MaCSBio | Faculty of Health, Medicine and Life Sciences

Research output

Research output per year 2012 2016 2017 2018 2019 2020 2021 2024

• 321 Article
• 26 (Systematic) Review article
• 24 Conference Abstract/Poster in journal
• 22 Doctoral Thesis
• 35 More
  • 10 Erratum / corrigendum / retractions
  • 8 Editorial
  • 5 Comment/Letter to the editor
  • 3 Conference article in proceeding
  • 2 Inaugural speech
  • 2 Chapter
  • 1 Report
  • 1 Abstract
  • 1 Poster
  • 1 Software
  • 1 Preprint

Research output per year

Research output per year

Search results

• 2016

  ADAMTS genes and the risk of cerebral aneurysm

  Arning, A., Jeibmann, A., Koehnemann, S., Brokinkel, B., Ewelt, C., Berger, K., Wellmann, J., Nowak-Goettl, U., Stummer, W., Stoll, M. & Holling, M., Aug 2016, In: Journal of Neurosurgery. 125, 2, p. 269-274

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma

  Rieswijk, L., Claessen, S. M. H., Bekers, O., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T., Kleinjans, J. C. S. & van Breda, S. G. J., 28 Mar 2016, In: Toxicology. 350, p. 31-39 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• A roadmap to improve the quality of atrial fibrillation management: proceedings from the fifth Atrial Fibrillation Network/European Heart Rhythm Association consensus conference

  Kirchhof, P., Breithardt, G., Bax, J., Benninger, G., Blomstrom-Lundqvist, C., Boriani, G., Brandes, A., Brown, H., Brueckmann, M., Calkins, H., Calvert, M., Christoffels, V., Crijns, H., Dobrev, D., Ellinor, P., Fabritz, L., Fetsch, T., Freedman, S. B., Gerth, A., Goette, A., & 51 othersGuasch, E., Hack, G., Haegeli, L., Hatem, S., Haeusler, K. G., Heidbuechel, H., Heinrich-Nols, J., Hidden-Lucet, F., Hindricks, G., Juul-Moeller, S., Kaeaeb, S., Kappenberger, L., Kespohl, S., Kotecha, D., Lane, D. A., Leute, A., Lewalter, T., Meyer, R., Mont, L., Muenzel, F., Nabauer, M., Nielsen, J. C., Oeff, M., Oldgren, J., Oto, A., Piccini, J. P., Pilmeyer, A., Potpara, T., Ravens, U., Reinecke, H., Rostock, T., Rustige, J., Savelieva, I., Schnabel, R., Schotten, U., Schwichtenberg, L., Sinner, M. F., Steinbeck, G., Stoll, M., Tavazzi, L., Themistoclakis, S., Tse, H. F., Van Gelder, I. C., Vardas, P. E., Varpula, T., Vincent, A., Werring, D., Willems, S., Ziegler, A., Lip, G. Y. H. & Camm, A. J., 1 Jan 2016, In: EP Europace. 18, 1, p. 37-50

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Association of the IGF1 gene with fasting insulin levels

  Willems, S. M., Cornes, B. K., Brody, J. A., Morrison, A. C., Lipovich, L., Dauriz, M., Chen, Y., Liu, C-T., Rybin, D. V., Gibbs, R. A., Muzny, D., Pankow, J. S., Psaty, B. M., Boerwinkle, E., Rotter, J. I., Siscovick, D. S., Vasan, R. S., Kaplan, R. C., Isaacs, A., Dupuis, J., & 2 othersvan Duijn, C. M. & Meigs, J. B., Sept 2016, In: European Journal of Human Genetics. 24, 9, p. 1337-1343

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Biological marks of early-life socioeconomic experience is detected in the adult inflammatory transcriptome

  Castagne, R., Kelly-Irving, M., Campanella, G., Guida, F., Krogh, V., Palli, D., Panico, S., Sacerdote, C., Tumino, R., Kleinjans, J., de Kok, T., Kyrtopoulos, S. A., Lang, T., Stringhini, S., Vermeulen, R., Vineis, P., Delpierre, C. & Chadeau-Hyam, M., 9 Dec 2016, In: Scientific Reports. 6, 38705 .

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Comment: The FAIR Guiding Principles for scientific data management and stewardship

  Wilkinson, M. D., Dumontier, M., Aalbersberg, IJ. J., Appleton, G., Axton, M., Baak, A., Blomberg, N., Boiten, J-W., Santos, L. B. D. S., Bourne, P. E., Bouwman, J., Brookes, A. J., Clark, T., Crosas, M., Dillo, I., Dumon, O., Edmunds, S., Evelo, C. T., Finkers, R., Gonzalez-Beltran, A., & 33 othersGray, A. J. G., Groth, P., Goble, C., Grethe, J. S., Heringa, J., 't Hoen, P. A. C., Hooft, R., Kuhn, T., Kok, R., Kok, J., Lusher, S. J., Martone, M. E., Mons, A., Packer, A. L., Persson, B., Rocca-Serra, P., Roos, M., van Schaik, R., Sansone, S-A., Schultes, E., Sengstag, T., Slater, T., Strawn, G., Swertz, M. A., Thompson, M., van der Lei, J., van Mulligen, E., Velterop, J., Waagmeester, A., Wittenburg, P., Wolstencroft, K., Zhao, J. & Mons, B., 15 Mar 2016, In: Scientific data. 3, 9 p., 160018.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Consumer attitude and purchase intention towards processed meat products with natural compounds and a reduced level of nitrite

  Hung, Y., de Kok, T. M. & Verbeke, W., Nov 2016, In: Meat Science. 121, p. 119-126

  Research output: Contribution to journal › Article › Academic › peer-review

• Cytokine production capacity in depression and anxiety

  Vogelzangs, N., de Jonge, P., Smit, J. H., Bahn, S. & Penninx, B. W., 31 May 2016, In: Translational Psychiatry. 6, 5, p. e825 9 p., 825.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Diabetes mellitus type 2 and subsite-specific colorectal cancer risk in men and women: results from the Netherlands Cohort Study on diet and cancer

  de Kort, S., Simons, C. C. J. M., van den Brandt, P. A., Goldbohm, R. A., Arts, I. C. W., de Bruine, A. P., Janssen - Heijnen, M., Sanduleanu, S., Masclee, A. A. M. & Weijenberg, M. P., Aug 2016, In: European Journal of Gastroenterology & Hepatology. 28, 8, p. 896-903 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  79 Downloads (Pure)

• Differences in Strength and Timing of the mtDNA Bottleneck between Zebrafish Germline and Non-germline Cells

  Otten, A. B. C., Theunissen, T. E. J., Derhaag, J. G., Lambrichs, E. H., Boesten, I. B. W., Winandy, M., van Montfoort, A. P. A., Tarbashevich, K., Raz, E., Gerards, M., Vanoevelen, J. M., van den Bosch, B. J. C., Muller, M. & Smeets, H. J. M., 19 Jul 2016, In: Cell Reports. 16, 3, p. 622-630 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps

  Iotchkova, V., Huang, J., Morris, J. A., Jain, D., Barbieri, C., Walter, K., Min, J. L., Chen, L., Astle, W., Cocca, M., Deelen, P., Elding, H., Farmaki, A-E., Franklin, C. S., Franberg, M., Gaunt, T. R., Hofman, A., Jiang, T., Kleber, M. E., Lachance, G., & 47 othersLuan, J., Malerba, G., Matchan, A., Mead, D., Memari, Y., Ntalla, I., Panoutsopoulou, K., Pazoki, R., Perry, J. R. B., Rivadeneira, F., Sabater-Lleal, M., Sennblad, B., Shin, S-Y., Southam, L., Traglia, M., van Dijk, F., van Leeuwen, E. M., Zaza, G., Zhang, W., Amin, N., Butterworth, A., Chambers, J. C., Dedoussis, G., Dehghan, A., Franco, O. H., Franke, L., Frontini, M., Gambaro, G., Gasparini, P., Hamsten, A., Issacs, A., Kooner, J. S., Kooperberg, C., Langenberg, C., Marz, W., Scott, R. A., Swertz, M. A., Toniolo, D., Uitterlinden, A. G., van Duijn, C. M., Watkins, H., Zeggini, E., Maurano, M. T., Timpson, N. J., Reiner, A. P., Auer, P. L. & Soranzo, N., Nov 2016, In: Nature Genetics. 48, 11, p. 1303-1312

  Research output: Contribution to journal › Article › Academic › peer-review

• Discriminative Ability of Plasma Branched-Chain Amino Acid Levels for Glucose Intolerance in Families At Risk for Type 2 Diabetes

  Jainandunsing, S., Wattimena, J. L. D., Verhoeven, A. J. M., Langendonk, J. G., Rietveld, T., Isaacs, A. J., Sijbrands, E. J. G. & de Rooij, F. W. M., 1 Apr 2016, In: Metabolic syndrome and related disorders. 14, 3, p. 175-181

  Research output: Contribution to journal › Article › Academic › peer-review

• Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study

  Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Hoffmann-Petersen, I. T., Thiel, S., Stehouwer, C. D. A. & van Greevenbroek, M. M. J., Jun 2016, In: Arteriosclerosis Thrombosis and Vascular Biology. 36, 6, p. 1278-1285 28 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• DNA methylation in an engineered heart tissue model of cardiac hypertrophy: common signatures and effects of DNA methylation inhibitors

  Stenzig, J., Hirt, M. N., Loeser, A., Bartholdt, L. M., Hensel, J-T., Werner, T. R., Riemenschneider, M., Indenbirken, D., Guenther, T., Mueller, C. P., Huebner, N., Stoll, M. & Eschenhagen, T., Jan 2016, In: Basic Research in Cardiology. 111, 1, 9.

  Research output: Contribution to journal › Article › Academic › peer-review

• Early Life Antibiotic Exposure and Weight Development in Children

  Mbakwa, C. A., Scheres, L., Penders, J., Mommers, M., Thijs, C. & Arts, I. C. W., Sept 2016, In: The Journal of Pediatrics. 176, p. 105-113.e2 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  58 Downloads (Pure)

• Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis

  Zweers, S. J., Shiryaev, A., Komuta, M., Vesterhus, M., Hov, J. R., Perugorria, M. J., de Waart, D. R., Chang, J. C., Tol, S., Te Velde, A. A., de Jonge, W. J., Banales, J. M., Roskams, T., Beuers, U., Karlsen, T. H., Jansen, P. L. M. & Schaap, F. G., Sept 2016, In: Liver International. 36, 9, p. 1370-1377 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Estimating real cell size distribution from cross-section microscopy imaging

  Lenz, M., Roumans, N. J. T., Vink, R. G., van Baak, M. A., Mariman, E. C. M., Arts, I. C. W., de Kok, T. & Ertaylan, G., 1 Sept 2016, In: Bioinformatics. 32, 17, p. i396-i404 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Expert consensus document: Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment

  Fabritz, L., Guasch, E., Antoniades, C., Bardinet, I., Benninger, G., Betts, T. R., Brand, E., Breithardt, G., Bucklar-Suchankova, G., Camm, A. J., Cartlidge, D., Casadei, B., Chua, W. W., Crijns, H., Deeks, J., Hatem, S., Hidden-Lucet, F., Kääb, S., Maniadakis, N., Martin, S., & 11 othersMont, L., Reinecke, H., Sinner, M. F., Schotten, U., Southwood, T., Stoll, M., Vardas, P., Wakili, R., West, A., Ziegler, A. & Kirchhof, P., Apr 2016, In: Nature Reviews Cardiology. 13, 4, p. 230-237 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans

  Evans, D. S., Avery, C. L., Nalls, M. A., Li, G., Barnard, J., Smith, E. N., Tanaka, T., Butler, A. M., Buxbaum, S. G., Alonso, A., Arking, D. E., Berenson, G. S., Bis, J. C., Buyske, S., Carty, C. L., Chen, W., Chung, M. K., Cummings, S. R., Deo, R., Eaton, C. B., & 41 othersFox, E. R., Heckbert, S. R., Heiss, G., Hindorff, L. A., Hsueh, W-C., Isaacs, A., Jamshidi, Y., Kerr, K. F., Liu, F., Liu, Y., Lohman, K. K., Magnani, J. W., Maher, J. F., Mehra, R., Meng, Y. A., Musani, S. K., Newton-Cheh, C., North, K. E., Psaty, B. M., Redline, S., Rotter, J. I., Schnabel, R. B., Schork, N. J., Shohet, R. V., Singleton, A. B., Smith, J. D., Soliman, E. Z., Srinivasan, S. R., Taylor, H. A. . J., Van Wagoner, D. R., Wilson, J. G., Young, T., Zhang, Z-M., Zonderman, A. B., Evans, M. K., Ferrucci, L., Murray, S. S., Tranah, G. J., Whitsel, E. A., Reiner, A. P. & Sotoodehnia, N., 1 Oct 2016, In: Human Molecular Genetics. 25, 19, p. 4350-4368

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

  Pattaro, C., Teumer, A., Gorski, M., Chu, A. Y., Li, M., Mijatovic, V., Garnaas, M., Tin, A., Sorice, R., Li, Y., Taliun, D., Olden, M., Foster, M., Yang, Q., Chen, M-H., Pers, T. H., Johnson, A. D., Ko, Y-A., Fuchsberger, C., Tayo, B., & 31 othersNalls, M., Feitosa, M. F., Isaacs, A., Dehghan, A., d'Adamo, P., Adeyemo, A., Dieffenbach, A. K., Zonderman, A. B., Nolte, I. M., van der Most, P. J., Wright, A. F., Shuldiner, A. R., Morrison, A. C., Hofman, A., Smith, A. V., Dreisbach, A. W., Franke, A., Uitterlinden, A. G., Metspalu, A., Tonjes, A., Lupo, A., Robino, A., Johansson, A., Demirkan, A., Kollerits, B., Freedman, B. I., Ponte, B., Oostra, B. A., Paulweber, B., Kraemer, B. K. & Author collaboration, Jan 2016, In: Nature Communications. 7, 19 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genetic variants in RBFOX3 are associated with sleep latency

  Amin, N., Allebrandt, K. V., van der Spek, A., Müller-Myhsok, B., Hek, K., Teder-Laving, M., Hayward, C., Esko, T., van Mill, J. G., Mbarek, H., Watson, N. F., Melville, S. A., Del Greco, F. M., Byrne, E. M., Oole, E., Kolcic, I., Chen, T-H., Evans, D. S., Coresh, J., Vogelzangs, N., & 54 othersKarjalainen, J., Willemsen, G., Gharib, S. A., Zgaga, L., Mihailov, E., Stone, K. L., Campbell, H., Brouwer, R. W., Demirkan, A., Isaacs, A., Dogas, Z., Marciante, K. D., Campbell, S., Borovecki, F., Luik, A. I., Li, M., Hottenga, J. J., Huffman, J. E., van den Hout, M. C., Cummings, S. R., Aulchenko, Y. S., Gehrman, P. R., Uitterlinden, A. G., Wichmann, H-E., Müller-Nurasyid, M., Fehrmann, R. S., Montgomery, G. W., Hofman, A., Kao, W. H. L., Oostra, B. A., Wright, A. F., Vink, J. M., Wilson, J. F., Pramstaller, P. P., Hicks, A. A., Polasek, O., Punjabi, N. M., Redline, S., Psaty, B. M., Heath, A. C., Merrow, M., Tranah, G. J., Gottlieb, D. J., Boomsma, D. I., Martin, N. G., Rudan, I., Tiemeier, H., van IJcken, W. F., Penninx, B. W., Metspalu, A., Meitinger, T., Franke, L., Roenneberg, T. & van Duijn, C. M., Oct 2016, In: European Journal of Human Genetics. 24, 10, p. 1488-1495 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

  Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., Berndt, S. I., Bidlingmaier, M., Broer, L., Cappola, A., Ceda, G. P., Chanock, S., Chen, M-H., Chen, T. C., Chen, Y-D. I., Chung, J., Miglianico, F. D. G., Eriksson, J., Ferrucci, L., Friedrich, N., & 66 othersGnewuch, C., Goodarzi, M. O., Grarup, N., Guo, T., Hammer, E., Hayes, R. B., Hicks, A. A., Hofman, A., Houwing-Duistermaat, J. J., Hu, F., Hunter, D. J., Husemoen, L. L., Isaacs, A., Jacobs, K. B., Janssen, J. A. M. J. L., Jansson, J-O., Jehmlich, N., Johnson, S., Juul, A., Karlsson, M., Kilpelainen, T. O., Kovacs, P., Kraft, P., Li, C., Linneberg, A., Liu, Y., Loos, R. J. F., Lorentzon, M., Lu, Y., Maggio, M., Magi, R., Meigs, J., Mellstrom, D., Nauck, M., Newman, A. B., Pollak, M. N., Pramstaller, P. P., Prokopenko, I., Psaty, B. M., Reincke, M., Rimm, E. B., Rotter, J. I., Saint Pierre, A., Schurmann, C., Seshadri, S., Sjogren, K., Slagboom, P. E., Strickler, H. D., Stumvoll, M., Suh, Y., Sun, Q., Zhang, C., Svensson, J., Tanaka, T., Tare, A., Toenjes, A., Uh, H-W., van Duijn, C. M., van Heemst, D., Vandenput, L., Vasan, R. S., Voelker, U., Willems, S. M., Ohlsson, C., Wallaschofski, H. & Kaplan, R. C., Oct 2016, In: Aging Cell. 15, 5, p. 811-824

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

  Kilpelainen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, A. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikainen, L-P., Eriksson, J., & 157 othersHenneman, P., Lahti, J., Tanaka, T., Luan, J., Del Greco M, F., Pasko, D., Renstrom, F., Willems, S. M., Mahajan, A., Rose, L. M., Guo, X., Liu, Y., Kleber, M. E., Perusse, L., Gaunt, T., Ahluwalia, T. S., Sung, Y. J., Ramos, Y. F., Amin, N., Amuzu, A., Barroso, I., Bellis, C., Blangero, J., Buckley, B. M., Bohringer, S., Chen, Y-D. I., de Craen, A. J. N., Crosslin, D. R., Dale, C. E., Dastani, Z., Day, F. R., Deelen, J., Delgado, G. E., Demirkan, A., Finucane, F. M., Ford, I., Garcia, M. E., Gieger, C., Gustafsson, S., Hallmans, G., Hankinson, S. E., Havulinna, A. S., Herder, C., Hernandez, D., Hicks, A. A., Hunter, D. J., Illig, T., Ingelsson, E., Ioan-Facsinay, A., Jansson, J-O., Jenny, N. S., Jorgensen, M. E., Jorgensen, T., Karlsson, M., Koenig, W., Kraft, P., Kwekkeboom, J., Laatikainen, T., Ladwig, K-H., LeDuc, C. A., Lowe, G., Lu, Y., Marques-Vidal, P., Meisinger, C., Menni, C., Morris, A. P., Myers, R. H., Mannisto, S., Nalls, M. A., Paternoster, L., Peters, A., Pradhan, A. D., Rankinen, T., Rasmussen-Torvik, L. J., Rathmann, W., Rice, T. K., Richards, J. B., Ridker, P. M., Sattar, N., Savage, D. B., Soderberg, S., Timpson, N. J., Vandenput, L., van Heemst, D., Uh, H-W., Vohl, M-C., Walker, M., Wichmann, H-E., Widen, E., Wood, A. R., Yao, J., Zeller, T., Zhang, Y., Meulenbelt, I., Kloppenburg, M., Astrup, A., Sorensen, T. I. A., Sarzynski, M. A., Rao, D. C., Jousilahti, P., Vartiainen, E., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Kajantie, E., Osmond, C., Palotie, A., Eriksson, J. G., Heliovaara, M., Knekt, P. B., Koskinen, S., Jula, A., Perola, M., Huupponen, R. K., Viikari, J. S., Kahonen, M., Lehtimaki, T., Raitakari, O. T., Mellstrom, D., Lorentzon, M., Casas, J. P., Bandinelli, S., Maerz, W., Isaacs, A., van Dijk, K. W., van Duijn, C. M., Harris, T. B., Bouchard, C., Allison, M. A., Chasman, D. I., Ohlsson, C., Lind, L., Scott, R. A., Langenberg, C., Wareham, N. J., Ferrucci, L., Frayling, T. M., Pramstaller, P. P., Borecki, I. B., Waterworth, D. M., Bergmann, S., Waeber, G., Vollenweider, P., Vestergaard, H., Hansen, T., Pedersen, O., Hu, F. B., Slagboom, P. E., Grallert, H., Spector, T. D., Jukema, J. W., Klein, R. J., Schadt, E. E., Franks, P. W., Lindgren, C. M., Leibel, R. L. & Loos, R. J. F., Feb 2016, In: Nature Communications. 7, 10494.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Hepatocellular carcinoma in cirrhotic versus noncirrhotic livers: results from a large cohort in the Netherlands

  van der Meer, S., van Erpecum, K. J., Sprengers, D., Coenraad, M. J., Klumpen, H. J., Jansen, P. L. M., JN, I. J., Verheij, J., van Nieuwkerk, C. M., Siersema, P. D. & De Man, RA., Mar 2016, In: European Journal of Gastroenterology & Hepatology. 28, 3, p. 352-359 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Hepatocellular carcinoma in noncirrhotic livers is associated with steatosis rather than steatohepatitis: potential implications for pathogenesis

  van Meer, S., van Erpecum, K. J., Sprengers, D., Klumpen, H-J., Jansen, P., Ijzermans, J. N. M., Siersema, P. D., de Man, R. A. & Verheij, J., Aug 2016, In: European Journal of Gastroenterology & Hepatology. 28, 8, p. 955-962

  Research output: Contribution to journal › Article › Academic › peer-review

• Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers

  Claes, G. R. F., van Tienen, F. H. J., Lindsey, P., Krapels, I. P. C., van den Enden, A., Hoos, M., Barrois, Y. E. G., Janssen, J., Paulussen, A. D. C., Sels, J-W. E. M., Kuijpers, S. H. H., van Tintelen, J. P., van den Berg, M. P., Heesen, W. F., Garcia-Pavia, P., Perrot, A., Christiaans, I., Salemink, S., Marcelis, C. L. M., Smeets, B., & 3 othersBrunner, H. G., Volders, P. G. A. & van den Wijngaard, A., 14 Jun 2016, In: European Heart Journal. 37, 23, p. 1815-1822

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Inferring causal molecular networks: empirical assessment through a community-based effort

  The HPN-Dream Consortium, Bohler, A., Evelo, C. & Kutmon, M., Apr 2016, In: Nature Methods. 13, 4, p. 310-318 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis

  Wolters, J. E. J., van Herwijnen, M. H. M., Theunissen, D. H. J., Jennen, D. G. J., Van den Hof, W. F. P. M., de Kok, T., Schaap, F. G., van Breda, S. G. J. & Kleinjans, J. C. S., Dec 2016, In: Chemical Research in Toxicology. 29, 12, p. 2164-2174

  Research output: Contribution to journal › Article › Academic › peer-review

• Intensive lifestyle treatment for non-alcoholic fatty liver disease in children with severe obesity: inpatient versus ambulatory treatment

  Koot, B. G. P., van der Baan-Slootweg, O. H., Vinke, S., Bohte, A. E., Tamminga-Smeulders, C. L. J., Jansen, P. L. M., Stoker, J. & Benninga, M. A., Jan 2016, In: International Journal of Obesity. 40, 1, p. 51-57

  Research output: Contribution to journal › Article › Academic › peer-review

• Long non-coding RNA Databases in Cardiovascular Research

  Rühle, F. & Stoll, M., Aug 2016, In: Genomics, Proteomics and Bioinformatics. 14, 4, p. 191–199 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

  van Leeuwen, E. M., Sabo, A., Bis, J. C., Huffman, J. E., Manichaikul, A., Smith, A. V., Feitosa, M. F., Demissie, S., Joshi, P. K., Duan, Q., Marten, J., van Klinken, J. B., Surakka, I., Nolte, I. M., Zhang, W., Mbarek, H., Li-Gao, R., Trompet, S., Verweij, N., Evangelou, E., & 78 othersLyytikainen, L-P., Tayo, B. O., Deelen, J., van der Most, P. J., van der Laan, S. W., Arking, D. E., Morrison, A., Dehghan, A., Franco, O. H., Hofman, A., Rivadeneira, F., Sijbrands, E. J., Uitterlinden, A. G., Mychaleckyj, J. C., Campbell, A., Hocking, L. J., Padmanabhan, S., Brody, J. A., Rice, K. M., White, C. C., Harris, T., Isaacs, A., Campbell, H., Lange, L. A., Rudan, I., Kolcic, I., Navarro, P., Zemunik, T., Salomaa, V., Kooner, A. S., Kooner, J. S., Lehne, B., Scott, W. R., Tan, S-T., de Geus, E. J., Milaneschi, Y., Penninx, B. W. J. H., Willemsen, G., de Mutsert, R., Ford, I., Gansevoort, R. T., Segura-Lepe, M. P., Raitakari, O. T., Viikari, J. S., Nikus, K., Forrester, T., McKenzie, C. A., de Craen, A. J. M., de Ruijter, H. M., Pasterkamp, G., Snieder, H., Oldehinkel, A. J., Slagboom, P. E., Cooper, R. S., Kahonen, M., Lehtimaki, T., Elliott, P., van der Harst, P., Jukema, J. W., Mook-Kanamori, D. O., Boomsma, D. I., Chambers, J. C., Swertz, M., Ripatti, S., van Dijk, K. W., Vitart, V., Polasek, O., Hayward, C., Wilson, J. G., Wilson, J. F., Gudnason, V., Rich, S. S., Psaty, B. M., Borecki, I. B., Boerwinkle, E., Rotter, J. I., Cupples, L. A. & van Duijn, C. M., Jul 2016, In: Journal of Medical Genetics. 53, 7, p. 441-449

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Mitochondrial DNA sequence characteristics modulate the size of the genetic bottleneck

  Wilson, I. J., Carling, P. J., Alston, C. L., Floros, V. I., Pyle, A., Hudson, G., Sallevelt, S. C. E. H., Lamperti, C., Carelli, V., Bindoff, L. A., Samuels, D. C., Wonnapinij, P., Zeviani, M., Taylor, R. W., Smeets, H. J. M., Horvath, R. & Chinnery, P. F., 1 Mar 2016, In: Human Molecular Genetics. 25, 5, p. 1031-1041

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

  Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dorr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikainen, L-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., Smith, A. V., & 80 othersVojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y-D. I., Cupples, L. A., de Jong, P. A., de Koning, H., de Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Isgum, I., Jukema, J. W., Kahonen, M., Kardia, S. L. R., Kral, B. G., Launer, L. J., Massaro, J., Mehran, R., Mitchell, B. D., Jr, T. H. M., de Mutsert, R., Newman, A. B., Nguyen, K., North, K. E., O'Connell, J. R., Oudkerk, M., Pankow, J. S., Peloso, G. M., Post, W., Province, M. A., Raffield, L. M., Raitakari, O. T., Reilly, D. F., Rivadeneira, F., Rosendaal, F., Sartori, S., Taylor, K. D., Teumer, A., Trompet, S., Turner, S. T., Uitterlinden, A. G., Vaidya, D., van der Lugt, A., Volker, U., Wardlaw, J. M., Wassel, C. L., Weiss, S., Wojczynski, M. K., Becker, D. M., Becker, L. C., Boerwinkle, E., Bowden, D. W., Deary, I. J., Dehghan, A., Felix, S. B., Gudnason, V., Lehtimaki, T., Mathias, R., Mook-Kanamori, D. O., Psaty, B. M., Rader, D. J., Rotter, J. I., Wilson, J. G., van Duijn, C. M., Volzke, H., Kathiresan, S., Peyser, P. A. & O'Donnell, C. J., Dec 2016, In: Circulation : Cardiovascular Genetics. 9, 6, p. 511-520

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• New insights in Rett syndrome using pathway analysis for transcriptomics data

  Ehrhart, F., Steinbusch - Coort, S., Cirillo, E., Smeets, E., Evelo, C. T. & Curfs, L., Sept 2016, In: Wiener Medizinische Wochenschrift. 166, 11, p. 346-352 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• No Fabry Disease in Patients Presenting with Isolated Small Fiber Neuropathy

  de Greef, B. T. A., Hoeijmakers, J. G. J., Wolters, E. E., Smeets, H. J. M., van den Wijngaard, A., Merkies, I. S. J., Faber, K. & Gerrits, M. M., 11 Feb 2016, In: PLOS ONE. 11, 2, e0148316.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns

  Digles, D., Zdrazil, B., Neefs, J. -M., Van Vlijmen, H., Herhaus, C., Caracoti, A., Brea, J., Roibas, B., Loza, M. I., Queralt-Rosinach, N., Furlong, L. I., Gaulton, A., Bartek, L., Senger, S., Chichester, C., Engkvist, O., Evelo, C. T., Franklin, N. I., Marren, D., Ecker, G. F., & 1 othersJacoby, E., 2016, In: Medchemcomm. 7, 6, p. 1237-1244

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  Open Access

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• Pathogenic CWF19L1 variants as a novel cause of autosomal recessive cerebellar ataxia and atrophy

  Nguyen, M., Boesten, I. B. W., Hellebrekers, D. M. E. I., Vanoevelen, J., Kamps, R., de Koning, B., de Coo, I. F. M., Gerards, M. & Smeets, H. J. M., Apr 2016, In: European Journal of Human Genetics. 24, 4, p. 619-622 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Pathway-based variant enrichment analysis on the example of dilated cardiomyopathy

  Backes, C., Meder, B., Lai, A., Stoll, M., Ruehle, F., Katus, H. A. & Keller, A., Jan 2016, In: Human Genetics. 135, 1, p. 31-40

  Research output: Contribution to journal › Article › Academic › peer-review

• Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia

  Adriaens, M. E., Prickaerts, P., Chan-Seng-Yue, M., van den Beucken, T., Dahlmans, V. E. H., Eijssen, L. M., Beck, T., Wouters, B. G., Voncken, W. & Evelo, C. T. A., 1 Nov 2016, In: Epigenetics & Chromatin. 9, 48.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Reactome from a WikiPathways Perspective

  Bohler, A., Wu, G., Kutmon, M., Pradhana, L. A., Steinbusch - Coort, S., Hanspers, K., Haw, R., Pico, A. R. & Evelo, C. T., May 2016, In: PLoS Computational Biology. 12, 5, e1004941.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs

  Ricano-Ponce, I., Zhernakova, D. V., Deelen, P., Luo, O., Li, X., Isaacs, A., Karjalainen, J., Di Tommaso, J., Borek, Z. A., Zorro, M. M., Gutierrez-Achury, J., Uitterlinden, A. G., Hofman, A., van Meurs, J., Netea, M. G., Jonkers, I. H., Withoff, S., van Duijn, C. M., Li, Y., Ruan, Y., & 3 othersFranke, L., Wijmenga, C. & Kumar, V., Apr 2016, In: Journal of Autoimmunity. 68, p. 62-74

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Rett syndrome - biological pathways leading from MECP2 to disorder phenotypes

  Ehrhart, F., Steinbusch - Coort, S., Cirillo, E., Smeets, E., Evelo, C. T. & Curfs, L. M. G., 25 Nov 2016, In: Orphanet Journal of Rare Diseases. 11, 13 p., 158.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies

  Demirkan, A., Lahti, J., Direk, N., Viktorin, A., Lunetta, K. L., Terracciano, A., Nalls, M. A., Tanaka, T., Hek, K., Fornage, M., Wellmann, J., Cornelis, M. C., Ollila, H. M., Yu, L., Smith, J. A., Pilling, L. C., Isaacs, A., Palotie, A., Zhuang, W. V., Zonderman, A., & 37 othersFaul, J. D., Sutin, A., Meirelles, O., Mulas, A., Hofman, A., Uitterlinden, A., Rivadeneira, F., Perola, M., Zhao, W., Salomaa, V., Yaffe, K., Luik, A. I., Liu, Y., Ding, J., Lichtenstein, P., Landen, M., Widen, E., Weir, D. R., Llewellyn, D. J., Murray, A., Kardia, S. L. R., Eriksson, J. G., Koenen, K., Magnusson, P. K. E., Ferrucci, L., Mosley, T. H., Cucca, F., Oostra, B. A., Bennett, D. A., Paunio, T., Berger, K., Harris, T. B., Pedersen, N. L., Murabito, J. M., Tiemeier, H., van Duijn, C. M. & Raeikkoenen, K., Jun 2016, In: Psychological Medicine. 46, 8, p. 1613-1623

  Research output: Contribution to journal › Article › Academic › peer-review

• Specific MRI Abnormalities Reveal Severe Perrault Syndrome due to CLPP Defects

  Theunissen, T. E. J., Szklarczyk, R., Gerards, M., Hellebrekers, D. M. E. I., Mulder-Den Hartog, E. N. M., Vanoevelen, J., Kamps, R., de Koning, B., Rutledge, S. L., Schmitt-Mechelke, T., Van Berkel, C. G. M., van der Knaap, M. S., de Coo, I. F. M. & Smeets, H. J. M., 16 Nov 2016, In: Frontiers in Neurology. 7, 8 p., 203.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Stakeholder and consumer reactions towards innovative processed meat products: Insights from a qualitative study about nitrite reduction and phytochemical addition

  Hung, Y., Verbeke, W. & de Kok, T. M., Feb 2016, In: Food Control. 60, p. 690-698

  Research output: Contribution to journal › Article › Academic › peer-review

• The alternative complement pathway is longitudinally associated with adverse cardiovascular outcomes The CODAM study

  Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Stehouwer, C. D. A. & van Greevenbroek, M. M. J., Feb 2016, In: Thrombosis and Haemostasis. 115, 2, p. 446-457 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• The systems biology format converter

  Rodriguez, N., Pettit, J-B., Pezze, P. D., Li, L., Henry, A., van Iersel, M. P., Jalowicki, G., Kutmon, M., Natarajan, K. N., Tolnay, D., Stefan, M. I., Evelo, C. T. & Le Novere, N., 5 Apr 2016, In: BMC Bioinformatics. 17, 154.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

  Verweij, N., Leach, I. M., Isaacs, A., Arking, D. E., Bis, J. C., Pers, T. H., Van den Berg, M. E., Lyytikainen, L-P., Barnett, P., Wang, X., Soliman, E. Z., Van Duijn, C. M., Kahonen, M., Van Veldhuisen, D. J., Kors, J. A., Raitakari, O. T., Silva, C. T., Lehtimaki, T., Hillege, H. L., Hirschhorn, J. N., & 9 othersBoyer, L. A., Van Gilst, W. H., Alonso, A., Sotoodehnia, N., Eijgelsheim, M., De Boer, R. A., De Bakker, P. I. W., Franke, L. & Van der Harst, P., 15 May 2016, In: Human Molecular Genetics. 25, 10, p. 2093-2103

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources

  Waagmeester, A., Kutmon, M., Riutta, A., Miller, R., Willighagen, E. L., Evelo, C. T. & Pico, A. R., Jun 2016, In: PLoS Computational Biology. 12, 6, 11 p., e1004989.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• WikiPathways: capturing the full diversity of pathway knowledge

  Kutmon, M., Riutta, A., Nunes, N., Hanspers, K., Willighagen, E. L., Bohler, A., Melius, J., Waagmeester, A., Sinha, S. R., Miller, R., Coort, S. L., Cirillo, E., Smeets, B., Evelo, C. T. & Pico, A. R., 4 Jan 2016, In: Nucleic Acids Research. 44, D1, p. D488-D494 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access