Blanche Schroen

Research output

Research output per year 2006 2012 2015 2017 2018 2020 2023

• 37 Article
• 6 (Systematic) Review article
• 1 Inaugural speech
• 1 Chapter

Research output per year

Research output per year

Search results

• 2021

  Genomic instability in the naturally and prematurely aged myocardium

  De Majo, F., Martens, L., Hegenbarth, J. C., Ruhle, F., Hamczyk, M. R., Nevado, R. M., Andres, V., Hilbold, E., Bar, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A. S., Stoll, M. & De Windt, L. J., 7 Sept 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 36, 8 p., e2022974118.

  Research output: Contribution to journal › Article › Academic › peer-review
• 2020

  A Year in the Life of the EU-CardioRNA COST Action: CA17129 Catalysing Transcriptomics Research in Cardiovascular Disease

  Robinson, E. L., Gomes, C. P. C., Potocnjak, I., Hellemans, J., Betsou, F., de Gonzalo-Calvo, D., Stoll, M., Yilmaz, M. B., Agg, B., Beis, D., Carmo-Fonseca, M., Enguita, F. J., Dogan, S., Tuna, B. G., Schroen, B., Ammerlaan, W., Kuster, G. M., Carpusca, I., Pedrazzini, T., Emanueli, C., & 3 othersMartelli, F., Devaux, Y. & EU-CardioRNA COST Action, Jun 2020, In: Non-coding RNA. 6, 2, 20 p., 17.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts

  De Majo, F., Hegenbarth, J-C., Ruehle, F., Baer, C., Thum, T., de Boer, M., Duncker, D. J., Schroen, B., Armand, A-S., Stoll, M. & De Windt, L. J., 18 May 2020, In: Scientific Reports. 10, 1, 14 p., 8136.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• High-Sensitivity Troponin-T and Cardiovascular Outcomes in the Community: Differences Between Women and Men

  Suthahar, N., Meems, L. M. G., van Veldhuisen, D. J., Walter, J. E., Gansevoort, R. T., Heymans, S., Schroen, B., van der Harst, P., Kootstra-Ros, J. E., van Empel, V., Mueller, C., Bakker, S. J. L. & de Boer, R. A., Jun 2020, In: Mayo Clinic Proceedings. 95, 6, p. 1158-1168 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Regulatory RNAs in Heart Failure

  Gomes, C. P. C., Schroen, B., Kuster, G. M., Robinson, E. L., Ford, K., Squire, I. B., Heymans, S., Martelli, F., Emanueli, C., Devaux, Y. & EU-CardioRNA COST Action (CA17129), 28 Jan 2020, In: Circulation. 141, 4, p. 313-328 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• tRNAs and tRNA fragments as modulators of cardiac and skeletal muscle function

  Liapi, E., van Bilsen, M., Verjans, R. & Schroen, B., Mar 2020, In: Biochimica et Biophysica Acta-Molecular Cell Research. 1867, 3, 9 p., 118465.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2019

  AntagomiR-103 and-107 Treatment Affects Cardiac Function and Metabolism

  Rech, M., Kuhn, A. R., Lumens, J., Carai, P., van Leeuwen, R., Verhesen, W., Verjans, R., Lecomte, J., Liu, Y., Luiken, J. J. F. P., Mohren, R., Cillero-Pastor, B., Heymans, S., Knoops, K., van Bilsen, M. & Schroen, B., 1 Mar 2019, In: Molecular Therapy - Nucleic Acids. 14, p. 424-437 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Functional Screening Identifies MicroRNAs as Multi-Cellular Regulators of Heart Failure

  Verjans, R., Derks, W. J. A., Korn, K., Soennichsen, B., van Leeuwen, R. E. W., Schroen, B., van Bilsen, M. & Heymans, S., 15 Apr 2019, In: Scientific Reports. 9, 15 p., 6055.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Long Noncoding RNA-Enriched Vesicles Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis

  Kenneweg, F., Bang, C., Xiao, K., Boulanger, C. M., Loyer, X., Mazlan, S., Schroen, B., Hermans-Beijnsberger, S., Foinquinos, A., Hirt, M. N., Eschenhagen, T., Funcke, S., Stojanovic, S., Genschel, C., Schimmel, K., Just, A., Pfanne, A., Scherf, K., Dehmel, S., Raemon-Buettner, S. M., & 2 othersFiedler, J. & Thum, T., 6 Dec 2019, In: Molecular Therapy - Nucleic Acids. 18, p. 363-374 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2018

  Assessing fatty acid oxidation flux in rodent cardiomyocyte models

  Rech, M., Luiken, J. J. F. P., Glatz, J. F. C., van Bilsen, M., Schroen, B. & Nabben, M., 24 Jan 2018, In: Scientific Reports. 8, 6 p., 1505.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• MicroRNA-155 Amplifies Nitric Oxide/cGMP Signaling and Impairs Vascular Angiotensin II Reactivity in Septic Shock

  Vasques-Novoa, F., Laundos, T. L., Cerqueira, R. J., Quina-Rodrigues, C., Soares-dos-Reis, R., Baganha, F., Ribeiro, S., Mendonca, L., Goncalves, F., Reguenga, C., Verhesen, W., Carneiro, F., Paiva, J. A., Schroen, B., Castro-Chaves, P., Pinto-do-O, P., Nascimento, D. S., Heymans, S., Leite-Moreira, A. F. & Roncon-Albuquerque, R., 1 Sept 2018, In: Critical Care Medicine. 46, 9, p. E945-E954 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload-Induced Heart Failure

  Verjans, R., Peters, T., Beaumont, F., van Leeuwen, R., van Herwaarden, T., Verhesen, W., Munts, C., Bijnen, M., Henkens, M., Diez, J., de Windt, L. J., van Nieuwenhoven, F. A., van Bilsen, M., Goumans, M. J., Heymans, S., Gonzalez, A. & Schroen, B., 1 Feb 2018, In: Hypertension. 71, 2, p. 280-288 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Sex-specific associations of obesity and N-terminal pro-B-type natriuretic peptide levels in the general population

  Suthahar, N., Meijers, W. C., Ho, J. E., Gansevoort, R. T., Voors, A. A., van der Meer, P., Bakker, S. J. L., Heymans, S., van Empel, V., Schroen, B., van der Harst, P., van Veldhuisen, D. J. & de Boer, R. A., 1 Aug 2018, In: European journal of heart failure. 20, 8, p. 1205-1214 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2017

  Cartilage intermediate layer protein 1 (CILP1): A novel mediator of cardiac extracellular matrix remodelling

  van Nieuwenhoven, F. A., Munts, C., op't Veld, R. C., Gonzalez, A., Diez, J., Heymans, S., Schroen, B. & van Bilsen, M., 22 Nov 2017, In: Scientific Reports. 7, 9 p., 16042.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Expression of RMRP RNA is regulated in chondrocyte hypertrophy and determines chondrogenic differentiation

  Steinbusch, M. M. F., Caron, M. M. J., Surtel, D. A. M., Friedrich, F., Lausch, E., Pruijn, G. J. M., Verhesen, W., Schroen, B. L. M., van Rhijn, L. W., Zabel, B. & Welting, T. J. M., 25 Jul 2017, In: Scientific Reports. 7, 15 p., 6440.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction

  Heggermont, W. A., Papageorgiou, A-P., Quaegebeur, A., Deckx, S., Carai, P., Verhesen, W., Eelen, G., Schoors, S., van Leeuwen, R., Alekseev, S., Elzenaar, I., Vinckier, S., Pokreisz, P., Walravens, A-S., Gijsbers, R., Van Den Haute, C., Nickel, A., Schroen, B., van Bilsen, M., Janssens, S., & 4 othersMaack, C., Pinto, Y., Carmeliet, P. & Heymans, S., 22 Aug 2017, In: Circulation. 136, 8, p. 747-761 33 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The long noncoding RNA Wisper controls cardiac fibrosis and remodeling

  Micheletti, R., Plaisance, I., Abraham, B. J., Sarre, A., Ting, C-C., Alexanian, M., Maric, D., Maison, D., Nemir, M., Young, R. A., Schroen, B., Gonzalez, A., Ounzain, S. & Pedrazzini, T., 21 Jun 2017, In: Science Translational Medicine. 9, 395, 17 p., eaai9118.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function

  McDermott-Roe, C., Leleu, M., Rowe, G. C., Palygin, O., Bukowy, J. D., Kuo, J., Rech, M., Hermans-Beijnsberger, S., Schaefer, S., Adami, E., Creemers, E. E., Heinig, M., Schroen, B., Arany, Z., Petretto, E. & Geurts, A. M., 3 Feb 2017, In: PLOS ONE. 12, 2, 20 p., 0170458.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2016

  Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity

  Gast, M., Schroen, B., Voigt, A., Haas, J., Kuehl, U., Lassner, D., Skurk, C., Escher, F., Wang, X., Kratzer, A., Michalik, K., Papageorgiou, A., Peters, T., Loebel, M., Wilk, S., Althof, N., Prasanth, K. V., Katus, H., Meder, B., Nakagawa, S., & 6 othersScheibenbogen, C., Schultheiss, H-P., Landmesser, U., Dimmeler, S., Heymans, S. & Poller, W., Apr 2016, In: Journal of Molecular Cell Biology. 8, 2, p. 178-181

  Research output: Contribution to journal › Article › Academic › peer-review

• Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice

  Peters, T., Beijnsberger, S., Beqqali, A., Bitsch, N., Nakagawa, S., Prasanth, K. V., de Windt, L. J., van Oort, R. J., Heymans, S. & Schroen, B., 26 Feb 2016, In: PLOS ONE. 11, 2, e0150236.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• RNA Profiling in Human and Murine Transplanted Hearts: Identification and Validation of Therapeutic Targets for Acute Cardiac and Renal Allograft Rejection

  Van Aelst, L. N. L., Summer, G., Li, S., Gupta, S. K., Heggermont, W., De Vusser, K., Carai, P., Naesens, M., Van Cleemput, J., Van de Werf, F., Vanhaecke, J., Thum, T., Waer, M., Papageorgiou, A. -P., Schroen, B. & Heymans, S., Jan 2016, In: American Journal of Transplantation. 16, 1, p. 99-110 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2015

  CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis

  Ounzain, S., Micheletti, R., Arnan, C., Plaisance, I., Cecchi, D., Schroen, B., Reverter, F., Alexanian, M., Gonzales, C., Ng, S. Y., Bussotti, G., Pezzuto, I., Notredame, C., Heymans, S., Guigo, R., Johnson, R. & Pedrazzini, T., Dec 2015, In: Journal of Molecular and Cellular Cardiology. 89, p. 98-112

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

  Ounzain, S., Micheletti, R., Beckmann, T., Schroen, B., Alexanian, M., Pezzuto, I., Crippa, S., Nemir, M., Sarre, A., Johnson, R., Dauvillier, J., Burdet, F., Ibberson, M., Guigo, R., Xenarios, I., Heymans, S. & Pedrazzini, T., 7 Feb 2015, In: European Heart Journal. 36, 6, p. 353–368

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Long noncoding RNAs in cardiac development and ageing

  Devaux, Y., Zangrando, J., Schroen, B., Creemers, E. E., Pedrazzini, T., Chang, C-P., Dorn, G. W. . II., Thum, T. & Heymans, S., Jul 2015, In: Nature Reviews Cardiology. 12, 7, p. 415-425

  Research output: Contribution to journal › Article › Academic › peer-review

• The microRNA-221/-222 cluster balances the antiviral and inflammatory response in viral myocarditis

  Corsten, M., Heggermont, W., Papageorgiou, A-P., Deckx, S., Tijsma, A., Verhesen, W., van Leeuwen, R., Carai, P., Thibaut, H-J., Custers, K., Summer, G., Hazebroek, M., Verheyen, F., Neyts, J., Schroen, B. & Heymans, S., 7 Nov 2015, In: European Heart Journal. 36, 42, p. 2909-U56

  Research output: Contribution to journal › Article › Academic › peer-review
• 2014

  microRNA-122 down-regulation may play a role in severe myocardial fibrosis in human aortic stenosis through TGF-beta(1) up-regulation

  Beaumont, J., Lopez, B., Hermida, N., Schroen, B., Jose, G. S., Heymans, S., Valencia, F., Jose Gomez-Doblas, J., De Teresa, E., Diez, J. & Gonzalez, A., Apr 2014, In: Clinical Science. 126, 7-8, p. 497-506

  Research output: Contribution to journal › Article › Academic › peer-review

• Missing links in cardiology: long non-coding RNAs enter the arena

  Peters, T. & Schroen, B., Jun 2014, In: Pflugers Archiv-European Journal of Physiology. 466, 6, p. 1177-1187

  Research output: Contribution to journal › Article › Academic › peer-review

• The microRNA-15 family inhibits the TGF beta-pathway in the heart

  Tijsen, A. J., van der Made, I., van den Hoogenhof, M. M., Wijnen, W. J., van Deel, E. D., de Groot, N. E., Alekseev, S., Fluiter, K., Schroen, B., Goumans, M-J., van der Velden, J., Duncker, D. J., Pinto, Y. M. & Creemers, E. E., 1 Oct 2014, In: Cardiovascular Research. 104, 1, p. 61-71

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2013

  Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure

  Heymans, S., Corsten, M. F., Verhesen, W., Carai, P., van Leeuwen, R. E., Custers, K., Peters, T., Hazebroek, M., Stoger, L., Wijnands, E., Janssen, B. J., Creemers, E. E., Pinto, Y. M., Grimm, D., Schurmann, N., Vigorito, E., Thum, T., Stassen, F. R., Yin, X., Mayr, M., & 9 othersDe Windt, L. J., Lutgens, E., Wouters, K., de Winther, M. P., Zacchigna, S., Giacca, M., van Bilsen, M., Papageorgiou, A. P. & Schroen, B. L., 24 Sept 2013, In: Circulation. 128, 13, p. 1420-1432

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2012

  Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice

  Donners, M. M. P. C., Wolfs, I. M. J., Stoger, L. J., van der Vorst, E. P. C., Pottgens, C. C. H., Heymans, S., Schroen, B., Gijbels, M. J. J. & de Winther, M. P. J., 25 Apr 2012, In: PLOS ONE. 7, 4, e35877.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Inflammation in viral myocarditis: friend or foe?

  Corsten, M. F., Schroen, B. & Heymans, S., Jul 2012, In: Trends in Molecular Medicine. 18, 7, p. 426-437

  Research output: Contribution to journal › Article › Academic › peer-review

• Small but smart-microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing

  Schroen, B. & Heymans, S., 15 Mar 2012, In: Cardiovascular Research. 93, 4, p. 605-613

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Use of Circulating MicroRNAs to Diagnose Acute Myocardial Infarction

  Devaux, Y., Vausort, M., Goretti, E., Nazarov, P. V., Azuaje, F., Gilson, G., Corsten, M. F., Schroen, B., Lair, M-L., Heymans, S. & Wagner, D. R., Mar 2012, In: Clinical Chemistry. 58, 3, p. 559-567

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2011

  Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy

  van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P. & Heymans, S., Sept 2011, In: Journal of Molecular and Cellular Cardiology. 51, 3, p. 318-328

  Research output: Contribution to journal › Article › Academic › peer-review

• MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure

  van Almen, G. C., Verhesen, W., van Leeuwen, R. E. W., van de Vrie, M., Eurlings, C., Schellings, M. W. M., Swinnen, M., Cleutjens, J. P. M., van Zandvoort, M. A. M. J., Heymans, S. & Schroen, B., Oct 2011, In: Aging Cell. 10, 5, p. 769-779

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• MicroRNA Involvement in Immune Activation During Heart Failure

  van de Vrie, M., Heymans, S. & Schroen, B., Apr 2011, In: Cardiovascular Drugs and Therapy. 25, 2, p. 161-170

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2006

  Biologically relevant effects of mRNA amplification on gene expression profiles

  van Haaften, R. I. M., Schroen, B. L., Janssen, B. J., van Erk, A. A., Debets, J. J., Smeets, H. J., Smits, J. F., van den Wijngaard, A., Pinto, Y. M. & Evelo, C. T., 1 Jan 2006, In: BMC Bioinformatics. 7, p. 200

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access