• P. Debyelaan 25

    6229 HX Maastricht

    Netherlands

Research Output

2020

Blood Pressure Variability: causes and consequences

Zhou, T. L., 2020

Research output: ThesisDoctoral ThesisInternal

Oxygen Sensors in Atherosclerosis

Demandt, J. A. F., 2020, Ridderprint. 302 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
123 Downloads (Pure)

Approximation of a pipeline of unsupervised retina image analysis methods with a CNN

Heslinga, F. G., Pluim, J. P. W., Dashtbozorg, B., Berendschot, T., Houben, B., Henry, R. & Veta, M., 2019, Image Processing. Vol. 10949. 109491N

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

Mandaviya, P. R., Joehanes, R., Brody, J., Castillo-Fernandez, J. E., Dekkers, K. F., Do, A. N., Graff, M., Hänninen, I. K., Tanaka, T., de Jonge, E. A. L., Kiefte-de Jong, J. C., Absher, D. M., Aslibekyan, S., de Rijke, Y. B., Fornage, M., Hernandez, D. G., Hurme, M. A., Ikram, M. A., Jacques, P. F., Justice, A. E. & 28 others, Kiel, D. P., Lemaitre, R. N., Mendelson, M. M., Mikkilä, V., Moore, A. Z., Pallister, T., Raitakari, O. T., Schalkwijk, C. G., Sha, J., Slagboom, E. P. E., Smith, C. E., Stehouwer, C. D. A., Tsai, P-C., Uitterlinden, A. G., van der Kallen, C. J. H., van Heemst, D., Arnett, D. K., Bandinelli, S., Bell, J. T., Heijmans, B. T., Lehtimäki, T., Levy, D., North, K. E., Sotoodehnia, N., van Greevenbroek, M. M. J., van Meurs, J. B. J., Heil, S. G. & BIOS Consortium, CHARGE Consortium Epigenetics Working Group, CHARGE Consortium Nutrition Working Group, Aug 2019, In : American Journal of Clinical Nutrition. 110, 2, p. 437-450 14 p., 15.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Body composition is a strong predictor of local carotid stiffness in Swedish, young adults - the cross sectional Lifestyle, biomarkers, and atherosclerosis study

Fernberg, U., Roodt, J. O., Fernstrom, M. & Hurtig-Wennlof, A., 27 Aug 2019, In : BMC Cardiovascular disorders. 19, 1, 10 p., 205.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Consumption of dairy products in relation to the presence of clinical knee osteoarthritis: The Maastricht Study

Denissen, K. F. M., Boonen, A., Nielen, J. T. H., Feitsma, A. L., van den Heuvel, E. G. H. M., Emans, P. J., Stehouwer, C. D. A., Sep, S. J. S., van Dongen, M. C. J. M., Dagnelie, P. C. & Eussen, S. J. P. M., Oct 2019, In : European Journal of Nutrition. 58, 7, p. 2693-2704 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Depression in the elderly: focus on high risk groups

Janssen, E., 2019

Research output: ThesisDoctoral ThesisExternal prepared

Dynamic sitting: Measurement and associations with metabolic health

van der Berg, J. D., Stehouwer, C. D. A., Bosma, H., Caserotti, P., Eiriksdottir, G., Arnardottir, N. Y., Van Domelen, D. R., Brychta, R. J., Chen, K. Y., Sveinsson, T., Johannsson, E., Launer, L. J., Gudnason, V., Jonsson, P. V., Harris, T. B. & Koster, A., 3 Aug 2019, In : Journal of Sports Sciences. 37, 15, p. 1746-1754 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D. L., Moffitt, T. E., Poulton, R., Franke, B., Boomsma, D., Heijmans, B. T., t'Hoen, P. A. G., van Meurs, J., Isaacs, A., Jansen, R., Franke, L., Pool, R. & 31 others, Hottenga, J. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Slagboom, P. E., Beekman, M., Deelen, J., van Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., van Rooij, J., Lakenberg, N., Mei, H., van Iterson, M., van Galen, M., Bot, J., Zhernakova, D., van t'Hof, P. & BIOS Consortium, 15 Oct 2019, In : Biological Psychiatry. 86, 8, p. 599-607 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
101 Downloads (Pure)

Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children

Zhong, H., Penders, J., Shi, Z., Ren, H., Cai, K., Fang, C., Ding, Q., Thijs, C., Blaak, E. E., Stehouwer, C. D. A., Xu, X., Yang, H., Wang, J., Wang, J., Jonkers, D. M. A. E., Masclee, A. A. M., Brix, S., Li, J., Arts, I. C. W. & Kristiansen, K., 4 Jan 2019, In : Microbiome. 7, 14 p., 2.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study

Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A. & Brouwers, M. C. G. J., Jan 2019, In : Atherosclerosis. 280, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

Onderwater, G. L. J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., van der Kallen, C. J. H., Vijfhuizen, L. S., Pool, R., Liu, J., Vanmolkot, F. H. M., Beekman, M., Wen, K., Amin, N., Thesing, C. S., Pijpers, J. A., Kies, D. A., Zielman, R., de Boer, I., van Greevenbroek, M. M. J., Arts, I. C. W. & 17 others, Milaneschi, Y., Schram, M. T., Dagnelie, P. C., Franke, L., Ikram, M. A., Ferrari, M. D., Goeman, J. J., Slagboom, P. E., Wijmenga, C., Stehouwer, C. D. A., Boomsma, D. I., van Duijn, C. M., Penninx, B. W., 't Hoen, P. A. C., Terwindt, G. M., van den Maagdenberg, A. M. J. M. & BBMRI Metabolomics Consortium, 16 Apr 2019, In : Neurology. 92, 16, p. E1899-E1911 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Macrovasculature and Microvasculature at the Crossroads Between Type 2 Diabetes Mellitus and Hypertension

Climie, R. E., van Sloten, T. T., Bruno, R-M., Taddei, S., Empana, J-P., Stehouwer, C. D. A., Sharman, J. E., Boutouyrie, P. & Laurent, S., Jun 2019, In : Hypertension. 73, 6, p. 1138-1149 12 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Porcu, E., Rueger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Fave, M-J., Franke, L., Frayling, T. & 32 others, Gharib, S. A., Gibson, G., Heijmans, B. T., Hemani, G., Jansen, R., Kahonen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Kovacs, P., Krohn, K., Kronberg-Guzman, J., Kukushkina, V., Lee, B., Lehtimaki, T., Loeffler, M., Marigorta, U. M., Mei, H., Milani, L., Montgomery, G. W., Mueler-Nurasyid, M., Nauck, M., Stehouwer, C. D. A., Isaacs, A., Schalkwijk, C. G., Stehouwer, C. D. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., eQTLGen Consortium & BIOS Consortium, 24 Jul 2019, In : Nature Communications. 10, 12 p., 3300.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
124 Downloads (Pure)

Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content

Simons, N., Debray, F-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D. & Brouwers, M. C. G. J., Nov 2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 11, p. 5053-5061 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Plasma metabolomics identifies markers of kidney function in 3,064 Europeans with type 2 diabetes

Ahluwalia, T. S., Tofte, N., Vogelzangs, N., Mook-Kanamori, D., Brahimaj, A., Frimodt-Moller, M., Arts, I., Beulens, J., van der Heijden, A., Stehouwer, C., Nijpels, G., van Greevenbroek, M., van der Kallen, C., Rossing, P. & 't Hart, L. M., Sep 2019, In : Diabetologia. 62, p. S456-S456 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Psychiatric disorders as risk factors for the development of type 2 diabetes mellitus: an umbrella review protocol

Lindekilde, N., Nefs, G., Henriksen, J. E., Lasgaard, M., Schram, M., Rubin, K., Rutters, F., Kivimaki, M. & Pouwer, F., May 2019, In : BMJ Open. 9, 5, 5 p., 024981.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Open Access

Sex differences in cardiovascular risk management for people with diabetes in primary care: a cross-sectional study

de Jong, M., Vos, R. C., de Ritter, R., van der Kallen, C. J., Sep, S. J., Woodward, M., Stehouwer, C. DA., Bots, M. L. & Peters, S. A., Jul 2019, In : BJGP Open. 3, 2, p. 1-11 bjgpopen19X101645.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Skewed X-inactivation is common in the general female population

Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H. H. M., White, S. J., Santen, G. W. E., Lopes, S. M. C. D. S., Heijmans, B. T., van Meurs, J., Jansen, R., Franke, L., Kielbasa, S. M., den Dunnen, J. T., 't Hoen, P. A. C., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., Van Greevenbroek, M. M. J. & 32 others, Da Stehouwer, C., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Slagboom, P. E., Beekman, M., Deelen, J., van Heemst, D., Veldink, J. H., van den Berg, L. H., van Duijn, C. M., Hofman, B. A., Uitterlinden, A. G., Jhamai, P. M., Verbiest, M., Suchiman, H. E. D., Verkerk, M., van der Breggen, R., Isaacs, A., van Dijk, F., Li, M., Isaacs, A., Cox, D. R., Li, Y., Chen, R., Li, N., Wang, J., van Ommen, G. J., BIOS Consortium & GoNL Consortium, Mar 2019, In : European Journal of Human Genetics. 27, 3, p. 455-465 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans

van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., Astrup, A., Valsesia, A., Langin, D., van der Kallen, C. J. H., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., Goossens, G. H., Arts, I. C. W., Jocken, J. W. E., Evelo, C. T. & Blaak, E. E., Dec 2019, In : Diabetes. 68, 12, p. 2247-2258 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

The Association Between β-Blocker Use and Cardiorespiratory Fitness: The Maastricht Study

Nielen, J. T. H., de Vries, F., van der Velde, J. H. P. M., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Schram, M., Stehouwer, C. D. A., Boonen, A., Koster, A. & van den Bemt, B. J. F., 1 Jan 2019, In : Journal of Cardiovascular Pharmacology and Therapeutics. 24, 1, p. 37-45 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The complement system and obesity-associated metabolic disorders: The CODAM study

Xin, Y., 2019, Maastricht: Gildeprint Drukkerijen. 217 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
117 Downloads (Pure)

The Maastricht FFQ: Development and validation of a comprehensive food frequency questionnaire for the Maastricht study

van Dongen, M. C. J. M., Wijckmans-Duysens, N. E. G., den Biggelaar, L. J. C. J., Ocke, M. C., Meijboom, S., Brants, H. A. M., de Vries, J. H. M., Feskens, E. J. M., Bueno-de-Mesquita, H. B., Geelen, A., Stehouwer, C. D. A., Dagnelie, P. C. & Eussen, S. J. P. M., Jun 2019, In : Nutrition. 62, p. 39-46 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Trends in mortality, cardiovascular complications, and risk factors in type 2 diabetes

Heintjes, E. M., Houben, E., Beekman-Hendriks, W. L., Lighaam, E., Cremers, S. M., Penning-van Beest, F. J. A., Stehouwer, C. D. A. & Herings, R. M. C., Nov 2019, In : Netherlands Journal of Medicine. 77, 9, p. 317-329 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Use of proton pump inhibitors and risk of iron deficiency: a population-based case-control study

Tran-Duy, A., Connell, N. J., Vanmolkot, F. H., Souverein, P. C., de Wit, N. J., Stehouwer, C. D. A., Hoes, A. W., de Vries, F. & de Boer, A., Feb 2019, In : Journal of Internal Medicine. 285, 2, p. 205-214 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Abdominal subcutaneous adipose tissue gene expression in relation to tissue-specific insulin resistance in human obesity

CODAM study, Maastricht Study & DiOGenes Consortium, Oct 2018, In : Diabetologia. 61, p. S110-S110 1 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans

Verboven, K., Wouters, K., Gaens, K., Hansen, D., Bijnen, M., Wetzels, S., Stehouwer, C. D., Goossens, G. H., Schalkwijk, C. G., Blaak, E. E. & Jocken, J. W., 16 Mar 2018, In : Scientific Reports. 8, 8 p., 4677.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice

Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G. & Wouters, K., Jul 2018, In : Gut. 67, 7, p. 1317-1327 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

A gene variant near ATM affects the response to metformin and metformin plasma levels: a post hoc analysis of an RCT

Out, M., Becker, M. L., van Schaik, R. H., Lehert, P., Stehouwer, C. D. & Kooy, A., 1 Jun 2018, In : Pharmacogenomics. 19, 8, p. 715-726 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

274 Downloads (Pure)