20102020

Research output per year

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Research Output

2016

Is selective nodal irradiation in non-small cell lung cancer still safe when using IMRT? Results of a prospective cohort study

Martinussen, H. M. A., Reymen, B., Wanders, R., Troost, E. G. C., Dingemans, A-M. C., Öllers, M., Houben, R., De Ruysscher, D., Lambin, P. & van Baardwijk - Renkens, A., Nov 2016, In : Radiotherapy and Oncology. 121, 2, p. 322-327

Research output: Contribution to journalArticleAcademicpeer-review

Medicamenteuze behandeling van kankercachexie

de Vos-Geelen, J. M. P. G. M., Sanders, K., Schols, A. & Dingemans, A-M., 2016, In : Nederlands Tijdschrift voor Oncologie. 13, 3, p. 72-80

Research output: Contribution to journalArticleAcademicpeer-review

Neuroendocrine Cancer of the Lung: A Diagnostic Puzzle

Derks, J., Speel, E., Thunnissen, E., van Suylen, R. J., Buikhuisen, W. A., van Velthuysen, M-L. & Dingemans, A-M., Mar 2016, In : Journal of Thoracic Oncology. 11, 3, p. e35-e38 7 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Pemetrexed plus carboplatin versus pemetrexed in pretreated patients with advanced non-squamous non-small-cell lung cancer: treating the right patients based on individualized treatment effect prediction

van Kruijsdijk, R. C. M., Visseren, F. L. J., Boni, L., Groen, H. J. M., Dingemans, A. M. C., Aerts, J. G. J. V., van der Graaf, Y., Ardizzoni, A. & Smit, E. F., Jul 2016, In : Annals of Oncology. 27, 7, p. 1280-1286

Research output: Contribution to journalArticleAcademicpeer-review

Proposals for the M-descriptors of the Eight TNM Classification for Non–Small Cell Lung Cancer: Are More Data Needed?

Hendriks, L., Dingemans, A-M. & de Ruysscher, D., Mar 2016, In : Journal of Thoracic Oncology. 11, 3, p. e42-e43 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Open Access

Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer

Nilsson, R. J. A., Karachaliou, N., Berenguer, J., Gimenez-Capitan, A., Schellen, P., Teixido, C., Tannous, J., Kuiper, J. L., Drees, E., Grabowska, M., van Keulen, M., Heideman, D. A. M., Thunnissen, E., Dingemans, A-M. C., Viteri, S., Tannous, B. A., Drozdowskyj, A., Rosell, R., Smit, E. F. & Wurdinger, T., 5 Jan 2016, In : Oncotarget. 7, 1, p. 1066-1075

Research output: Contribution to journalArticleAcademicpeer-review

Selective mediastinal node irradiation in non-small cell lung cancer in the IMRT/VMAT era: How to use E(B)US-NA information in addition to PET-CT for delineation?

Peeters, S. T., Dooms, C., van Baardwijk - Renkens, A., Dingemans, A-M. C., Martinussen, H., Vansteenkiste, J., Decaluwe, H., De Leyn, P., Yserbyt, J., Nackaerts, K., De Wever, W., Deroose, C. M. & De Ruysscher, D., Aug 2016, In : Radiotherapy and Oncology. 120, 2, p. 273-278

Research output: Contribution to journalArticleAcademicpeer-review

Stage III Non-Small Cell Lung Cancer in the elderly: Patient characteristics predictive for tolerance and survival of chemoradiation in daily clinical practice

Driessen, E. J. M., Bootsma, G. P., Hendriks, L. E. L., van den Berkmortel, F. W. P. J., Bogaarts, B. A. H. A., van Loon, J. G. M., Dingemans, A-M. C. & Janssen - Heijnen, M., Oct 2016, In : Radiotherapy and Oncology. 121, 1, p. 26-31

Research output: Contribution to journalArticleAcademicpeer-review

The Optimal Local Treatment of Stage IIIA-N2 NSCLC: Is the Issue Finally Settled?

De Ruysscher, D., Vansteenkiste, J., Belderbos, J., Decaluwe, H. & Dingemans, A-M., Mar 2016, In : Journal of Thoracic Oncology. 11, 3, p. 284-286 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Updated efficacy and safety from the global phase II NP28673 study of alectinib in patients (pts) with previously treated ALK plus non-small-cell lung cancer (NSCLC)

Barlesi, F., Dingemans, A-M. C., Yang, J. C-H., Ou, S-H. I., Ahn, J. S., De Petris, L., Hughes, B., Lena, H., Bordogna, W., Golding, S., Morcos, P. N., Balas, B., Zeaiter, A. & Kim, D-W., 1 Oct 2016, In : Annals of Oncology. 27, supp. 6, 1 p., 1263P.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

2015

An Uncommon Presentation of Brain Metastases in a Lung Cancer Patient

Hendriks, L., Dingemans, A-M. C., Lammens, M., Anten, M. M., van den Heuvel, M. M. & Postma, L. A., Nov 2015, In : Journal of Thoracic Oncology. 10, 11, p. 1655-1656

Research output: Contribution to journalArticleAcademicpeer-review

A randomized phase II study comparing paclitaxel-carboplatin-bevacizumab with or without nitroglycerin patches in patients with stage IV nonsquamous nonsmall-cell lung cancer: NVALT12 (NCT01171170)(aEuro)

Dingemans, A. -M. C., Groen, H. J. M., Herder, G. J. M., Stigt, J. A., Smit, E. F., Bahce, I., Burgers, J. A., van den Borne, B. E. E. M., Biesma, B., Vincent, A., van der Noort, V. & Aerts, J. G., Nov 2015, In : Annals of Oncology. 26, 11, p. 2286-2293

Research output: Contribution to journalArticleAcademicpeer-review

A Validated Prediction Model for Overall Survival From Stage III Non-Small Cell Lung Cancer: Toward Survival Prediction for Individual Patients

Oberije, C., De Ruysscher, D., Houben, R., van de Heuvel, M., Uyterlinde, W., Deasy, J. O., Belderbos, J., Dingemans, A-M. C., Rimner, A., Din, S. & Lambin, P., 15 Jul 2015, In : International Journal of Radiation Oncology Biology Physics. 92, 4, p. 935-944

Research output: Contribution to journalArticleAcademicpeer-review

Comparison of clinical outcome after first-line platinum-based chemotherapy in different types of KRAS mutated advanced non-small-cell lung cancer

Mellema, W. W., Masen-Poos, L., Smit, E. F., Hendriks, L. E. L., Aerts, J. G., Termeer, A., Goosens, M. J., Smit, H. J. M., van den Heuvel, M. M., van der Wekken, A. J., Herder, G. J. M., Krouwels, F. H., Stigt, J. A., van den Borne, B. E. E. M., Haitjema, T. J., Staal-Van den Brekel, A. J., van Heemst, R. C., Pouw, E. & Dingemans, A-M. C., Nov 2015, In : Lung Cancer. 90, 2, p. 249-254

Research output: Contribution to journalArticleAcademicpeer-review

Crizotinib Therapy for Advanced Lung Adenocarcinoma and a ROS1 Rearrangement: Results From the EUROS1 Cohort

Mazieres, J., Zalcman, G., Crino, L., Biondani, P., Barlesi, F., Filleron, T., Dingemans, A-M. C., Lena, H., Monnet, I., Rothschild, S. I., Cappuzzo, F., Besse, B., Thiberville, L., Rouviere, D., Dziadziuszko, R., Smit, E. F., Wolf, J., Spirig, C., Pecuchet, N., Leenders, F. & 5 others, Heuckmann, J. M., Diebold, J., Milia, J. D., Thomas, R. K. & Gautschi, O., 20 Mar 2015, In : Journal of Clinical Oncology. 33, 9, p. 992-+

Research output: Contribution to journalArticleAcademicpeer-review

CT-Guided Percutaneous Transthoracic Needle Biopsies Using 10G Large-Core Needles: Initial Experience

Lalji, U. C., Wildberger, J. E., Hausen, A. Z., Bendek, M., Dingemans, A-M. C., Hochstenbag, M. & Das, M., Dec 2015, In : Cardiovascular and Interventional Radiology. 38, 6, p. 1603-1610

Research output: Contribution to journalArticleAcademicpeer-review

Detection of Human Polyomavirus 7 in Human Thymic Epithelial Tumors

Rennspiess, D., Pujari, S., Keijzers, M., Abdul-Hamid, M. A., Hochstenbag, M., Dingemans, A-M., Kurz, A. K., Speel, E-J., Haugg, A., Pastrana, D. V., Buck, C. B., De Baets, M. H. & zur Hausen, A., Feb 2015, In : Journal of Thoracic Oncology. 10, 2, p. 360-366

Research output: Contribution to journalArticleAcademicpeer-review

Difference in Outcome between Types of KRAS Mutation May Point toward Difference in Tumor Biology

Mellema, W. W., Dingemans, A-M. C., Jonker, M. & Smit, E. F., Feb 2015, In : Journal of Thoracic Oncology. 10, 2, p. E9-E9

Research output: Contribution to journalArticleAcademicpeer-review

Do associated auto-antibodies influence the outcome of myasthenia gravis after thymectomy?

Keijzers, M., Damoiseaux, J., Vigneron, A., Bodart, N., Kessels, A., Dingemans, A-M. C., Hochstenbag, M., Maessen, J. & De Baets, M., 17 Nov 2015, In : Autoimmunity. 48, 8, p. 552-555

Research output: Contribution to journalArticleAcademicpeer-review

Expression of pRb and p16INK4 in human thymic epithelial tumors in relation to the presence of human polyomavirus 7

Keijzers, M., Rensspiess, D., Pujari, S., Abdul-Hamid, M. A., Hochstenbag, M., Dingemans, A-M., Kurz, A. K., Haugg, A., Maessen, J. G., De Baets, M. H. & zur Hausen, A., 4 Nov 2015, In : Diagnostic Pathology. 10, 201.

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin-like transcript 3 is expressed by myeloid-derived suppressor cells and correlates with survival in patients with non-small cell lung cancer

de Goeje, P. L., Bezemer, K., Heuvers, M. E., Dingemans, A-M. C., Groen, H. J. M., Smit, E. F., Hoogsteden, H. C., Hendriks, R. W., Aerts, J. G. J. V. & Hegmans, J. P. J. J., 2015, In : OncoImmunology . 4, 7, e1014242.

Research output: Contribution to journalArticleAcademicpeer-review

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy

van den Heuvel, M. M., Verheij, M., Boshuizen, R., Belderbos, J., Dingemans, A-M. C., De Ruysscher, D., Laurent, J., Tighe, R., Haanen, J. & Quaratino, S., 27 Jan 2015, In : Journal of Translational Medicine. 13, 32.

Research output: Contribution to journalArticleAcademicpeer-review

Preserved muscle oxidative metabolic phenotype in newly diagnosed non-small cell lung cancer cachexia

Op den Kamp, C. M., Gosker, H. R., Lagarde, S., Tan, D. Y., Snepvangers, F. J., Dingemans, A-M. C., Langen, R. C. J. & Schols, A. M. W. J., Jun 2015, In : Journal of cachexia, sarcopenia and muscle. 6, 2, p. 164-173

Research output: Contribution to journalArticleAcademicpeer-review

Risk factors for mortality in patients with pulmonary infections with non-tuberculous mycobacteria: A retrospective cohort study

Gommans, E. P. A. T., Even, P., Linssen, C. F. M., van Dessel, H., van Haren, E., de Vries, G. J., Dingemans, A. M. C., Kotz, D. & Rohde, G. G. U., 1 Jan 2015, In : Respiratory Medicine. 109, 1, p. 137-145 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Robotic thymectomy in patients with myasthenia gravis: neurological and surgical outcomes

Keijzers, M., de Baets, M., Hochstenbag, M., Abdul-Hamid, M., zur Hausen, A., van der Linden, M., Kuks, J., Verschuuren, J., Kessels, F., Dingemans, A-M. C. & Maessen, J., Jul 2015, In : European Journal of Cardio-Thoracic Surgery. 48, 1, p. 40-45

Research output: Contribution to journalArticleAcademicpeer-review

Single organ metastatic disease and local disease status, prognostic factors for overall survival in stage IV non-small cell lung cancer: Results from a population-based study

Hendriks, L. E., Derks, J. L., Postmus, P. E., Damhuis, R. A., Houben, R. M. A., Troost, E. G. C., Hochstenbag, M. M., Smit, E. F. & Dingemans, A. -M. C., Nov 2015, In : European Journal of Cancer. 51, 17, p. 2534-2544

Research output: Contribution to journalArticleAcademicpeer-review

Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

Chang, J. Y., Senan, S., Paul, M. A., Mehran, R. J., Louie, A. V., Balter, P., Groen, H. J. M., McRae, S. E., Widder, J., Feng, L., van den Borne, B. E. E. M., Munsell, M. F., Hurkmans, C., Berry, D. A., van Werkhoven, E., Kresl, J. J., Dingemans, A-M., Dawood, O., Haasbeek, C. J. A., Carpenter, L. S. & 5 others, De Jaeger, K., Komaki, R., Slotman, B. J., Smit, E. F. & Roth, J. A., Jun 2015, In : Lancet oncology. 16, 6, p. 630-637

Research output: Contribution to journalArticleAcademicpeer-review

Treatment and survival of patients with EGFR-mutated non-small cell lung cancer and leptomeningeal metastasis: A retrospective cohort analysis

Kuiper, J. L., Hendriks, L. E., van der Wekken, A. J., de Langen, A. J., Bahce, I., Thunnissen, E., Heideman, D. A. M., Berk, Y., Buijs, E. J. M., Speel, E-J. M., Krouwels, F. H., Smit, H. J. M., Groen, H. J. M., Dingemans, A-M. C. & Smit, E. F., Sep 2015, In : Lung Cancer. 89, 3, p. 255-261

Research output: Contribution to journalArticleAcademicpeer-review

2014

8 Years' experience with robotic thymectomy for thymomas

Keijzers, M., Dingemans, A-M. C., Blaauwgeers, H., van Suylen, R. J., Hochstenbag, M., van Garsse, L., Accord, R., de Baets, M. & Maessen, J., Apr 2014, In : Surgical endoscopy and other interventional techniques. 28, 4, p. 1202-1208

Research output: Contribution to journalArticleAcademicpeer-review

A Phase I Study of Concurrent Individualized, Isotoxic Accelerated Radiotherapy and Cisplatin-Vinorelbine-Cetuximab in Patients With Stage III Non-Small-Cell Lung Cancer

Dingemans, A-M. C., Bootsma, G., van Baardwijk, A., Reymen, B., Wanders, R., Brans, B., Das, M., Hochstenbag, M., van Belle, A., Houben, R., Lambin, P. & de Ruysscher, D., May 2014, In : Journal of Thoracic Oncology. 9, 5, p. 710-716

Research output: Contribution to journalArticleAcademicpeer-review

A prospective study comparing the predictions of doctors versus models for treatment outcome of lung cancer patients: A step toward individualized care and shared decision making

Oberije, C., Nalbantov, G., Dekker, A., Boersma, L., Borger, J., Reymen, B., van Baardwijk, A., Wanders, R., De Ruysscher, D., Steyerberg, E., Dingemans, A-M. & Lambin, P., Jul 2014, In : Radiotherapy and Oncology. 112, 1, p. 37-43

Research output: Contribution to journalArticleAcademicpeer-review

Early body weight loss during concurrent chemo-radiotherapy for non-small cell lung cancer

Op den Kamp, C. M. H., de Ruysscher, D. K. M., van den Heuvel, M., Elferink, M., Houben, R. M. A., Oberije, C. J. G., Bootsma, G. P., Geraedts, W. H., Pitz, C. C. M., Langen, R. C., Wouters, E. F. M., Schols, A. M. W. J. & Dingemans, A. M. C., 1 Jan 2014, In : Journal of cachexia, sarcopenia and muscle. 5, 2, p. 127-137

Research output: Contribution to journalArticleAcademicpeer-review

EGFR mutated non-small cell lung cancer patients: More prone to development of bone and brain metastases?

Hendriks, L. E. L., Smit, E. F., Vosse, B. A. H., Mellema, W. W., Heideman, D. A. M., Bootsma, G. P., Westenend, M., Pitz, C., de Vries, G. J., Houben, R., Grunberg, K., Bendek, M., Speel, E-J. M. & Dingemans, A-M. C., Apr 2014, In : Lung Cancer. 84, 1, p. 86-91

Research output: Contribution to journalArticleAcademicpeer-review

Galectin Expression Profiling Identifies Galectin-1 and Galectin-9 Delta 5 as Prognostic Factors in Stage I/II Non-Small Cell Lung Cancer

Schulkens, I. A., Heusschen, R., van den Boogaart, V., van Suylen, R-J., Dingemans, A-M. C., Griffioen, A. W. & Thijssen, V. L., 26 Sep 2014, In : PLOS ONE. 9, 9, e107988.

Research output: Contribution to journalArticleAcademicpeer-review

Interobserver Variability for the WHO Classification of Pulmonary Carcinoids

Swarts, D. R. A., van Suylen, R-J., den Bakker, M. A., van Oosterhout, M. F. M., Thunnissen, F. B. J. M., Volante, M., Dingemans, A-M. C., Scheltinga, M. R. M., Bootsma, G. P., Pouwels, H. M. M., van den Borne, B. E. E. M., Ramaekers, F. C. S. & Speel, E-J. M., Oct 2014, In : American Journal of Surgical Pathology. 38, 10, p. 1429-1436

Research output: Contribution to journalArticleAcademicpeer-review

Long-term survival of stage T4N0-1 and single station IIIA-N2 NSCLC patients treated with definitive chemo-radiotherapy using individualised isotoxic accelerated radiotherapy (INDAR)

Reymen, B., van Baardwijk, A., Wanders, R., Borger, J., Dingemans, A-M. C., Bootsma, G., Pitz, C., Lunde, R., Geraedts, W., Lambin, P. & De Ruysscher, D., Mar 2014, In : Radiotherapy and Oncology. 110, 3, p. 482-487

Research output: Contribution to journalArticleAcademicpeer-review

Lungscape: Resected Non-Small-Cell Lung Cancer Outcome by Clinical and Pathological Parameters

Peters, S., Weder, W., Dafni, U., Kerr, K. M., Bubendorf, L., Meldgaard, P., O'Byrne, K. J., Wrona, A., Vansteenkiste, J., Felip, E., Marchetti, A., Savic, S., Lu, S., Smit, E., Dingemans, A-M., Blackhall, F. H., Baas, P., Camps, C., Rosell, R. & Stahel, R. A., Nov 2014, In : Journal of Thoracic Oncology. 9, 11, p. 1675-1684

Research output: Contribution to journalArticleAcademicpeer-review

Patient selection for whole brain radiotherapy (WBRT) in a large lung cancer cohort: Impact of a new Dutch guideline on brain metastases

Hendriks, L. E. L., Troost, E. G. C., Steward, A., Bootsma, G. P., De Jaeger, K., van den Borne, B. E. E. M. & Dingemans, A-M. C., Jul 2014, In : Acta Oncologica. 53, 7, p. 945-951

Research output: Contribution to journalArticleAcademicpeer-review

Phase II drugs that are currently in development for the treatment of cachexia

Dingemans, A-M. C., de Vos-Geelen, J., Langen, R. & Schols, A. M. W., Dec 2014, In : Expert Opinion on Investigational Drugs. 23, 12, p. 1655-1669

Research output: Contribution to journalArticleAcademicpeer-review

What to choose as radical local treatment for lung metastases from cob-rectal cancer: Surgery or radiofrequency ablation?

Schlijper, R. C. J., Grutters, J. P. C., Houben, R., Dingemans, A-M. C., Wildberger, J. E., Van Raemdonck, D., Van Cutsem, E., Haustermans, K., Lammering, G., Lambin, P. & De Ruysscher, D., Feb 2014, In : Cancer Treatment Reviews. 40, 1, p. 60-67

Research output: Contribution to journalArticleAcademicpeer-review

2013

A Phase II Study of Sorafenib in Patients with Platinum-Pretreated, Advanced (Stage IIIb or IV) Non-Small Cell Lung Cancer with a KRAS Mutation

Dingemans, A-M. C., Mellema, W. W., Groen, H. J. M., van Wijk, A., Burgers, S. A., Kunst, P. W. A., Thunnissen, E., Heideman, D. A. M. & Smit, E. F., 1 Feb 2013, In : Clinical Cancer Research. 19, 3, p. 743-751

Research output: Contribution to journalArticleAcademicpeer-review

A randomized phase II study comparing erlotinib versus erlotinib with alternating chemotherapy in relapsed non-small-cell lung cancer patients: the NVALT-10 study(dagger)

Aerts, J. G., Codrington, H., Lankheet, N. A. G., Burgers, S., Biesma, B., Dingemans, A. -M. C., Vincent, A. D., Dalesio, O., Groen, H. J. M. & Smit, E. F., Nov 2013, In : Annals of Oncology. 24, 11, p. 2860-2865

Research output: Contribution to journalArticleAcademicpeer-review

Arginase-1 mRNA expression correlates with myeloid-derived suppressor cell levels in peripheral blood of NSCLC patients

Heuvers, M. E., Muskens, F., Bezemer, K., Lambers, M., Dingemans, A-M. C., Groen, H. J. M., Smit, E. F., Hoogsteden, H. C., Hegmans, J. P. J. J. & Aerts, J. G. J. V., Sep 2013, In : Lung Cancer. 81, 3, p. 468-474

Research output: Contribution to journalArticleAcademicpeer-review

Cardiac comorbidity is an independent risk factor for radiation-induced lung toxicity in lung cancer patients

Nalbantov, G., Kietselaer, B., Vandecasteele, K., Oberije, C., Berbee, M., Troost, E., Dingemans, A. M., Baardwijk, A. V., Smits, K., Dekker, A., Bussink, J., Ruysscher, D. D., Lievens, Y. & Lambin, P., Oct 2013, In : Radiotherapy and Oncology. 109, 1, p. 100-106 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

CD44 and OTP Are Strong Prognostic Markers for Pulmonary Carcinoids

Swarts, D. R. A., Henfling, M. E. R., Van Neste, L., van Suylen, R-J., Dingemans, A-M. C., Dinjens, W. N. M., Haesevoets, A., Rudelius, M., Thunnissen, E., Volante, M., Van Criekinge, W., van Engeland, M., Ramaekers, F. C. S. & Speel, E-J. M., 15 Apr 2013, In : Clinical Cancer Research. 19, 8, p. 2197-2207

Research output: Contribution to journalArticleAcademicpeer-review

KRAS Mutations in Advanced Nonsquamous Non-Small-Cell Lung Cancer Patients Treated with First-Line Platinum-Based Chemotherapy Have No Predictive Value

Mellema, W. W., Dingemans, A-M. C., Thunnissen, E., Snijders, P. J. F., Derks, J., Heideman, D. A. M., Van Suylen, R. & Smit, E. F., Sep 2013, In : Journal of Thoracic Oncology. 8, 9, p. 1190-1195

Research output: Contribution to journalArticleAcademicpeer-review

Nuclear transcription factor κ B activation and protein turnover adaptations in skeletal muscle of patients with progressive stages of lung cancer cachexia.

Op den Kamp, C. M. H., Langen, R. C. J., Snepvangers, F. J., de Theije, C. C., Schellekens, J. M., Laugs, F., Dingemans, A. M. & Schols, A. M. W. J., Sep 2013, In : American Journal of Clinical Nutrition. 98, 3, p. 738-748 11 p.

Research output: Contribution to journalArticleAcademicpeer-review