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Research Output

1998

Maternal and fetal plasma concentrations of endothelin, lipidhydroperoxides, glutathione peroxidase and fibronectin in relation to abnormal umbilical artery velocimetry.

Karsdorp, V. H. M., Dekker, G. A., Bast, A., van Kamp, G. J., Bouman, A. A., van Vugt, J. M. G. & van Geijn, H. P., 1 Jan 1998, In : European Journal of Obstetrics & Gynecology and Reproductive Biology. 80, 1, p. 39-44 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

The role of prostanoids in ozone-induced changes in airway responsiveness: receptor activation-specific prostanoid release.

Hoof, H. J. M., Zijlstra, F. J., Voss, H. P., Tak, C. J. A. M., van Bree, L. & Bast, A., 1 Jan 1998, In : Environmental Toxicology and Pharmacology. 5, 1, p. 69-78 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tumour necrosis factor-alpha induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.

Pennings, H. J., Kramer, K., Bast, A., Buurman, W. A. & Wouters, E. F. M., 1 Jan 1998, In : European Respiratory Journal. 12, 1, p. 45-49 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

1999

Applicability of an improved Trolox equivalent antioxidant capacity (TEAC) assay for evaluation of antioxidant capacity measurements of mixtures.

van den Berg, R., Haenen, G. R. M. M., van den Berg, H. & Bast, A., 1 Jan 1999, In : Food Chemistry. 66, 4, p. 511-518 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nitric Oxide Radical Scavenging of Flavonoids

Haenen, G. R. M. M. & Bast, A., 1 Jan 1999, In : Methods in Enzymology. 301, p. 490-503 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nitric oxide synthase inhibition by dimaprit and dimaprit analogues.

Paquay, J. B. G., Hoen, P. A., Bast, A., Timmerman, H. & Haenen, G. R. M. M., 1 Jan 1999, In : British Journal of Pharmacology. 127, 2, p. 331-334 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Van voorproever tot toxicoloog

Bast, A., 3 Dec 1999, Maastricht: Universiteit Maastricht.

Research output: Book/ReportInaugural speechPopular

Open Access
File
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2000

7-monohydroxyethylrutoside protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week

van Acker, F. A. A., van Acker, S. A. B. E., Kramer, K., Haenen, G. R. M. M., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2000, In : Clinical Cancer Research. 6, p. 1337-1347 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Association of man-made mineral fibre exposure and sarcoidlike granulomas.

Drent, M., Bomans, P. H. H., van Suylen, R. J., Lamers, R. J. S., Bast, A. & Wouters, E. F. M., 1 Jan 2000, In : Respiratory Medicine. 94, 8, p. 815-820 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of emphysema and training on glutathione oxidation in the hamster diaphragm

Heunks, L. M. A., Bast, A., van Herwaarden, C. L. A., Haenen, G. R. M. M. & Dekhuijzen, P. N. R., 1 Jan 2000, In : Journal of Applied Physiology. 88, p. 2054-2061 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Flavonoids can replace alpha-tocopherol as an antioxidant

van Acker, F. A. A., Schouten, O., Haenen, G. R. M. M., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2000, In : Febs Letters. 473, p. 145-148 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inhibition of nitric oxide synthase by nasal decongestants

Westerveld, G. J., Voss, H. P., van der Hee, R. M., de Haan-Koelewijn, G. J. N., den Hartog, G. J. M., Scheeren, R. A. & Bast, A., 1 Jan 2000, In : European Respiratory Journal. 16, p. 437-444 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vitro screening of antitumour agents for cardiotoxicity by means of isolated mouse left atria

van Acker, F. A. A., van Acker, S. A. B. E., Haenen, G. R. M. M., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2000, In : Anticancer Research. 20, p. 4483-4488 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Protection against nitric oxide toxicity by tea

Paquay, J. B. G., Haenen, G. R. M. M., Stender, G., Wiseman, S. A., Tijburg, L. B. M. & Bast, A., 1 Jan 2000, In : Journal of Agricultural and Food Chemistry. 48, p. 5768-5772 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Quantification of the nonenzymatic fast and slow TRAP in a postaddition assay in human seminal plasma and the antioxidant contributions of various seminal compounds

Rhemrev, J. P. T., van Overveld, F. W. P. C., Haenen, G. R. M. M., Teerlink, T., Bast, A. & Vermeiden, J. P. W., 1 Jan 2000, In : Journal of Andrology. 21, p. 913-920 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Reduction of the NO-mediated response in the rat aorta by metalloporphyrins

Vreman, H. J., Haenen, G. R. M. M., Stevenson, D. K. & Bast, A., 1 Jan 2000, In : Canadian Journal of Physiology and Pharmacology. 78, p. 457-461 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Stability of monoHER in an aqueous formulation for i.v. administration

Abou el Hassan, M. A., Touw, D. J., Wilhelm, A. J., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2000, In : International Journal of Pharmaceutics. 15, 211, p. 51-56 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Synthesis of 1-substituted 7-cyano-2,3-diphenylindolizines and evaluation of antioxidant properties

Ystby, O. B., Dalhus, B., Gundersen, L. L., Rise, F., Bast, A. & Haenen, G. R. M. M., 1 Jan 2000, In : European Journal of Organic Chemistry. p. 3763-3770 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Synthesis of novel 3,7-substituted-2-(3',4'-dihydroxyphenyl)flavones with improved antioxidant activity

van Acker, F. A. A., Hageman, G. J., Haenen, G. R. M. M., van der Vijgh, W. J. F., Bast, A. & Menge, W. M. P. B., 1 Jan 2000, In : Journal of Medicinal Chemistry. 43, p. 3752-3760 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

The predictive value of the antioxidant capacity of structurally related flavonoids using the Trolox equivalent antioxidant capacity TEAC assay

van den Berg, R., Haenen, G. R. M. M., van den Berg, H., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2000, In : Food Chemistry. 70, p. 391-395 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists

Vliet, L. A., Rodenhuis, N., Wikstrom, H., Pugsley, T. A., Serpa, K. A., Meltzer, L. T., Heffner, T. G., Wise, L. D., Laijness, M. E., Huff, R. M., Svensson, K., Haenen, G. R. M. M. & Bast, A., 1 Jan 2000, In : Journal of Medicinal Chemistry. 43, p. 3549-3557 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tyrosine as important contributor to the antioxidant capacity of seminal plasma

van Overveld, F. W. P. C., Haenen, G. R. M. M., Rhemrev, J. P. T., Vermeiden, J. P. W. & Bast, A., 1 Jan 2000, In : Chemico-Biological Interactions. 127, p. 151-161 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2001

alpha-Tocopherol inhibits human glutathione S-transferase pi.

van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Biochemical and Biophysical Research Communications. 280, p. 631-633 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Ambient particulate matter induces relaxation of rat aortic rings in vitro.

Knaapen, A. M., den Hartog, G. J. M., Bast, A. & Borm, P. J. A., 1 Jan 2001, In : Human & Experimental Toxicology. 20, 5, p. 259-265 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Antioxidant supplementation and exercise-induced oxidative stress in the 60-year-old as measured by antipyrine hydroxylates

Meijer, E. P., Goris, A. H. C., Senden, J. M. G., Dongen, J. & Bast, A., 1 Jan 2001, In : British Journal of Nutrition. 86, p. 569-575 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers.

van den Berg, R., van Vliet, T., Broekmans, W. M. R., Cnubben, N. H. P., Vaes, W. H. J., Roza, L., Haenen, G. R. M. M., Bast, A. & van den Berg, H., 1 Jan 2001, In : Journal of Nutrition. 131, p. 1714-1722 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Exercise-induced oxidative stress in older adults as measured by antipyrine oxidation

Meijer, E. P., Coolen, S. A. J., Bast, A. & Westerterp, K. R., 1 Jan 2001, In : Metabolism-Clinical and Experimental. 50, 12, p. 1484-1488 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Exercise training and oxidative stress in the elderly as measured by antipyrine hydroxylation products.

Meijer, E. P., Coolen, S. A. J., Bast, A. & Westerterp, K. R., 1 Jan 2001, In : Free Radical Research. 35, p. 435-443 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., van Acker, F. A. A., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2001, In : Toxicology in Vitro. 15, p. 3-6 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

High-performance liquid chromatography with electrochemical detection for the determination of 7-monohydroxyethylrutoside in plasma.

El Hassan, M., Kedde, M., Bast, A. & van der Vijgh, W. J. F., 1 Jan 2001, In : Journal of Chromatography B. 752, p. 115-121 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hypochlorous acid is a potent inhibitor of GST P1-1.

van Haaften, R. I. M., den Hartog, G. J. M., Evelo, C. T. A., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Chemico-Biological Interactions. 138, p. 77-83 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Inhibition of human glutathione S-transferase P1-1 by tocopherols and alpha-tocopherol derivatives.

van Haaften, R. I. M., Evelo, C. T. A., Penders, J., Eijnwachter, M., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1548, p. 23-28 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interstitial lung disease induced by exogenous agents: factors governing susceptibility.

Nemery, B., Bast, A., Behr, J., Borm, P. J. A., Bourke, S., Camus, P., De Vuyst, P., Jansen, H., Kinnula, V., Lison, D., Pelkonen, O. & Saltini, C., 1 Jan 2001, In : European Respiratory Journal. 18 supp 12, p. 30s-42s 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Lipoic acid: A multifunctional nutraceutical

Bast, A. & Haenen, G. R. M. M., 1 Jan 2001, Nutraceuticals in health and disease prevention. Kramer, K., Hoppe, PP. & Packer, L. (eds.). New York / Basel: Marcel Dekker Inc., 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Masking of antioxidant capacity by the interaction of flavonoids with protein.

Arts, M. J. T. J., Haenen, G. R. M. M., Voss, H. P. & Bast, A., 1 Jan 2001, In : Food and Chemical Toxicology. 39, p. 787-791 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity.

van Acker, F. A. A., Hulshof, J., Haenen, G. R. M. M., Menge, W. M. P. B., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2001, In : Free Radical Biology and Medicine. 31, p. 31-37 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

NF-kappaB activation in sarcoidosis.

Drent, M., van den Berg, R., Haenen, G. R. M. M., van den Berg, H., Wouters, E. F. M. & Bast, A., 1 Jan 2001, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 18, p. 50-56 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

No reduction of alpha-tocopherol quinone by glutathione in rat liver microsomes

van Haaften, R. I. M., Evelo, C. T. A., Haenen, G. R. M. M. & Bast, A., 1 Jan 2001, In : Biochemical Pharmacology. 61, p. 715-719 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Nuclear factor-kappaB activation is higher in peripheral blood mononuclear cells of male smokers.

van den Berg, R., Haenen, G. R. M. M., van den Berg, H. & Bast, A., 1 Jan 2001, In : Environmental Toxicology and Pharmacology. 9, p. 147-151 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Peroxynitrite scavenging of flavonoids: structure activity relationship

Beerens - Heijnen, C. G. M., Haenen, G. R. M. M., Vekemans, J. & Bast, A., 1 Jan 2001, In : Environmental Toxicology and Pharmacology. 10, p. 199-206 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Progressively motile human spermatozoa are well protected against in vitro lipid peroxidation imposed by induced oxidative stress.

Rhemrev, J. P. T., Vermeiden, J. P. W., Haenen, G. R. M. M., de Bruijne, J., Rekers-Mombarg, L. & Bast, A., 1 Jan 2001, In : Andrologia. 33, p. 151-158 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Psychological job demands as a risk factor for common cold in a Dutch working population.

Mohren, D. C. L., Swaen, G. M. H., Borm, P. J. A., Bast, A. & Galama, J. M. D., 1 Jan 2001, In : Journal of Psychosomatic Research. 50, p. 21-27 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Synthesis of 5-substituted pyrrolo[1,2-b]pyridazines with antioxidant properties

Ostby, O. B., Gundersen, L. L., Rise, F., Antonson, O., Fosnes, K., Larsen, V., Bast, A., Custers, I. & Haenen, G. R. M. M., 1 Jan 2001, In : Archiv der Pharmazie. 334, p. 21-24 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Transcription factor NF-kappaB as a potential biomarker for oxidative stress.

van den Berg, R., Haenen, G. R. M. M., van den Berg, H. & Bast, A., 1 Jan 2001, In : British Journal of Nutrition. 86 suppl 1, p. S121-S127 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2002

Bioavailability and metabolism

Stahl, W., van den Berg, H., Arthur, J., Bast, A., Dainty, J., Faulks, R. M., Gartner, C., Haenen, G. R. M. M. & et, A., 1 Jan 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 39-100 61 p.

Research output: Contribution to journalArticleAcademicpeer-review

Biomarkers

Griffiths, H. R., Moller, L., Bartosz, G., Bast, A., Bertoni-Freddari, C., Collins, A., Cooke, M., Coolen, S., Haenen, G. R. M. M., Hoberg, A. M., Loft, S., Lun, J., Olinski, R., Parry, J., Pompella, A., Poulsen, H. & Verhagen, H., 1 Jan 2002, In : Molecular Aspects of Medicine. 23, 1-3, p. 101-108 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Botanical health products, positioning and requirements for effective and safe use

Bast, A., Chandler, R. F., Choy, P. C., Delmulle, L. M., Gruenwald, J., Halkes, S. B. A., Keller, K., Koeman, J. H., Peters, P., Przyrembel, H., de Ree, E. M., Renwick, A. G. & Vermeer, I. T. M., 1 Jan 2002, In : Environmental Toxicology and Pharmacology. 12, p. 195-211 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Decreased redox state in red blood cells from patients with sarcoidosis

Rothkrantz-Kos, S., Drent, M., Vuil, H., de Boer, M., Bast, A., Wouters, E. F. M., Roos, D. & van Dieijen-Visser, M. P., 1 Jan 2002, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 19, 2, p. 114-120 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers

van Schooten, F. J., Besarati Nia, A., de Flora, S., D'Agostini, F., Izzotti, A., Camoirano, A., Balm, A. J. M., Dallinga, J. W., Bast, A., Haenen, G. R. M. M. & et, A., 1 Jan 2002, In : Cancer Epidemiology Biomarkers & Prevention. 11, 2, p. 167-175 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Efficacy of HOCI scavenging by sulfurcontaining compounds: antioxidant activity of glutathione disulfide?

den Hartog, G. J., Haenen, G. R. M. M., Vegt, E., van der Vijgh, W. J. F. & Bast, A., 1 Jan 2002, In : Biological Chemistry. 383, p. 709-713

Research output: Contribution to journalArticleAcademicpeer-review