• P Debyelaan25, DEB25

    6229 HX Maastricht

    Netherlands

Research Output

2020

A digital mRNA expression signature to classify challenging Spitzoid melanocytic neoplasms

Hillen, L. M., Geybels, M. S., Spassova, I., Becker, J. C., Gambichler, T., Garmyn, M., zur Hausen, A., van den Oord, J. & Winnepenninckx, V., Jul 2020, In : FEBS Open Bio. 10, 7, p. 1326-1341 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

Dohmen, M., Krieg, S., Agalaridis, G., Zhu, X., Shehata, S. N., Pfeiffenberger, E., Amelang, J., Buetepage, M., Buerova, E., Pfaff, C. M., Chanda, D., Geley, S., Preisinger, C., Sakamoto, K., Luescher, B., Neumann, D. & Vervoorts, J., 25 Feb 2020, In : Nature Communications. 11, 1, 18 p., 1032.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A national study to assess outcomes of definitive chemoradiation regimens in proximal esophageal cancer

de Vos-Geelen, J., Hoebers, F. J. P., Geurts, S. M. E., Hoeben, A., de Greef, B. T. A., Voncken, F. E. M., Bogers, J. H. A., Braam, P. M., Muijs, C. K. T., de Jong, M. A., Kasperts, N., Rozema, T., Jeene, P. M., Blom, G. J., van Dieren, J. M., Hulshof, M. C. C. M., van Laarhoven, H. W. M., Grabsch, H., Lemmens, V. E. P. P., Tjan-Heijnen, V. C. G. & 1 others, Nieuwenhuijzen, G. A. P., 2 Aug 2020, In : Acta Oncologica. 59, 8, p. 895-903 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation

Zewinger, S., Reiser, J., Jankowski, V., Alansary, D., Hahm, E., Triem, S., Klug, M., Schunk, S. J., Schmit, D., Kramann, R., Koerbel, C., Ampofo, E., Laschke, M. W., Selejan, S-R., Paschen, A., Herter, T., Schuster, S., Silbernagel, G., Sester, M., Sester, U. & 15 others, Assmann, G., Bals, R., Kostner, G., Jahnen-Dechent, W., Menger, M. D., Rohrer, L., Maerz, W., Boehm, M., Jankowski, J., Kopf, M., Latz, E., Niemeyer, B. A., Fliser, D., Laufs, U. & Speer, T., Jan 2020, In : Nature Immunology. 21, 1, p. 30-41 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

AQP5 enriches for stem cells and cancer origins in the distal stomach

Tan, S. H., Swathi, Y., Tan, S., Goh, J., Seishima, R., Murakami, K., Oshima, M., Tsuji, T., Phuah, P., Liang Thing Tan, Wong, E., Fatehullah, A., Sheng, T., Ho, S. W. T., Grabsch, H., Srivastava, S., Teh, M., Denil, S. L. I. J., Mustafah, S., Tan, P. & 4 others, Shabbir, A., So, J., Yeoh, K. G. & Barker, N., Feb 2020, In : Nature. 578, 7795, p. 437-443 27 p.

Research output: Contribution to journalArticleAcademicpeer-review

Between trust and control: Teachers' assessment conceptualisations within programmatic assessment

Schut, S., Heeneman, S., Bierer, B., Driessen, E., van Tartwijk, J. & van Der Vleuten, C., Jun 2020, In : Medical Education. 54, 6, p. 528-537 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Biobanking in Molecular Biomarker Research for the Early Detection of Cancer

Lommen, K., Odeh, S., de Theije, C. C. & Smits, K. M., Apr 2020, In : Cancers. 12, 4, 11 p., 776.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Biological and translational implications of enteric nerves in colorectal cancer: When tumors get nervous

Rademakers, G., 2020, Maastricht: Maastricht University.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
103 Downloads (Pure)

Chorioamnionitis induces enteric nervous system injury: effects of timing and inflammation in the ovine fetus

Heymans, C., de Lange, I. H., Lenaerts, K., Kessels, L. C. G. A., Hadfoune, M., Rademakers, G., Melotte, V., Boesmans, W., Kramer, B. W., Jobe, A. H., Saito, M., Kemp, M. W., van Gemert, W. G. & Wolfs, T. G. A. M., 3 Sep 2020, In : Molecular Medicine. 26, 1, 10 p., 82.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chronic Intra-Uterine Ureaplasma parvum Infection Induces Injury of the Enteric Nervous System in Ovine Fetuses

Heymans, C., de Lange, I. H., Hutten, M. C., Lenaerts, K., de Ruijter, N. J. E., Kessels, L. C. G. A., Rademakers, G., Melotte, V., Boesmans, W., Saito, M., Usuda, H., Stock, S. J., Spiller, O. B., Payne, M. S., Kramer, B. W., Newnham, J. P., Jobe, A. H., Kemp, M. W., van Gemert, W. G. & Wolfs, T. G. A. M., 17 Mar 2020, In : Frontiers in Immunology. 11, 13 p., 189.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chronic Intra-Uterine Ureaplasma parvum Infection Induces Injury of the Enteric Nervous System in Ovine Fetuses (vol 11, 189, 2020)

Heymans, C., de Lange, I. H., Huetten, M. C., Lenaerts, K., de Ruijter, N. J. E., Kessels, L. C. G. A., Rademakers, G., Melotte, V., Boesmans, W., Saito, M., Usuda, H., Stock, S. J., Spiller, O. B., Beeton, M. L., Payne, M. S., Kramer, B. W., Newnham, J. P., Jobe, A. H., Kemp, M. W., van Gemert, W. G. & 1 others, Wolfs, T. G. A. M., 15 Apr 2020, In : Frontiers in Immunology. 11, 2 p., 672.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

COVID-19 and programmatic assessment

Bala, L., van der Vleuten, C., Freeman, A., Torre, D., Heeneman, S. & Sam, A. H., Aug 2020, In : The Clinical Teacher. 17, 4, p. 420-422 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Development, establishment and validation of in vitro and ex vivo assays of vascular calcification

Holmar, J., Noels, H., Boehm, M., Bhargava, S., Jankowski, J. & Orth-Alampour, S., 17 Sep 2020, In : Biochemical and Biophysical Research Communications. 530, 2, p. 462-470 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Development of the intrinsic innervation of the small bowel mucosa and villi

Hao, M. M., Fung, C., Boesmans, W., Lowette, K., Tack, J. & Vanden Berghe, P., Jan 2020, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 318, 1, p. G53-G65 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Differential Role for Activating Fc gamma RIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice

Asare, Y., Koehncke, J., Selle, J., Simsekyilmaz, S., Jankowski, J., Shagdarsuren, G., Gessner, J. E., Bernhagen, J. & Shagdarsuren, E., 17 Jun 2020, In : Frontiers in physiology. 11, 11 p., 673.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Editorial on the Special Issue "Comorbidities in Chronic Kidney Disease"

Noels, H. & Jankowski, J., Jun 2020, In : Toxins. 12, 6, 5 p., 384.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer

Xing, M., Ooi, W. F., Tan, J., Qamra, A., Lee, P-H., Li, Z., Xu, C., Padmanabhan, N., Lim, J. Q., Guo, Y. A., Yao, X., Amit, M., Ng, L. M., Sheng, T., Wang, J., Huang, K. K., Anene-Nzelu, C. G., Ho, S. W. T., Ray, M., Ma, L. & 26 others, Fazzi, G., Lim, K. J., Wijaya, G. C., Zhang, S., Nandi, T., Yan, T., Chang, M. M., Das, K., Isa, Z. F. A., Wu, J., Poon, P. S. Y., Lam, Y. N., Lin, J. S., Tay, S. T., Lee, M. H., Tan, A. L. K., Ong, X., White, K., Rozen, S. G., Beer, M., Foo, R. S. Y., Grabsch, H. I., Skanderup, A. J., Li, S., Teh, B. T. & Tan, P., 1 Jun 2020, In : Journal of Clinical Investigation. 130, 6, p. 3005-3020 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

High Prevalence of Human Polyomavirus 7 in Cholangiocarcinomas and Adjacent Peritumoral Hepatocytes: Preliminary Findings

Klufah, F., Mobaraki, G., Chteinberg, E., Alharbi, R. A., Winnepenninckx, V., Speel, E. J. M., Rennspiess, D., Damink, S. W. O., Neumann, U. P., Kurz, A. K., Samarska, I. & zur Hausen, A., Aug 2020, In : Microorganisms. 8, 8, 18 p., 1125.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

How is self-regulated learning documented in e-portfolios of trainees? A content analysis

van der Gulden, R., Heeneman, S., Kramer, A. W. M., Laan, R. F. J. M., Scherpbier-de Haan, N. D. & Thoonen, B. P. A., 26 Jun 2020, In : BMC Medical Education. 20, 1, 13 p., 205.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Impact of sex and age on chemotherapy efficacy, toxicity and survival in localised oesophagogastric cancer: A pooled analysis of 3265 individual patient data from four large randomised trials (OE02, OE05, MAGIC and ST03)

Athauda, A., Nankivell, M., Langley, R. E., Alderson, D., Allum, W., Grabsch, H. I., Starling, N., Chau, I. & Cunningham, D., Sep 2020, In : European Journal of Cancer. 137, p. 45-56 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Interobserver, intraobserver, and interlaboratory variability in reporting pT4a colon cancer

Klaver, C. E. L., Bulkmans, N., Drillenburg, P., Grabsch, H. I., van Grieken, N. C. T., Karrenbeld, A., Koens, L., van Lijnschoten, I., Meijer, J., Nagtegaal, I. D., Sagaert, X., Seldenrijk, K., van Velthuysen, M. F., Bruggink, A. H., Tanis, P. J. & Snaebjornsson, P., Feb 2020, In : Virchows Archiv. 476, 2, p. 219-230 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development

van der Vorst, E. P. C., Daissormont, I., Aslani, M., Seijkens, T., Wijnands, E., Lutgens, E., Duchene, J., Santovito, D., Doering, Y., Halvorsen, B., Aukrust, P., Weber, C., Hoepken, U. E. & Biessen, E. A. L., Feb 2020, In : Thrombosis and Haemostasis. 120, 2, p. 344-347 4 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

Large negative lymph nodes - a surrogate for immune activation in rectal cancer patients?

Ruisch, J. E., Kloft, M., Fazzi, G. E., Melenhorst, J., Magee, D. R. & Grabsch, H., Sep 2020, In : Pathology Research and Practice. 216, 9, 6 p., 153106.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Massive gas embolisms in diving fatalities visualized by radiology and neuropathology

de Bakker, H. M., Kubat, B., Soerdjbalie-Maikoe, V., Vester, M., de Bakker, O. J. G. B., van Hulst, R. A. & de Bakker, B. S., 2020, In : Clinical Neuropathology. 39, 5, p. 221-226 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Meaningful mapping of remediation in longitudinal and developmental assessment models

Heeneman, S. & Schut, S., Oct 2020, In : Medical Education. 54, 10, p. 866-868 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access

Mentorship Needs for Radiation Oncology Residents: Implications for Programme Design

Croke, J., Milne, E., Bezjak, A., Millar, B. A., Giuliani, M. & Heeneman, S., Apr 2020, In : Clinical oncology. 32, 4, p. E119-E125 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Microscopic intramural extension of rectal cancer after neoadjuvant chemoradiation: A meta-analysis based on individual patient data

Verrijssen, A-S., Guillem, J., Perez, R., Bujko, K., Guedj, N., Habr-Gama, A., Houben, R., Goudkade, D., Melenhorst, J., Buijsen, J., Vanneste, B., Grabsch, H. I., Bellezzo, M., Fonseca, G. P., Verhaegen, F., Berbee, M. & Van Limbergen, E. J., Mar 2020, In : Radiotherapy and Oncology. 144, p. 37-45 9 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Molecular biomarkers in skull base chordoma

Yakkioui, Y., 2020, Maastricht: ProefschriftMaken. 164 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
103 Downloads (Pure)

Multicentre study on the consistency of PD-L1 immunohistochemistry as predictive test for immunotherapy in non-small cell lung cancer

Butter, R., 't Hart, N. A., Hooijer, G. K. J., Monkhorst, K., Speel, E-J., Theunissen, P., Thunnissen, E., Von der Thüsen, J. H., Timens, W. & van de Vijver, M. J., Jul 2020, In : Journal of Clinical Pathology. 73, 7, p. 423-430 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Multidisciplinary management of stage II-III gastric and gastro-oesophageal junction cancer

Wagner, A. D., Lordick, F., Grabsch, H., Terashima, M., Terada, M., Yoshikawa, T., Boku, N., Kataoka, K., Smyth, E. C., Mauer, M., Haustermans, K. & Moehler, M. H., Jan 2020, In : European Journal of Cancer. 124, p. 67-76 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions

Sternkopf, M., Nagy, M., Baaten, C. C. F. M. J., Kuijpers, M. J. E., Tullemans, B. M. E., Wirth, J., Theelen, W., Mastenbroek, T. G., Lehrke, M., Winnerling, B., Baerts, L., Marx, N., De Meester, I., Doring, Y., Cosemans, J. M. E. M., Daiber, A., Steven, S., Jankowski, J., Heemskerk, J. W. M. & Noels, H., Mar 2020, In : Arteriosclerosis Thrombosis and Vascular Biology. 40, 3, p. E65-E77 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neuronal programming by microbiota regulates intestinal physiology

Obata, Y., Castano, A., Boeing, S., Bon-Frauches, A. C., Fung, C., Fallesen, T., De Aguero, M. G., Yilmaz, B., Lopes, R., Huseynova, A., Horswell, S., Maradana, M. R., Boesmans, W., Vanden Berghe, P., Murray, A. J., Stockinger, B., Macpherson, A. J. & Pachnis, V., Feb 2020, In : Nature. 578, 7794, p. 284-289 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction

Curaj, A., Schumacher, D., Rusu, M., Staudt, M., Li, X., Simsekyilmaz, S., Jankowski, V., Jankowski, J., Dumitrascu, A. R., Hausenloy, D. J., Schuh, A. & Liehn, E. A., May 2020, In : International journal of molecular sciences. 21, 10, 12 p., 3685.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Organoid Models of Neuroendocrine Cell Growth and Tumorigenesis

Dayton, T., Den Hartigh, L. A., Levy, S., van den Berg, J. B., Kok, N., Buikhuisen, W., Hartemink, K., Speel, E. J., Valk, G. D., Tesselaar, M., Vriens, M. R. & Clevers, H., Mar 2020, In : Neuroendocrinology. 110, p. 24-24 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Outcomes-Based Selection Into Medical School: Predicting Excellence in Multiple Competencies During the Clinical Years

Schreurs, S., Cleutjens, K. B. J. M., Cleland, J. & Egbrink, M. G. A. O., Sep 2020, In : Academic Medicine. 95, 9, p. 1411-1420 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Oxygen Sensors in Atherosclerosis

Demandt, J. A. F., 2020, Ridderprint. 302 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
222 Downloads (Pure)

Past, Present and Future of Epigenetics in Adrenocortical Carcinoma

Ettaieb, M., Kerkhofs, T., van Engeland, M. & Haak, H., May 2020, In : Cancers. 12, 5, 21 p., 1218.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

PD-L1 Expression and a High Tumor Infiltrate of CD8+Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma

Wuerdemann, N., Gultekin, S. E., Puetz, K., Wittekindt, C., Huebbers, C. U., Sharma, S. J., Eckel, H., Schubotz, A. B., Gattenloehner, S., Buettner, R., Speel, E-J., Klussmann, J. P., Wagner, S. & Quaas, A., Aug 2020, In : International journal of molecular sciences. 21, 15, 16 p., 5228.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension

Kerkhofs, D., van Hagen, B. T., Milanova, I. V., Schell, K. J., van Essen, H., Wijnands, E., Goossens, P., Blankesteijn, W. M., Unger, T., Prickaerts, J., Biessen, E. A., van Oostenbrugge, R. J. & Foulquier, S., 25 Jul 2020, In : Theranostics. 10, 21, p. 9512-9527 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prediction Power on Cardiovascular Disease of Neuroimmune Guidance Cues Expression by Peripheral Blood Monocytes Determined by Machine-Learning Methods

Zhang, H., Bredewold, E. O. W., Vreeken, D., Duijs, J. M. G. J., de Boer, H. C., Kraaijeveld, A. O., Jukema, J. W., Pijls, N. H., Waltenberger, J., Biessen, E. A. L., van der Veer, E. P., van Zonneveld, A. J. & van Gils, J. M., Sep 2020, In : International journal of molecular sciences. 21, 17, 18 p., 6364.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review

de Ruijter, T. C., van der Heide, F., Smits, K. M., Aarts, M. J., van Engeland, M. & Heijnen, V. C. G., 31 Jan 2020, In : Breast Cancer Research. 22, 1, 12 p., 13.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort

Thunnissen, E., Kerr, K. M., Dafni, U., Bubendorf, L., Finn, S. P., Soltermann, A., Biernat, W., Cheney, R., Verbeken, E., Warth, A., Marchetti, A., Speel, E-J. M., Pokharel, S., Quinn, A. M., Monkhorst, K., Navarro, A., Madsen, L. B., Tsourti, Z., Geiger, T., Kammler, R. & 5 others, Peters, S., Stahel, R. A., European Thoracic Oncology Platform Lungscape Consortium, Dingemans, A-M. & Ruland, A. M., May 2020, In : Modern Pathology. 33, 5, p. 792-801 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice

Parma, L., Peters, H. A. B., Baganha, F., Sluimer, J. C., de Vries, M. R. & Quax, P. H. A., Feb 2020, In : Cells. 9, 2, 18 p., 336.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Rhabdomyosarcoma of the Adult Prostate: Two Cases With Molecular and Cytogenetic Analyses

Samarska, I., van den Hout, M. C. M., Li, X., van Roermund, J. G. H., Marcelissen, T. A. T., Vanden Bempt, I., Sciot, R. & zur Hausen, A., 2020, In : Pathology Case Reviews. 25, 3, p. 133-137 5 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Role for phosphatidylinositol 4-kinase IIIβ in cardiac metabolic diseases

Sun, A., 2020, Maastricht: Gildeprint Drukkerijen. 132 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
130 Downloads (Pure)

Selection for Medical School: the quest for validity

Schreurs, S., 2020, Maastricht: Ipskamp Printing BV. 152 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
231 Downloads (Pure)