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Research Output

(-)-Epicatechin metabolites promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade inflammation

Milenkovic, D., Declerck, K., Guttman, Y., Kerem, Z., Claude, S., Weseler, A. R., Bast, A., Schroeter, H., Morand, C. & Vanden Berghe, W., Mar 2020, In : Biochemical Pharmacology. 173, 16 p., 113699.

Research output: Contribution to journalArticleAcademicpeer-review

7-monohydroxyethylrutoside protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week

van Acker, F. A. A., van Acker, S. A. B. E., Kramer, K., Haenen, G. R. M. M., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2000, In : Clinical Cancer Research. 6, p. 1337-1347 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Accelerated aging during chronic oxidative stress: a role for PARP-1

Boesten, D. M., de Vos-Houben, J. M., Timmermans, L., den Hartog, G. J., Bast, A. & Hageman, G. J., 1 Jan 2013, In : Oxidative Medicine and Cellular Longevity. 2013, 10 p., 680414.

Research output: Contribution to journalArticleAcademicpeer-review

A comparative study between catalase gene therapy and the cardioprotector monohydroxyethylrutoside (MonoHER) in protecting against doxorubicin-induced cardiotoxicity in vitro

Abou el Hassan, M. A., Rabelink, M. J., van der Vijgh, W. J. F., Bast, A. & Hoeben, R. C., 1 Jan 2003, In : British Journal of Cancer. 89, 11, p. 2140-2146 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A critical appraisal of the use of the antioxidant capacity (TEAC) assay in defining optimal structures

Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M. & Bast, A., 1 Jan 2003, In : Food Chemistry. 80, p. 409-414 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Active ingredients leading in health claims on functional foods

de Boer, A., Urlings, M. J. E. & Bast, A., 1 Jan 2016, In : Journal of Functional Foods. 20, p. 587-593 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Acute cocoa Flavanols intake has minimal effects on exercise-induced oxidative stress and nitric oxide production in healthy cyclists: a randomized controlled trial

Decroix, L., Tonoli, C., Soares, D. D., Descat, A., Drittij-Reijnders, M-J., Weseler, A. R., Bast, A., Stahl, W., Heyman, E. & Meeusen, R., 10 Aug 2017, In : Journal of the International Society of Sports Nutrition. 14, 11 p., 28.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Acute eosinophilic pneumonia associated with glyphosate-surfactant exposure

de Raadt, W. M., Wijnen, P. A., Bast, A., Bekers, O. & Drent, M., 2015, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 32, 2, p. 172-175

Research output: Contribution to journalArticleAcademicpeer-review

Adenosine 5' -triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebocontrolled cross-over trial in healthy humans

Arts, I. C. W., Coolen, E., Bours, M. J. L., Huyghebaert, N., Stuart, M. A. C., Bast, A. & Dagnelie, P. C., 1 Jan 2012, In : Journal of the International Society of Sports Nutrition. 9, 1, p. 16

Research output: Contribution to journalArticleAcademicpeer-review

Adverse food-drug interactions

de Boer, A., van Hunsel, F. & Bast, A., 19 Oct 2015, In : Regulatory Toxicology and Pharmacology. 73, 3, p. 859-865

Research output: Contribution to journalArticleAcademicpeer-review

Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 alpha increase in epidermal in vitro model

Zanoni, T. B., Pedrosa, T. N., Catarino, C. M., Spiekstra, S. W., de Oliveira, D. P., Den Hartog, G., Bast, A., Hagemann, G., Gibbs, S., de Moraes Barros, S. B. & Maria-Engler, S. S., Feb 2018, In : Food and Chemical Toxicology. 112, p. 265-272 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

alpha-Tocopherol inhibits human glutathione S-transferase pi.

van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Biochemical and Biophysical Research Communications. 280, p. 631-633 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Alpha-tocopheryl phosphate is a novel apoptotic agent

Rezk, B. M., van der Vijgh, W. J., Bast, A. & Haenen, G. R., 1 Jan 2007, In : Frontiers in Bioscience. 12, p. 2013-2019

Research output: Contribution to journalArticleAcademicpeer-review

Altered antioxidant status in peripheral skeletal muscle of patients with COPD

Gosker, H. R., Bast, A., Haenen, G. R. M. M., Fischer, M. A. J. G., van der Vusse, G. J., Wouters, E. F. M. & Schols, A. M. W. J., 1 Jan 2005, In : Respiratory Medicine. 99, p. 118-125

Research output: Contribution to journalArticleAcademicpeer-review

Ambient particulate matter induces relaxation of rat aortic rings in vitro.

Knaapen, A. M., den Hartog, G. J. M., Bast, A. & Borm, P. J. A., 1 Jan 2001, In : Human & Experimental Toxicology. 20, 5, p. 259-265 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

An essential difference between the flavonoids monoHER and quercetin in their interplay with the endogenous antioxidant network

Jacobs, H., Moalin, M., Bast, A., van der Vijgh, W. J. & Haenen, G. R. M. M., 1 Jan 2010, In : PLOS ONE. 5, 11, 9 p., e13880.

Research output: Contribution to journalArticleAcademicpeer-review

An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoher and quercetin

Jacobs, H., Moalin, M., van Gisbergen, M. W., Bast, A., van der Vijgh, W. J. F. & Haenen, G. R. M. M., 1 Dec 2011, In : Free Radical Biology and Medicine. 51, 11, p. 2118-2123 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

A new approach to assess the total antioxidant capacity using the TEAC assay

Arts, M. J. T. J., Dallinga, J. W., Voss, H. P., Haenen, G. R. M. M. & Bast, A., 1 Jan 2004, In : Food Chemistry. 88, p. 567-570

Research output: Contribution to journalArticleAcademicpeer-review

Antibiotics exposure and health risks: Chloramphenicol

Hanekamp, J. C. & Bast, A., 1 Jan 2015, In : Environmental Toxicology and Pharmacology. 39, 1, p. 213-220

Research output: Contribution to journalArticleAcademicpeer-review

Anticholinergic Accumulation: A Slumbering Interaction between Drugs and Food Supplements

Vrolijk, M. F., Opperhuizen, A., Jansen, E. H., Bast, A. & Haenen, G. R., Dec 2015, In : Basic & Clinical Pharmacology & Toxicology. 117, 6, p. 427-432 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice

Bruynzeel, A. M., Abou el Hassan, M. A., Schalkwijk, C., Berkhof, J., Bast, A., Niessen, H. W. M. & van der Vijgh, W. J., 1 Jan 2007, In : British Journal of Cancer. 96, 6, p. 937-943

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion

Anson, N. M., Havenaar, R., Bast, A. & Haenen, G. R. M. M., Jan 2010, In : Journal of Cereal Science. 51, 1, p. 110-114

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant and anti-inflammatory potency of different wheat varieties and fractions

Mateo Anson, N., van den Berg, R., Havenaar, R., Haenen, G. R. & Bast, A., 1 Jan 2008, In : Proceedings of the Nutrition Society. 67, OCE1, E56.

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay

Arts, M. J. T. J., Haenen, G. R., Voss, H. P. & Bast, A., 1 Jan 2004, In : Food and Chemical Toxicology. 42, 1, p. 45-49

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidanten overbodig? Prietpraat!

Haenen, G. R. M. M. & Bast, A., 1 Jan 2007, In : Chemisch2Weekblad. 102, 18, p. 26-27

Research output: Contribution to journalArticleProfessional

Antioxidant moet vergoed blijven. N-acetylcysteïne belangrijk voor longfibrosepatiënten.

Drent, M., Dekhuijzen, P. N., Grutters, J. C., Bresser, P., van der Bij, W. & Bast, A., 1 Jan 2010, In : Medisch Contact. 65, 1, p. 30-33

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant status associated with inflammation in sarcoidosis: A potential role for antioxidants

Boots, A. W., Drent, M., Swennen, E. L., Moonen, H. J., Bast, A. & Haenen, G. R., 1 Jan 2009, In : Respiratory Medicine. 103, 3, p. 364-372

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant supplementation and exercise-induced oxidative stress in the 60-year-old as measured by antipyrine hydroxylates

Meijer, E. P., Goris, A. H. C., Senden, J. M. G., Dongen, J. & Bast, A., 1 Jan 2001, In : British Journal of Nutrition. 86, p. 569-575 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A phase I study of monohydroxyethylrutoside in healthy volunteers

Willems, A. M., Bruynzeel, A. M., Kedde, M. A., van Groeningen, C. J., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2006, In : Cancer Chemotherapy and Pharmacology. 57, 5, p. 678-684

Research output: Contribution to journalArticleAcademicpeer-review

A planar conformation and the hydroxyl groups in the b and c rings play a pivotal role in the antioxidant capacity of quercetin and quercetin derivatives

Moalin, M., van Strijdonck, G. P., Beckers, M., Hageman, G., Borm, P., Bast, A. & Haenen, G. R. M. M., Nov 2011, In : Molecules. 16, 11, p. 9636-9650 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Apoptotic, inflammatory, and fibrogenic effects of two different types of multi-walled carbon nanotubes in mouse lung

van Berlo, D., Wilhelmi, V., Boots, A. W., Hullmann, M., Kuhlbusch, T. A., Bast, A., Schins, R. P. & Albrecht, C., Sep 2014, In : Archives of Toxicology. 88, 9, p. 1725-1737 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures.

van den Berg, R., Haenen, G. R. M. M., van den Berg, H. & Bast, A., 1 Jan 1999, In : Food Chemistry. 66, 4, p. 511-518 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A single session of resistance exercise induces oxidative damage in untrained men

Rietjens, S. J., Beelen, M., Koopman, R., van Loon, L. J., Bast, A. & Haenen, G. R., 1 Jan 2007, In : Medicine and Science in Sports and Exercise. 39, 12, p. 2145-2151

Research output: Contribution to journalArticleAcademicpeer-review

Association of man-made mineral fibre exposure and sarcoidlike granulomas.

Drent, M., Bomans, P. H. H., van Suylen, R. J., Lamers, R. J. S., Bast, A. & Wouters, E. F. M., 1 Jan 2000, In : Respiratory Medicine. 94, 8, p. 815-820 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Astaxanthin supplementation does not augment fat use or improve endurance performance.

Res, P. T., Cermak, N. M., Stinkens, R. E., Tollakson, T. J., Haenen, G. R. M. M., Bast, A. & van Loon, L. J. C., Jun 2013, In : Medicine and Science in Sports and Exercise. 45, 6, p. 1158-1165 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

ATP-mediated activation of the NADPH oxidase DUOX1 mediates airway epithelial responses to bacterial stimuli.

Boots, A. W., Hristova-Dijkstra, M. J., Kasahara, D. I., Haenen, G. R., Bast, A. & van der Vliet, A., 1 Jan 2009, In : Journal of Biological Chemistry. 284, 26, p. 17858-17867

Research output: Contribution to journalArticleAcademicpeer-review

ATP sensitizes H460 lung carcinoma cells to cisplatin-induced apoptosis

Swennen, E. L. R., Ummels, V., Buss, I., Jaehde, U., Bast, A. & Dagnelie, P. C., 30 Mar 2010, In : Chemico-Biological Interactions. 184, 3, p. 338-345 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers.

van den Berg, R., van Vliet, T., Broekmans, W. M. R., Cnubben, N. H. P., Vaes, W. H. J., Roza, L., Haenen, G. R. M. M., Bast, A. & van den Berg, H., 1 Jan 2001, In : Journal of Nutrition. 131, p. 1714-1722 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Basic Red 51, a permitted semi-permanent hair dye, is cytotoxic to human skin cells: Studies in monolayer and 3D skin model using human keratinocytes (HaCaT)

Zanoni, T. B., Tiago, M., Faiao-Flores, F., Moraes de Barros, S. B., Bast, A., Hageman, G., de Oliveira, D. P. & Maria-Engler, S. S., 1 Jan 2014, In : Toxicology Letters. 227, 2, p. 139-149

Research output: Contribution to journalArticleAcademicpeer-review

Bioavailability and metabolism

Stahl, W., van den Berg, H., Arthur, J., Bast, A., Dainty, J., Faulks, R. M., Gartner, C., Haenen, G. R. M. M. & et, A., 1 Jan 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 39-100 61 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bioavailability and pharmacokinetics of the cardioprotecting flavonoid 7-monohydroxyethylrutoside in mice

Abou el Hassan, M. A., Kedde, M., Zwiers, U. T., Tourn, E., Haenen, G. R. M. M., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2003, In : Cancer Chemotherapy and Pharmacology. 52, 5, p. 371-376 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Bioavailability of ferulic acid is determined by its bioaccessibility

Mateo Anson, N., van den Berg, R., Havenaar, R., Bast, A. & Haenen, G., 1 Jan 2009, In : Journal of Cereal Science. 49, 2, p. 296-300

Research output: Contribution to journalArticleAcademicpeer-review

Biomarkers

Griffiths, H. R., Moller, L., Bartosz, G., Bast, A., Bertoni-Freddari, C., Collins, A., Cooke, M., Coolen, S., Haenen, G. R. M. M., Hoberg, A. M., Loft, S., Lun, J., Olinski, R., Parry, J., Pompella, A., Poulsen, H. & Verhagen, H., 1 Jan 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 101-108 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biomarkers of adaptive responses in human health

Bast, A., 15 Oct 2019, In : Toxicology Letters. 314, p. S26-S26 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Bioprocessing of wheat bran improves in vitro bioaccessibility and colonic metabolism of phenolic compounds.

Mateo Anson, N., Selinheimo, E., Havenaar, R., Aura, A. M., Mattila, I., Lehtinen, P., Bast, A., Poutanen, K. & Haenen, G. R., 1 Jan 2009, In : Journal of Agricultural and Food Chemistry. 57, 14, p. 6148-6155

Research output: Contribution to journalArticleAcademicpeer-review

Bioprocessing of Wheat Bran in Whole Wheat Bread Increases the Bioavailability of Phenolic Acids in Men and Exerts Antiinflammatory Effects ex Vivo.

Mateo Anson, N., Aura, A. M., Selinheimo, E., Mattila, I., Poutanen, K., van den Berg, R., Havenaar, R., Bast, A. & Haenen, G. R. M. M., 1 Jan 2011, In : Journal of Nutrition. 141, 1, p. 137-143 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Botanical health products, positioning and requirements for effective and safe use

Bast, A., Chandler, R. F., Choy, P. C., Delmulle, L. M., Gruenwald, J., Halkes, S. B. A., Keller, K., Koeman, J. H., Peters, P., Przyrembel, H., de Ree, E. M., Renwick, A. G. & Vermeer, I. T. M., 1 Jan 2002, In : Environmental Toxicology and Pharmacology. 12, p. 195-211 7 p.

Research output: Contribution to journalArticleAcademicpeer-review