Maastricht University

  • Minderbroedersberg4, MBB4-6

    6211 LK Maastricht

    Netherlands

Research Output

1960

Inhibition of enzymes by Atebrin

Hemker, H. C. & Hülsmann, W. C., 1960, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 44, p. 175-177 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1961

Dinitrophenol-induced ATPase of rat-liver mitochondria

Hemker, H. C. & Hülsmann, W. C., 18 Mar 1961, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 48, 1, p. 221-223 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

1962

A new application of the Clark oxygen electrode

Hemker, H. C., 16 Jul 1962, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 60, 3, p. 646-647 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Lipid solubility as a factor influencing the activity of uncoupling phenols

Hemker, H. C., 1962, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 63, 1, p. 46-54 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

1964

Behaviour of factors II, VII, IX and X in bleeding complications during long-term treatment with Coumarin

Loeliger, E. A., Hensen, A., Mattern, M. J. & Hemker, H. C., 1 Jan 1964, In : Thrombosis et diathesis haemorrhagica. 10, 3/4, p. 278-281 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Kwantitering in de bloedstolling

Hemker, H. C., 1 Jan 1964, In : Maandschrift voor kindergeneeskunde. 22, p. 503-511 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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The mode of action of dinitrophenols on the different phosphorylating steps

Hemker, H. C., 1964, In : Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 81, 1, p. 9-20 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

1965

Kinetic aspects of the interaction of blood clotting enzymes: I. Derivation of basic formulas

Hemker, H. C., Hemker, P. W. & Loeliger, E. A., 1 Jan 1965, In : Thrombosis et diathesis haemorrhagica. 13, 1-2, p. 155-175 21 p.

Research output: Contribution to journalArticleAcademicpeer-review

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The biological half-time of hageman factor

Veltkamp, J. J., Loeliger, E. A. & Hemker, H. C., 26 Mar 1965, In : Thrombosis et diathesis haemorrhagica. 13, 1/2, p. 1-7 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

File
1966

A double blind study of phenprocoumon prophylaxis after myocardial infarction

Hensen, A., Kroes, F., van Dyck, L. M., Fekkes, N., Hemker, H. C. & Loeliger, E. A., 1966, Pathogenesis and Treatment of Thromboembolic Diseases, including Coronary, Cerebral and Peripheral Thrombosis: International Symposium, Basle, Switzerland, August 29th-September 1st 1965. Duckert, F. (ed.). Stuttgart: F. K. Schattauer Verlag, p. 333-336 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Open Access
File
1967

A double-blind trial of long-term anticoagulant treatment after myocardial infarction

Loeliger, E. A., Hensen, A., Kroes, F., van Dijk, L. M., Fekkes, N., de Jonge, H. & Hemker, H. C., 1967, In : Journal of Internal Medicine. 182, 5, p. 549-566 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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Contact activation in the extrinsic blood clotting system

Altman, R. & Hemker, H. C., 1 Jan 1967, In : Thrombosis et diathesis haemorrhagica. 18, 3-4, p. 525-531 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Formation of prothrombin converting activity

Hemker, H. C., Esnouf, M. P., Hemker, P. W., Swart, A. C. W. & MacFarlane, R. G., 1 Jan 1967, In : Nature. 215, 5098, p. 248-251 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetic aspects of the interaction of blood-clotting enzymes: II. The relation between clotting time and plasma concentration in prothrombin-time estimations

Hemker, H. C., Siepel, T., Altman, R. & Loeliger, E. A., 1 Jan 1967, In : Thrombosis et diathesis haemorrhagica. 17, 3-4, p. 349-357 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Reaction sequence of blood coagulation

Hemker, H. C. & Kahn, M. J. P., 1 Jan 1967, In : Nature. 215, p. 1201-1202 2 p.

Research output: Contribution to journalArticleAcademicpeer-review

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The pathways of blood coagulation

Hemker, H. C., 1 Jan 1967, In : Folia medica neerlandica. 10, 4/5, p. 101-111 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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1968

Arvin: Een nieuw anticoagulans

Hemker, H. C. & Loeliger, E. A., 1968, In : Nederlands Tijdschrift voor Geneeskunde. 112, 43, p. 1958-1960 3 p.

Research output: Contribution to journalArticleAcademic

Open Access

Behandlung der Hämophilie B mit PPSB

Loeliger, E. A., Mattern, M. J., Hensen, A. & Hemker, H. C., Feb 1968, In : Blut. 16, p. 289-297 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Kinetic aspects of the interaction of blood clotting enzymes: III. Demonstration of an inhibitor of prothrombin conversion in vitamin K deficiency

Hemker, H. C., Veltkamp, J. J. & Loeliger, E. A., 1 Jan 1968, In : Thrombosis et diathesis haemorrhagica. 19, 3-4, p. 346-363 18 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetic aspects of the interaction of blood clotting enzymes: VI. Localization of the site of blood-coagulation inhibition by the protein induced by Vitamin K Absence (PIVKA)

Hemker, H. C. & Muller, A. D., 1 Jan 1968, In : Thrombosis et diathesis haemorrhagica. 20, 1-2, p. 78-87 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetic aspects of the interaction of blood clotting enzymes: V. The reaction mechanism of the extrinsic clotting system as revealed by the kinetics of one-stage estimations of coagulation enzymes

Hemker, H. C. & Muller, A. D., 1 Jan 1968, In : Thrombosis et diathesis haemorrhagica. 19, 3-4, p. 368-382 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetic aspects of the interaction of blood clotting enzymes: IV. Kinetics of competitive inhibition in clotting tests

Hemker, H. C. & Hemker, P. W., 1 Jan 1968, In : Thrombosis et diathesis haemorrhagica. 19, 3-4, p. 364-367 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Principles of the mode of action of coumarin congeners

Loeliger, E. A. & Hemker, H. C., 1 Jan 1968, Proceedings of the 3rd International Pharmacological Meeting: July 24-30, 1966. 1 ed. Oxford: Pergamon Press Ltd., Vol. 6. p. 13-24 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Open Access
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2 Downloads (Pure)

Protrombinetijden en Thrombotest bij antistollingsbehandeling

Loeliger, E. A. & Hemker, H. C., 30 Nov 1968, In : Nederlands Tijdschrift voor Geneeskunde. 112, 48, p. 2195-2198 4 p.

Research output: Contribution to journalArticleAcademic

Open Access
1969

Considerations on an international standard for the one-stage prothrombin time in the control of anticoagulant therapy

Loeliger, E. A. & Hemker, H. C., 1969, Plasma Fractions for the Treatment of Hemophilia: Anticoagulant Therapy: Standardization of Tests; Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis, Washington, D.C., U.S.A., December 1967. Brinkhous, K. M. (ed.). Stuttgart: F. K. Schattauer Verlag, p. 101-105 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Het reactiemechanisme van de bloedstolling

Hemker, H. C. & Haanen, C., Feb 1969, In : Nederlands Tijdschrift voor Geneeskunde. 113, 5, p. 203-210 8 p.

Research output: Contribution to journalArticleAcademic

Open Access

Studies on blood coagulation factor V: I. The interaction of salts of fatty acids and coagulation factors

Kahn, M. J. P. & Hemker, H. C., 1969, In : Thrombosis et diathesis haemorrhagica. 12, 3, p. 417-430 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

File

The kinetics of enzyme cascade systems: General kinetics of enzyme cascades

Hemker, H. C. & Hemker, P. W., 1 Jan 1969, In : Proceedings of the Royal Society of London, Series B, Biological sciences. 173, 1032, p. 411-420 10 p., H.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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1970

Les protéines dont la synthèse est induite par l'avitaminose K

Hemker, H. C., 1 Jan 1970, In : Nouvelle revue francaise d'hematologie. 10, 5, p. 645-652 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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3 Downloads (Pure)

Separation of blood coagulation factors II, VII, IX and X by cel filtration in the presence of Dextran blue

Swart, A. C. W. & Hemker, H. C., 29 Dec 1970, In : Biochimica et Biophysica Acta-general Subjects. 222, 3, p. 692-695 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Standardization in the laboratory control of oral anticoagulants

Loeliger, E. A. & Hemker, H. C., 1970, Vascular Factors and Thrombosis: Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis Bath, England, October 1969. Koller, F., Brinkhous, K. M., Biggs, R., Rodman, N. F. & Hinnom, S. (eds.). 1 ed. Stuttgart: F. K. Schattauer Verlag, p. 359-370 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Standardization of results obtained with different thromboplastin preparations

Loeliger, E. A., Taconis, W. K., Veltkamp, J. J. & Hemker, H. C., 1970, Fibrinogen: Structural, Metabolic and Patophysiologic Aspects: Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis, Princeton, New Jersey, U.S.A., November 24-26, 1968. Brinkhous, K. M. (ed.). Stuttgart: F. K. Schattauer Verlag, p. 369-376 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

File

Studies on blood coagulation factor V: IV. A partially purified factor V preparation from human plasma

Kahn, M. J. P. & Hemker, H. C., 1970, In : Coagulation. 3, 1, p. 63-66 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File

Twee typen protrombine bij vitamine-K-deficiëntie

Hemker, H. C., Muller, A. D. & Loeliger, E. A., 26 Dec 1970, In : Nederlands Tijdschrift voor Geneeskunde. 114, 52, p. 2197-2198 2 p.

Research output: Contribution to journalArticleAcademic

Open Access
File

Two types of prothrombin in vitamin K deficiency

Hemker, H. C., Muller, A. D. & Loeliger, E. A., 30 Jun 1970, In : Thrombosis et diathesis haemorrhagica. 23, 3, p. 633-637 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

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1971

Additional evidence for the existence of a precursor molecule of the prothrombin complex in oral anticoagulation

Veltkamp, J. J., Muis, H., Muller, A. D., Hemker, H. C. & Loeliger, E. A., 30 Jun 1971, In : Thrombosis et diathesis haemorrhagica. 25, 2, p. 312-315 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

File

De plaats van de kliniek in de biochemie

Hemker, H. C. & Kassenaar, A. A. H., 1 Jan 1971, In : Universiteit en hogeschool. 18, 4, p. 314-322 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetics of coagulation and immunological processes

Hemker, H. C., 1971, Immunological Mechanisms in Blood Coagulation, Thrombosis and Hemostasis: New Developments in Antithrombotic Therapy: Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis and the International Society on Thrombosis and Haemostasis Montreux, Switzerland, July 28 to August 7, 1970. Duckert, F., Brinkhous, K. M., Hinnom, S., Koller, F., Sherry, S. & Stengle, J. M. (eds.). 1 ed. Stuttgart: F. K. Schattauer Verlag, p. 119-124 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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2 Downloads (Pure)

Praktische aspecten van de antistollingsbehandeling

Hemker, H. C. & Veltkamp, J. J., 1 Jan 1971, In : Hart Bulletin. 2, p. 60-66 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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The evaluation of the two-stage prothrombin assay

Hemker, H. C., Hemker, P. W., v.d. Torren, K., Devilee, P. P., Hermens, W. T. & Loeliger, E. A., 1 Jan 1971, In : Thrombosis et diathesis haemorrhagica. 25, 3, p. 545-554 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Theoretical considerations on a thermodynamic mode of muscle action

Hemker, H. C. & Hermens, W. TH., 1971, In : Cardiovascular Research. 5, Suppl. 1, p. 84-86 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

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1972

Artificial reagents for factor VII and factor X: A computer programme for obtaining reference tables for one-stage determinations in the extrinsic system

Hemker, H. C., Swart, A. C. W. & Alink, A. J. M., 30 Apr 1972, In : Thrombosis et diathesis haemorrhagica. 27, 2, p. 205-211 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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De lotgevallen van protrombine bij vitamine-K-deficiëntie

Hemker, H. C., 1972, In : Nederlands Tijdschrift voor Geneeskunde. 116, 42, p. 1877-1880 4 p.

Research output: Contribution to journalArticleAcademic

Open Access

Estimation of the rate constants in the Michaelis-Menten equations without restrictions as to time scale

Willems, G. M. & Hemker, H. C., 1972, In : Febs Letters. 24, 3, p. 293-295 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Inhibition of blood coagulation factors by serine esterase inhibitors

de Lange, J. A. & Hemker, H. C., 1972, In : Febs Letters. 24, 3, p. 265-268 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Lack of PIVKA effect in the abnormal factor X (factor X friuli) coagulation disorder

Girolami, A., Muller, A. D. & Hemker, H. C., 1972, In : Haemostasis. 1, 1, p. 23-30 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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On the theory of the generation of stable inhomogeneous states in homogeneous mixtures

Hermens, W. T., Hemker, P. W. & Hemker, H. C., 1 Jan 1972, Analysis and Simulation of Biochemical Systems. Hemker, H. C. & Hess, B. (eds.). 1 ed. Amsterdam: North-Holland Publ Co, p. 19-37 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

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1 Downloads (Pure)

Purification of blood coagulation factors II, VII, IX and X from bovine citrated plasma

Reekers, P. & Hemker, H. C., 1972, In : Haemostasis. 1, 1, p. 2-22 21 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
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