• P Debyelaan25, DEB25

    6229 HX Maastricht

    Netherlands

Research Output

2020

Oxygen Sensors in Atherosclerosis

Demandt, J. A. F., 2020, Ridderprint. 302 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
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48 Downloads (Pure)

Selection for Medical School: the quest for validity

Schreurs, S., 2020, Maastricht: Ipskamp Printing BV. 152 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
58 Downloads (Pure)

SOX17 expression and its down-regulation by promoter methylation in cervical adenocarcinoma in situ and adenocarcinoma

Hopman, A. N. H., Moshi, J. M., Hoogduin, K. J., Ummelen, M., Henfling, M. E. R., van Engeland, M., Wouters, K. A. D., Stoop, H., Looijenga, L. H. J. & Ramaekers, F. C. S., Feb 2020, In : Histopathology. 76, 3, p. 383-393 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019

A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients

Sternkopf, M., Thoroee-Boveleth, S., Beck, T., Oleschko, K., Erlenkoetter, A., Tschulena, U., Steppan, S., Speer, T., Goettsch, C., Jankowski, V., Jankowski, J. & Noels, H., Jul 2019, In : Toxins. 11, 7, 17 p., 389.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

ADAM8 in the cardiovascular system: An innocent bystander with clinical use?

van der Vorst, E. P. C. & Donners, M. M. P. C., Jul 2019, In : Atherosclerosis. 286, p. 147-149 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Adipose tissue macrophages do not affect atherosclerosis development in mice

Bijnen, M., van de Gaar, J., Vroomen, M., Gijbels, M. J., de Winther, M., Schalkwijk, C. G. & Wouters, K., Feb 2019, In : Atherosclerosis. 281, p. 31-37 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

ALK immunohistochemistry positive, FISH negative NSCLC is infrequent, but associated with impaired survival following treatment with crizotinib

Thunnissen, E., Lissenberg-Witte, B., van den Heuvel, M. M., Monkhorst, K., Skov, B. G., Sorensen, J. B., Mellemgaard, A., Dingemans, A. M. C., Speel, E. J. M., de Langen, A. J., Hashemi, S. M. S., Bahce, I., van der Drift, M. A., Looijen-Salamon, M. G., Gosney, J., Postmus, P. E., Samii, S. M. S., Duplaquet, F., Weynand, B., Durando, X. & 15 others, Penault-Llorca, F., Finn, S., Grady, A. O., Oz, B., Akyurek, N., Buettner, R., Wolf, J., Bubendorf, L., Duin, S., Marondel, L., Heukamp, L. C., Timens, W., Schuuring, E. M. D., Pauwels, P. & Smit, E. F., Dec 2019, In : Lung Cancer. 138, p. 13-18 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

AMP-Activated Protein Kinase Signalling

Neumann, D. & Viollet, B., 1 Feb 2019, In : International journal of molecular sciences. 20, 3, 5 p., 766.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances

Vollmer, T., Ljungberg, B., Jankowski, V., Jankowski, J., Glorieux, G. & Stegmayr, B. G., 10 Oct 2019, In : Scientific Reports. 9, 11 p., 14525.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis

Brandsma, E., Kloosterhuis, N. J., Koster, M., Dekker, D. C., Gijbels, M. J. J., van der Velden, S., Rios-Morales, M., van Faassen, M. J. R., Loreti, M. G., de Bruin, A., Fu, J., Kuipers, F., Bakker, B. M., Westerterp, M., de Winther, M. P. J., Hofker, M. H., van de Sluis, B. & Koonen, D. P. Y., 4 Jan 2019, In : Circulation Research. 124, 1, p. 94-100 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A quarter century of decline of autopsies in the Netherlands

Latten, B. G. H., Overbeek, L. I. H., Kubat, B., Hausen, A. Z. & Schouten, L. J., Dec 2019, In : European Journal of Epidemiology. 34, 12, p. 1171-1174 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis

Mentrup, T., Theodorou, K., Cabrera-Cabrera, F., Hethig, A. O., Happ, K., Gijbels, M., Gradtke, A-C., Rabe, B., Fukumori, A., Steiner, H., Tholey, A., Fluhrer, R., Donners, M. & Schroeder, B., Apr 2019, In : Journal of Experimental Medicine. 216, 4, p. 807-830 24 p.

Research output: Contribution to journalArticleAcademicpeer-review

Atypical Chemokine Receptors in Cardiovascular Disease

Gencer, S., van der Vorst, E. P. C., Aslani, M., Weber, C., Doering, Y. & Duchene, J., Apr 2019, In : Thrombosis and Haemostasis. 119, 4, p. 534-541 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Building a Professional Identity and an Academic Career Track in Translational Medicine

van Dijk, S. J., Domenighetti, A. A., Gomez-Ospina, N., Hunter, P., Lindemans, C. A., Melotte, V., van Rossum, A. M. C. & Rosenblum, N. D., 3 Jul 2019, In : Frontiers in medicine. 6, 6 p., 151.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Characterization of the thymus in Lrp4 myasthenia gravis: Four cases

Koneczny, I., Rennspiess, D., Marcuse, F., Dankerlui, N., Hamid, M. A., Mane-Damas, M., Maessen, J., Van Schil, P., Saxena, A., Zisimopoulou, P., Lazaridis, K., Woodhall, M., Karagiorgou, K., Tzartos, J., Tzartos, S., De Baets, M. H., Molenaar, P. C., Marx, A., zur Hausen, A., Losen, M. & 1 others, Martinez-Martinez, P., Jan 2019, In : Autoimmunity Reviews. 18, 1, p. 50-55 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Comprehensive biomarker analyses identifies HER2, EGFR, MET RNA expression and thymidylate synthase 5 ' UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer

Yoshikawa, T., Aoyama, T., Sakamaki, K., Oshima, T., Lin, J., Zhang, S., Sapari, N. S., Soong, R., Tan, I., Chan, X. B., Bottomley, D., Hewitt, L. C., Arai, T., Teh, B. T., Epstein, D., Ogata, T., Kameda, Y., Miyagi, Y., Tsuburaya, A., Morita, S. & 2 others, Grabsch, H. & Tan, P., 2019, In : Journal of Cancer. 10, 21, p. 5130-5138 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma

Jan 2019, In : Gastric Cancer. 22, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Correction to: Consensus on the pathological definition and classification of poorly cohesive gastric carcinoma

Mar 2019, In : Gastric Cancer. 22, 2, p. 421-421 1 p.

Research output: Contribution to journalErratum / corrigendumAcademic

Correction to: Exploring burnout and the association with the educational climate in pediatric residents in Thailand (vol 19, 245, 2019)

Puranitee, P., Stevens, F. F. C. J., Pakakasama, S., Plitponkarnpim, A., Vallibhakara, S. A-O., Busari, J. O., Heeneman, S. & van Mook, W. N. K. A., 1 Aug 2019, In : BMC Medical Education. 19, 1 p., 296.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

Correction to: KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Hewitt, L. C., Saito, Y., Wang, T., Matsuda, Y., Oosting, J., Silva, A. N. S., Slaney, H. L., Melotte, V., Hutchins, G., Tan, P., Yoshikawa, T., Arai, T. & Grabsch, H. I., Nov 2019, In : Gastric Cancer. 22, 6, p. 1204-1205 2 p.

Research output: Contribution to journalErratum / corrigendumAcademic

CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease

Doering, Y., van der Vorst, E. P. C., Duchene, J., Jansen, Y., Gencer, S., Bidzhekov, K., Atzler, D., Santovito, D., Rader, D. J., Saleheen, D. & Weber, C., 5 Mar 2019, In : Circulation. 139, 10, p. 1338-1340 3 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer

Kather, J. N., Pearson, A. T., Halama, N., Jaeger, D., Krause, J., Loosen, S. H., Marx, A., Boor, P., Tacke, F., Neumann, U. P., Grabsch, H. I., Yoshikawa, T., Brenner, H., Chang-Claude, J., Hoffmeister, M., Trautwein, C. & Luedde, T., Jul 2019, In : Nature Medicine. 25, 7, p. 1054-+ 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction

Reiche, M. E., den Toom, M., Willemsen, L., van Os, B., Gijbels, M. J. J., Gerdes, N., Aarts, S. A. B. M. & Lutgens, E., Oct 2019, In : BMJ Open Diabetes Research and Care. 7, 1, 10 p., 000829.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death

Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slutter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. K., Nicolaes, G. A. F., Daemen, M. J. A. P. & 4 others, Weber, C., Gerdes, N., de Winther, M. P. J. & Lutgens, E., 21 Jan 2019, In : European Heart Journal. 40, 4, p. 372-382 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH

Aarts, S., Reiche, M., den Toom, M., Gijbels, M., Beckers, L., Gerdes, N. & Lutgens, E., 11 Oct 2019, In : Scientific Reports. 9, 11 p., 14702.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Development and initial validation of a dual-purpose questionnaire capturing mentors' and mentees' perceptions and expectations of the mentoring process

Heeneman, S. & de Grave, W., 8 May 2019, In : BMC Medical Education. 19, 13 p., 133.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

DLL3 expression in large cell neuroendocrine carcinoma (LCNEC) and association with molecular subtypes and neuroendocrine profile

Hermans, B. C. M., Derks, J. L., Thunnissen, E., van Suylen, R. J., den Bakker, M. A., Groen, H. J. M., Smit, E. F., Damhuis, R. A., van den Broek, E. C., Ruland, A., Speel, E. J. M. & Dingemans, A. M. C., Dec 2019, In : Lung Cancer. 138, p. 102-108 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial

Sundar, R., Ng, A., Zouridis, H., Padmanabhan, N., Sheng, T., Zhang, S., Lee, M. H., Ooi, W. F., Qamra, A., Inam, I., Hewitt, L. C., So, J. B-Y., Koh, V., Nankivell, M. G., Langley, R. E., Allum, W. H., Cunningham, D., Rozen, S. G., Yong, W. P., Grabsch, H. I. & 1 others, Tan, P., Dec 2019, In : European Journal of Cancer. 123, p. 48-57 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Exploring burnout and depression of Thai medical students: the psychometric properties of the Maslach burnout inventory

Puranitee, P., Saetang, S., Sumrithe, S., Busari, J. O., van Mook, W. N. K. A. & Heeneman, S., 29 Nov 2019, In : International Journal of Medical Education. 10, p. 223-229 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exploring burnout and the association with the educational climate in pediatric residents in Thailand

Puranitee, P., Stevens, F. F. C. J., Pakakasama, S., Plitponkarnpim, A., Arj-OngVallibhakara, S., Busari, J. O., Heeneman, S. & van Mook, W. N. K. A., 5 Jul 2019, In : BMC Medical Education. 19, 10 p., 245.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exploring Validity Evidence Associated With Questionnaire-Based Tools for Assessing the Professional Performance of Physicians: A Systematic Review

van der Meulen, M. W., Smirnova, A., Heeneman, S., Egbrink, M. G. A. O., van der Vleuten, C. P. M. & Lombarts, K. M. J. M. H., Sep 2019, In : Academic Medicine. 94, 9, p. 1384-1397 14 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Extracellular traps derived from macrophages, mast cells, eosinophils and neutrophils are generated in a time-dependent manner during atherothrombosis

Pertiwi, K. R., de Boer, O. J., Mackaaij, C., Pabittei, D. R., de Winter, R. J., Li, X. & van der Wal, A. C., Apr 2019, In : Journal of Pathology. 247, 4, p. 505-512 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Fluorescent labelling of membrane fatty acid transporter CD36 (SR-B2) in the extracellular loop

Liu, Y., Rodriguez-Calvo, R., Wang, S., Zhu, X., Broers, J. L. V., Glatz, J. F. C., Luiken, J. J. F. P. & Neumann, D., 23 Jan 2019, In : PLOS ONE. 14, 1, 14 p., 0210704.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gene Promoter Methylation in Endometrial Carcinogenesis

Cornel, K. M. C., Wouters, K., Van de Vijver, K. K., van der Wurff, A. A. M., van Engeland, M., Kruitwagen, R. F. P. M. & Pijnenborg, J. M. A., Apr 2019, In : Pathology & oncology Research. 25, 2, p. 659-667 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis

van der Vorst, E. P. C., Peters, L. J. F., Mueller, M., Gencer, S., Yan, Y., Weber, C. & Doering, Y., 22 May 2019, In : Frontiers in Pharmacology. 10, 24 p., 531.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report

van der Vorst, E. P. C., Mandl, M., Mueller, M., Neideck, C., Jansen, Y., Hristov, M., Gencer, S., Peters, L. J. F., Meiler, S., Feld, M., Geiselhoeringer, A-L., de Jong, R. J., Ohnmacht, C., Noels, H., Soehnlein, O., Drechsler, M., Weber, C. & Doering, Y., Apr 2019, In : Arteriosclerosis Thrombosis and Vascular Biology. 39, 4, p. 685-693 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing

van Kuijk, K., Kuppe, C., Betsholtz, C., Vanlandewijck, M., Kramann, R. & Sluimer, J. C., 1 Oct 2019, In : Cardiovascular Research. 115, 12, p. 1705-1715 11 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta-analysis of transcriptional subtypes

de Santiago, I., Yau, C., Heij, L., Middleton, M. R., Markowetz, F., Grabsch, H., Dustin, M. L. & Sivakumar, S., 15 Aug 2019, In : International Journal of Cancer. 145, 4, p. 1125-1137 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Increasing value in research: cost evaluations in health professions education

Schreurs, S., Cleutjens, K. & Egbrink, M. G. A. O., Dec 2019, In : Medical Education. 53, 12, p. 1171-1173 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Alcala, N., Leblay, N., Gabriel, A. A. G., Mangiante, L., Hervas, D., Giffon, T., Sertier, A. S., Ferrari, A., Derks, J., Ghantous, A., Delhomme, T. M., Chabrier, A., Cuenin, C., Abedi-Ardekani, B., Boland, A., Olaso, R., Meyer, H., Altmuller, J., Le Calvez-Kelm, F., Durand, G. & 50 others, Voegele, C., Boyault, S., Moonen, L., Lemaitre, N., Lorimier, P., Toffart, A. C., Soltermann, A., Clement, J. H., Saenger, J., Field, J. K., Brevet, M., Blanc-Fournier, C., Galateau-Salle, F., Le Stang, N., Russell, P. A., Wright, G., Sozzi, G., Pastorino, U., Lacomme, S., Vignaud, J. M., Hofman, M., Hofman, P., Brustugun, O. T., Lund-Iversen, M., de Montpreville, V. T., Muscarella, L. A., Graziano, P., Popper, H., Stojsic, J., Deleuze, J. F., Herceg, Z., Viari, A., Nuernberg, P., Pelosi, G., Dingemans, A. M. C., Milione, M., Roz, L., Brcic, L., Volante, M., Papotti, M. G., Caux, C., Sandoval, J., Hernandez-Vargas, H., Brambilla, E., Speel, E. J. M., Girard, N., Lantuejoul, S., McKay, J. D., Foll, M. & Fernandez-Cuesta, L., 20 Aug 2019, In : Nature Communications. 10, p. 1-21 21 p., 3407.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Integrative Multi-Omics Analysis Of Human Atherosclerosis Reveals An Intraplaque Bleeding Associated Network, Which Offers Better Prediction Of Disease Stage

Jin, H., Goossens, P., Karel, J., Daemen, M., Sluimer, J. & Biessen, E., 3 Aug 2019, In : Atherosclerosis. 287, p. e63-e63 1 p., EAS19-0625.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Is the sum of positive neuroendocrine immunohistochemical stains useful for diagnosis of large cell neuroendocrine carcinoma (LCNEC) on biopsy specimens?

Derks, J. L., Dingemans, A-M. C., van Suylen, R-J., den Bakker, M. A., Damhuis, R. A. M., van den Broek, E. C., Speel, E-J. & Thunnissen, E., Mar 2019, In : Histopathology. 74, 4, p. 555-566 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Joint ESM-EVBO meetings: past, present, and future

Sluimer, J. C. & Houben, A. J. H. M., 15 Mar 2019, In : Cardiovascular Research. 115, 4, p. E46-E48 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Hewitt, L. C., Saito, Y., Wang, T., Matsuda, Y., Oosting, J., Silva, A. N. S., Slaney, H. L., Melotte, V., Hutchins, G., Tan, P., Yoshikawa, T., Arai, T. & Grabsch, H. I., Nov 2019, In : Gastric Cancer. 22, 6, p. 1193-1203 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Large cell neuroendocrine carcinoma with a solitary brain metastasis and low Ki-67: a unique subtype

Hermans, B. C. M., Derks, J. L., Groen, H. J. M., Stigt, J. A., van Suylen, R. J., Hillen, L. M., van den Broek, E. C., Speel, E. J. M. & Dingemans, A-M. C., Dec 2019, In : Endocrine Connections . 8, 12, p. 1600-1606 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Liver disease predominates in a mouse model for mild human Zellweger spectrum disorder

Berendse, K., Boek, M., Gijbels, M., Van der Wel, N. N., Klouwer, F. C., van den Bergh-Weerman, M. A., Shinde, A. B., Ofman, R., Poll-The, B. T., Houten, S. M., Baes, M., Wanders, R. J. A. & Waterham, H. R., 1 Oct 2019, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1865, 10, p. 2774-2787 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access