1990 …2020

Research output per year

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Research Output

2009

Pharmacokinetics of acute tryptophan depletion using a gelatin-based protein in male and female Wistar rats

Jans, L. A. W., Lieben, C. K. J., Smits, L. T. & Blokland, A., 1 Jan 2009, In : Amino Acids. 37, 2, p. 349-357

Research output: Contribution to journalArticleAcademicpeer-review

Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats

Rutten, K., van Donkelaar, E. L., Ferrington, L., Blokland, A., Bollen, E., Steinbusch, H. W. M., Kelly, P. A. & Prickaerts, J. H. H. J., 1 Jan 2009, In : Neuropsychopharmacology. 34, 8, p. 1914-1925

Research output: Contribution to journalArticleAcademicpeer-review

Selective phosphodiesterase inhibitors: a promising target for cognition enhancement

Reneerkens, O. A. H., Rutten, K., Steinbusch, H. W. M., Blokland, A. & Prickaerts, J. H. H. J., 1 Jan 2009, In : Psychopharmacology. 202, 1-3, p. 419-443

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Serotonin transporter deficiency in rats contributes to impaired object memory

Olivier, J. D., Jans, L. A. W., Blokland, A., Broers, N. J., Homberg, J. R., Ellenbroek, B. A. & Cools, A. R., 1 Jan 2009, In : Genes, Brain and Behavior. 8, 8, p. 829-834

Research output: Contribution to journalArticleAcademicpeer-review

The role of serotonin and acetylcholine in mismatch negativity generation

Sambeth, A., Blokland, A., Kähkönen, S. & Riedel, W., 1 Jan 2009, p. 72.

Research output: Contribution to conferenceAbstractAcademic

2008

Acetylcholine but not serotonin is involved in novelty processing: an EEG study in humans

Sambeth, A., Blokland, A. & Riedel, W. J., 1 Jan 2008, p. 95-95.

Research output: Contribution to conferenceAbstractAcademic

Acute tryptophan depletion dose dependently impairs object memory in serotonin transporter knockout rats

Olivier, J., Jans, L. A. W., Korte-Bouws, G. A. H., Korte, S., Deen, P. M. T., Cools, A. R., Ellenbroek, B. A. & Blokland, A., 1 Jan 2008, In : Psychopharmacology. 200, 2, p. 243-254

Research output: Contribution to journalArticleAcademicpeer-review

Automated scoring of novel object recognition in rats

Rutten, K., Reneerkens, O. A. H., Hamers, H., Sik, A., McGregor, I. S., Prickaerts, J. H. H. J. & Blokland, A., 1 Jan 2008, In : Journal of Neuroscience Methods. 171, 1, p. 72-77

Research output: Contribution to journalArticleAcademicpeer-review

Buspirone induced acute and chronic changes of neural activation in the periaqueductal gray of rats

Lim, L. W., Temel, Y., Sesia, T. J. J., Vlamings, R., Visser-Vandewalle, V. E. R. M., Steinbusch, H. P. & Blokland, A., 1 Jan 2008, In : Neuroscience. 155, 1, p. 164-173

Research output: Contribution to journalArticleAcademicpeer-review

Deep brain stimulation of the nucleus accumbens core and shell: Opposite effects on impulsive action

Sesia, T. J. J., Temel, Y., Lim, L. W., Blokland, A., Steinbusch, H. P. & Visser-Vandewalle, V. E. R. M., 1 Jan 2008, In : Experimental Neurology. 214, 1, p. 135-139

Research output: Contribution to journalArticleAcademicpeer-review

Effect of buspirone on the behavioral regulation of rats in low versus high anxiety conditions

Lim, L. W., Temel, Y., Visser-Vandewalle, V. E. R. M., Steinbusch, H. P. J., Schruers, K. R. J., Hameleers, R., Esquivel, G., Griez, E. J. L. & Blokland, A., 1 Jan 2008, In : Arzneimittelforschung : Drug Research. 58, 6, p. 269-276

Research output: Contribution to journalArticleAcademicpeer-review

Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D(-/-)) mice

Rutten, K., Misner, D. L., Works, M., Blokland, A., Novak, T. J., Santarelli, L. & Wallace, T., 1 Jan 2008, In : European Journal of Neuroscience. 28, 3, p. 625-632

Research output: Contribution to journalArticleAcademicpeer-review

High-frequency stimulation of the dorsolateral periaqueductal gray and ventromedial hypothalamus fails to inhibit panic-like behaviour

Lim, L. W., Blokland, A., Visser-Vandewalle, V. E. R. M., Vlamings, R., Sesia, T. J. J., Steinbusch, H. P. J., Schruers, K. R. J., Griez, E. J. L. & Temel, Y., 1 Jan 2008, In : Behavioural Brain Research. 193, 2, p. 197-203

Research output: Contribution to journalArticleAcademicpeer-review

Human apolipoprotein C-I expression in mice impairs learning and memory functions

Abildayeva, K., Berbee, J. F., Blokland, A., Jansen, P. J., Hoek, F., Meijer, O., Lutjohann, D., Gautier, T., Pillot, T., de Vente, J., Havekes, L. M., Ramaekers, F. C. S., Kuipers, F., Rensen, P. C. & Mulder, M. T., 1 Jan 2008, In : Journal of Lipid Research. 49, 4, p. 856-869

Research output: Contribution to journalArticleAcademicpeer-review

Influence of chronic mild stress on the behavioural effects of acute tryptophan depletion induced by a gelatin-based mixture

Jans, L. A. W. & Blokland, A., 1 Jan 2008, In : Behavioural Pharmacology. 19, 7, p. 706-715

Research output: Contribution to journalArticleAcademicpeer-review

Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion

van Donkelaar, E. L., Rutten, K., Blokland, A., Akkerman, S., Steinbusch, H. P. & Prickaerts, J. H. H. J., 1 Jan 2008, In : European Journal of Pharmacology. 600, 1-3, p. 98-104

Research output: Contribution to journalArticleAcademicpeer-review

Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques

Rutten, K., Basile, J. L., Prickaerts, J. H. H. J., Blokland, A. & Vivian, J., 1 Jan 2008, In : Psychopharmacology. 196, 4, p. 643-648

Research output: Contribution to journalArticleAcademicpeer-review

Sub-chronic rolipram treatment leads to a persistent improvement in long-term object memory in rats

Rutten, K., Prickaerts, J. H. H. J., Schaenzle, G., Rosenbrock, H. & Blokland, A., 1 Jan 2008, In : Neurobiology of Learning and Memory. 90, 3, p. 569-575

Research output: Contribution to journalArticleAcademicpeer-review

The novel selective PDE9 inhibitor BAY 73-6691 improves learning and memory in rodents

van der Staay, F. J., Rutten, K., Barfacker, L., Devry, J., Erb, C., Heckroth, H., Karthaus, D., Tersteegen, A., van Kampen, M., Blokland, A., Prickaerts, J. H. H. J., Reymann, K. G., Schroder, U. H. & Hendrix, M., 1 Jan 2008, In : Neuropharmacology. 55, 5, p. 908-918

Research output: Contribution to journalArticleAcademicpeer-review

Use of behavioral and LTP models in the development of memory-improving drugs

Blokland, A. & Boess, F., 1 Jan 2008, In : Expert Opinion on Drug Discovery. 3, p. 1067-1080

Research output: Contribution to journalArticleAcademicpeer-review

Women and serotonergic vulnerability

Jans, L. & Blokland, A., 1 Jan 2008, New perspectives on women and depression. Hansson, W. & Olson, E. (eds.). New York: Nova Science Publishers, p. 267-293 316 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

2007

Cholinergic drugs affect novel object recognition in rats: relation with hippocampal EEG?

Sambeth, A., Riedel, W., Smits, L. & Blokland, A., 1 Jan 2007, In : European Journal of Pharmacology. 572, p. 151-159

Research output: Contribution to journalArticleAcademicpeer-review

Effects of right-hemisphere cortical infarction and muscarinic acetylcholine receptor blockade on spatial visual attention performance in rats

Hoff, E. I., van Oostenbrugge, R. J., Liedenbaum, M., Steinbusch, H. P. J. & Blokland, A., 1 Jan 2007, In : Behavioural Brain Research. 178, 1, p. 62-69

Research output: Contribution to journalArticleAcademicpeer-review

Effects of the novel 5-HT(6) receptor antagonist RO4368554 in rat models for cognition and sensorimotor gating

Schreiber, R., Vivian, J., Hedley, L., Szczepanski, K., Secchi, R. L., Zuzow, M., van Laarhoven, S., Moreau, J. L., Martin, J. R., Sik, A. & Blokland, A., 1 Jan 2007, In : European Neuropsychopharmacology. 17 (4), p. 277-288

Research output: Contribution to journalArticleAcademicpeer-review

Hypomobility after DOI administration can be reversed by subthalamic nucleus deep brain stimulation

Hameleers, R., Blokland, A., Steinbusch, H. W. M., Visser-Vandewalle, V. & Temel, Y., 1 Jan 2007, In : Behavioural Brain Research. 185 (1), p. 65-7

Research output: Contribution to journalArticleAcademicpeer-review

Influence of sex and estrous cycle on the effects of acute tryptophan depletion induced by a gelatin-based mixture in adult Wistar rats

Jans, L. A., Lieben, C. K. & Blokland, A., 1 Jan 2007, In : Neuroscience. 147, 2, p. 304-317

Research output: Contribution to journalArticleAcademicpeer-review

Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus

Temel, Y., Boothman, L. J., Blokland, A., Magill, P. J., Steinbusch, H. W. M., Visser-Vandewalle, V. & Sharp, T., 1 Jan 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 43, p. 17087-17092

Research output: Contribution to journalArticleAcademicpeer-review

Lack of evidence for reduced prefrontal cortical serotonin and dopamine efflux after acute tryptophan depletion

van der Plasse, G., Meerkerk, D. T., Lieben, C. K., Blokland, A. & Feenstra, M. G., 1 Jan 2007, In : Psychopharmacology. 195, p. 377-385

Research output: Contribution to journalArticleAcademicpeer-review

LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus

Mulder, M. T., Koopmans, G., Wassink, G., Al Mansouri, G., Simard, M. L., Havekes, L. M., Prickaerts, J. H. H. J. & Blokland, A., 1 Jan 2007, In : Neuroscience Research. 59, 3

Research output: Contribution to journalArticleAcademicpeer-review

Relating psychiatric disorders, offender and offence characteristics in a sample of adolescent sex offenders and non-sex offenders

van Wijk, A. P., Blokland, A., Duits, N., Vermeiren, R. & Harkink, J., 1 Jan 2007, In : Criminal behaviour and mental health. 17, 1, p. 15-30

Research output: Contribution to journalArticleAcademicpeer-review

Serotonergic vulnerability and depression: assumptions, experimental evidence and implications

Jans, L. A. W., Riedel, W. J., Markus, C. R. & Blokland, A., 1 Jan 2007, In : Molecular Psychiatry. 12, 6, p. 522-543

Research output: Contribution to journalArticleAcademicpeer-review

Sex differences in the effect of acute tryptophan depletion on declarative episodic memory: a pooled analysis of nine studies

Sambeth, A., Blokland, A., Harmer, C. J., Kilkens, T. O. C., Nathan, P. J., Porter, R. J., Schmitt, J. A. J., Scholtissen, B., Sobczak, S., Young, A. H. & Riedel, W. J., 1 Jan 2007, In : Neuroscience and Biobehavioral Reviews. 31, 4, p. 516-529

Research output: Contribution to journalArticleAcademicpeer-review

The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat

Rutten, K., Lieben, C., Smits, L. & Blokland, A., 1 Jan 2007, In : Psychopharmacology. 192, p. 275-282

Research output: Contribution to journalArticleAcademicpeer-review

Time-dependent involvement of cAMP and cGMP in consolidation of object memory: Studies using selective phosphodiesterase type 2, 4 and 5 inhibitors

Rutten, K., Prickaerts, J. H. H. J., Hendrix, M., van der Staay, F. J., Sik, A. & Blokland, A., 1 Jan 2007, In : European Journal of Pharmacology. 558, 1-3, p. 107-112

Research output: Contribution to journalArticleAcademicpeer-review

2006

5,7-DHT lesion of the dorsal raphe nuclei impairs object recognition but not affective behavior and corticosterone response to stressor in the rat.

Lieben, C. K. J., Steinbusch, H. P. J. & Blokland, A., 1 Jan 2006, In : Behavioural Brain Research. 168, 2, p. 197-207

Research output: Contribution to journalArticleAcademicpeer-review

Analysis of spatial orientation strategies of male and female Wistar rats in a Morris water escape task

Blokland, A., Rutten, K. & Prickaerts, J. H. H. J., 1 Jan 2006, In : Behavioural Brain Research. 171, p. 216-224

Research output: Contribution to journalArticleAcademicpeer-review

Differential effects of subthalamic nucleus stimulation in advanced Parkinson disease on reaction time performance.

Temel, Y., Blokland, A., Ackermans, L., Boon, P., van Kranen-Mastenbroek, V. H. J. M., Beuls, E. A., Spincemaille, G. H. J. J. & Visser-Vandewalle, V., 1 Jan 2006, In : Experimental Brain Research. 169, 3, p. 389-399

Research output: Contribution to journalArticleAcademicpeer-review

Dissociable effects in reaction time performance after unilateral cerebral infarction: a comparison between the left and right frontal cortices in rats

Hoff, E. I., Blokland, A., Rutten, K., Steinbusch, H. W. & van Oostenbrugge, R. J., 1 Jan 2006, In : Brain Research. 1069, 1, p. 182-189

Research output: Contribution to journalArticleAcademicpeer-review

Functional investigations into the role of dopamine and serotonin in partial bilateral striatal 6-hydroxydopamine lesioned rats

Scholtissen, B., Deumens, R., Leentjens, A. F. G., Schmitz, C., Blokland, A., Steinbusch, H. W. M. & Prickaerts, J. H. H. J., 1 Jan 2006, In : Pharmacology, Biochemistry and Behavior. 83, p. 175-85

Research output: Contribution to journalArticleAcademicpeer-review

Improving memory: a role for phosphodiesterases

Blokland, A., Schreiber, R. & Prickaerts, J. H. H. J., 1 Jan 2006, In : Current Pharmaceutical Design. 12, p. 2511-2523

Research output: Contribution to journalArticleAcademicpeer-review

Motor and cognitive improvement by deep brain stimulation in a transgenic rat model of Huntington's disease

Temel, Y., Cao, C., Vlamings, R., Blokland, A., Ozen, H., Steinbusch, H. W., Michelsen, K. A., von Horsten, S., Schmitz, C. & Vandewalle, V., 1 Jan 2006, In : Neuroscience Letters. 406, p. 138-141

Research output: Contribution to journalArticleAcademicpeer-review

Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel

Cao, C., Temel, Y., Blokland, A., Ozen, H., Steinbusch, H. W. M., Vlamings, R., Nguyen, H. P., von Horsten, S., Schmitz, C. & Visser-Vandewalle, V., 1 Jan 2006, In : Behavioural Brain Research. 170, 2, p. 257-261

Research output: Contribution to journalArticleAcademicpeer-review

Protection of nigral cell death by bilateral subthalamic nucleus stimulation

Temel, Y., Visser-Vandewalle, V., Kaplan, S., Kozan, R., Daemen, M. A. R. C., Blokland, A., Schmitz, C. & Steinbusch, H. W., 1 Jan 2006, In : Brain Research. 1120, 1, p. 100-105

Research output: Contribution to journalArticleAcademicpeer-review

Rolipram reverses scopolamine-induced and time-dependent memory deficits in object recognition by different mechanisms of action

Rutten, K., Prickaerts, J. H. H. J. & Blokland, A., 1 Jan 2006, In : Neurobiology of Learning and Memory. 85, 2, p. 132-138

Research output: Contribution to journalArticleAcademicpeer-review

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

Kantor, O., Temel, Y., Holzmann, C., Raber, K., Nguyen, H. P., Cao, C., Turkoglu, H. O., Rutten, B. P., Visser-Vandewalle, V., Steinbusch, H. W., Blokland, A., Korr, H., Riess, O., von Horsten, S. & Schmitz, C., 1 Jan 2006, In : Neurobiology of Disease. 22, p. 538-547

Research output: Contribution to journalArticleAcademicpeer-review

The subthalamic nucleus: From response selection to execution

Tan, S. K., Temel, Y., Blokland, A., Steinbusch, H. W. & Vandewalle, V., 1 Jan 2006, In : Journal of Chemical Neuroanatomy. 31, p. 155-161

Research output: Contribution to journalArticleAcademicpeer-review

2005

Acute and separate modulation of motor and cognitive performance in parkinsonian rats by bilateral stimulation of the subthalamic nucleus.

Temel, Y., Visser-Vandewalle, V., Aendekerk, B., Rutten, B. P. F., Tan, S. K. H., Scholtissen, B., Schmitz, C., Blokland, A. & Steinbusch, H. W. M., 1 Jan 2005, In : Experimental Neurology. 193, 1, p. 43-52

Research output: Contribution to journalArticleAcademicpeer-review

Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation

Prickaerts, J. H. H. J., Sik, A., van der Staay, F. J., de Vente, J. & Blokland, A., 1 Jan 2005, In : Psychopharmacology. 177, p. 381-90

Research output: Contribution to journalArticleAcademicpeer-review