• Universiteitssingel50, UNS50

    6229 ER Maastricht

    Netherlands

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2019

2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction

Schloss, M. J., Horckmans, M., Guillamat-Prats, R., Hering, D., Lauer, E., Lenglet, S., Weber, C., Thomas, A. & Steffens, S., Mar 2019, In : Cardiovascular Research. 115, 3, p. 602-613 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Acetaminophen Overdose as a Potential Risk Factor for Parkinson's Disease

Bohler, S., Liu, X., Krauskopf, J., Gaiment, F., Aubrecht, J., Nicolaes, G. A. F., Kleinjans, J. C. S. & Briede, J. J., Oct 2019, In : Clinical Pharmacology & Therapeutics. 106, 4, p. 696-696 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Combination of Tamarindus indica seeds and Curcuma longa Rhizome Extracts Improves Knee Joint Function and Alleviates Pain in Non-Arthritic Adults Following Physical Activity

Rao, P. S., Ramanjaneyulu, Y. S., Prisk, V. R. & Schurgers, L. J., 2019, In : International Journal of Medical Sciences. 16, 6, p. 845-853 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage

Schulz, A., Mueller, N. V., van de Lest, N. A., Eisenreich, A., Schmidbauer, M., Barysenka, A., Purfuerst, B., Sporbert, A., Lorenzen, T., Meyer, A. M., Herlan, L., Witten, A., Ruehle, F., Zhou, W., de Heer, E., Scharpfenecker, M., Panakova, D., Stoll, M. & Kreutz, R., 22 Mar 2019, In : Elife. 8, 33 p., 42068.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Analytical characterization and reference interval of an enzyme-linked immunosorbent assay for active von Willebrand factor

van der Vorm, L. N., Li, L., Huskens, D., Chayoua, W., Kelchtermans, H., de Groot, P. G., Roest, M., Remijn, J. A. & de Laat, B., 13 Feb 2019, In : PLOS ONE. 14, 2, 16 p., 0211961.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

Adrover, J. M., del Fresno, C., Crainiciuc, G., Isabel Cuartero, M., Casanova-Acebes, M., Weiss, L. A., Huerga-Encabo, H., Silvestre-Roig, C., Rossaint, J., Cossio, I., Lechuga-Vieco, A. V., Garcia-Prieto, J., Gomez-Parrizas, M., Quintana, J. A., Ballesteros, I., Martin-Salamanca, S., Aroca-Crevillen, A., Chong, S. Z., Evrard, M., Balabanian, K. & 14 others, Lopez, J., Bidzhekov, K., Bachelerie, F., Abad-Santos, F., Munoz-Calleja, C., Zarbock, A., Soehnlein, O., Weber, C., Ng, L. G., Lopez-Rodriguez, C., Sancho, D., Moro, M. A., Ibanez, B. & Hidalgo, A., 19 Feb 2019, In : Immunity. 50, 2, p. 390-402 23 p.

Research output: Contribution to journalArticleAcademicpeer-review

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis

Liu, J., Carnero-Montoro, E., van Dongen, J., Lent, S., Nedeljkovic, I., Ligthart, S., Tsai, P-C., Martin, T. C., Mandaviya, P. R., Jansen, R., Peters, M. J., Duijts, L., Jaddoe, V. W. V., Tiemeier, H., Felix, J. F., Willemsen, G., de Geus, E. J. C., Chu, A. Y., Levy, D., Hwang, S-J. & 37 others, Bressler, J., Gondalia, R., Salfati, E. L., Herder, C., Hidalgo, B. A., Tanaka, T., Moore, A. Z., Lemaitre, R. N., Jhun, M. A., Smith, J. A., Sotoodehnia, N., Bandinelli, S., Ferrucci, L., Arnett, D. K., Grallert, H., Assimes, T. L., Hou, L., Baccarelli, A., Whitsel, E. A., van Dijk, K. W., Amin, N., Uitterlinden, A. G., Sijbrands, E. J. G., Franco, O. H., Dehghan, A., Spector, T. D., Dupuis, J., Hivert, M-F., Rotter, J., Meigs, J. B., Pankow, J. S., van Meurs, J. B. J., Isaacs, A., Boomsma, D., Bell, J. T., Demirkan, A. & van Duijn, C. M., 13 Jun 2019, In : Nature Communications. 10, 11 p., 2581.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

ApoE attenuates unresolvable inflammation by complex formation with activated C1q

Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H-H., Pelisek, J., Herms, J. & 9 others, Roeber, S., Arzberger, T., Borodovsky, A., Habenicht, L., Binder, C. J., Weber, C., Zipfel, P. F., Skerka, C. & Habenicht, A. J. R., Mar 2019, In : Nature Medicine. 25, 3, p. 496-506 23 p.

Research output: Contribution to journalArticleAcademicpeer-review

Assessment and determinants of whole blood and plasma fibrinolysis in patients with mild bleeding symptoms

Vries, M. J. A., Macrae, F., Nelemans, P. J., Kuiper, G. J. A. J. M., Wetzels, R. J. H., Bowman, P., Verhezen, P. W. M., ten Cate, H., Ariens, R. A. S. & Henskens, Y. M. C., Feb 2019, In : Thrombosis Research. 174, p. 88-94 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

A Synthetic Triple Helical Collagen Peptide as a New Agonist for Flow Cytometric Measurement of GPVI-Specific Platelet Activation

Sang, Y., Huskens, D., Wichapong, K., de Laat, B., Nicolaes, G. A. F. & Roest, M., Dec 2019, In : Thrombosis and Haemostasis. 119, 12, p. 2005-2013 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Atypical Chemokine Receptors in Cardiovascular Disease

Gencer, S., van der Vorst, E. P. C., Aslani, M., Weber, C., Doering, Y. & Duchene, J., Apr 2019, In : Thrombosis and Haemostasis. 119, 4, p. 534-541 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Btk Inhibitors as First Oral Atherothrombosis-Selective Antiplatelet Drugs?

Busygina, K., Denzinger, V., Bernlochner, I., Weber, C., Lorenz, R. & Siess, W., Aug 2019, In : Thrombosis and Haemostasis. 119, 8, p. 1212-1221 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cardiovascular risk factors are important determinants of platelet-dependent thrombin generation in adult survivors of childhood cancer

Panova-Noeva, M., Neu, M. A., Eckerle, S., Spix, C., Schneider, A., Schmidtmann, I., Spronk, H. M., Pfeiffer, N., Beutel, M., Lackner, K. J., Muenzel, T., ten Cate, H., Merzenich, H., Faber, J. & Wild, P. S., Apr 2019, In : Clinical research in cardiology. 108, 4, p. 438-447 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis

Pfeiler, S., Thakur, M., Gruenauer, P., Megens, R. T. A., Joshi, U., Coletti, R., Samara, V., Mueller-Stoy, G., Ishikawa-Ankerhold, H., Stark, K., Klingl, A., Froehlich, T., Arnold, G. J., Woermann, S., Bruns, C. J., Alguel, H., Weber, C., Massberg, S. & Engelmann, B., Feb 2019, In : Faseb Journal. 33, 2, p. 1860-1872 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Central Hemodynamics in Relation to Circulating Desphospho-Uncarboxylated Matrix Gla Protein: A Population Study

Wei, F-F., Thijs, L., Cauwenberghs, N., Yang, W-Y., Zhang, Z-Y., Yu, C-G., Kuznetsova, T., Nawrot, T. S., Struijker-Boudier, H. A. J., Verhamme, P., Vermeer, C. & Staessen, J. A., 2 Apr 2019, In : Journal of the American Heart Association. 8, 7, 22 p., 011960.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Cheese and Healthy Diet: Associations With Incident Cardio-Metabolic Diseases and All-Cause Mortality in the General Population

Dekker, L. H., Vinke, P. C., Riphagen, I. J., Minovic, I., Eggersdorfer, M. L., van den Heuvel, E. G. H. M., Schurgers, L. J., Kema, I. P., Bakker, S. J. L. & Navis, G., 17 Dec 2019, In : Frontiers in nutrition. 6, 9 p., 185.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Chemokines as Therapeutic Targets in Cardiovascular Disease The Road Behind, The Road Ahead

Noels, H., Weber, C. & Koenen, R. R., Apr 2019, In : Arteriosclerosis Thrombosis and Vascular Biology. 39, 4, p. 583-592 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Clinical Protocol to Prevent Thrombogenic Effect of Liver-Derived Mesenchymal Cells for Cell-Based Therapies

Coppin, L., Najimi, M., Bodart, J., Rouchon, M-S., van der Smissen, P., Eeckhoudt, S., Dahlqvist, G., Castanares-Zapatero, D., Komuta, M., Brouns, S. L., Baaten, C. C., Heemskerk, J. W. M., Horman, S., Belmonte, N., Sokal, E. & Stephenne, X., Aug 2019, In : Cells. 8, 8, 16 p., 846.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis

Nagy, M., van Geffen, J. P., Stegner, D., Adams, D. J., Braun, A., de Witt, S. M., Elvers, M., Geer, M. J., Kuijpers, M. J. E., Kunzelmann, K., Mori, J., Oury, C., Pircher, J., Pleines, I., Poole, A. W., Senis, Y. A., Verdoold, R., Weber, C., Nieswandt, B., Heemskerk, J. W. M. & 1 others, Baaten, C. C. F. M. J., 30 Jul 2019, In : Frontiers in cardiovascular medicine. 6, 15 p., 99.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions

Derszniak, K., Przyborowski, K., Matyjaszczyk, K., Moorlag, M., de Laat, B., Nowakowska, M. & Chlopicki, S., 20 Feb 2019, In : Frontiers in Pharmacology. 10, 13 p., 68.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Concomitant assessment of rivaroxaban concentration and its impact on thrombin generation

Bloemen, S., Zwaveling, S., Mullier, F. & Douxfils, J., Dec 2019, In : Thrombosis Research. 184, p. 8-15 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Construction of CNA35 Collagen-Targeted Phase-Changeable Nanoagents for Low-Intensity Focused Ultrasound-Triggered Ultrasound Molecular Imaging of Myocardial Fibrosis in Rabbits

Zhou, Q., Zeng, Y., Xiong, Q., Zhong, S., Li, P., Ran, H., Yin, Y., Reutelingsperger, C., Prinze, F. W. & Ling, Z., 3 Jul 2019, In : ACS Applied Materials & Interfaces. 11, 26, p. 23006-23017 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Control of expression and activity of peroxisome proliferated-activated receptor gamma by Annexin A1 on microglia during efferocytosis

Oliveira da Rocha, G. H., Loiola, R. A., Pantaleao, L. D. N., Reutelingsperger, C., Solito, E. & Poliselli Farsky, S. H., Oct 2019, In : Cell Biochemistry and Function. 37, 7, p. 560-568 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases

Gotru, S. K., van Geffen, J. P., Nagy, M., Mammadova-Bach, E., Eilenberger, J., Volz, J., Manukjan, G., Schulze, H., Wagner, L., Eber, S., Schambeck, C., Deppermann, C., Brouns, S., Nurden, P., Greinacher, A., Sachs, U., Nieswandt, B., Hermanns, H. M., Heemskerk, J. W. M. & Braun, A., 6 Jun 2019, In : Scientific Reports. 9, 7 p., 8333.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death

Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slutter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. K., Nicolaes, G. A. F., Daemen, M. J. A. P. & 4 others, Weber, C., Gerdes, N., de Winther, M. P. J. & Lutgens, E., 21 Jan 2019, In : European Heart Journal. 40, 4, p. 372-382 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Detection of Anti-Cardiolipin and Anti-beta 2glycoprotein I Antibodies Differs between Platforms without Influence on Association with Clinical Symptoms

Chayoua, W., Kelchtermans, H., Moore, G. W., Gris, J-C., Musial, J., Wahl, D., Zuily, S., Gianniello, F., Fontana, P., Remijn, J., Urbanus, R. T., de Laat, B. & Devreese, K. M. J., May 2019, In : Thrombosis and Haemostasis. 119, 5, p. 797-806 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders

Downes, K., Megy, K., Duarte, D., Vries, M., Gebhart, J., Hofer, S., Shamardina, O., Deevi, S. V. V., Stephens, J., Mapeta, R., Tuna, S., Al Hasso, N., Besser, M. W., Cooper, N., Daugherty, L., Gleadall, N., Greene, D., Haimel, M., Martin, H., Papadia, S. & 18 others, Revel-Vilk, S., Sivapalaratnam, S., Symington, E., Thomas, W., Thys, C., Tolios, A., Penkett, C. J., Ouwehand, W. H., Abbs, S., Laffan, M. A., Turro, E., Simeoni, I., Mumford, A. D., Henskens, Y. M. C., Pabinger, I., Gomez, K., Freson, K. & NIHR BioResource, 5 Dec 2019, In : Blood. 134, 23, p. 2082-2091 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Does fibrin(ogen) bind to monomeric or dimeric GPVI, or not at all?

Slater, A., Perrella, G., Onselaer, M-B., Martin, E. M., Gauer, J. S., Xu, R-G., Heemskerk, J. W. M., Ariens, R. A. S. & Watson, S. P., 3 Apr 2019, In : Platelets. 30, 3, p. 281-289 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Double bond configuration of palmitoleate is critical for atheroprotection

Cimen, I., Yildirim, Z., Dogan, A. E., Yildirim, A. D., Tufanli, O., Onat, U. I., UyenThao Nguyen, Watkins, S. M., Weber, C. & Erbay, E., Oct 2019, In : Molecular Metabolism. 28, p. 58-72 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults

van Ballegooijen, A. J., Beulens, J. J., Schurgers, L. J., de Koning, E. J., Lips, P., van Schoor, N. M. & Vervloet, M. G., Feb 2019, In : Nutrients. 11, 2, 10 p., 231.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death

Silvestre-Roig, C., Braster, Q., Wichapong, K., Lee, E. Y., Marie Teulon, J., Berrebeh, N., Winter, J., Adrover, J. M., Santos, G. S., Froese, A., Lemnitzer, P., Ortega-Gomez, A., Chevre, R., Marschner, J., Schumski, A., Winter, C., Perez-Olivares, L., Pan, C., Paulin, N., Schoufour, T. & 19 others, Hartwig, H., Gonzalez-Ramos, S., Kamp, F., Megens, R. T. A., Mowen, K. A., Gunzer, M., Maegdefessel, L., Hackeng, T., Lutgens, E., Daemen, M., von Blume, J., Anders, H-J., Nikolaev, V. O., Pellequer, J-L., Weber, C., Hidalgo, A., Nicolaes, G. A. F., Wong, G. C. L. & Soehnlein, O., 9 May 2019, In : Nature. 569, 7755, p. 236-240 25 p.

Research output: Contribution to journalArticleAcademicpeer-review

Extracellular annexin-A1 promotes myeloid/granulocytic differentiation of hematopoietic stem/progenitor cells via the Ca2+/MAPK signalling transduction pathway

Barbosa, C. M., Fock, R. A., Hastreiter, A. A., Reutelingsperger, C., Perretti, M., Paredes-Gamero, E. J. & Farsky, S. H. P., 23 Sep 2019, In : Cell death discovery. 5, 11 p., 135.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Ga-68-DOTA-E[c(RGDfK)](2) PET Imaging of SHARPIN-Regulated Integrin Activity in Mice

Siitonen, R., Peuhu, E., Autio, A., Liljenback, H., Mattila, E., Metsala, O., Kakela, M., Saanijoki, T., Dijkgraaf, I., Jalkanen, S., Ivaska, J. & Roivainen, A., 1 Oct 2019, In : Journal of Nuclear Medicine. 60, 10, p. 1380-1387 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikainen, L-P., Mei, H., Mueller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., Boomsma, D. I. & 41 others, Caulfield, M. J., Eijgelsheim, M., Ford, I., Hansen, T., Harris, T. B., Heckbert, S. R., Hottenga, J-J., Iorio, A., Kors, J. A., Linneberg, A., MacFarlane, P. W., Meitinger, T., Nelson, C. P., Raitakari, O. T., Aldana, C. T. S., Sinagra, G., Sinner, M., Soliman, E. Z., Stoll, M., Uitterlinden, A., van Duijn, C. M., Waldenberger, M., Alonso, A., Gasparini, P., Gudnason, V., Jamshidi, Y., Kaab, S., Kanters, J. K., Lehtimaki, T., Munroe, P. B., Peters, A., Samani, N. J., Sotoodehnia, N., Ulivi, S., Wilson, J. G., de Geus, E. J. C., Jukema, J. W., Stricker, B., van der Harst, P., de Bakker, P. I. W. & Isaacs, A., Jun 2019, In : European Journal of Human Genetics. 27, 6, p. 952-962 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals

Liu, C-T., Merino, J., Rybin, D., DiCorpo, D., Benke, K. S., Bragg-Gresham, J. L., Canouil, M., Corre, T., Grallert, H., Isaacs, A., Kutalik, Z., Lahti, J., Marullo, L., Marzi, C., Rasmussen-Torvik, L. J., Rocheleau, G., Rueedi, R., Scapoli, C., Verweij, N., Vogelzangs, N. & 30 others, Willems, S. M., Yengo, L., Bakker, S. J. L., Beilby, J., Hui, J., Kajantie, E., Müller-Nurasyid, M., Rathmann, W., Balkau, B., Bergmann, S., Eriksson, J. G., Florez, J. C., Froguel, P., Harris, T., Hung, J., James, A. L., Kavousi, M., Miljkovic, I., Musk, A. W., Palmer, L. J., Peters, A., Roussel, R., van der Harst, P., van Duijn, C. M., Vollenweider, P., Barroso, I., Prokopenko, I., Dupuis, J., Meigs, J. B. & Bouatia-Naji, N., 1 Jul 2019, In : Scientific Reports. 9, 1, 8 p., 9439.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report

van der Vorst, E. P. C., Mandl, M., Mueller, M., Neideck, C., Jansen, Y., Hristov, M., Gencer, S., Peters, L. J. F., Meiler, S., Feld, M., Geiselhoeringer, A-L., de Jong, R. J., Ohnmacht, C., Noels, H., Soehnlein, O., Drechsler, M., Weber, C. & Doering, Y., Apr 2019, In : Arteriosclerosis Thrombosis and Vascular Biology. 39, 4, p. 685-693 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation

Cremer, S., Michalik, K. M., Fischer, A., Pfisterer, L., Jae, N., Winter, C., Boon, R. A., Muhly-Reinholz, M., John, D., Uchida, S., Weber, C., Poller, W., Guenther, S., Braun, T., Li, D. Y., Maegdefessel, L., Matic, L. P., Hedin, U., Soehnlein, O., Zeiher, A. & 1 others, Dimmeler, S., 5 Mar 2019, In : Circulation. 139, 10, p. 1320-1334 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Heparins: A Shift of Paradigm

Hemker, H. C., Al Dieri, R. & Beguin, S., 15 Nov 2019, In : Frontiers in medicine. 6, p. 1-8 8 p., 254.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

High-throughput elucidation of thrombus formation reveals sources of platelet function variability

van Geffen, A., Brouns, S., Batista, J., McKinney, H., Kempster, C., Nagy, M., Sivapalaratnam, S., Baaten, C., Bourry, N., Frontini, M., Jurk, K., Krause, M., Pilliteri, D., Swieringa, F., Verdoold, R., Cavill, R., Kuijpers, M., Ouwehand, W. H., Downes, K. & Heemskerk, J., 31 May 2019, In : Haematologia. 104, 6, p. 1256-1267 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hybrid ligands with calixarene and thiodigalactoside groups: galectin binding and cytotoxicity

Zhang, H., Ippel, H., Miller, M. C., Wong, T. J., Griffioen, A. W., Mayo, K. H. & Pieters, R. J., 21 Aug 2019, In : Organic Chemistry Frontiers. 6, 16, p. 2981-2990 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis

Govers-Riemslag, J. W. P., Konings, J., Cosemans, J. M. E. M., van Geffen, J. P., de Laat, B., Heemskerk, J. W. M., Dargaud, Y. & Ten Cate, H., Jul 2019, In : TH open : companion journal to thrombosis and haemostasis. 3, 3, p. e273-e285 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Influence of pH and phosphate concentration on the phosphate binding capacity of five contemporary binders. An in vitro study

Schumacher, S. P., Schurgers, L. J., Vervloet, M. G. & Neradova, A., Feb 2019, In : Nephrology. 24, 2, p. 221-226 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells

Fontaine, M. A. C., Westra, M. M., Bot, I., Jin, H., Franssen, A. J. P. M., Bot, M., de Jager, S. C. A., Dzhagalov, I., He, Y-W., van Vlijmen, B. J. M., Gijbels, M. J. J., Reutelingsperger, C. P., van Berkel, T. J. C., Sluimer, J. C., Temmerman, L. & Biessen, E. A. L., 10 Oct 2019, In : Scientific Reports. 9, 11 p., 14547.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease

Piscaer, I., van den Ouweland, J. M. W., Vermeersch, K., Reynaert, N. L., Franssen, F. M. E., Keene, S., Wouters, E. F. M., Janssens, W., Vermeer, C. & Janssen, R., Aug 2019, In : Journal of Clinical Medicine. 8, 8, 14 p., 1116.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Managing Anti-Platelet Therapy in Thrombocytopaenic Patients with Haematological Malignancy: A Multinational Clinical Vignette-Based Experiment

Leader, A., Ten Cate, V., Ten Cate-Hoek, A. J., Spectre, G., Beckers, E. A. M., Raanani, P., Giaccherini, C., Pereg, D., Schouten, H. C., Falanga, A. & Ten Cate, H., Jan 2019, In : Thrombosis and Haemostasis. 119, 1, p. 163-174 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Porcu, E., Rueger, S., Lepik, K., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., Claringbould, A., Deelen, P., Esko, T., Fave, M-J., Franke, L., Frayling, T. & 32 others, Gharib, S. A., Gibson, G., Heijmans, B. T., Hemani, G., Jansen, R., Kahonen, M., Kalnapenkis, A., Kasela, S., Kettunen, J., Kim, Y., Kirsten, H., Kovacs, P., Krohn, K., Kronberg-Guzman, J., Kukushkina, V., Lee, B., Lehtimaki, T., Loeffler, M., Marigorta, U. M., Mei, H., Milani, L., Montgomery, G. W., Mueler-Nurasyid, M., Nauck, M., Stehouwer, C. D. A., Isaacs, A., Schalkwijk, C. G., Stehouwer, C. D. A., van der Kallen, C. J. H., van Greevenbroek, M. M. J., eQTLGen Consortium & BIOS Consortium, 24 Jul 2019, In : Nature Communications. 10, 12 p., 3300.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

van der Spek, A., Broer, L., Draisma, H. H. M., Pool, R., Albrecht, E., Beekman, M., Mangino, M., Raag, M., Nyholt, D. R., Dharuri, H. K., Codd, V., Amin, N., de Geus, E. J. C., Deelen, J., Demirkan, A., Yet, I., Fischer, K., Haller, T., Henders, A. K., Isaacs, A. & 19 others, Medland, S. E., Montgomery, G. W., Mooijaart, S. P., Strauch, K., Suchiman, H. E. D., Vaarhorst, A. A. M., van Heemst, D., Wang-Sattler, R., Whitfield, J. B., Willemsen, G., Wright, M. J., Martin, N. G., Samani, N. J., Metspalu, A., Slagboom, P. E., Spector, T. D., Boomsma, D., van Duijn, C. M. & Gieger, C., 12 Aug 2019, In : Scientific Reports. 9, 12 p., 11623.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation

Ibrahim-Kosta, M., Suchon, P., Couturaud, F., Smadja, D., Olaso, R., Germain, M., Saut, N., Goumidi, L., Derbois, C., Thibord, F., Debette, S., Amouyel, P., Deleuze, J. F., van Doorn, P., Castoldi, E., Patin, E., Alessi, M. C., Tregouet, D. A. & Morange, P. E., 6 Mar 2019, In : Scientific Reports. 9, 7 p., 3750.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access