If you made any changes in Pure these will be visible here soon.

Research Output

2004

The extraordinary antioxidant activity of vitamin E phosphate

Rezk, B. M., Haenen, G. R., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2004, In : Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids. 1683, 1-3, p. 16-21

Research output: Contribution to journalArticleAcademicpeer-review

The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids

Michels, G., Haenen, G. R., Wätjen, W., Rietjens, S. J. & Bast, A., 1 Jan 2004, In : Toxicology Letters. 151, 1, p. 105-111

Research output: Contribution to journalArticleAcademicpeer-review

Voedingssupplementen en vitamines

Bast, A. & van den Berg, H., 1 Jan 2004, Therapie Informatorium. Houten: Bohn, Stafleu en Van Loghum

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

2003

A comparative study between catalase gene therapy and the cardioprotector monohydroxyethylrutoside (MonoHER) in protecting against doxorubicin-induced cardiotoxicity in vitro

Abou el Hassan, M. A., Rabelink, M. J., van der Vijgh, W. J. F., Bast, A. & Hoeben, R. C., 1 Jan 2003, In : British Journal of Cancer. 89, 11, p. 2140-2146 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A critical appraisal of the use of the antioxidant capacity (TEAC) assay in defining optimal structures

Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M. & Bast, A., 1 Jan 2003, In : Food Chemistry. 80, p. 409-414 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bioavailability and pharmacokinetics of the cardioprotecting flavonoid 7-monohydroxyethylrutoside in mice

Abou el Hassan, M. A., Kedde, M., Zwiers, U. T., Tourn, E., Haenen, G. R. M. M., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2003, In : Cancer Chemotherapy and Pharmacology. 52, 5, p. 371-376 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cardiac failure associated with G6PD deficiency

Drent, M., Gorgels, A. P. M. & Bast, A., 1 Jan 2003, In : Circulation Research. 93, e75.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Effect of vitamin E on glutathione-dependent enzymes

van Haaften, R. I. M., Haenen, G. R. M. M., Evelo, C. T. A. & Bast, A., 1 Jan 2003, In : Drug Metabolism Reviews. 35, 2-3, p. 215-253 36 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inhibition of various glutathione S-transferase isoenzymes by RRR-alpha-tocopherol

van Haaften, R. I. M., Haenen, G. R. M. M., van Bladeren, P. J., Bogaards, J. J., Evelo, C. T. A. & Bast, A., 1 Jan 2003, In : Toxicology in Vitro. 17, 3, p. 245-251 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lack of inhibition of endothelial nitric oxide synthase in the isolated rat aorta by doxorubicin

den Hartog, G. J. M., Boots, A. W., Haenen, G. R. M. M., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : Toxicology in Vitro. 17, 2, p. 165-167 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipoic acid: a multifunctional antioxidant

Bast, A. & Haenen, G. R. M. M., 1 Jan 2003, In : Biofactors. 17, 1-4, p. 207-213 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Longfibrose: stand van zaken

Drent, M. & Bast, A., 1 Jan 2003, In : Modern Medicine. 8, p. 44-50 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

New method to study oxidative damage and antioxidants in the human small bowel: effects of iron application

Troost, F. J. J., Saris, W. H. M., Haenen, G. R. M. M., Bast, A. & Brummer, R. J. M., 1 Jan 2003, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 285, 2, p. G354-G359 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
166 Downloads (Pure)

Oxidant metabolism in chronic obstructive pulmonary disease

Boots, A. W., Haenen, G. R. M. M. & Bast, A., 1 Jan 2003, In : European Respiratory Journal. 22, suppl 46, p. 14S-27S 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Oxidative stress in patients with active HCV infection compared to healthy volunteers

de Kort, J., Fischer, M., Haenen, G. R. M. M., Bast, A. & Koek, G. H., 1 Jan 2003, In : Journal of Hepatology. 38, p. 374

Research output: Contribution to journalArticleAcademicpeer-review

Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation

Boots, A. W., Knubben, N., Haenen, G. R. M. M. & Bast, A., 1 Jan 2003, In : Biochemical and Biophysical Research Communications. 308, 3, p. 560-565 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Role of superoxide anion on basal and stimulated nitric oxide activity in neonatal piglet pulmonary vessels

Villamor, E., Kessels, C. G. A., Fischer, M. A. J. G., Bast, A., de Mey, J. G. R. & Blanco, C. E., 1 Jan 2003, In : Pediatric Research. 54, 3, p. 372-381 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Superoxide dismutase: the balance between prevention and induction of oxidative damage

den Hartog, G. J. M., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : Chemico-Biological Interactions. 145, 1, p. 33-39 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients

Hageman, G. J., Larik, I., Pennings, H. J., Haenen, G. R. M. M., Wouters, E. F. M. & Bast, A., 1 Jan 2003, In : Free Radical Biology and Medicine. 35, 2, p. 140-148 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore

Rezk, B. M., Haenen, G. R. M. M., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : Febs Letters. 555, 3, p. 601-605 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The cardioprotector monoHER does not interfere with the pharmacokinetics or the metabolism of the cardiotoxic agent doxorubicin in mice

Abou el Hassan, M. A., Kedde, M. A., Zwiers, U. T., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2003, In : Cancer Chemotherapy and Pharmacology. 51, 4, p. 306-310 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitro

Abou el Hassan, M. A., Verheul, H. M., Jorna, A. S., Schalkwijk, C. G., van Bezu, J., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2003, In : British Journal of Cancer. 89, 2, p. 357-362 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells

Abou el Hassan, M. A., Heijn, M., Rabelink, M. J., van der Vijgh, W. J. F., Bast, A. & Hoeben, R. C., 1 Jan 2003, In : Cancer Gene Therapy. 10, 4, p. 270-277 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The risk of eating: the toxicity of natural versus man-made chemicals

Bast, A., 1 Jan 2003, Chemistry of crop protection. Voss, G. & Ramos, G. (eds.). Wiley-VCH Verlag, p. 63-68

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Using a correction factor to correct for overreporting in a food-frequency questionnaire does not improve biomarker-assessed validity of estimates for fruit and vegetable consumption

Bogers, R. P., Dagnelie, P. C., Westerterp, K. R., Kester, A. D. M., van Klaveren, J. D., Bast, A. & van den Brandt, P. A., 1 Jan 2003, In : Journal of Nutrition. 133, 4, p. 1213-1219 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
192 Downloads (Pure)
2002

Bioavailability and metabolism

Stahl, W., van den Berg, H., Arthur, J., Bast, A., Dainty, J., Faulks, R. M., Gartner, C., Haenen, G. R. M. M. & et, A., 1 Jan 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 39-100 61 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biomarkers

Griffiths, H. R., Moller, L., Bartosz, G., Bast, A., Bertoni-Freddari, C., Collins, A., Cooke, M., Coolen, S., Haenen, G. R. M. M., Hoberg, A. M., Loft, S., Lun, J., Olinski, R., Parry, J., Pompella, A., Poulsen, H. & Verhagen, H., 1 Jan 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 101-108 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Botanical health products, positioning and requirements for effective and safe use

Bast, A., Chandler, R. F., Choy, P. C., Delmulle, L. M., Gruenwald, J., Halkes, S. B. A., Keller, K., Koeman, J. H., Peters, P., Przyrembel, H., de Ree, E. M., Renwick, A. G. & Vermeer, I. T. M., 1 Jan 2002, In : Environmental Toxicology and Pharmacology. 12, p. 195-211 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Decreased redox state in red blood cells from patients with sarcoidosis

Rothkrantz-Kos, S., Drent, M., Vuil, H., de Boer, M., Bast, A., Wouters, E. F. M., Roos, D. & van Dieijen-Visser, M. P., 1 Jan 2002, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 19, 2, p. 114-120 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers

van Schooten, F. J., Besarati Nia, A., de Flora, S., D'Agostini, F., Izzotti, A., Camoirano, A., Balm, A. J. M., Dallinga, J. W., Bast, A., Haenen, G. R. M. M. & et, A., 1 Jan 2002, In : Cancer Epidemiology Biomarkers & Prevention. 11, 2, p. 167-175 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of HOCI scavenging by sulfurcontaining compounds: antioxidant activity of glutathione disulfide?

den Hartog, G. J., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2002, In : Biological Chemistry. 383, p. 709-713

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of HOCl scavenging by sulfur-containing compounds: antioxidant activity of glutathione disulfide?

den Hartog, G. J. M., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2002, In : Biological Chemistry. 383, 3-4, p. 709-713 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Exercise-induced oxidative stress in older adults as a function of habitual activity level

Meijer, E. P., Goris, A. H. C., van Dongen, J. L. J., Bast, A. & Westerterp, K. R., 1 Jan 2002, In : Journal of the American Geriatrics Society. 50, 2, p. 349-353 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hypochlorous acid is a potent inhibitor of acetylcholinesterase

den Hartog, G. J. M., Vegt, E., van der Vijgh, W. J. F., Haenen, G. R. M. M. & Bast, A., 1 Jan 2002, In : Toxicology and Applied Pharmacology. 181, 3, p. 228-232 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interactions between flavonoids and proteins: effect on the total antioxidant capacity

Arts, M. J. T. J., Haenen, G. R. M. M., Wilms, L. C., Beetstra, S., Beerens - Heijnen, C. G. M., Voss, H. P. & Bast, A., 1 Jan 2002, In : Journal of Agricultural and Food Chemistry. 50, 5, p. 1184-1187 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipoic acid: a multifunctional antioxidant

Bast, A. & Haenen, G. R. M. M., 1 Jan 2002, Thiol metabolism and redix regulation of cellular functions. Pompella, A., Banhegyi, G. & Wellma-Rousseau, M. (eds.). Amsterdam/Berlin/Oxford/Tokyo/Washington DC: IOS Press, p. 230-237

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Oxidative stress in patients with active HCV infection

de Kort, J., Haenen, G. R. M. M., Bast, A. & Koek, G. H., 1 Jan 2002, In : Hepatology. 36, 4, p. 743

Research output: Contribution to journalArticleAcademicpeer-review

Protection of flavonoids against lipid peroxidation: the structure activity relationship revisited

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Oostveen, R. M., Stalpers, E. M. & Bast, A., 1 Jan 2002, In : Free Radical Research. 36, 5, p. 575-581 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids

Rezk, B. M., Haenen, G. R. M. M., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2002, In : Biochemical and Biophysical Research Communications. 295, 1, p. 9-13 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

The effect of the trolox equivalent antioxidant capacity (TEAC) in plasma on the formation of 4-aminobiphenylhaemoglobin adducts in smokers

Dallinga, J. W., Haenen, G. R. M. M., Bast, A. & van Schooten, F. J., 1 Jan 2002, In : Biomarkers. 7, 4, p. 291-298 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The toxicity of antioxidants and their metabolites

Bast, A. & Haenen, G. R. M. M., 1 Jan 2002, In : Environmental Toxicology and Pharmacology. 11, p. 251-258 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

The use of vitamin supplements in self-medication

Haenen, G. R. M. M. & Bast, A., 1 Jan 2002, In : Therapie. 57, 2, p. 119-122 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tocotrienols inhibit human glutathione S-transferase P1-1

van Haaften, R. I. M., Haenen, G. R. M. M., Evelo, C. T. A. & Bast, A., 1 Jan 2002, In : Iubmb Life. 54, 2, p. 81-84 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001

alpha-Tocopherol inhibits human glutathione S-transferase pi.

van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Biochemical and Biophysical Research Communications. 280, p. 631-633 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ambient particulate matter induces relaxation of rat aortic rings in vitro.

Knaapen, A. M., den Hartog, G. J. M., Bast, A. & Borm, P. J. A., 1 Jan 2001, In : Human & Experimental Toxicology. 20, 5, p. 259-265 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant supplementation and exercise-induced oxidative stress in the 60-year-old as measured by antipyrine hydroxylates

Meijer, E. P., Goris, A. H. C., Senden, J. M. G., Dongen, J. & Bast, A., 1 Jan 2001, In : British Journal of Nutrition. 86, p. 569-575 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers.

van den Berg, R., van Vliet, T., Broekmans, W. M. R., Cnubben, N. H. P., Vaes, W. H. J., Roza, L., Haenen, G. R. M. M., Bast, A. & van den Berg, H., 1 Jan 2001, In : Journal of Nutrition. 131, p. 1714-1722 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Exercise-induced oxidative stress in older adults as measured by antipyrine oxidation

Meijer, E. P., Coolen, S. A. J., Bast, A. & Westerterp, K. R., 1 Jan 2001, In : Metabolism-Clinical and Experimental. 50, 12, p. 1484-1488 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Exercise training and oxidative stress in the elderly as measured by antipyrine hydroxylation products.

Meijer, E. P., Coolen, S. A. J., Bast, A. & Westerterp, K. R., 1 Jan 2001, In : Free Radical Research. 35, p. 435-443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review