Carim - Cell biochemistry of thrombosis and haemostasis

Research output

Research output per year 2019 2021 2022 2023 2024

• 117 Article
• 18 (Systematic) Review article
• 16 Doctoral Thesis
• 6 Editorial
• 6 More
  • 3 Comment/Letter to the editor
  • 1 Conference Abstract/Poster in journal
  • 1 Book/Film/Article review
  • 1 Erratum / corrigendum / retractions

Research output per year

Research output per year

Search results

• Age- and gender-matched controls needed for platelet-based biomarker studies

  Sabrkhany, S., Kuijpers, M. J. E., Van Kuijk, S. M. J., Griffioen, A. W. & Oude Egbrink, M. G. A., 1 Jun 2023, In: Haematologica-the Hematology Journal. 108, 6, p. 1667-1670 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  24 Downloads (Pure)

• Altered whole blood thrombin generation and hyperresponsive platelets in patients with pancreatic cancer

  Willems, R. A. L., Konings, J., Huskens, D., Middelveld, H., Pepels-Aarts, N., Verbeet, L., de Groot, P. G., Heemskerk, J. W. M., Ten Cate, H., de Vos-Geelen, J., de Laat, B. & Roest, M., Apr 2024, In: Journal of Thrombosis and Haemostasis. 22, 4, p. 1132-1144 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts

  Tantiwong, C., Dunster, J. L., Cavill, R., Tomlinson, M. G., Wierling, C., Heemskerk, J. W. M. & Gibbins, J. M., 8 Mar 2023, In: Scientific Reports. 13, 1, 15 p., 3906.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Antagonistic Roles of Human Platelet Integrin aIIbβ3 and Chemokines in Regulating Neutrophil Activation and Fate on Arterial Thrombi Under Flow

  Schönichen, C., Montague, S. J., Brouns, S. L. N., Burston, J. J., Cosemans, J. M. E. M., Jurk, K., Kehrel, B. E., Koenen, R. R., Ní Áinle, F., O'Donnell, V. B., Soehnlein, O., Watson, S. P., Kuijpers, M. J. E., Heemskerk, J. W. M. & Nagy, M., Sept 2023, In: Arteriosclerosis Thrombosis and Vascular Biology. 43, 9, p. 1700-1712 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Antibody-mediated depletion of human CLEC-2 in a novel humanized mouse model

  Brown, H. C., Beck, S., Navarro, S., Di, Y., Soriano Jerez, E. M., Kaczmarzyk, J., Thomas, S. G., Mirakaj, V., Watson, S. P., Nieswandt, B. & Stegner, D., 28 Mar 2023, In: Blood advances. 7, 6, p. 997-1000 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation

  Jooss, N. J., Smith, C. W., Slater, A., Montague, S. J., Di, Y., O'Shea, C., Thomas, M. R., Henskens, Y. M. C., Heemskerk, J. W. M., Watson, S. P. & Poulter, N. S., Nov 2022, In: Journal of Thrombosis and Haemostasis. 20, 11, p. 2617-2631 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions

  Huang, J., Swieringa, F., Solari, F. A., Provenzale, I., Grassi, L., De Simone, I., Baaten, C. C. F. M. J., Cavill, R., Sickmann, A., Frontini, M. & Heemskerk, J. W. M., 11 Jun 2021, In: Scientific Reports. 11, 1, 18 p., 12358.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Atherosclerotic plaque injury-mediated murine thrombosis models: advantages and limitations

  Karel, M. F. A., Hechler, B., Kuijpers, M. J. E. & Cosemans, J. M. E. M., 19 Jan 2020, In: Platelets. 31, 4, p. 439-446 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study

  Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B. & Hazebroek, M. R., 1 Sept 2023, In: Journal of Clinical Medicine. 12, 17, 12 p., 5695.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy

  Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Venner, M. F. G. H. M., Li, X., Heymans, S. R. B., Hazebroek, M. R. & Verdonschot, J. A. J., 1 Jun 2023, In: Journal of Clinical Medicine. 12, 12, 11 p., 3937.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

  Lacy, M., Buerger, C., Shami, A., Ahmadsei, M., Winkels, H., Nitz, K., van Tiel, C. M., Seijkens, T. T. P., Kusters, P. J. H., Karshovka, E., Prange, K. H. M., Wu, Y., Brouns, S. L. N., Unterlugauer, S., Kuijpers, M. J. E., Reiche, M. E., Steffens, S., Edsfeldt, A., Megens, R. T. A., Heemskerk, J. W. M., & 5 othersGoncalves, I., Weber, C., Gerdes, N., Atzler, D. & Lutgens, E., 18 Jun 2021, In: Nature Communications. 12, 1, 12 p., 3754.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays

  Karel, M. F. A., Lemmens, T. P., Tullemans, B. M. E., Wielders, S. J. H., Gubbins, E., van Beurden, D., van Rijt, S. & Cosemans, J. M. E. M., Feb 2022, In: Cellular and Molecular Bioengineering. 15, 1, p. 55-65 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Characterization of cerebral small vessel disease by neutrophil and platelet activation markers using artificial intelligence

  Karel, M. F. A., Roosen, M. G. C. H., Tullemans, B. M. E., Zhang, C. E., Staals, J., Cosemans, J. M. E. M. & Koenen, R. R., 15 Jun 2022, In: Journal of Neuroimmunology. 367, 10 p., 577863.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization

  Damaskinaki, F-N., Jooss, N. J., Martin, E. M., Clark, J. C., Thomas, M. R., Poulter, N. S., Emsley, J., Kellam, B., Watson, S. P. & Slater, A., Feb 2023, In: Journal of Thrombosis and Haemostasis. 21, 2, p. 317-328 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• CLEC-2 Supports Platelet Aggregation in Mouse but not Human Blood at Arterial Shear

  Bourne, J. H., Smith, C. W., Jooss, N. J., Di, Y., Brown, H. C., Montague, S. J., Thomas, M. R., Poulter, N. S., Rayes, J. & Watson, S. P., Dec 2022, In: Thrombosis and Haemostasis. 122, 12, p. 1988-2000 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Clinical Protocol to Prevent Thrombogenic Effect of Liver-Derived Mesenchymal Cells for Cell-Based Therapies

  Coppin, L., Najimi, M., Bodart, J., Rouchon, M-S., van der Smissen, P., Eeckhoudt, S., Dahlqvist, G., Castanares-Zapatero, D., Komuta, M., Brouns, S. L., Baaten, C. C., Heemskerk, J. W. M., Horman, S., Belmonte, N., Sokal, E. & Stephenne, X., Aug 2019, In: Cells. 8, 8, 16 p., 846.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Clonal Hematopoiesis has Prognostic Value in Dilated Cardiomyopathy independent of Age and Clone Size

  Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Cossins, B., van Deuren, R. C., Steehouwer, M., Riksen, N. P., van den Wijngaard, A., Brunner, H. G., Hoischen, A., Verdonschot, J. A. J. & Heymans, S. R. B., 25 Aug 2023, (E-pub ahead of print) In: JACC: Heart Failure. 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Clustering of Cardiac Transcriptome Profiles Reveals Unique Subgroups of Dilated Cardiomyopathy Patients

  Verdonschot, J. A. J., Wang, P., Derks, K. W. J., Adriaens, M. E., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Sikking, M., de Koning, B., van den Wijngaard, A., Krapels, I. P. C., Nabben, M., Brunner, H. G. & Heymans, S. R. B., 1 Apr 2023, In: JACC: Basic to Translational Science. 8, 4, p. 406-418 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• CMR-derived left ventricular intraventricular pressure gradients identify different patterns associated with prognosis in dilated cardiomyopathy

  Vos, J. L., Raafs, A. G., Henkens, M. T. H. M., Pedrizzetti, G., van Deursen, C. J., Rodwell, L., Heymans, S. R. B. & Nijveldt, R., 23 Aug 2023, In: European Heart Journal Cardiovascular Imaging. 24, 9, p. 1231-1240 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Coagulation Factor XIIIa and Activated Protein C Activate Platelets via GPVI and PAR1

  De Simone, I., Baaten, C. C. F. M. J., Jandrot-Perrus, M., Gibbins, J. M., Ten Cate, H., Heemskerk, J. W. M., Jones, C. I. & van der Meijden, P. E. J., 6 Sept 2022, In: International journal of molecular sciences. 23, 18, 14 p., 10203.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Combined Antiplatelet Therapy Reduces the Proinflammatory Properties of Activated Platelets

  Heinzmann, A. C. A., Coenen, D. M., Vajen, T., Cosemans, J. M. E. M. & Koenen, R. R., Oct 2021, In: TH open : companion journal to thrombosis and haemostasis. 5, 4, p. e533-e542

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis

  Nagy, M., van Geffen, J. P., Stegner, D., Adams, D. J., Braun, A., de Witt, S. M., Elvers, M., Geer, M. J., Kuijpers, M. J. E., Kunzelmann, K., Mori, J., Oury, C., Pircher, J., Pleines, I., Poole, A. W., Senis, Y. A., Verdoold, R., Weber, C., Nieswandt, B., Heemskerk, J. W. M., & 1 othersBaaten, C. C. F. M. J., 30 Jul 2019, In: Frontiers in Cardiovascular Medicine. 6, 15 p., 99.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function

  Tullemans, B., Karel, M., Léopold, V., ten Brink, M. S., Baaten, C., Maas, S. L., de Vos, A. F., Eble, J. A., Nijziel, M. R., van der Vorst, E., Cosemans, J., Heemskerk, J., Claushuis, T. A. M. & Kuijpers, M., 2021, In: eJHaem. 2, 4, p. 685–699

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Comparison of the GPVI inhibitors losartan and honokiol

  Onselaer, M-B., Nagy, M., Pallini, C., Pike, J. A., Perrella, G., Quintanilla, L. G., Eble, J. A., Poulter, N. S., Heemskerk, J. W. M. & Watson, S. P., 17 Feb 2020, In: Platelets. 31, 2, p. 187-197 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Complementary roles of platelet αIIbβ3 integrin, phosphatidylserine exposure and cytoskeletal rearrangement in the release of extracellular vesicles

  Heinzmann, A. C. A., Karel, M. F. A., Coenen, D. M., Vajen, T., Meulendijks, N. M. M., Nagy, M., Suylen, D. P. L., Cosemans, J. M. E. M., Heemskerk, J. W. M., Hackeng, T. M. & Koenen, R. R., Oct 2020, In: Atherosclerosis. 310, p. 17-25 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Crucial roles of red blood cells and platelets in whole blood thrombin generation

  Sun, S., Campello, E., Zou, J., Konings, J., Huskens, D., Wan, J., Fernández, D. I., Reutelingsperger, C., Ten Cate, H., Toffanin, S., Bulato, C., de Groot, P. G., de Laat, B., Simioni, P., Heemskerk, J. W. M. & Roest, M., 14 Nov 2023, In: Blood advances. 7, 21, p. 6717-6731 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism

  Shi, C., Kim, T., Steiger, S., Mulay, S. R., Klinkhammer, B. M., Baeuerle, T., Melica, M. E., Romagnani, P., Moeckel, D., Baues, M., Yang, L., Brouns, S. L. N., Heemskerk, J. W. M., Braun, A., Lammers, T., Boor, P. & Anders, H-J., 10 Apr 2020, In: Circulation Research. 126, 8, p. E37-E52 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Defective Zn2+ homeostasis in mouse and human platelets with α- and δ-storage pool diseases

  Gotru, S. K., van Geffen, J. P., Nagy, M., Mammadova-Bach, E., Eilenberger, J., Volz, J., Manukjan, G., Schulze, H., Wagner, L., Eber, S., Schambeck, C., Deppermann, C., Brouns, S., Nurden, P., Greinacher, A., Sachs, U., Nieswandt, B., Hermanns, H. M., Heemskerk, J. W. M. & Braun, A., 6 Jun 2019, In: Scientific Reports. 9, 7 p., 8333.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve

  Melo, S. F., Nondonfaz, A., Aqil, A., Pierrard, A., Hulin, A., Delierneux, C., Ditkowski, B., Gustin, M., Legrand, M., Tullemans, B. M. E., Brouns, S. L. N., Nchimi, A., Carrus, R., Dejosé, A., Heemskerk, J. W. M., Kuijpers, M. J. E., Ritter, J., Steinseifer, U., Clauser, J. C., Jérôme, C., & 2 othersLancellotti, P. & Oury, C., 1 Jan 2024, (E-pub ahead of print) In: Biomaterials Science.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Detection and localization of early- and late-stage cancers using platelet RNA

  In 't Veld, S. G. J. G., Arkani, M., Post, E., Antunes-Ferreira, M., D'Ambrosi, S., Vessies, D. C. L., Vermunt, L., Vancura, A., Muller, M., Niemeijer, A-L. N., Tannous, J., Meijer, L. L., Le Large, T. Y. S., Mantini, G., Wondergem, N. E., Heinhuis, K. M., van Wilpe, S., Smits, A. J., Drees, E. E. E., Roos, E., & 96 othersLeurs, C. E., Tjon Kon Fat, L-A., van der Lelij, E. J., Dwarshuis, G., Kamphuis, M. J., Visser, L. E., Harting, R., Gregory, A., Schweiger, M. W., Wedekind, L. E., Ramaker, J., Zwaan, K., Verschueren, H., Bahce, I., de Langen, A. J., Smit, E. F., van den Heuvel, M. M., Hartemink, K. J., Kuijpers, M. J. E., Oude Egbrink, M. G. A., Griffioen, A. W., Rossel, R., Hiltermann, T. J. N., Lee-Lewandrowski, E., Lewandrowski, K. B., De Witt Hamer, P. C., Kouwenhoven, M., Reijneveld, J. C., Leenders, W. P. J., Hoeben, A., Verdonck-de Leeuw, I. M., Leemans, C. R., Baatenburg de Jong, R. J., Terhaard, C. H. J., Takes, R. P., Langendijk, J. A., de Jager, S. C., Kraaijeveld, A. O., Pasterkamp, G., Smits, M., Schalken, J. A., Łapińska-Szumczyk, S., Łojkowska, A., Żaczek, A. J., Lokhorst, H., van de Donk, N. W. C. J., Nijhof, I., Prins, H-J., Zijlstra, J. M., Idema, S., Baayen, J. C., Teunissen, C. E., Killestein, J., Besselink, M. G., Brammen, L., Bachleitner-Hofmann, T., Mateen, F., Plukker, J. T. M., Heger, M., de Mast, Q., Lisman, T., Pegtel, D. M., Bogaard, H-J., Jassem, J., Supernat, A., Mehra, N., Gerritsen, W., de Kroon, C. D., Lok, C. A. R., Piek, J. M. J., Steeghs, N., van Houdt, W. J., Brakenhoff, R. H., Sonke, G. S., Verheul, H. M., Giovannetti, E., Kazemier, G., Sabrkhany, S., Schuuring, E., Sistermans, E. A., Wolthuis, R., Meijers-Heijboer, H., Dorsman, J., Oudejans, C., Ylstra, B., Westerman, B. A., van den Broek, D., Koppers-Lalic, D., Wesseling, P., Nilsson, R. J. A., Vandertop, W. P., Noske, D. P., Tannous, B. A., Sol, N., Best, M. G. & Wurdinger, T., 12 Sept 2022, In: Cancer Cell. 40, 9, p. 999-1009.e6 17 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Diagnostic and prognostic relevance of using large gene panels in the genetic testing of patients with dilated cardiomyopathy

  Stroeks, S. L. V. M., Hellebrekers, D., Claes, G. R. F., Krapels, I. P. C., Henkens, M. H. T. M., Sikking, M., Vanhoutte, E. K., van den Enden, A., Brunner, H. G., van den Wijngaard, A. & Verdonschot, J. A. J., Jul 2023, In: European Journal of Human Genetics. 31, 7, p. 776-783 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets

  Zhang, P., Solari, F. A., Heemskerk, J. W. M., Kuijpers, M. J. E., Sickmann, A., Walter, U. & Jurk, K., 24 Apr 2023, In: International Journal of Molecular Sciences. 24, 9, 18 p., 7776.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?

  Slater, A., Perrella, G., Onselaer, M-B., Martin, E. M., Gauer, J. S., Xu, R-G., Heemskerk, J. W. M., Ariens, R. A. S. & Watson, S. P., 3 Apr 2019, In: Platelets. 30, 3, p. 281-289 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

• Effect of blood loss during caesarean section on coagulation parameters

  Wasserloos, A., Thomassen, M. C. L. G. D., Costa, S. D., Zenclussen, A., Tchaikovski, V. E., Hackeng, T. M., Stickeler, E. & Tchaikovski, S. N., Jun 2021, In: Thrombosis Research. 202, p. 84-89 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  98 Downloads (Pure)

• Effects of Cancer Presence and Therapy on the Platelet Proteome

  Walraven, M., Sabrkhany, S., Knol, J. C., Dekker, H., de Reus, I., Piersma, S. R., Pham, T., Griffioen, A. W., Broxterman, H. J., Egbrink, M. O., Verheul, H. M. W. & Jimenez, C. R., Aug 2021, In: International journal of molecular sciences. 22, 15, 16 p., 8236.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Effects of Platelet Agonists and Priming on the Formation of Platelet Populations

  Veninga, A., Baaten, C. C. F. M. J., De Simone, I., Tullemans, B. M. E., Kuijpers, M. J. E., Heemskerk, J. W. M. & van der Meijden, P. E. J., May 2022, In: Thrombosis and Haemostasis. 122, 05, p. 726-738 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Endothelium-mediated regulation of platelet activation: Involvement of multiple protein kinases

  Provenzale, I., Solari, F. A., Schoenichen, C., Brouns, S. L. N., Fernandez, D. I., Kuijpers, M. J. E., van Der Meijden, P. E. J., Gibbins, J. M., Sickmann, A., Jones, C. & Heemskerk, J. W. M., 29 Feb 2024, In: Faseb Journal. 38, 4, 21 p., e23468.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins

  Maqsood, Z., Clark, J. C., Martin, E. M., Cheung, Y. F. H., Morán, L. A., Watson, S. E. T., Pike, J. A., Di, Y., Poulter, N. S., Slater, A., Lange, B. M. H., Nieswandt, B., Eble, J. A., Tomlinson, M. G., Owen, D. M., Stegner, D., Bridge, L. J., Wierling, C. & Watson, S. P., Nov 2022, In: PLoS Computational Biology. 18, 11, 28 p., e1010708.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Finding the "switch" in platelet activation: prediction of key mediators involved in reversal of platelet activation using a novel network biology approach

  Lemmens, T. P., Coenen, D. M., Swieringa, F., Niessen, I. C. L., Coort, S. L. M., Koenen, R. R., Kutmon, M. & Cosemans, J. M. E. M., Jun 2022, In: Journal of Proteomics. 261, 11 p., 104577.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions

  Nagy, M., Perrella, G., Dalby, A., Becerra, M. F., Quintanilla, L. G., Pike, J. A., Morgan, N., Gardiner, E. E., Heemskerk, J. W. M., Azocar, L., Miquel, J. F., Mezzano, D. & Watson, S. P., 14 Jul 2020, In: Blood advances. 4, 13, p. 2953-2961 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro

  Dickhout, A., Tullemans, B. M. E., Heemskerk, J. W. M., Thijssen, V. L. J. L., Kuijpers, M. J. E. & Koenen, R. R., 7 Jan 2021, In: PLOS ONE. 16, 1, 18 p., e0244736.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Galectin-9 activates platelet ITAM receptors glycoprotein VI and C-type lectin-like receptor-2

  Zhi, Z. G., Jooss, N. J., Sun, Y., Colicchia, M., Slater, A., Moran, L. A., Cheung, H. Y. F., Di, Y., Rayes, J., Poulter, N. S., Watson, S. P. & Iqbal, A. J., Apr 2022, In: Journal of Thrombosis and Haemostasis. 20, 4, p. 936-950 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• GPVI expression is linked to platelet size, age, and reactivity

  Veninga, A., Handtke, S., Aurich, K., Tullemans, B., Brouns, S., Schwarz, S. L., Heubel-Moenen, F. C., Greinacher, A., Heemskerk, J. W. M., van der Meijden, P. & Thiele, T., 26 Jul 2022, In: Blood advances. 6, 14, p. 4162-4173 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• High fibrinogen gamma ' levels in patient plasma increase clot formation a arterial and venous shear

  Macrae, F. L., Swieringa, F., Heemskerk, J. W. M. & Ariens, R. A. S., 14 Sept 2021, In: Blood advances. 5, 17, p. 3468-3477 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• High-throughput assessment identifying major platelet Ca2+ entry pathways via tyrosine kinase-linked and G protein-coupled receptors

  Cheung, H. Y. F., Zou, J., Tantiwong, C., Fernandez, D. I., Huang, J., Ahrends, R., Roest, M., Cavill, R., Gibbins, J. & Heemskerk, J. W. M., Jun 2023, In: Cell Calcium. 112, 15 p., 102738.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

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• High-throughput elucidation of thrombus formation reveals sources of platelet function variability

  van Geffen, A., Brouns, S., Batista, J., McKinney, H., Kempster, C., Nagy, M., Sivapalaratnam, S., Baaten, C., Bourry, N., Frontini, M., Jurk, K., Krause, M., Pilliteri, D., Swieringa, F., Verdoold, R., Cavill, R., Kuijpers, M., Ouwehand, W. H., Downes, K. & Heemskerk, J., 31 May 2019, In: Haematologica-the Hematology Journal. 104, 6, p. 1256-1267 12 p.

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• High-throughput microfluidic blood testing to phenotype genetically linked platelet disorders: an aid to diagnosis

  Fernández, D. I., Provenzale, I., Canault, M., Fels, S., Lenz, A., Andresen, F., Krümpel, A., Dupuis, A., Heemskerk, J. W. M., Boeckelmann, D. & Zieger, B. M. H., 24 Oct 2023, In: Blood advances. 7, 20, p. 6163-6177 15 p.

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• Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis

  Govers-Riemslag, J. W. P., Konings, J., Cosemans, J. M. E. M., van Geffen, J. P., de Laat, B., Heemskerk, J. W. M., Dargaud, Y. & Ten Cate, H., Jul 2019, In: TH open : companion journal to thrombosis and haemostasis. 3, 3, p. e273-e285 13 p.

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• Impaired iloprost-induced platelet inhibition and phosphoproteome changes in patients with confirmed pseudohypoparathyroidism type Ia, linked to genetic mutations in GNAS

  Swieringa, F., Solari, F. A., Pagel, O., Beck, F., Huang, J., Feijge, M. A. H., Jurk, K., Koerver-Keularts, I. M. L. W., Mattheij, N. J. A., Faber, J., Pohlenz, J., Russo, A., Stumpel, C. T. R. M., Schrander, D. E., Zieger, B., van Der Meijden, P. E. J., Zahedi, R. P., Sickmann, A. & Heemskerk, J. W. M., 9 Jul 2020, In: Scientific Reports. 10, 1, 16 p., 11389.

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• Increased platelet thrombus formation under flow conditions in whole blood from polycythaemia vera patients

  Vignoli, A., Gamba, S., van der Meijden, P. E. J., Marchetti, M., Russo, L., Tessarolo, S., Giaccherini, C., Swieringa, F., Cate, H. T., Finazzi, G., Heemskerk, J. W. M. & Falanga, A., 2022, In: Blood Transfusion. 20, 2, p. 143-151 9 p.

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