Adaptive responses in relation to health effect and safety of nutrition

Research output

Research output per year 2018 2018 2019 2020 2021 2022 2023 2024

• 53 Article
• 20 (Systematic) Review article
• 9 Conference Abstract/Poster in journal
• 8 Doctoral Thesis
• 6 More
  • 3 Editorial
  • 2 Comment/Letter to the editor
  • 1 Paper

Research output per year

Research output per year

Search results

• 2024

  Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells

  Janssen, A. W. F., Jansen Holleboom, W., Rijkers, D., Louisse, J., Hoekstra, S. A., Schild, S., Vrolijk, M. F., Hoogenboom, R. L. A. P. & Beekmann, K., 14 Mar 2024, In: Frontiers in Toxicology. 6, p. 1347965

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Drug-Gene Risk Stratification in Patients with Suspected Drug-Induced Interstitial Lung Disease

  Drent, M., Wijnen, P. A., Jessurun, N. T., Harmsze, A. M., Bekers, O. & Bast, A., Apr 2024, In: Drug Safety. 47, 4, p. 355-363 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The effect of cations and epigallocatechin gallate on in vitro salivary lubrication

  Agorastos, G., Van uitert, E., Van halsema, E., Scholten, E., Bast, A. & Klosse, P., 1 Jan 2024, In: Food Chemistry. 430, 9 p., 136968.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2023

  EU's next generation risk assessment: hurdles and opportunities for new approach methodologies

  Otto, S., Vrolijk, M. F. & de Boer, A., Mar 2023, In: Journal für Verbraucherschutz und Lebensmittelsicherheit-Journal of Consumer Protection and Food Safety. 18, p. 3-17 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Heart Rate Variability and Somatization in Adolescents With Irritable Bowel Syndrome

  Semen, M., Lychkovska, O., Kaminskyy, D., Yavorskyi, O., Semen, K. & Yelisyeyeva, O., 1 Apr 2023, In: Journal of Neurogastroenterology and Motility. 29, 2, p. 208-217 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Heart rate variability correlates with the effect of sulforaphane on calorie-induced inflammation in healthy participants: a randomized placebo-controlled study

  Van steenwijk, H. P., van Osch, F. H. M., Troost, F. J., Bast, A., de Boer, A. & Semen, K. O., 1 Jun 2023, In: Clinical Nutrition Open Science. 49, p. 140-156

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Higher levels of circulating desphospho-uncarboxylated matrix Gla protein over time are associated with worse survival: the prospective Maastricht Intensive Care COVID cohort

  Mulder, M. M. G., Schellens, J., Sels, J-W. E. M., van Rosmalen, F., Hulshof, A-M., de Vries, F., Segers, R., Mihl, C., van Mook, W. N. K. A., Bast, A., Spronk, H. M. H., Henskens, Y. M. C., van der Horst, I. C. C., ten Cate, H., Schurgers, L. J., Drent, M. & van Bussel, B. C. T., 18 Dec 2023, In: Journal of Intensive Care. 11, 1, 12 p., 63.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Instrumental classification of beer based on mouthfeel

  Agorastos, G., Klosse, B., Hoekstra, A., Meuffels, M., Welzen, J. J. M. J., Halsema, V., Bast, A. & Klosse, P., 1 Jun 2023, In: International Journal of Gastronomy and Food Science. 32, 10 p., 100697.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Mixture effects of tetrodotoxin (TTX) and drugs targeting voltage-gated sodium channels on spontaneous neuronal activity in vitro

  Tukker, A. M., Vrolijk, M. F., van Kleef, R. G. D. M., Sijm, D. T. H. M. & Westerink, R. H. S., 15 Jan 2023, In: Toxicology Letters. 373, p. 53-61 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Nutrient composition of fresh produce-Assessing variability between European countries to substantiate nutrition and health claims

  Beltramo, B., Bast, A., Dilien, H. & de Boer, A., 1 May 2023, In: Journal of Food Composition and Analysis. 118, 10 p., 105201.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• On the importance of saliva in mouthfeel sensations

  Agorastos, G., van Halsema, E., Bast, A. & Klosse, P., 1 Mar 2023, In: International Journal of Gastronomy and Food Science. 31, 8 p., 100667.

  Research output: Contribution to journal › Article › Academic › peer-review

• Sulforaphane as a potential modifier of calorie-induced inflammation: a double-blind, placebo-controlled, crossover trial

  van Steenwijk, H. P., Vinken, A., van Osch, F. H. M., Peppelenbos, H., Troost, F. J., Bast, A., Semen, K. O. & de Boer, A., 28 Nov 2023, In: Frontiers in nutrition. 10, 12 p., 1245355.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The beneficial effect of sulforaphane on platelet responsiveness during caloric load: a single-intake, double-blind, placebo-controlled, crossover trial in healthy participants

  van Steenwijk, H. P., Winter, E., Knaven, E., Brouwers, J. F., van Baardwijk, M., van Dalum, J. B., Luijendijk, T. J. C., van Osch, F. H. M., Troost, F. J., Bast, A., Semen, K. O. & de Boer, A., 6 Jul 2023, In: Frontiers in nutrition. 10, 14 p., 1204561.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Understanding the phenomenon of food waste valorisation from the perspective of supply chain actors engaged in it

  Rao, M., Bast, A. & de Boer, A., 22 Sept 2023, In: Agricultural and Food Economics. 11, 1, 20 p., 40.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2022

  Assessing the influence of information on the intention to use dietary supplements: An online questionnaire study

  Lenssen, K. G. M., Garcia Fuentes, A., Van Osch, F. H. M., Bast, A. & De Boer, A., 1 May 2022, In: Journal of Functional Foods. 92, 10 p., 105017.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Investigating the cytotoxicity of per- and polyfluoroalkyl substances in HepG2 cells: a Structure-Activity Relationship approach

  Amstutz, V. H., Cengo, A., Gehres, F., Sijm, D. T. H. M. & Vrolijk, M. F., Oct 2022, In: Toxicology. 480, 9 p., 153312.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Lubrication behavior of ex-vivo salivary pellicle influenced by tannins, gallic acid and mannoproteins

  Agorastos, G., van Nielen, O., van Halsema, E., Scholten, E., Bast, A. & Klosse, P., Dec 2022, In: Heliyon. 8, 12, 9 p., e12347.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The complexity of proving health effects with data on ‘traditional use’: A critical perspective on supporting botanical health claims

  Lenssen, K. G. M., Bast, A. & De Boer, A., 1 Feb 2022, In: Trends in Food Science & Technology. 120, p. 338-343 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms

  Amstutz, V. H., Cengo, A., Sijm, D. T. H. M. & Vrolijk, M. F., 28 Feb 2022, In: Toxicology. 468, 9 p., 153116.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2021

  Effect of oral or intragastric delivery of the bitter tastant quinine on food intake and appetite sensations: a randomised crossover trial

  Klaassen, T., Keszthelyi, D., Alleleyn, A. M. E., Wilms, E., Bast, A., Masclee, A. A. M. & Troost, F. J., 14 Jan 2021, In: British Journal of Nutrition. 125, 1, p. 92-100 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Gastrointestinal digestion of dietary advanced glycation endproducts increases their pro-inflammatory potential

  van der Lugt, T., Vrolijk, M. F., Bovee, T. F. H., van Leeuwen, S. P. J., Vonsovic, S., Hamers, A., Opperhuizen, A. & Bast, A., 7 Aug 2021, In: Food & Function. 12, 15, p. 6691-6696 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• How does scientific information reach the consumer? A case study among students into providing verbal information on dietary supplements at point of purchase

  Lenssen, K., Bast, A. & de Boer, A., 3 Apr 2021, In: International Journal of Food Sciences and Nutrition. 72, 3, p. 402-417 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Hypoxia-induced mitochondrial abnormalities in cells of the placenta

  Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Kaminski, I., Geomini, I., Lemmens, T., Schiffers, P. M. H., van Schooten, F. J. & Remels, A. H. V., 12 Jan 2021, In: PLOS ONE. 16, 1, 26 p., 0245155.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Let Them Eat Fish!-Exploring the Possibility of Utilising Unwanted Catch in Food Bank Parcels in The Netherlands

  Rao, M., Bilić, L., Duwel, J., Herentrey, C., Lehtinen, E., Lee, M., Díaz Calixto, M. A., Bast, A. & de Boer, A., 11 Nov 2021, In: Foods. 10, 11, 17 p., 2775.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Red yeast rice (Monascus purpureus) supplements: Case series assessment of spontaneously reported cases to The Netherlands Pharmacovigilance Centre Lareb

  Vrolijk, M. F., van de Koppel, S. & van Hunsel, F., Apr 2021, In: British Journal of Clinical Pharmacology. 87, 4, p. 2146-2151 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Role of Drug-Gene Interactions and Pharmacogenetics in Simvastatin-Associated Pulmonary Toxicity

  Jessurun, N. T., Drent, M., Wijnen, P. A., Harmsze, A. M., van Puijenbroek, E. P., Bekers, O. & Bast, A., Nov 2021, In: Drug Safety. 44, 11, p. 1179-1191 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Sensory-specific satiety, the variety effect and physical context: Does change of context during a meal enhance food intake?

  Hendriks, A. E. M., Nederkoorn, C., van Lier, I. M. J., Belkom, B. V., Bast, A. & Havermans, R. C., 1 Aug 2021, In: Appetite. 163, 6 p., 105179.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Valorized Food Processing By-Products in the EU: Finding the Balance between Safety, Nutrition, and Sustainability

  Rao, M., Bast, A. & De Boer, A., 15 Apr 2021, In: Sustainability. 13, 8, 18 p., 4428.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2020

  Analysis and reflection on the role of the 90-day oral toxicity study in European chemical risk assessment

  Vrolijk, M., Deluyker, H., Bast, A. & de Boer, A., Nov 2020, In: Regulatory Toxicology and Pharmacology. 117, 10 p., 104786.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Dietary Advanced Glycation Endproducts Decrease Glucocorticoid Sensitivity In Vitro

  van der Lugt, T., Weseler, A. R., Vrolijk, M. F., Opperhuizen, A. & Bast, A., 1 Feb 2020, In: Nutrients. 12, 2, 12 p., 441.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Effects of Monomeric and Oligomeric Flavanols on Kidney Function, Inflammation and Oxidative Stress in Runners: A Randomized Double-Blind Pilot Study

  Semen, K. O., Weseler, A. R., Janssen, M. J. W., Drittij-Reijnders, M. J., le Noble, J. L. M. L. & Bast, A., 1 Jun 2020, In: Nutrients. 12, 6, 15 p., 1634.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Gastrointestinal digestion of dietary advanced glycation endproducts using an in vitro model of the gastrointestinal tract (TIM-1)

  van der Lugt, T., Venema, K., van Leeuwen, S., Vrolijk, M. F., Opperhuizen, A. & Bast, A., 1 Jul 2020, In: Food & Function. 11, 7, p. 6297-6307 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Haemodynamic effects of the flavonoid quercetin in rats revisited

  Vrolijk, M. F., van Essen, H., Opperhuizen, A., Bast, A. & Janssen, B. J., Apr 2020, In: British Journal of Pharmacology. 177, 8, p. 1841-1852 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Inter-individual differences in pharmacokinetics of vitamin B6: A possible explanation of different sensitivity to its neuropathic effects

  Vrolijk, M. F., Hageman, G. J., van de Koppel, S., van Hunsel, F. & Bast, A., Jun 2020, In: PharmaNutrition. 12, 7 p., 100188.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Non-steroidal anti-inflammatory drugs increase urinary neutrophil gelatinase-associated lipocalin in recreational runners

  Semen, K. O., van der Doelen, R. H. A., van der Lugt, M., van Dam, D. G. H. A., Reimer, J., Stassen, F. R. M., Janssen, L., Janssen, P. K. C., Janssen, M. J. W., Bast, A. & le Noble, J. L. M. L., Oct 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 10, p. 1888-1895 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity

  Vangrieken, P., Remels, A. H., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J. & Schiffers, P. M. H., Dec 2020, In: Hypertension Research. 43, 12, p. 1361-1374 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Ranking Self-reported Gastrointestinal Side Effects of Pharmacotherapy in Sarcoidosis

  Drent, M., Proesmans, V. L. J., Elfferich, M. D. P., Jessurun, N. T., de Jong, S. M. G., Ebner, N. M., Lewis, E. D. O. & Bast, A., 1 Apr 2020, In: Lung. 198, 2, p. 395-403 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Should botanical health claims be substantiated with evidence on traditional use? Reviewing the stakeholders’ arguments

  Lenssen, K., Bast, A. & de Boer, A., Dec 2020, In: PharmaNutrition. 14, 9 p., 100232.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers

  Jessurun, N. T., Wijnen, P. A., Bast, A., van Puijenbroek, E. P., Bekers, O. & Drent, M., Apr 2020, In: International journal of molecular sciences. 21, 8, 9 p., 2770.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2019

  Exploring the mechanism of within-meal variety and sensory-specific satiation

  Hendriks, A. E. M., Havermans, R. C., Nederkoorn, C. & Bast, A., Dec 2019, In: Food Quality and Preference. 78, 6 p., 103740.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• International Perspectives on Substantiating theEfficacy of Herbal Dietary Supplements andHerbal Medicines Through Evidence onTraditional Use

  Lenssen, K., Bast, A. & de Boer, A., Jul 2019, In: Comprehensive Reviews in Food Science and Food Safety. 18, 4, p. 910-922 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury

  Zoubek, M. E., Woitok, M. M., Sydor, S., Nelson, L. J., Bechmann, L. P., Lucena, M. I., Andrade, R. J., Bast, A., Koek, G. H., Trautwein, C. & Cubero, F. J., Jan 2019, In: Journal of Pathology. 247, 1, p. 110-122 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Self-reported Gastrointestinal Side Effects of Antifibrotic Drugs in Dutch Idiopathic Pulmonary Fibrosis patients

  Proesmans, V. L. J., Drent, M., Elfferich, M. D. P., Wijnen, P. A. H. M., Jessurun, N. T. & Bast, A., Oct 2019, In: Lung. 197, 5, p. 551-558 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Towards improved pharmacotherapy in pulmonary arterial hypertension. Can diet play a role?

  Semen, K. O. & Bast, A., Apr 2019, In: Clinical Nutrition ESPEN. 30, p. 159-169 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• VKORC1 and CYP2C9 Polymorphisms: A Case Report in a Dutch Family with Pulmonary Fibrosis

  Wijnen, P., Drent, M., Bekers, O., Verschakelen, J. & Bast, A., 1 Mar 2019, In: International journal of molecular sciences. 20, 5, 10 p., 1160.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access
• 2018

  Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 alpha increase in epidermal in vitro model

  Zanoni, T. B., Pedrosa, T. N., Catarino, C. M., Spiekstra, S. W., de Oliveira, D. P., Den Hartog, G., Bast, A., Hagemann, G., Gibbs, S., de Moraes Barros, S. B. & Maria-Engler, S. S., Feb 2018, In: Food and Chemical Toxicology. 112, p. 265-272 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Clarifying the health claim assessment procedure of EFSA will benefit functional food innovation

  Lenssen, K., Bast, A. & de Boer, A., Aug 2018, In: Journal of Functional Foods. 47, p. 386-396 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Dietary Advanced Glycation Endproducts Induce an Inflammatory Response in Human Macrophages in Vitro

  van der Lugt, T., Weseler, A. R., Gebbink, W. A., Vrolijk, M. F., Opperhuizen, A. & Bast, A., 1 Dec 2018, In: Nutrients. 10, 12, 10 p., 1868.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Dietary supplement intake during pregnancy; better safe than sorry?

  de Boer, A., Bast, A. & Godschalk, R., Jun 2018, In: Regulatory Toxicology and Pharmacology. 95, p. 442-447 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

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• Lipase diffusion in oil-filled, alginate micro- and macrobeads

  van Leusden, P., den Hartog, G. J. M., Bast, A., Postema, M., van der Linden, E. & Sagis, L. M. C., 1 Dec 2018, In: Food Hydrocolloids. 85, p. 242-247 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review