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Research Output

2007

Hormesis in precautionary regulatory culture: Models preferences and the advancement of science

Hanekamp, J. C. & Bast, A., 1 Jan 2007, In : Human & Experimental Toxicology. 26, 11, p. 855-873

Research output: Contribution to journalArticleAcademicpeer-review

Inflammatory and oxidative stress status in NSCLC patients and the ex vivo immunomodulatory effects of ATP in stimulated blood: a pilot study Maastricht

Swennen, E. L., van den Broek, S. A. W., Boots, A. W., Arts, I., van den Brandt, P. A., Bast, A. & Dagnelie, P. C., 1 Jan 2007, WEON 2007.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Liver cirrhosis and vitaminE status.

Koek, G. H., Bast, A. & Driessen, A., 1 Jan 2007, The Encyclopedia of vitamin E.. Preedy, V. R. & Watson, R. R. (eds.). CAB International, p. 773-781

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Local effect of adenosine 5'-triphosphate on indomethacin-induced permeability changes in the human small intestine

Bours, M. J. L., Brummer, R. J. M., Bast, A. & Dagnelie, P. C., 1 Jan 2007, WEON 2007. Maastricht

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Long-term effects of 7-monohydroxyethylrutoside (monoHER) on DOX-induced cardiotoxicity in mice

Bruynzeel, A. M., Vormer Bonne, S., Bast, A., Niessen, H. W. M. & van der Vijgh, W. J., 1 Jan 2007, In : Cancer Chemotherapy and Pharmacology. 60, 4, p. 509-514

Research output: Contribution to journalArticleAcademicpeer-review

New insights into controversies on the antioxidant potential of the olive oil antioxidant hydroxytyrosol

Rietjens, S. J., Bast, A. & Haenen, G. R., 1 Jan 2007, In : Journal of Agricultural and Food Chemistry. 55, 18, p. 7609-7614

Research output: Contribution to journalArticleAcademicpeer-review

New iron chelators in anthracycline-induced cardiotoxicity.

Kaiserova, H., Simunek, T., Sterba, M., den Hartog, G. J., Schroterova, L., Popelova, O., Gersl, V., Kvasnickova, E. & Bast, A., 1 Jan 2007, In : Cardiovascular Toxicology. 7, 2, p. 145-150

Research output: Contribution to journalArticleAcademicpeer-review

New recommended daily allowances: benchmarking healthy European micronutrient regulation. Let governments take care of safety and industry of health.

Hanekamp, J. C. & Bast, A., 1 Jan 2007, In : Environmental Liability. 4, p. 155-162

Research output: Contribution to journalArticleAcademicpeer-review

Oxidative Degradation of Lipids during Mashing

Arts, M. J., Grun, C., Jong, R. L., Voss, H. P., Bast, A., Mueller, M. J. & Haenen, G. R., 1 Jan 2007, In : Journal of Agricultural and Food Chemistry. 55, 17, p. 7010-7014

Research output: Contribution to journalArticleAcademicpeer-review

Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials

Bast, A., Haenen, G. R., Bruynzeel, A. M. & van der Vijgh, W. J., 1 Jan 2007, In : Cardiovascular Toxicology. 7, 2, p. 154-159

Research output: Contribution to journalArticleAcademicpeer-review

Protectors against doxorubicin-induced cardiotoxicity: Flavonoids

Bast, A., Kaiserova, H., den Hartog, G. J., Haenen, G. R. & van der Vijgh, W. J., 1 Jan 2007, In : Cell Biology and Toxicology. 23, 1, p. 39-47

Research output: Contribution to journalArticleAcademicpeer-review

Response to commentators

Hanekamp, J. C. & Bast, A., 1 Jan 2007, In : Human & Experimental Toxicology. 26, 11, p. 875-876

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Review article: The prevalence and clinical relevance of cytochrome P450 polymorphisms.

Wijnen, P. A. H. M., Op den Buisch, R., Drent, M., Kuipers, P. M. J. C., Neefs, C., Bast, A., Bekers, O. & Koek, G. H., 1 Jan 2007, In : Alimentary Pharmacology & Therapeutics. 26, 2, p. 211-219

Research output: Contribution to journalArticleAcademicpeer-review

The effect of monohydroxyethylrutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study

Bruynzeel, A. M., Niessen, H. W. M., Bronzwaer, J. G., van der Hoeven, J. J., Berkhof, J., Bast, A., van der Vijgh, W. J. & van Groeningen, C. J., 1 Jan 2007, In : British Journal of Cancer. 97, 8, p. 1084-1089

Research output: Contribution to journalArticleAcademicpeer-review

The European regulation of food supplements and food fortification. Intended normal use ' The ultimate tool in organising level playing field markets and regulations or how to break the fairy ring around 'other substances'.

Schwitters, B., Achanta, G., van der Vlies, D., Morisset, H., Bast, A. & Hanekamp, J. C., 1 Jan 2007, In : Environmental Law and Management. 19, p. 19-29

Research output: Contribution to journalArticleAcademicpeer-review

The quercetin paradox

Boots, A. W., Li, H., Schins, R. P., Heemskerk, J. W., Bast, A. & Haenen, G. R., 1 Jan 2007, In : Toxicology and Applied Pharmacology. 222, 1, p. 89-96

Research output: Contribution to journalArticleAcademicpeer-review

Voedingssupplementen.

Bast, A. & van den Berg, H., 1 Jan 2007, Diagnose en therapie Jaarboek 2007.. Everdingen, J. J. E. V. & Glerum, J. H. (eds.). Bohn Stafleu van Loghum, p. 1179-1205

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

2006

A phase I study of monohydroxyethylrutoside in healthy volunteers

Willems, A. M., Bruynzeel, A. M., Kedde, M. A., van Groeningen, C. J., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2006, In : Cancer Chemotherapy and Pharmacology. 57, 5, p. 678-684

Research output: Contribution to journalArticleAcademicpeer-review

Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.

Geraets, L., Moonen, H. J., Wouters, E. F., Bast, A. & Hageman, G. J., 1 Jan 2006, In : Biochemical Pharmacology. 72, 7, p. 902-910

Research output: Contribution to journalArticleAcademicpeer-review

Food supplements and fortified foods: the EC's patriarchal precautionary perspectives on public health

Hanekamp, J. C. & Bast, A., 1 Jan 2006, In : Environmental Liability. 5, p. 181-191

Research output: Contribution to journalArticleAcademicpeer-review

Free radicals in exhaled breath condensate in cystic fibrosis and healthy subjects

Rosias, P. P. R., den Hartog, G. J., Robroeks, C. M., Bast, A., Donckerwolcke, R. A., Heynens, J. W., Suykerbuyk, J., Hendriks, H. J., Jöbsis, Q. & Dompeling, E. D., 1 Jan 2006, In : Free Radical Research. 40, 9, p. 901-909

Research output: Contribution to journalArticleAcademicpeer-review

Gene expression in human small intestinal mucosa in vivo is mediated by iron-induced oxidative stress

Troost, F. J., Brummer, R. J., Haenen, G. R., Bast, A., van Haaften, R. I. M., Evelo, C. T. & Saris, W. H., 1 Jan 2006, In : Physiological genomics. 25, 2, p. 242-249

Research output: Contribution to journalArticleAcademicpeer-review

Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin

Kaiserova, H., den Hartog, G. J., Simunek, T., Schroterova, L., Kvasnickova, E. & Bast, A., 1 Jan 2006, In : British Journal of Pharmacology. 149, 7, p. 920-930

Research output: Contribution to journalArticleAcademicpeer-review

Purinergic receptors involved in the immunomodulatory effects of ATP in human blood

Swennen, E. L. R., Bast, A. & Dagnelie, P. C., 1 Jan 2006, In : Biochemical and Biophysical Research Communications. 348, 3, p. 1194-1199

Research output: Contribution to journalArticleAcademicpeer-review

Structure and activity in assessing antioxidant activity in vitro and in vivo. A critical appraisal illustrated with the flavenoids

Haenen, G. R., Arts, M. J. T., Bast, A. & Coleman, M. D., 1 Jan 2006, In : Environmental Toxicology and Pharmacology. 21, p. 191-198

Research output: Contribution to journalArticleAcademicpeer-review

The influence of the time interval between monoHER and doxorubicin administration on the protection against doxorubicin-induced cardiotoxicity in mice

Bruynzeel, A. M., Mul, P. P., Berkhof, J., Bast, A., Niessen, H. W. M. & van der Vijgh, W. J. F., 1 Jan 2006, In : Cancer Chemotherapy and Pharmacology. 58, 5, p. 699-702

Research output: Contribution to journalArticleAcademicpeer-review

Urea as a marker of dilution of nasal secretion in nasal lavage fluid

Puts, E. W. A., Lammerts, L., Bast, A., van Dieijen-Visser, M. P. & Kremer, B., 1 Jan 2006, In : Allergologie. 29, p. 184-193

Research output: Contribution to journalArticleAcademicpeer-review

Voedingssuplementen

Bast, A. & van den Berg, H., 1 Jan 2006, Diagnose en therapie Jaarboek 2006. Everdingen, E. E. V. & Glerum, J. H. (eds.). Bohn Stafleu van Loghum, p. 1147-1172

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

2005

Altered antioxidant status in peripheral skeletal muscle of patients with COPD

Gosker, H. R., Bast, A., Haenen, G. R. M. M., Fischer, M. A. J. G., van der Vusse, G. J., Wouters, E. F. M. & Schols, A. M. W. J., 1 Jan 2005, In : Respiratory Medicine. 99, p. 118-125

Research output: Contribution to journalArticleAcademicpeer-review

Determination of the antioxidant capacity in blood

Fischer, M. A. J. G., Gransier, T. J., Beckers, L. M., Bekers, O., Bast, A. & Haenen, G. R., 1 Jan 2005, In : Clinical Chemistry and Laboratory Medicine. 43, 7, p. 735-740

Research output: Contribution to journalArticleAcademicpeer-review

Flavonoid galangin prevents smooth muscle fatigue of pig urinary bladder

Dambros, M., de Jongh, R., van Koeveringe, G. A., Bast, A., Beerens - Heijnen, C. G. M. & van Kerrebroeck, P. E. V. A., 1 Jan 2005, In : Journal of Pharmacy and Pharmacology. 57, 5, p. 617-622

Research output: Contribution to journalArticleAcademicpeer-review

Galangin protects pig detrusor nerves from repetitive field stimulation and anoxia/glucopenia injury

Dambros, M., de Jongh, R., van Koeveringe, G. A., Bast, A. & van Kerrebroeck, P. E. V. A., 1 Jan 2005, In : Urology. 66, 6, p. 1327-1331

Research output: Contribution to journalArticleAcademicpeer-review

Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood

Swennen, E. L. R., Bast, A. & Dagnelie, P. C., 1 Jan 2005, In : European Journal of Immunology. 35, 3, p. 852-858

Research output: Contribution to journalArticleAcademicpeer-review

No role of DT-diaphorase (NQO1) in the protection against oxidized quercetin

Boots, A. W., Bast, A. & Haenen, G. R., 1 Jan 2005, In : Febs Letters. 579, 3, p. 677-682

Research output: Contribution to journalArticleAcademicpeer-review

Pro-apoptotic effects of the flavonoid luteolin in rat H4IIE cells

Michels, G., Watjen, W., Niering, P., Steffan, B., Thi, Q. H., Chovolou, Y., Kampkotter, A., Bast, A., Proksch, P. & Kahl, R., 1 Jan 2005, In : Toxicology. 206, 3, p. 337-348

Research output: Contribution to journalArticleAcademicpeer-review

Rehabilitation Decreases Exercise-induced Oxidative Stress in Chronic Obstructive Pulmonary Disease

Mercken, E. M., Hageman, G. J., Schols, A. M., Akkermans, M. A., Bast, A. & Wouters, E. F., 1 Jan 2005, In : American Journal of Respiratory and Critical Care Medicine. 172, 8, p. 994-1001

Research output: Contribution to journalArticleAcademicpeer-review

Theophylline prevents NAD(+) depletion via PARP-1 inhibition in human pulmonary epithelial cells

Moonen, H. J., Geraets, L., Vaarhorst, A., Bast, A., Wouters, E. F. & Hageman, G. J., 1 Jan 2005, In : Biochemical and Biophysical Research Communications. 338, 4, p. 1805-1810

Research output: Contribution to journalArticleAcademicpeer-review

The reversibility of the glutathionyl-quercetin adduct spreads oxidized quercetin-induced toxicity

Boots, A. W., Balk, J. M., Bast, A. & Haenen, G. R., 1 Jan 2005, In : Biochemical and Biophysical Research Communications. 338, 2, p. 923-929

Research output: Contribution to journalArticleAcademicpeer-review

2004

A new approach to assess the total antioxidant capacity using the TEAC assay

Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M. & Bast, A., 1 Jan 2004, In : Food Chemistry. 88, p. 567-570

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay

Arts, M. J. T. J., Haenen, G. R., Voss, H. P. & Bast, A., 1 Jan 2004, In : Food and Chemical Toxicology. 42, 1, p. 45-49

Research output: Contribution to journalArticleAcademicpeer-review

Dose-response relationships with special refrence to antioxidants

Bast, A. & Haenen, G. R. M. M., 1 Jan 2004, Functional food: Safety aspects. Commission Food Safety & Eisenbrand, G. (eds.). Deutsche Forschungsgemeinschaft, p. 98-111

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia

de Franceschi, L., Turrini, F., Honczarenko, M., Ayi, K., Rivera, A., Fleming, M. D., Law, T., Mannu, F., Kuypers, F. A., Bast, A., van der Vijgh, W. J. F. & Brugnara, C., 1 Jan 2004, In : Haematologica-the Hematology Journal. 89, 11, p. 1287-1298

Research output: Contribution to journalArticleAcademicpeer-review

Lecithinized copper,zinc-superoxide dismutase as a protector against doxorubicin-induced cardiotoxicity in mice

den Hartog, G. J. M., Haenen, G. R. M. M., Boven, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2004, In : Toxicology and Applied Pharmacology. 194, 2, p. 180-188 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipoic acid protects efficiently only against a specific form of peroxynitrite-induced damage

Rezk, B. M., Haenen, G. R., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2004, In : Journal of Biological Chemistry. 279, 11, p. 9693-9697

Research output: Contribution to journalArticleAcademicpeer-review

Possible (enzymatic) routes and biological sites for metabolic reduction of BNP7787, a new protector against cisplatin-induced side-effects

Verschraagen, M., Boven, E., Torun, E., Hausheer, F. H., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2004, In : Biochemical Pharmacology. 68, 3, p. 493-502

Research output: Contribution to journalArticleAcademicpeer-review

Relaxant effects of estradiol through non-genomic pathways in male and female pig bladder smooth muscle

Dambros, M., van Koeveringe, G. A., Bast, A. & van Kerrebroeck, P. E. V. A., 1 Jan 2004, In : Pharmacology. 72, 2, p. 121-127

Research output: Contribution to journalArticleAcademicpeer-review

Sustained protective effects of 7-monohydroxyethylrutoside in an in vivo model of cardiac ischemia-reperfusion

De Celle, T., Heeringa, P., Strzelecka, A. E., Bast, A., Smits, J. F. M. & Janssen, B. J. A., 1 Jan 2004, In : European Journal of Pharmacology. 494, 2-3, p. 205-212

Research output: Contribution to journalArticleAcademicpeer-review