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Research Output 2002 2019

2019

Redox Imbalance in Idiopathic Pulmonary Fibrosis: A Role for Oxidant Cross-Talk Between NADPH Oxidase Enzymes and Mitochondria

Veith, C., Boots, A. W., Idris, M., van Schooten, F-J. & van der Vliet, A., 10 Nov 2019, In : Antioxidants & Redox Signaling. 31, 14, p. 1092-1115 24 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Cigarette Filter Ventilation and Smoking Protocol Influence Aldehyde Smoke Yields

Pauwels, C. G. G. M., Klerx, W. N. M., Pennings, J. L. A., Boots, A. W., van Schooten, F. J., Opperhuizen, A. & Talhout, R., 18 Jun 2018, In : Chemical Research in Toxicology. 31, 6, p. 462-471 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exposure to genotoxic compounds alters in vitro cellular VOC excretion

Fijten, R. R. R., Smolinska, A., Shi, Q., Pachen, D. M., Dallinga, J. W., Boots, A. W. & van Schooten, F. J., Apr 2018, In : Journal of Breath Research. 12, 2, 8 p., 027101.

Research output: Contribution to journalArticleAcademicpeer-review

The necessity of external validation in exhaled breath research: a case study of sarcoidosis

Fijten, R. R. R., Smolinska, A., Drent, M., Dallinga, J. W., Mostard, R., Pachen, D. M., van Schooten, F. J. & Boots, A. W., 1 Jan 2018, In : Journal of Breath Research. 12, 1, 11 p., 016004.

Research output: Contribution to journalArticleAcademicpeer-review

2017

A European Respiratory Society technical standard: exhaled biomarkers in lung disease

Horvath, I., Barnes, P. J., Loukides, S., Sterk, P. J., Hogman, M., Olin, A-C., Amann, A., Antus, B., Baraldi, E., Bikov, A., Boots, A. W., Bos, L. D., Brinkman, P., Bucca, C., Carpagnano, G. E., Corradi, M., Cristescu, S., de Jongste, J. C., Dinh-Xuan, A-T., Dompeling, E. & 22 others, Fens, N., Fowler, S., Hohlfeld, J. M., Holz, O., Jobsis, Q., Van De Kant, K., Knobel, H. H., Kostikas, K., Lehtimaki, L., Lundberg, J., Montuschi, P., Van Muylem, A., Pennazza, G., Reinhold, P., Ricciardolo, F. L. M., Rosias, P., Santonico, M., van der Schee, M. P., van Schooten, F-J., Spanevello, A., Tonia, T. & Vink, T. J., Apr 2017, In : European Respiratory Journal. 49, 4, 26 p., 1600965.

Research output: Contribution to journalArticleAcademicpeer-review

Diesel engine exhaust accelerates plaque formation in a mouse model of Alzheimer's disease

Hullmann, M., Albrecht, C., van Berlo, D., Gerlofs-Nijland, M. E., Wahle, T., Boots, A. W., Krutmann, J., Cassee, F. R., Bayer, T. A. & Schins, R. P. F., 30 Aug 2017, In : Particle and Fibre Toxicology. 14 p., 35.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells

Shi, Q., Boots, A. W., Maas, L., Veith, C., van Kuijk, K., Haenen, G. R., Godschalk, R. W. & Van Schooten, F. J., 15 Apr 2017, In : Toxicology. 381, p. 64-74 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The disturbed redox-balance in pulmonary fibrosis is modulated by the plant flavonoid quercetin

Veith, C., Drent, M., Bast, A., van Schooten, F. J. & Boots, A. W., 1 Dec 2017, In : Toxicology and Applied Pharmacology. 336, p. 40-48 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2016

LSC 2016: from system approaches in lung disease to getting the job you want

Boots, A., Flood, E., Kahn, N., Hardavella, G., Bikov, A., Aamli, A. & Skoczynski, S., 1 Jun 2016, In : Breathe. 12, 2, p. 169-173

Research output: Contribution to journalArticleAcademicpeer-review

Opportunities for ERS junior members in 2016 Juniors' voice

Boots, A., Flood, E. & Skoczynski, S., 1 Mar 2016, In : Breathe. 12, 1, p. 69-71

Research output: Contribution to journalArticleAcademicpeer-review

2015
10 Citations (Scopus)

Analysis of volatile organic compounds in exhaled breath to diagnose ventilator-associated pneumonia

Schnabel, R., Fijten, R., Smolinska, A., Dallinga, J., Boumans, M. L., Stobberingh, E., Boots, A., Roekaerts, P., Bergmans, D. & van Schooten, F. J., 26 Nov 2015, In : Scientific Reports. 5, 10 p., 17179.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Dynamic collection and analysis of volatile organic compounds from the headspace of cell cultures

Baranska, A. L., Smolinska, A., Boots, A. W., Dallinga, J. W. & van Schooten, F. J., 1 Jan 2015, In : Journal of Breath Research. 9, 4, 047102.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Exhaled Molecular Fingerprinting in Diagnosis and Monitoring: Validating Volatile Promises

Boots, A. W., Bos, L. D., van der Schee, M. P., van Schooten, F. J. & Sterk, P. J., 1 Jan 2015, In : Trends in Molecular Medicine. 21, 10, p. 633-644

Research output: Contribution to journalArticleAcademicpeer-review

2014
20 Citations (Scopus)

Apoptotic, inflammatory, and fibrogenic effects of two different types of multi-walled carbon nanotubes in mouse lung

van Berlo, D., Wilhelmi, V., Boots, A. W., Hullmann, M., Kuhlbusch, T. A., Bast, A., Schins, R. P. & Albrecht, C., Sep 2014, In : Archives of Toxicology. 88, 9, p. 1725-1737 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

Identification of microorganisms based on headspace analysis of volatile organic compounds by gas chromatography-mass spectrometry

Boots, A. W., Smolinska, A., van Berkel, J. J. B. N., Fijten, R. R. R., Stobberingh, E. E., Boumans, M. L. L., Moonen, E. J., Wouters, E. F. M., Dallinga, J. W. & van Schooten, F. J., 1 Jan 2014, In : Journal of Breath Research. 8, 2, 027106.

Research output: Contribution to journalArticleAcademicpeer-review

Volatile organic compounds as exhaled biomarkers of inflammation and oxidative stress in respiratory diseases.

van Schooten, F. J., Boots, A. W., Smolinska, A. M. & Dallinga, J. W., 1 Jan 2014, Oxidative stress in applied basic research and clinical practice:. Ganguly, N. K., Jindal, S. K., Biswal, S., Barnes, P. J. & Pawankar, R. (eds.). New York: Springer, p. 67-84

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

2013
26 Citations (Scopus)

Characterization of the inflammatory and metabolic profile of adipose tissue in a mouse model of chronic hypoxia.

van den Borst, B., Schols, A. M. W. J., de Theije, C. C., Boots, A. W., Köhler, S. E., Goossens, G. H. & Gosker, H. R., Jun 2013, In : Journal of Applied Physiology. 114, 11, p. 1619-1628 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)

Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells.

Gerloff, K., Pereira, D. I., Faria, N., Boots, A. W., Kolling, J., Forster, I., Albrecht, C., Powell, J. J. & Schins, R. P., 1 Jan 2013, In : Nanotoxicology. 7, 4, p. 353-366

Research output: Contribution to journalArticleAcademicpeer-review

2012
3 Citations (Scopus)

Cat litter is a possible trigger for sarcoidosis

Drent, M., Wijnen, P. A. H. M., Boots, A. W. & Bast, A., 1 Jan 2012, In : European Respiratory Journal. 39, 1, p. 221-222 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

70 Citations (Scopus)

Distinctive toxicity of tio2 rutile/anatase mixed phase nanoparticles on caco-2 cells

Gerloff, K., Fenoglio, I., Carella, E., Kolling, J., Albrecht, C., Boots, A. W., Forster, I. & Schins, R. P., Mar 2012, In : Chemical Research in Toxicology. 25, 3, p. 646-655 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells

Boots, A. W., Gerloff, K., Bartholomé, R., van Berlo, D., Ledermann, K., Haenen, G. R. M. M., Bast, A., van Schooten, F. J., Albrecht, C. & Schins, R. P., Jul 2012, In : Biochimica et Biophysica Acta-Molecular Cell Research. 1823, 7, p. 1151-1162 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

87 Citations (Scopus)

The versatile use of exhaled volatile organic compounds in human health and disease

Boots, A. W., van Berkel, J. J. B. N., Dallinga, J. W., Smolinska, A. M., Wouters, E. F. M. & van Schooten, F. J., Jun 2012, In : Journal of Breath Research. 6, 2, 21 p., 027108.

Research output: Contribution to journalArticleAcademicpeer-review

2011
6 Citations (Scopus)

Letter to the editor

Gerloff, K., Albrecht, C., Boots, A. W., Forster, I. & Schins, R. P., Jun 2011, In : Nanotoxicology. 5, 2, p. 282-283 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

20 Citations (Scopus)

Oxidative stress and DNA damage responses in rat and mouse lung to inhaled carbon nanoparticles

Wessels, A., van Berlo, D., Boots, A. W., Gerloff, K., Scherbart, A. M., Cassee, F. R., Gerlofs Nijland, M. E., van Schooten, F. J., Albrecht, C. & Schins, R. P., 1 Jan 2011, In : Nanotoxicology. 5, 1, p. 66-78 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

54 Citations (Scopus)

Quercetin reduces markers of oxidative stress and inflammation in sarcoidosis

Boots, A. W., Drent, M., de Boer, V. C., Bast, A. & Haenen, G. R. M. M., 1 Jan 2011, In : Clinical Nutrition. 30, 4, p. 506-512

Research output: Contribution to journalArticleAcademicpeer-review

2010
30 Citations (Scopus)

Erythritol is a sweet antioxidant

den Hartog, G. J., Boots, A. W., Adam Perrot, A., Brouns, F. J. P. H., Verkooijen, I. W., Weseler, A. R., Haenen, G. R. & Bast, A., 1 Jan 2010, In : Nutrition. 26, 4, p. 449-458

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

van Berlo, D., Wessels, A., Boots, A. W., Wilhelmi, V., Scherbart, A. M., Gerloff, K., van Schooten, F. J., Albrecht, C. & Schins, R. P., 1 Jan 2010, In : Free Radical Biology and Medicine. 49, 11, p. 1685-1693

Research output: Contribution to journalArticleAcademicpeer-review

2009
38 Citations (Scopus)

Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants

Boots, A. W., Drent, M., Swennen, E. L., Moonen, H. J., Bast, A. & Haenen, G. R., 1 Jan 2009, In : Respiratory Medicine. 103, 3, p. 364-372

Research output: Contribution to journalArticleAcademicpeer-review

65 Citations (Scopus)

ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli.

Boots, A. W., Hristova-Dijkstra, M. J., Kasahara, D. I., Haenen, G. R., Bast, A. & van der Vliet, A., 1 Jan 2009, In : Journal of Biological Chemistry. 284, 26, p. 17858-17867

Research output: Contribution to journalArticleAcademicpeer-review

2008
671 Citations (Scopus)

Health effects of quercetin: from antioxidant to nutraceutical.

Boots, A. W., Haenen, G. R. & Bast, A., 1 Jan 2008, In : European Journal of Pharmacology. 585, 2-3, p. 325-337

Research output: Contribution to journalArticleAcademicpeer-review

113 Citations (Scopus)

In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers

Boots, A., Wilms, L. C., Swennen, E. L., Kleinjans, J. C., Bast, A. & Haenen, G. R., 1 Jan 2008, In : Nutrition. 24, 7-8, p. 703-10

Research output: Contribution to journalArticleAcademicpeer-review

2007
48 Citations (Scopus)

Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers

Wilms, L. C., Boots, A. W., de Boer, V. C., Maas, L. M., Pachen, D. M., Gottschalk, R. W., Ketelslegers, H., Godschalk, R. W., Haenen, G. R., van Schooten, F. J. & Kleinjans, J. C., 1 Jan 2007, In : Carcinogenesis. 28, 8, p. 1800-1806

Research output: Contribution to journalArticleAcademicpeer-review

Inflammatory and oxidative stress status in NSCLC patients and the ex vivo immunomodulatory effects of ATP in stimulated blood: a pilot study Maastricht

Swennen, E. L., van den Broek, S. A. W., Boots, A. W., Arts, I., van den Brandt, P. A., Bast, A. & Dagnelie, P. C., 1 Jan 2007, WEON 2007.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

129 Citations (Scopus)

The quercetin paradox

Boots, A. W., Li, H., Schins, R. P., Heemskerk, J. W., Bast, A. & Haenen, G. R., 1 Jan 2007, In : Toxicology and Applied Pharmacology. 222, 1, p. 89-96

Research output: Contribution to journalArticleAcademicpeer-review

2006
808 Downloads (Pure)

Health effects of quercetin : from mechanism to nutraceutical

Boots, A. W., 1 Jan 2006, Maastricht: Universitaire Pers Maastricht. 215 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
2005
12 Citations (Scopus)

No role of DT-diaphorase (NQO1) in the protection against oxidized quercetin

Boots, A. W., Bast, A. & Haenen, G. R., 1 Jan 2005, In : Febs Letters. 579, 3, p. 677-682

Research output: Contribution to journalArticleAcademicpeer-review

118 Citations (Scopus)
37 Citations (Scopus)

The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity

Boots, A. W., Balk, J. M., Bast, A. & Haenen, G. R., 1 Jan 2005, In : Biochemical and Biophysical Research Communications. 338, 2, p. 923-929

Research output: Contribution to journalArticleAcademicpeer-review

2004

Myeloperoxidase (MPO)-463G -> A reduces MPO activity and DNA adduct levels in bronchoalveolar lavages of smokers

van Schooten, F. J., Boots, A. W., Knaapen, A. M., Godschalk, R. W., Maas, L. M., Borm, P. J. A., Drent, M. & Jacobs, J. A., 1 Jan 2004, In : Cancer Epidemiology Biomarkers & Prevention. 13, 5, p. 828-833

Research output: Contribution to journalArticleAcademicpeer-review

2003
9 Citations (Scopus)

Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin

den Hartog, G. J. M., Boots, A. W., Haenen, G. R. M. M., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : Toxicology in Vitro. 17, 2, p. 165-167 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

85 Citations (Scopus)

Oxidant metabolism in chronic obstructive pulmonary disease

Boots, A. W., Haenen, G. R. M. M. & Bast, A., 1 Jan 2003, In : European Respiratory Journal. 22, suppl 46, p. 14S-27S 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

94 Citations (Scopus)

Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation

Boots, A. W., Knubben, N., Haenen, G. R. M. M. & Bast, A., 1 Jan 2003, In : Biochemical and Biophysical Research Communications. 308, 3, p. 560-565 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

2002
36 Citations (Scopus)