Nuclear Medicine

  • P. Debyelaan 25

    6229 HX Maastricht

    Netherlands

Research Output

2019

Rapid Access to Contrast-Enhanced spectral mammogRaphy in women recalled from breast cancer screening: the RACER trial study design

Neeter, L. M. F. H., Houben, I. P. L., Nelemans, P. J., Van Nijnatten, T. J. A., Pijnappel, R. M., Frotscher, C., Osinga-de Jong, M., Sanders, F., Van Dalen, T., Raat, H. P. J., Essers, B. A. B., Wildberger, J. E., Smidt, M. L. & Lobbes, M. B., 23 Dec 2019, In : Trials. 20, 1, 10 p., 759.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Ultrasound to Evaluate Neonatal Spinal Dysraphism: A First-Line Alternative to CT and MRI

Orman, G., Tijssen, M. P. M., Seyfert, D., Gassner, I. & Huisman, T. A. G. M., Sep 2019, In : Journal of Neuroimaging. 29, 5, p. 553-564 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

2016

Thyroid Hormone Activates Brown Adipose Tissue and Increases Non-Shivering Thermogenesis - A Cohort Study in a Group of Thyroid Carcinoma Patients

Broeders, E., Vijgen, G., Havekes, B., Bouvy, N. D., Mottaghy, F. M., Kars, M., Schaper, N. C., Schrauwen, P., Brans, B. & van Marken Lichtenbelt, W., 19 Jan 2016, In : PLOS ONE. 11, 1, 15 p., e0145049.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2015

(18)F-NaF PET/CT: EANM procedure guidelines for bone imaging

Beheshti, M., Mottaghy, F. M., Payche, F., Behrendt, F. F., Van den Wyngaert, T., Fogelman, I., Strobel, K., Celli, M., Fanti, S., Giammarile, F., Krause, B. & Langsteger, W., Oct 2015, In : European Journal of Nuclear Medicine and Molecular Imaging. 42, 11, p. 1767-1777 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

(99m) Tc radiolabeling and biological evaluation of nanoparticles functionalized with a versatile coating ligand

Felber, M., Bauwens, M., Mateos, J. M., Imstepf, S., Mottaghy, F. M. & Alberto, R., 13 Apr 2015, In : Chemistry: a European journal. 21, 16, p. 6090-6099 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

A Practical One-Pot Synthesis of Positron Emission Tomography (PET) Tracers via Nickel-Mediated Radiofluorination

Zlatopolskiy, B. D., Zischler, J., Urusova, E. A., Endepols, H., Kordys, E., Frauendorf, H., Mottaghy, F. M. & Neumaier, B., 1 Jan 2015, In : Chemistry Open. 4, 4, p. 457-462

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Clinical value of (6)(8)Ga-DOTATATE-PET/CT compared to stand-alone contrast enhanced CT for the detection of extra-hepatic metastases in patients with neuroendocrine tumours (NET)

Albanus, D. R., Apitzsch, J., Erdem, Z., Erdem, O., Verburg, F. A., Behrendt, F. F., Mottaghy, F. M. & Heinzel, A., Oct 2015, In : European Journal of Radiology. 84, 10, p. 1866-1872 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Comparison of automatic versus manual procedures for the quantification of dopamine D2 receptor availability using I-123-IBZM-SPECT

Heinzel, A., Shali, S. M., Dafotakis, M., Verburg, F. A., Mottaghy, F. M. & Winz, O. H., Nov 2015, In : Nuclear Medicine Communications. 36, 11, p. 1120-1126

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Detection of coronary artery disease in postmenopausal women: the significance of integrated stress imaging tests in a 4-year prognostic study

Becker, M., Hundemer, A., Zwicker, C., Altiok, E., Krohn, T., Mottaghy, F. M., Lente, C., Kelm, M., Marx, N. & Hoffmann, R., Mar 2015, In : Clinical research in cardiology. 104, 3, p. 258-271

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Detektion einer pleuro-peritonealen Leckage bei Peritonealdialyse mit Hilfe der Peritonealszintigraphie mit SPECT/CT

Fiethen, S., Schlieper, G., Mottaghy, F. M. & Heinzel, A., 1 Jan 2015, In : Nuklearmedizin. 54, 1, p. N5-N6 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

Diagnosis of Brachiocephalic Thrombophlebitis as the Cause of Fever of Unknown Origin by 18F-FDG-PET/CT

Demirev, A., Brans, B., Vanmolkot, F., de Graaf, R., Mottaghy, F. & Bucerius, J., Feb 2015, In : Molecular imaging and radionuclide therapy. 24, 1, p. 25-28 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic Performance of Dedicated Axillary T2- and Diffusion-weighted MR Imaging for Nodal Staging in Breast Cancer

Schipper, R. J., Paiman, M. L., Beets-Tan, R. G. H., Nelemans, P. J., de Vries, B., Heuts, E. M., van de Vijver, K. K., Keymeulen, K. B., Brans, B., Smidt, M. L. & Lobbes, M. B. I., May 2015, In : Radiology. 275, 2, p. 345-355 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Evaluation of a short dynamic (18)F-fluoride PET/CT scanning method to assess bone metabolic activity in spinal orthopedics

Peters, M. J. M., Wierts, R., Jutten, E. M. C., Halders, S. G. E. A., Willems, P. C. P. H. & Brans, B., 1 Jan 2015, In : Annals of Nuclear Medicine. 29, 9, p. 799-809

Research output: Contribution to journalArticleAcademicpeer-review

Final analysis of a prospective trial on functional imaging for nodal staging in patients with prostate cancer at high risk for lymph node involvement

Van den Bergh, L., Lerut, E., Haustermans, K., Deroose, C. M., Oyen, R., Isebaert, S., Budiharto, T., Ameye, F., Mottaghy, F. M., Bogaerts, K., van Poppel, H. & Joniau, S., 1 Jan 2015, In : Urologic oncology-seminars and Original Investigations. 33, 3, p. 109 e 23-109 e 31

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance.

Hanssen, M. J., Wierts, R., Hoeks, J., Gemmink, A., Brans, B., Mottaghy, F. M., Schrauwen, P. & van Marken Lichtenbelt, W. D., Mar 2015, In : Diabetologia. 58, 3, p. 586-595 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Impact of bariatric surgery on carotid artery inflammation and the metabolic activity in different adipose tissues

Bucerius, J., Vijgen, G. H., Brans, B., Bouvy, N. D., Bauwens, M., Rudd, J. H., Havekes, B., Fayad, Z. A., van Marken Lichtenbelt, W. D. & Mottaghy, F. M., May 2015, In : Medicine. 94, 20, 9 p., e725.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Low brown adipose tissue activity in endurance-trained compared with lean sedentary men

Vosselman, M. J., Hoeks, J., Brans, B., Pallubinsky, H., Nascimento, E. B. M., van der Lans, A. A. J., Broeders, E. P., Mottaghy, F. M., Schrauwen, P. & van Marken Lichtenbelt, W. D., Dec 2015, In : International Journal of Obesity. 39, 12, p. 1696-1702 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Molecular imaging of angiogenesis after myocardial infarction by (111)In-DTPA-cNGR and (99m)Tc-sestamibi dual-isotope myocardial SPECT

Hendrikx, G., De Saint-Hubert, M., Dijkgraaf, I., Bauwens, M., Douma, K., Wierts, R., Pooters, I., van den Akker, N. M., Hackeng, T. M., Post, M. J. & Mottaghy, F. M., 28 Jan 2015, In : EJNMMI Research. 5, p. 13-22 10 p., 2.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
3 Citations (Scopus)

No evidence for attenuated stress-induced extrastriatal dopamine signaling in psychotic disorder

Hernaus, D., Collip, D., Kasanova, Z., Winz, O., Heinzel, A., van Amelsvoort, T., Shali, S. M., Booij, J., Rong, Y., Piel, M., Pruessner, J., Mottaghy, F. M. & Myin-Germeys, I., 14 Apr 2015, In : Translational Psychiatry. 5, e547.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Nuclear Targeting with an Auger Electron Emitter Potentiates the Action of a Widely Used Antineoplastic Drug

Imstepf, S., Pierroz, V., Raposinho, P., Bauwens, M., Felber, M., Fox, T., Shapiro, A. B., Freudenberg, R., Fernandes, C., Gama, S., Gasser, G., Mottaghy, F., Santos, I. R. & Alberto, R., Dec 2015, In : Bioconjugate Chemistry. 26, 12, p. 2397-2407 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

PET Imaging of the Human Nicotinic Cholinergic Pathway in Atherosclerosis

Bauwens, M., Mottaghy, F. & Bucerius, J., 1 Jan 2015, In : Current Cardiology Reports. 17, 8, 67.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet

Kusters, D. H., Chatrou, M. L., Willems, B. A., De Saint-Hubert, M., Bauwens, M., van der Vorst, E., Bena, S., Biessen, E. A., Perretti, M., Schurgers, L. J. & Reutelingsperger, C. P., 19 Jun 2015, In : PLOS ONE. 10, 6, 15 p., e0130484.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Pretherapeutic dosimetry before 131I therapy of benign thyroid disease. A clinical practice assessment of dosimetric parameters

Krohn, T., Behrendt, F. F., Heinzel, A., Muller, B., Mottaghy, F. M. & Verburg, F. A., 1 Jan 2015, In : Nuklearmedizin. 54, 3, p. 131-136

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Pseudarthrosis after lumbar spinal fusion: the role of (18)F-fluoride PET/CT

Peters, M., Willems, P., Weijers, R., Wierts, R., Jutten, L., Urbach, C., Arts, C., van Rhijn, L. & Brans, B., Nov 2015, In : European Journal of Nuclear Medicine and Molecular Imaging. 42, 12, p. 1891-1898 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Radiation Exposure of Abdominal Cone Beam Computed Tomography

Sailer, A. M., Schurink, G. W. H., Wildberger, J. E., de Graaf, R., van Zwam, W. H., de Haan, M. W., Kemerink, G. J. & Jeukens, C. R. L. P. N., Feb 2015, In : Cardiovascular and Interventional Radiology. 38, 1, p. 112-120

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Retrospective quality control review of FDG scans in the imaging sub-study of PALETTE EORTC 62072/VEG110727: a randomized, double-blind, placebo-controlled phase III trial

Hristova, I., Boellaard, R., Vogel, W., Mottaghy, F., Marreaud, S., Collette, S., Schoffski, P., Sanfilippo, R., Dewji, R., van der Graaf, W. & Oyen, W. J. G., May 2015, In : European Journal of Nuclear Medicine and Molecular Imaging. 42, 6, p. 848-857

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus

Hanssen, M. J., Hoeks, J., Brans, B., van der Lans, A. A., Schaart, G., van den Driessche, J. J., Jorgensen, J. A., Boekschoten, M. V., Hesselink, M. K., Havekes, B., Kersten, S., Mottaghy, F. M., van Marken Lichtenbelt, W. D. & Schrauwen, P., Aug 2015, In : Nature Medicine. 21, 8, p. 863-865 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

40 Citations (Scopus)

Simulation-based partial volume correction for dopaminergic PET imaging: Impact of segmentation accuracy

Rong, Y., Vernaleken, I., Winz, O. H., Goedicke, A., Mottaghy, F. M. & Kops, E. R., 2015, In : Zeitschrift für Medizinische Physik. 25, 3, p. 230-242

Research output: Contribution to journalArticleAcademicpeer-review

The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity

Broeders, E. P., Nascimento, E. B. M., Havekes, B., Brans, B., Roumans, K. H. M., Tailleux, A., Schaart, G., Kouach, M., Charton, J., Deprez, B., Bouvy, N. D., Mottaghy, F., Staels, B., van Marken Lichtenbelt, W. & Schrauwen, P., 1 Sep 2015, In : Cell Metabolism. 22, 3, p. 418-426 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Scopus)
2014

(18)F-FDG microPET imaging differentiates between septic and aseptic wound healing after orthopedic implant placement: a longitudinal study of an implant osteomyelitis in the rabbit tibia

Odekerken, J. C. E., Brans, B. T., Welting, T. J. M. & Walenkamp, G. H. I. M., Jun 2014, In : Acta Orthopaedica. 85, 3, p. 305-313 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

A dual-labeled Annexin A5 is not suited for SPECT imaging of brain cell death in experimental murine stroke

Zille, M., Harhausenl, D., De Saint-Hubert, M., Michel, R., Reutelingsperger, C. P., Dirnagl, U. & Wunder, A., Sep 2014, In : Journal of Cerebral Blood Flow and Metabolism. 34, 9, p. 1568-1570

Research output: Contribution to journalArticleAcademicpeer-review

A low molecular weight zinc-dipicolylamine-based probe detects apoptosis during tumour treatment better than an annexin V-based probe

Palmowski, K., Rix, A., Lederle, W., Behrendt, F. F., Mottaghy, F. M., Gray, B. D., Pak, K. Y., Palmowski, M. & Kiessling, F., 1 Jan 2014, In : European Radiology. 24, 2, p. 363-370

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
5 Citations (Scopus)

Arterial and fat tissue inflammation are highly correlated : a prospective F-18-FDG PET/CT study

Bucerius, J., Mani, V., Wong, S., Moncrieff, C., Izquierdo-Garcia, D., Machac, J., Fuster, V., Farkouh, M. E., Rudd, J. H. F. & Fayad, Z. A., May 2014, In : European Journal of Nuclear Medicine and Molecular Imaging. 41, 5, p. 934-945

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Breaking the Invulnerability of Cancer Stem Cells: Two-Step Strategy to Kill the Stem-like Cell Subpopulation of Multiple Myeloma

Morgenroth, A., Vogg, A. T., Zlatopolskiy, B. D., Siluschek, M., Oedekoven, C. & Mottaghy, F. M., 1 Jan 2014, In : Molecular Cancer Therapeutics. 13, 1, p. 144-153 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Changes in 5-HT2A Receptor Expression in Untreated, de novo Patients with Parkinson's Disease

Melse, M., Tan, S. K. H., Temel, Y., van Kroonenburgh, M. J. P. G. & Leentjens, A. F. G., 2014, In : Journal of Parkinsons Disease. 4, 2, p. 283-287

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Comparison of [18 F]FDG PET/CT and MRI in the diagnosis of active osteomyelitis

Demirev, A., Weijers, R., Geurts, J., Mottaghy, F., Walenkamp, G. & Brans, B., 1 Jan 2014, In : Skeletal Radiology. 43, 5, p. 665-672

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Extent of disease activity assessed by 18F-FDG PET/CT in a Dutch sarcoidosis population

Cremers, J. P., van Kroonenburgh, M. J., Mostard, R. L., Voo, S. A., Wijnen, P. A., Koek, G. H. & Drent, M., 1 Jan 2014, In : Sarcoidosis Vasculitis and Diffuse Lung Diseases. 31, 1, p. 37-45

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Frequent extreme cold exposure and brown fat and cold-induced thermogenesis: A study in a monozygotic twin

Vosselman, M. J., Vijgen, G. H., Kingma, B. R., Brans, B. & van Marken Lichtenbelt, W. D., 11 Jul 2014, In : PLOS ONE. 9, 7, 8 p., e101653.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

In Vivo Molecular Imaging of Apoptosisand Necrosis in Atherosclerotic PlaquesUsing MicroSPECT-CT and MicroPET-CT Imaging

De Saint-Hubert, M., Bauwens, M., Deckers, N., Drummen, M., Douma, K., Granton, P., Hendrikx, G., Kusters, D., Bucerius, J., Reutelingsperger, C. P. M. & Mottaghy, F. M., 1 Jan 2014, In : Molecular Imaging and Biology. 16, 2, p. 246-254

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Molecular imaging of apoptosis for early prediction of therapy efficiency.

De Saint-Hubert, M., Bauwens, M. & Mottaghy, F. M., 1 Jan 2014, In : Current Pharmaceutical Design. 20, 14, p. 2319-2328

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Molecular imaging of brown adipose tissue in health and disease

Bauwens, M., Wierts, R., van Royen, B., Bucerius, J., Backes, W., Mottaghy, F. & Brans, B., Apr 2014, In : European Journal of Nuclear Medicine and Molecular Imaging. 41, 4, p. 776-791 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Negative (18)F-2-fluorodeoxyglucose PET/CT predicts good cancer specific survival in patients with a suspicion of recurrent ovarian cancer

Hebel, C. B., Behrendt, F. F., Heinzel, A., Krohn, T., Mottaghy, F. M., Bauerschlag, D. O. & Verburg, F. A., Mar 2014, In : European Journal of Radiology. 83, 3, p. 463-467 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Nondestructive monitoring of tissue-engineered constructs

Frese, J., Morgenroth, A., Mertens, M. E., Koch, S., Rongen, L., Vogg, A. T., Zlatopolskiy, B. D., Neumaier, B., Gesche, V. N., Lammers, T., Schmitz-Rode, T., Mela, P., Jockenhoevel, S., Mottaghy, F. M. & Kiessling, F., 1 Jan 2014, In : Biomedizinische Technik. 59, 2, p. 165-175

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Nuclear medicine training and practice in Germany

Freudenberg, L. S., Hellwig, D., Mottaghy, F. M., Franzius, C. & Gotthardt, M., 1 Jan 2014, In : European Journal of Nuclear Medicine and Molecular Imaging. 41, 1, p. 187-190 4 p.

Research output: Contribution to journalEditorialAcademicpeer-review

2 Citations (Scopus)

Prognostic Relevance of 18F-FDG PET/CT in Carcinoma of Unknown Primary

Breuer, N., Behrendt, F. F., Heinzel, A., Mottaghy, F. M., Palmowski, M. & Verburg, F. A., 1 Jan 2014, In : Clinical Nuclear Medicine. 39, 2, p. 131-135

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Protein kinase-D1 overexpression prevents lipid-induced cardiac insulin resistance

Dirkx, E., van Eys, G. J. J. M., Schwenk, R. W., Steinbusch, L. K. M., Hoebers, N., Coumans, W. A., Peters, T., Janssen, B. J., Brans, B., Vogg, A. T., Neumann, D., Glatz, J. F. C. & Luiken, J. J. F. P., Nov 2014, In : Journal of Molecular and Cellular Cardiology. 76, p. 208-217

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

The Longitudinal Assessment of Osteomyelitis Development by Molecular Imaging in a Rabbit Model

Odekerken, J. C. E., Walenkamp, G. H. I. M., Brans, B. T., Welting, T. J. M. & Arts, J. J. C., 1 Jan 2014, In : BioMed Research International. 2014, 10 p., 424652.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Thyroid nodules with indeterminate cytology: molecular imaging with Tc-99m-methoxyisobutylisonitrile (MIBI) is more cost-effective than the AfirmaA (R) gene expression classifier

Heinzel, A., Muller, D., Behrendt, F. F., Giovanella, L., Mottaghy, F. M. & Verburg, F. A., Aug 2014, In : European Journal of Nuclear Medicine and Molecular Imaging. 41, 8, p. 1497-1500 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)
2013

124I PET/CT in the pretherapeutic staging of differentiated thyroid carcinoma: comparison with posttherapy 131I SPECT/CT

de Pont, C., Halders, S., Bucerius, J., Mottaghy, F. & Brans, B., 1 Jan 2013, In : European Journal of Nuclear Medicine and Molecular Imaging. 40, 5, p. 693-700

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)