M., Assen, F., Hanegraaf, M., Wieringa, P., Hilderink, J., Moroni, L., Truckenmüller, R., van Blitterswijk, C., Roemer, G-W., Carlotti, F., de Koning, E., Karperien, M. & van Apeldoorn, A., Aug 2017, In : Biomaterials. 135, p. 10-22 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Micro-Topographies Promote Late Chondrogenic Differentiation Markers in the ATDC5 Cell Line

Le, B. Q., Vasilevich, A., Vermeulen, S., Hulshof, F., Stamatialis, D. F., van Blitterswijk, C. A. & de Boer, J., May 2017, In : Journal of Tissue Science & Engineering. 23, 9-10, p. 458-469 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mining for osteogenic surface topographies: In silico design to in vivo osseo-integration

Hulshof, F. F. B., Papenburg, B., Vasilevich, A., Hulsman, M., Zhao, Y., Levers, M., Fekete, N., de Boer, M., Yuan, H., Singh, S., Beijer, N., Bray, M-A., Reinders, M., Carpenter, A. E., van Blitterswijk, C., Stamatialis, D., de Boer, J. & Logan, D. J., Aug 2017, In : Biomaterials. 137, p. 49-60 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

NanoTopoChip: High-throughput nanotopographical cell instruction

Hulshof, F. F. B., Zhao, Y., Vasilevich, A., Beijer, N. R. M., de Boer, M., Papenburg, B. J., van Blitterswijk, C., Stamatialis, D. & de Boer, J., 15 Oct 2017, In : Acta Biomaterialia. 62, p. 188-198 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tailorable Surface Morphology of 3D Scaffolds by Combining Additive Manufacturing with Thermally Induced Phase Separation

Di Luca, A., de Wijn, J. R., van Blitterswijk, C. A., Camarero-Espinosa, S. & Moroni, L., Aug 2017, In : Macromolecular Rapid Communications. 38, 16, 5 p., 1700186.

Research output: Contribution to journalArticleAcademicpeer-review

Tailoring surface nanoroughness of electrospun scaffolds for skeletal tissue engineering

Chen, H., Huang, X., Zhang, M., Damanik, F., Baker, M. B., Leferink, A., Yuan, H., Truckenmuller, R., van Blitterswijk, C. & Moroni, L., 1 Sep 2017, In : Acta Biomaterialia. 59, p. 82-93 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Use of Finite Element Analyses to Design and Fabricate Three-Dimensional Scaffolds for Skeletal Tissue Engineering

Hendrikson, W. J., van Blitterswijk, C. A., Rouwkema, J. & Moroni, L., May 2017, In : Frontiers in bioengineering and biotechnology. 5, 13 p., 30.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Topography of calcium phosphate ceramics regulates primary cilia length and TGF receptor recruitment associated with osteogenesis

Zhang, J., Dalbay, M. T., Luo, X., Vrij, E., Barbieri, D., Moroni, L., de Bruijn, J. D., van Blitterswijk, C. A., Chapple, J. P., Knight, M. M. & Yuan, H., 15 Jul 2017, In : Acta Biomaterialia. 57, p. 487-497 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Towards 4D printed scaffolds for tissue engineering: exploiting 3D shape memory polymers to deliver time-controlled stimulus on cultured cells

Hendrikson, W. J., Rouwkema, J., Clementi, F., van Blitterswijk, C. A., Fare, S. & Moroni, L., Sep 2017, In : Biofabrication. 9, 3, 7 p., 031001.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016
7 Citations (Scopus)

3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates

Vrij, E. J., Espinoza, S., Heilig, M., Kolew, A., Schneider, M., van Blitterswijk, C. A., Truckenmuller, R. K. & Rivron, N. C., 2016, In : Lab on A Chip. 16, 4, p. 734-742

Research output: Contribution to journalArticleAcademicpeer-review

Adhesion and proliferation of cells and bacteria on microchip with different surfaces microstructures

Zhou, Y., Xiao, Y., Qiu, Y., Yuan, H., van Blitterswijk, C. A., Zhou, X., Xu, X. & Bao, C., Oct 2016, In : Biomedizinische Technik. 61, 5, p. 475-482

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Biological and Tribological Assessment of Poly(Ethylene Oxide Terephthalate)/Poly(Butylene Terephthalate), Polycaprolactone, and Poly (L\DL) Lactic Acid Plotted Scaffolds for Skeletal Tissue Regeneration

Hendrikson, W. J., Zeng, X., Rouwkema, J., van Blitterswijk, C. A., van der Heide, E. & Moroni, L., 21 Jan 2016, In : Advanced Healthcare Materials. 5, 2, p. 232-243

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Chondrocytes Cocultured with Stromal Vascular Fraction of Adipose Tissue Present More Intense Chondrogenic Characteristics Than with Adipose Stem Cells

Wu, L., Prins, H-J., Leijten, J., Helder, M. N., Evseenko, D., Moroni, L., van Blitterswijk, C. A., Lin, Y. & Karperien, M., 1 Feb 2016, In : TISSUE ENGINEERING PART A. 22, 3-4, p. 336-348

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site

Buitinga, M., Portalska, K. J., Cornelissen, D-J., Plass, J., Hanegraaf, M., Carlotti, F., de Koning, E., Engelse, M., van Blitterswijk, C., Karperien, M., van Apeldoorn, A. & de Boer, J., 1 Feb 2016, In : TISSUE ENGINEERING PART A. 22, 3-4, p. 375-385

Research output: Contribution to journalArticleAcademicpeer-review

Collagen modules for in situ delivery of mesenchymal stromal cell-derived endothelial cells for improved angiogenesis

Portalska, K. J., Chamberlain, M. D., Khor, C-C., van Blitterswijk, C., Sefton, M. V. & de Boer, J., May 2016, In : Journal of Tissue Engineering and Regenerative Medicine. 10, 5, p. 363-373

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Combinatorial incorporation of fluoride and cobalt ions into calcium phosphates to stimulate osteogenesis and angiogenesis

Birgani, Z. T., Gharraee, N., Malhotra, A., van Blitterswijk, C. A. & Habibovic, P., Feb 2016, In : Biomedical Materials. 11, 1, 015020.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Development and evaluation of in vivo tissue engineered blood vessels in a porcine model

Rothuizen, T. C., Damanik, F. F. R., Lavrijsen, T., Visser, M. J. T., Hamming, J. F., Lalai, R. A., Duijs, J. M. G. J., van Zonneveld, A. J., Hoefer, I. E., van Blitterswijk, C. A., Rabelink, T. J., Moroni, L. & Rotmans, J. I., Jan 2016, In : Biomaterials. 75, p. 82-90

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Development of Highly Functional Biomaterials by Decoupling and Recombining Material Properties

Danoux, C., Sun, L., Kocer, G., Birgani, Z. T., Barata, D., Barralet, J., van Blitterswijk, C., Truckenmuller, R. & Habibovic, P., 2 Mar 2016, In : Advanced Materials. 28, 9, p. 1803-1808

Research output: Contribution to journalArticleAcademicpeer-review