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Chiel de Theije

Dr.

20062019
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Research Output 2006 2019

2019

Impaired Skeletal Muscle Kynurenine Metabolism in Patients with Chronic Obstructive Pulmonary Disease

Gosker, H. R., Clarke, G., de Theije, C. C., Cryan, J. E. & Schols, A. M. W. J., Jul 2019, In : Journal of Clinical Medicine. 8, 7, 7 p., 915.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2018

Altered protein turnover signaling and myogenesis during impaired recovery of inflammation-induced muscle atrophy in emphysematous mice

Ceelen, J. J. M., Schols, A. M. W. J., Kneppers, A. E. M., Rosenbrand, R. P. H. A., Drozdz, M. M., van Hoof, S. J., de Theije, C. C., Kelders, M. C. J. M., Verhaegen, F. & Langen, R. C. J., 17 Jul 2018, In : Scientific Reports. 8, 12 p., 10761.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A novel in vitro model for the assessment of postnatal myonuclear accretion

Kneppers, A., Verdijk, L., de Theije, C., Corten, M., Gielen, E., van Loon, L., Schols, A. & Langen, R., 14 Feb 2018, In : Skeletal Muscle. 8, 13 p., 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice

Theije, C. C., Schols, A. M. W. J., Lamers, W. H., Ceelen, J. J. M., van Gorp, R. H., Hermans, J. J. R., Kohler, S. E. & Langen, R. C. J., 1 Jan 2018, In : Endocrinology. 159, 1, p. 519-534 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hypoxia impairs adaptation of skeletal muscle protein turnover- and AMPK signaling during fasting-induced muscle atrophy

de Theije, C. C., Schols, A. M. W. J., Lamers, W. H., Neumann, D., Kohler, S. E. & Langen, R. C. J., 13 Sep 2018, In : PLOS ONE. 13, 9, 18 p., 0203630.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

NF-kappa B-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis

Remels, A. H. V., Derks, W. J. A., Cillero-Pastor, B., Verhees, K. J. P., Kelders, M. C., Heggermont, W., Carai, P., Summer, G., Ellis, S. R., de Theije, C. C., Heeren, R. M. A., Heymans, S., Papageorgiou, A. P. & van Bilsen, M., Aug 2018, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1864, 8, p. 2579-2589 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation

Ceelen, J. J. M., Schols, A. M. W. J., Thielen, N. G. M., Haegens, A., Gray, D. A., Kelders, M. C. J. M., de Theije, C. C. & Langen, R. C. J., 2 May 2018, In : Respiratory Research. 19, 11 p., 80.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammation

Ceelen, J. J. M., Schols, A. M. W. J., van Hoof, S. J., de Theije, C. C., Verhaegen, F. & Langen, R. C. J., 2 May 2017, In : Respiratory Research. 18, 10 p., 75.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
46 Downloads (Pure)

Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia

Kneppers, A. E. M., Langen, R. C. J., Gosker, H. R., Verdijk, L. B., Lipovec, N. C., Leermakers, P. A., Kelders, M. C. J. M., de Theije, C. C., Omersa, D., Lainscak, M. & Schols, A. M. W. J., 1 Jul 2017, In : Journal of the American Medical Directors Association. 18, 7, p. 637.e1-637.e11 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2016
2 Citations (Scopus)
22 Downloads (Pure)

Alterations in Skeletal Muscle Oxidative Phenotype in Mice Exposed to 3 Weeks of Normobaric Hypoxia

Slot, I. G. M., Schols, A. M. W. J., De Theije, C. C., Snepvangers, F. J. M. & Gosker, H. R., Feb 2016, In : Journal of Cellular Physiology. 231, 2, p. 377-392

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
2015
13 Citations (Scopus)

Differential sensitivity of oxidative and glycolytic muscles to hypoxia-induced muscle atrophy

de Theije, C. C., Langen, R. C., Lamers, W. H., Gosker, H. R., Schols, A. M. & Koehler, S. E., 15 Jan 2015, In : Journal of Applied Physiology. 118, 2, p. 200-211 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice

Gopal, P., Gosker, H. R., de Theije, C. C., Eurlings, I., Sell, D. R., Monnier, V. M. & Reynaert, N. L., May 2015, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1852, 5, p. 992-1000 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Muscle-specific GSK-3beta ablation accelerates regeneration of disuse-atrophied skeletal muscle

Pansters, N. A. M., Schols, A. M., Verhees, K. J., de Theije, C. C., Snepvangers, F., Kelders, M. C. J. M., Ubags, N. D. J., Haegens, A. & Langen, R. C., 1 Jan 2015, In : Biochimica et Biophysica Acta. 1852, 3, p. 490-506

Research output: Contribution to journalArticleAcademicpeer-review

2014
12 Citations (Scopus)

Cigarette Smoke Extract Induces a Phenotypic Shift in Epithelial Cells; Involvement of HIF1α in Mesenchymal Transition

Eurlings, I. M. J., Reynaert, N. L., van den Beucken, T., Gosker, H. R., de Theije, C. C., Verhamme, F. M., Bracke, K. R., Wouters, E. F. M. & Dentener, M. A., 16 Oct 2014, In : PLOS ONE. 9, 10, 11 p., e107757.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice

Poels, E. M., Bitsch, N., Slenter, J. M., Kooi, M. E., de Theije, C. C., De Windt, L. J., van Empel, V. P. & da Costa Martins, P. A., 15 Apr 2014, In : PLOS ONE. 9, 4, 7 p., 92983.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2013
6 Citations (Scopus)

Ablation of Arg1 in hematopoietic cells improves respiratory function of lung parenchyma, but not that of larger airways or inflammation in asthmatic mice

Cloots, R. H. E., Sankaranarayanan, S., de Theije, C. C., Poynter, M. E., Terwindt, E., van Dijk, P. J., Hakvoort, T. B., Lamers, W. H. & Köhler, S. E., 1 Jan 2013, In : American Journal of Physiology-Lung Cellular and Molecular Physiology. 305, 5, p. L364-376

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)

Characterization of the inflammatory and metabolic profile of adipose tissue in a mouse model of chronic hypoxia.

van den Borst, B., Schols, A. M. W. J., de Theije, C. C., Boots, A. W., Köhler, S. E., Goossens, G. H. & Gosker, H. R., Jun 2013, In : Journal of Applied Physiology. 114, 11, p. 1619-1628 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)
2 Citations (Scopus)

Hepatic adaptation compensates inactivation of intestinal arginine biosynthesis in suckling mice

Marion, V., Sankaranarayanan, S., de Theije, C., van Dijk, P. J., Hakvoort, T. B., Lamers, W. H. & Köhler, E. S., 13 Jun 2013, In : PLOS ONE. 8, 6, 12 p., 67021.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
47 Citations (Scopus)

Nuclear transcription factor κ B activation and protein turnover adaptations in skeletal muscle of patients with progressive stages of lung cancer cachexia.

Op den Kamp, C. M. H., Langen, R. C. J., Snepvangers, F. J., de Theije, C. C., Schellekens, J. M., Laugs, F., Dingemans, A. M. & Schols, A. M. W. J., Sep 2013, In : American Journal of Clinical Nutrition. 98, 3, p. 738-748 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy

Verhees, K. J., Pansters, N. A. M., Baarsma, H. A., Remels, A. H., Haegens, A., de Theije, G. C., Schols, A. M., Gosens, R. & Langen, R. C., 1 Jan 2013, In : Respiratory Research. 14, p. 117

Research output: Contribution to journalArticleAcademicpeer-review

2011
4 Citations (Scopus)

Arginine deficiency causes runting in the suckling period by selectively activating the stress kinase GCN2

Marion, V., Sankaranarayanan, S., de Theije, C. C., van Dijk, P. J., Lindsey, P. J., Lamers, M. C., Harding, H. P., Ron, D., Lamers, W. H. & Köhler, S. E., 18 Mar 2011, In : Journal of Biological Chemistry. 286, 11, p. 8866-8874 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

Hypoxia and muscle maintenance regulation: implications for chronic respiratory disease

de Theije, C., Costes, F., Langen, R. C., Pison, C. & Gosker, H. R., Nov 2011, In : Current Opinion in Clinical Nutrition and Metabolic Care. 14, 6, p. 548-553 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2010
26 Citations (Scopus)

Glutamine synthetase in muscle is required for glutamine production during fasting and extrahepatic ammonia detoxification.

He, Y., Hakvoort, T. B., Koehler, S. E., Vermeulen, J. L., de Waart, D. R., de Theije, C. C., Ten Have, G. A., van Eijk, H. M., Kunne, C., Labruyere, W. T., Houten, S. M., Sokolovic, M., Ruijter, J. M., Deutz, N. E. & Lamers, W. H., 26 Mar 2010, In : Journal of Biological Chemistry. 285, 13, p. 9516-9524 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2006
21 Citations (Scopus)

Subcutaneous and intrahepatic growth of human hepatoblastoma in immunodeficient mice

Schnater, M. J., Bruder, E., Bertschin, S., Woodtli, T., de Theije, C. C., Pietsch, T., Aronson, D. C., von Schweinitz, D., Lamers, W. H. & Kohler, S. E., 1 Jan 2006, In : Journal of Hepatology. 45, 3, p. 377-386

Research output: Contribution to journalArticleAcademicpeer-review