Chiel de Theije

2024

SARS-CoV-2 cellular and humoral responses in vaccine-naive individuals during the first two waves of COVID-19 infections in the southern region of The Netherlands: a cross-sectional population-based study

Hanssen, D. A. T., Arts, K., Nix, W. H. V., Sweelssen, N. N. B., Welbers, T. T. J., de Theije, C., Wieten, L., Pagen, D. M. E., Brinkhues, S., Penders, J., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., Savelkoul, P. H. M. & van Loo, I. H. M., Jun 2024, In: Microbiology spectrum. 12, 6, 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

2020

Biobanking in Molecular Biomarker Research for the Early Detection of Cancer

Lommen, K., Odeh, S., de Theije, C. C. & Smits, K. M., Apr 2020, In: Cancers. 12, 4, 11 p., 776.

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Open Access

Recovery of muscle mass and muscle oxidative phenotype following disuse does not require GSK-3 inactivation

Theeuwes, W. F., Pansters, N. A. M., Gosker, H. R., Schols, A. M. W. J., Verhees, K. J. P., de Theije, C. C., van Gorp, R. H. P., Kelders, M. C. J. M., Ronda, O., Haegens, A., Remels, A. H. & Langen, R. C. J., 1 Jun 2020, In: Biochimica et Biophysica Acta-Molecular Basis of Disease. 1866, 6, 14 p., 165740.

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Open Access

Resveratrol and metabolic health in COPD: A proof-of-concept randomized controlled trial

Beijers, R. J. H. C. G., Gosker, H. R., Sanders, K. J. C., de Theije, C., Kelders, M., Clarke, G., Cryan, J. F., van den Borst, B. & Schols, A. M. W. J., Oct 2020, In: Clinical Nutrition. 39, 10, p. 2989-2997 9 p.

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2019

Impaired Skeletal Muscle Kynurenine Metabolism in Patients with Chronic Obstructive Pulmonary Disease

Gosker, H. R., Clarke, G., de Theije, C. C., Cryan, J. E. & Schols, A. M. W. J., Jul 2019, In: Journal of Clinical Medicine. 8, 7, 7 p., 915.

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Open Access

Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation

Leermakers, P. A., Kneppers, A. E. M., Schols, A. M. W. J., Kelders, M. C. J. M., de Theije, C. C., Verdijk, L. B., van Loon, L. J. C., Langen, R. C. J. & Gosker, H. R., Dec 2019, In: Muscle & Nerve. 60, 6, p. 769-778 10 p.

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Open Access

2018

Altered protein turnover signaling and myogenesis during impaired recovery of inflammation-induced muscle atrophy in emphysematous mice

Ceelen, J. J. M., Schols, A. M. W. J., Kneppers, A. E. M., Rosenbrand, R. P. H. A., Drozdz, M. M., van Hoof, S. J., de Theije, C. C., Kelders, M. C. J. M., Verhaegen, F. & Langen, R. C. J., 17 Jul 2018, In: Scientific Reports. 8, 1, 12 p., 10761.

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Open Access

A novel in vitro model for the assessment of postnatal myonuclear accretion

Kneppers, A., Verdijk, L., de Theije, C., Corten, M., Gielen, E., van Loon, L., Schols, A. & Langen, R., 14 Feb 2018, In: Skeletal Muscle. 8, 1, 13 p., 4.

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Open Access

Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice

Theije, C. C., Schols, A. M. W. J., Lamers, W. H., Ceelen, J. J. M., van Gorp, R. H., Hermans, J. J. R., Kohler, S. E. & Langen, R. C. J., 1 Jan 2018, In: Endocrinology. 159, 1, p. 519-534 16 p.

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Hypoxia impairs adaptation of skeletal muscle protein turnover- and AMPK signaling during fasting-induced muscle atrophy

de Theije, C. C., Schols, A. M. W. J., Lamers, W. H., Neumann, D., Kohler, S. E. & Langen, R. C. J., 13 Sept 2018, In: PLOS ONE. 13, 9, 18 p., 0203630.

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Open Access

Molecular signalling towards mitochondrial breakdown is enhanced in skeletal muscle of patients with chronic obstructive pulmonary disease (COPD)

Leermakers, P. A., Schols, A. M. W. J., Kneppers, A. E. M., Kelders, M. C. J. M., de Theije, C. C., Lainscak, M. & Gosker, H. R., 9 Oct 2018, In: Scientific Reports. 8, 1, 13 p., 15007.

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Open Access

NF-kappa B-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis

Remels, A. H. V., Derks, W. J. A., Cillero-Pastor, B., Verhees, K. J. P., Kelders, M. C., Heggermont, W., Carai, P., Summer, G., Ellis, S. R., de Theije, C. C., Heeren, R. M. A., Heymans, S., Papageorgiou, A. P. & van Bilsen, M., Aug 2018, In: Biochimica et Biophysica Acta-Molecular Basis of Disease. 1864, 8, p. 2579-2589 11 p.

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Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation

Ceelen, J. J. M., Schols, A. M. W. J., Thielen, N. G. M., Haegens, A., Gray, D. A., Kelders, M. C. J. M., de Theije, C. C. & Langen, R. C. J., 2 May 2018, In: Respiratory Research. 19, 1, 11 p., 80.

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Open Access

2017

Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammation

Ceelen, J. J. M., Schols, A. M. W. J., van Hoof, S. J., de Theije, C. C., Verhaegen, F. & Langen, R. C. J., 2 May 2017, In: Respiratory Research. 18, 1, 10 p., 75.

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Open Access

Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia

Kneppers, A. E. M., Langen, R. C. J., Gosker, H. R., Verdijk, L. B., Lipovec, N. C., Leermakers, P. A., Kelders, M. C. J. M., de Theije, C. C., Omersa, D., Lainscak, M. & Schols, A. M. W. J., 1 Jul 2017, In: Journal of the American Medical Directors Association. 18, 7, p. 637.e1-637.e11 11 p.

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2016

Alterations in Skeletal Muscle Oxidative Phenotype in Mice Exposed to 3 Weeks of Normobaric Hypoxia

Slot, I. G. M., Schols, A. M. W. J., De Theije, C. C., Snepvangers, F. J. M. & Gosker, H. R., Feb 2016, In: Journal of Cellular Physiology. 231, 2, p. 377-392

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2015

Differential sensitivity of oxidative and glycolytic muscles to hypoxia-induced muscle atrophy

de Theije, C. C., Langen, R. C., Lamers, W. H., Gosker, H. R., Schols, A. M. & Koehler, S. E., 15 Jan 2015, In: Journal of Applied Physiology. 118, 2, p. 200-211 12 p.

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Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

Gopal, P., Gosker, H. R., de Theije, C. C., Eurlings, I., Sell, D. R., Monnier, V. M. & Reynaert, N. L., May 2015, In: Biochimica et Biophysica Acta-Molecular Basis of Disease. 1852, 5, p. 992-1000 9 p.

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Muscle-specific GSK-3beta ablation accelerates regeneration of disuse-atrophied skeletal muscle

Pansters, N. A. M., Schols, A. M., Verhees, K. J., de Theije, C. C., Snepvangers, F., Kelders, M. C. J. M., Ubags, N. D. J., Haegens, A. & Langen, R. C., 1 Jan 2015, In: Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 1852, 3, p. 490-506

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Open Access

2014

Cigarette Smoke Extract Induces a Phenotypic Shift in Epithelial Cells; Involvement of HIF1α in Mesenchymal Transition

Eurlings, I. M. J., Reynaert, N. L., van den Beucken, T., Gosker, H. R., de Theije, C. C., Verhamme, F. M., Bracke, K. R., Wouters, E. F. M. & Dentener, M. A., 16 Oct 2014, In: PLOS ONE. 9, 10, 11 p., e107757.

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Open Access

Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice

Poels, E. M., Bitsch, N., Slenter, J. M., Kooi, M. E., de Theije, C. C., De Windt, L. J., van Empel, V. P. & da Costa Martins, P. A., 15 Apr 2014, In: PLOS ONE. 9, 4, 7 p., 92983.

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Open Access

2013

Ablation of Arg1 in hematopoietic cells improves respiratory function of lung parenchyma, but not that of larger airways or inflammation in asthmatic mice

Cloots, R. H. E., Sankaranarayanan, S., de Theije, C. C., Poynter, M. E., Terwindt, E., van Dijk, P. J., Hakvoort, T. B., Lamers, W. H. & Köhler, S. E., 1 Jan 2013, In: American Journal of Physiology-Lung Cellular and Molecular Physiology. 305, 5, p. L364-376

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Characterization of the inflammatory and metabolic profile of adipose tissue in a mouse model of chronic hypoxia.

van den Borst, B., Schols, A. M. W. J., de Theije, C. C., Boots, A. W., Köhler, S. E., Goossens, G. H. & Gosker, H. R., Jun 2013, In: Journal of Applied Physiology. 114, 11, p. 1619-1628 10 p.

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Distinct responses of protein turnover regulatory pathways in hypoxia- and semistarvation-induced muscle atrophy.

de Theije, C. C., Langen, R. C. J., Lamers, W. H., Schols, A. M. W. J. & Köhler, S. E., Jul 2013, In: American Journal of Physiology-Lung Cellular and Molecular Physiology. 305, 1, p. L82-L91 10 p.

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Hepatic adaptation compensates inactivation of intestinal arginine biosynthesis in suckling mice

Marion, V., Sankaranarayanan, S., de Theije, C., van Dijk, P. J., Hakvoort, T. B., Lamers, W. H. & Köhler, E. S., 13 Jun 2013, In: PLOS ONE. 8, 6, 12 p., 67021.

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Open Access

Nuclear transcription factor κ B activation and protein turnover adaptations in skeletal muscle of patients with progressive stages of lung cancer cachexia.

Op den Kamp, C. M. H., Langen, R. C. J., Snepvangers, F. J., de Theije, C. C., Schellekens, J. M., Laugs, F., Dingemans, A. M. & Schols, A. M. W. J., Sept 2013, In: American Journal of Clinical Nutrition. 98, 3, p. 738-748 11 p.

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Open Access

Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy

Verhees, K. J., Pansters, N. A. M., Baarsma, H. A., Remels, A. H., Haegens, A., de Theije, G. C., Schols, A. M., Gosens, R. & Langen, R. C., 1 Jan 2013, In: Respiratory Research. 14, 1, p. 117

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Open Access

2011

Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2

Marion, V., Sankaranarayanan, S., de Theije, C. C., van Dijk, P. J., Lindsey, P. J., Lamers, M. C., Harding, H. P., Ron, D., Lamers, W. H. & Köhler, S. E., 18 Mar 2011, In: Journal of Biological Chemistry. 286, 11, p. 8866-8874 9 p.

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Open Access

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Hypoxia and muscle maintenance regulation: implications for chronic respiratory disease

de Theije, C., Costes, F., Langen, R. C., Pison, C. & Gosker, H. R., Nov 2011, In: Current Opinion in Clinical Nutrition and Metabolic Care. 14, 6, p. 548-553 6 p.

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2010

Glutamine synthetase in muscle is required for glutamine production during fasting and extrahepatic ammonia detoxification.

He, Y., Hakvoort, T. B., Koehler, S. E., Vermeulen, J. L., de Waart, D. R., de Theije, C. C., Ten Have, G. A., van Eijk, H. M., Kunne, C., Labruyere, W. T., Houten, S. M., Sokolovic, M., Ruijter, J. M., Deutz, N. E. & Lamers, W. H., 26 Mar 2010, In: Journal of Biological Chemistry. 285, 13, p. 9516-9524 9 p.

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Open Access

2006

Subcutaneous and intrahepatic growth of human hepatoblastoma in immunodeficient mice

Schnater, M. J., Bruder, E., Bertschin, S., Woodtli, T., de Theije, C. C., Pietsch, T., Aronson, D. C., von Schweinitz, D., Lamers, W. H. & Kohler, S. E., 1 Jan 2006, In: Journal of Hepatology. 45, 3, p. 377-386

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Chiel de Theije

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